TreeWAS – Variant ID: rs12208357

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z96.1 Presence of intraocular lens	0.202	0.798	0.000
H65-H75 Diseases of middle ear and mastoid	0.050	0.950	0.000
H65 Nonsuppurative otitis media	0.049	0.951	0.000
H71 Cholesteatoma of middle ear	0.046	0.954	0.000
H72 Perforation of tympanic membrane	0.044	0.956	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.043	0.957	0.000
H65.2 Chronic serous otitis media	0.043	0.957	0.000
H74 Other disorders of middle ear and mastoid	0.043	0.957	0.000
H66 Suppurative and unspecified otitis media	0.041	0.959	0.000
H65.3 Chronic mucoid otitis media	0.041	0.959	0.000
C61 Malignant neoplasm of prostate	0.039	0.961	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.039	0.961	0.000
H70 Mastoiditis and related conditions	0.038	0.962	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.038	0.962	0.000
H69 Other disorders of Eustachian tube	0.037	0.963	0.000
H72.8 Other perforations of tympanic membrane	0.036	0.963	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.036	0.964	0.000
H68 Eustachian salpingitis and obstruction	0.036	0.964	0.000
H67 Otitis media in diseases classified elsewhere	0.036	0.964	0.000
H72.1 Attic perforation of tympanic membrane	0.036	0.964	0.000
H73 Other disorders of tympanic membrane	0.036	0.964	0.000
H65.4 Other chronic nonsuppurative otitis media	0.036	0.964	0.000
H65.1 Other acute nonsuppurative otitis media	0.035	0.965	0.000
H65.0 Acute serous otitis media	0.035	0.965	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.035	0.965	0.000
H66.9 Otitis media, unspecified	0.033	0.967	0.000
H74.0 Tympanosclerosis	0.033	0.967	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.032	0.968	0.000
H72.2 Other marginal perforations of tympanic membrane	0.032	0.968	0.000
H70.8 Other mastoiditis and related conditions	0.031	0.969	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.031	0.969	0.000
H74.1 Adhesive middle ear disease	0.031	0.969	0.000
H66.3 Other chronic suppurative otitis media	0.030	0.970	0.000
H66.4 Suppurative otitis media, unspecified	0.030	0.970	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.030	0.970	0.000
H66.0 Acute suppurative otitis media	0.030	0.970	0.000
M51.2 Other specified intervertebral disk displacement	0.028	0.972	0.000
H69.9 Eustachian tube disorder, unspecified	0.028	0.972	0.000
H72.0 Central perforation of tympanic membrane	0.028	0.972	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.028	0.972	0.000
H70.2 Petrositis	0.027	0.972	0.000
H70.1 Chronic mastoiditis	0.027	0.972	0.000
H70.0 Acute mastoiditis	0.027	0.972	0.000
H69.8 Other specified disorders of Eustachian tube	0.027	0.973	0.000
H69.0 Patulous Eustachian tube	0.027	0.973	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.026	0.974	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.026	0.974	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.026	0.974	0.000
H68.1 Obstruction of Eustachian tube	0.026	0.974	0.000
H68.0 Eustachian salpingitis	0.026	0.974	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.026	0.974	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.026	0.974	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.026	0.974	0.000
H73.1 Chronic myringitis	0.026	0.974	0.000
H73.0 Acute myringitis	0.026	0.974	0.000
H73.8 Other specified disorders of tympanic membrane	0.026	0.974	0.000
H70.9 Mastoiditis, unspecified	0.025	0.975	0.000
H74.4 Polyp of middle ear	0.023	0.977	0.000
M51 Other intervertebral disk disorders	0.021	0.979	0.000
Z96 Presence of other functional implants	0.021	0.979	0.000
M51.8 Other specified intervertebral disk disorders	0.020	0.979	0.000
B34.9 Viral infection, unspecified	0.020	0.980	0.000
Chapter VIII Diseases of the ear and mastoid process	0.019	0.981	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.982	0.018
Z96.2 Presence of otological and audiological implants	0.017	0.983	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.016	0.984	0.000
M51.3 Other specified intervertebral disk degeneration	0.015	0.985	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.015	0.985	0.000
M51.4 Schmorl's nodes	0.015	0.985	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.015	0.985	0.000
Z96.4 Presence of endocrine implants	0.015	0.985	0.000
Z96.3 Presence of artificial larynx	0.015	0.985	0.000
Z96.9 Presence of functional implant, unspecified	0.015	0.985	0.000
Z96.7 Presence of other bone and tendon implants	0.015	0.985	0.000
H90-H95 Other disorders of ear	0.014	0.986	0.000
C60-C63 Malignant neoplasms of male genital organs	0.014	0.986	0.000
B34 Viral infection of unspecified site	0.014	0.986	0.000
H60-H62 Diseases of external ear	0.014	0.986	0.000
Z96.8 Presence of other specified functional implants	0.013	0.987	0.000
M51.9 Intervertebral disk disorder, unspecified	0.013	0.987	0.000
H80-H83 Diseases of inner ear	0.013	0.987	0.000
B34.4 Papovirus infection, unspecified	0.012	0.988	0.000
H92 Otalgia and effusion of ear	0.012	0.988	0.000
H61 Other disorders of external ear	0.011	0.989	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.011	0.989	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.011	0.989	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.011	0.989	0.000
H93 Other disorders of ear, not elsewhere classified	0.011	0.989	0.000
H90 Conductive and sensorineural hearing loss	0.010	0.989	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.010	0.989	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.010	0.990	0.000
C60 Malignant neoplasm of penis	0.010	0.990	0.000
B34.3 Parvovirus infection, unspecified	0.010	0.990	0.000
B34.2 Coronavirus infection, unspecified	0.010	0.990	0.000
B34.1 Enterovirus infection, unspecified	0.010	0.990	0.000
B34.0 Adenovirus infection, unspecified	0.010	0.990	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.010	0.990	0.000
B34.8 Other viral infections of unspecified site	0.010	0.990	0.000
H92.1 Otorrhoea	0.010	0.990	0.000
H91 Other hearing loss	0.010	0.990	0.000
H61.1 Non-infective disorders of pinna	0.010	0.990	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.010	0.990	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.991	0.009
H81 Disorders of vestibular function	0.009	0.991	0.000
H80 Otosclerosis	0.009	0.991	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.009	0.991	0.000
H61.3 Acquired stenosis of external ear canal	0.009	0.991	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.009	0.991	0.000
C62 Malignant neoplasm of testis	0.009	0.991	0.000
H93.8 Other specified disorders of ear	0.009	0.991	0.000
I42.0 Dilated cardiomyopathy	0.000	0.991	0.009
H61.8 Other specified disorders of external ear	0.009	0.991	0.000
H90.2 Conductive hearing loss, unspecified	0.009	0.991	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.991	0.009
I42 Cardiomyopathy	0.000	0.991	0.009
H92.2 Otorrhagia	0.008	0.991	0.000
H61.0 Perichondritis of external ear	0.008	0.991	0.000
H91.1 Presbycusis	0.008	0.992	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.008	0.992	0.000
H61.9 Disorder of external ear, unspecified	0.008	0.992	0.000
H92.0 Otalgia	0.008	0.992	0.000
H93.9 Disorder of ear, unspecified	0.008	0.992	0.000
H93.3 Disorders of acoustic nerve	0.008	0.992	0.000
H93.2 Other abnormal auditory perceptions	0.008	0.992	0.000
H93.0 Degenerative and vascular disorders of ear	0.008	0.992	0.000
H81.0 Meniere's disease	0.008	0.992	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.008	0.992	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
C60.9 Penis, unspecified	0.008	0.992	0.000
C60.8 Overlapping lesion of penis	0.008	0.992	0.000
C60.2 Body of penis	0.008	0.992	0.000
C60.1 Glans penis	0.008	0.992	0.000
C60.0 Prepuce	0.008	0.992	0.000
C63.9 Male genital organ, unspecified	0.008	0.992	0.000
C63.8 Overlapping lesion of male genital organs	0.008	0.992	0.000
C63.7 Other specified male genital organs	0.008	0.992	0.000
C63.2 Scrotum	0.008	0.992	0.000
C63.1 Spermatic cord	0.008	0.992	0.000
C63.0 Epididymis	0.008	0.992	0.000
H90.5 Sensorineural hearing loss, unspecified	0.008	0.992	0.000
H60 Otitis externa	0.008	0.992	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.008	0.992	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.007	0.992	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.007	0.992	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
H62.2 Otitis externa in mycoses	0.007	0.992	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.007	0.992	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.007	0.992	0.000
H81.9 Disorder of vestibular function, unspecified	0.007	0.992	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.992	0.007
H91.3 Deaf mutism, not elsewhere classified	0.007	0.993	0.000
H91.2 Sudden idiopathic hearing loss	0.007	0.993	0.000
H91.0 Ototoxic hearing loss	0.007	0.993	0.000
I42.8 Other cardiomyopathies	0.000	0.993	0.007
H83 Other diseases of inner ear	0.007	0.993	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.007	0.993	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.007	0.993	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.007	0.993	0.000
H91.8 Other specified hearing loss	0.007	0.993	0.000
H81.1 Benign paroxysmal vertigo	0.007	0.993	0.000
H61.2 Impacted cerumen	0.007	0.993	0.000
H80.9 Otosclerosis, unspecified	0.007	0.993	0.000
H90.0 Conductive hearing loss, bilateral	0.007	0.993	0.000
B25-B34 Other viral diseases	0.007	0.993	0.000
H80.8 Other otosclerosis	0.007	0.993	0.000
H80.2 Cochlear otosclerosis	0.007	0.993	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.007	0.993	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.007	0.993	0.000
H81.8 Other disorders of vestibular function	0.007	0.993	0.000
H81.4 Vertigo of central origin	0.007	0.993	0.000
H81.3 Other peripheral vertigo	0.007	0.993	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
C62.1 Descended testis	0.007	0.993	0.000
C62.0 Undescended testis	0.007	0.993	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.993	0.007
S42.20 Fracture of upper end of humerus (closed)	0.007	0.993	0.000
Z96.6 Presence of orthopaedic joint implants	0.007	0.993	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.993	0.006
I42.6 Alcoholic cardiomyopathy	0.000	0.993	0.006
I42.5 Other restrictive cardiomyopathy	0.000	0.993	0.006
I42.4 Endocardial fibroelastosis	0.000	0.993	0.006
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.993	0.006
I83 Varicose veins of lower extremities	0.000	0.993	0.006
H95.1 Other disorders following mastoidectomy	0.006	0.994	0.000
H93.1 Tinnitus	0.006	0.994	0.000
H60.3 Other infective otitis externa	0.006	0.994	0.000
T92.1 Sequelae of fracture of arm	0.006	0.994	0.000
S42.2 Fracture of upper end of humerus	0.006	0.994	0.000
T92 Sequelae of injuries of upper limb	0.006	0.994	0.000
B25 Cytomegaloviral disease	0.006	0.994	0.000
H60.8 Other otitis externa	0.006	0.994	0.000
H60.5 Acute otitis externa, non-infective	0.006	0.994	0.000
H60.4 Cholesteatoma of external ear	0.006	0.994	0.000
H60.2 Malignant otitis externa	0.006	0.994	0.000
H60.0 Abscess of external ear	0.006	0.994	0.000
C62.9 Testis, unspecified	0.005	0.994	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.994	0.006
S42 Fracture of shoulder and upper arm	0.006	0.994	0.000
Z96.0 Presence of urogenital implants	0.006	0.994	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.005	0.994	0.000
H83.9 Disease of inner ear, unspecified	0.005	0.994	0.000
H83.8 Other specified diseases of inner ear	0.005	0.994	0.000
H83.3 Noise effects on inner ear	0.005	0.994	0.000
H83.2 Labyrinthine dysfunction	0.005	0.994	0.000
H83.1 Labyrinthine fistula	0.005	0.994	0.000
S40-S49 Injuries to the shoulder and upper arm	0.005	0.995	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.005	0.995	0.000
H91.9 Hearing loss, unspecified	0.005	0.995	0.000
S22.0 Fracture of thoracic vertebra	0.005	0.995	0.000
B33 Other viral diseases, not elsewhere classified	0.005	0.995	0.000
B30 Viral conjunctivitis	0.005	0.995	0.000
B27 Infectious mononucleosis	0.005	0.995	0.000
B26 Mumps	0.005	0.995	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.005	0.995	0.000
T92.0 Sequelae of open wound of upper limb	0.005	0.995	0.000
S40 Superficial injury of shoulder and upper arm	0.005	0.995	0.000
S20-S29 Injuries to the thorax	0.005	0.995	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.995	0.005
H81.2 Vestibular neuronitis	0.005	0.995	0.000
B25.9 Cytomegaloviral disease, unspecified	0.005	0.995	0.000
S13.4 Sprain and strain of cervical spine	0.005	0.995	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.005	0.995	0.000
S10-S19 Injuries to the neck	0.005	0.995	0.000
H60.1 Cellulitis of external ear	0.005	0.995	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.995	0.005
T92.9 Sequelae of unspecified injury of upper limb	0.005	0.995	0.000
R51 Headache	0.000	0.995	0.005
C34.9 Bronchus or lung, unspecified	0.000	0.995	0.005
S42.3 Fracture of shaft of humerus	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.004	0.995	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.005	0.995	0.000
F03 Unspecified dementia	0.005	0.995	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.005	0.995	0.000
S92 Fracture of foot, except ankle	0.005	0.995	0.000
S22.3 Fracture of rib	0.005	0.995	0.000
S22.1 Multiple fractures of thoracic spine	0.005	0.995	0.000
S42.21 Fracture of upper end of humerus (open)	0.004	0.995	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.005	0.995	0.000
S50-S59 Injuries to the elbow and forearm	0.005	0.995	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.004	0.995	0.000
S22.4 Multiple fractures of ribs	0.004	0.995	0.000
S42.4 Fracture of lower end of humerus	0.004	0.995	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.004	0.995	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.004	0.995	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.004	0.995	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.004	0.995	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.995	0.004
T93 Sequelae of injuries of lower limb	0.004	0.995	0.000
B25.8 Other cytomegaloviral diseases	0.004	0.996	0.000
B25.2 Cytomegaloviral pancreatitis	0.004	0.996	0.000
B25.1 Cytomegaloviral hepatitis	0.004	0.996	0.000
B25.0 Cytomegaloviral pneumonitis	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
S92.0 Fracture of calcaneus	0.004	0.996	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.004	0.996	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.996	0.004
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.004	0.996	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.004	0.996	0.000
S64 Injury of nerves at wrist and hand level	0.004	0.996	0.000
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.996	0.004
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
S12 Fracture of neck	0.004	0.996	0.000
T98 Sequelae of other and unspecified effects of external causes	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.004	0.996	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.004	0.996	0.000
S48 Traumatic amputation of shoulder and upper arm	0.004	0.996	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S44 Injury of nerves at shoulder and upper arm level	0.004	0.996	0.000
S47 Crushing injury of shoulder and upper arm	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.004	0.996	0.000
S22.8 Fracture of other parts of bony thorax	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
S22.01 Fracture of thoracic vertebra (open)	0.004	0.996	0.000
S21 Open wound of thorax	0.004	0.996	0.000
B26.9 Mumps without complication	0.004	0.996	0.000
B26.8 Mumps with other complications	0.004	0.996	0.000
B26.3 Mumps pancreatitis	0.004	0.996	0.000
B26.2 Mumps encephalitis	0.004	0.996	0.000
B26.1 Mumps meningitis	0.004	0.996	0.000
B26.0 Mumps orchitis	0.004	0.996	0.000
B27.9 Infectious mononucleosis, unspecified	0.004	0.996	0.000
B27.8 Other infectious mononucleosis	0.004	0.996	0.000
B27.1 Cytomegaloviral mononucleosis	0.004	0.996	0.000
B27.0 Gammaherpesviral mononucleosis	0.004	0.996	0.000
B30.9 Viral conjunctivitis, unspecified	0.004	0.996	0.000
B30.8 Other viral conjunctivitis	0.004	0.996	0.000
B30.3 Acute epidemic haemorrhagic conjunctivitis (enteroviral)	0.004	0.996	0.000
B30.2 Viral pharyngoconjunctivitis	0.004	0.996	0.000
B30.1 Conjunctivitis due to adenovirus	0.004	0.996	0.000
B30.0 Keratoconjunctivitis due to adenovirus	0.004	0.996	0.000
B33.8 Other specified viral diseases	0.004	0.996	0.000
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.004	0.996	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.004	0.996	0.000
B33.2 Viral carditis	0.004	0.996	0.000
B33.1 Ross River disease	0.004	0.996	0.000
B33.0 Epidemic myalgia	0.004	0.996	0.000
F02 Dementia in other diseases classified elsewhere	0.004	0.996	0.000
S92.1 Fracture of talus	0.004	0.996	0.000
S19 Other and unspecified injuries of neck	0.004	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
S41 Open wound of shoulder and upper arm	0.004	0.996	0.000
S50 Superficial injury of forearm	0.004	0.996	0.000
S20 Superficial injury of thorax	0.004	0.996	0.000
F02.3 Dementia in Parkinson's disease	0.004	0.996	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.004	0.996	0.000
H60.9 Otitis externa, unspecified	0.004	0.996	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
C34.0 Main bronchus	0.000	0.996	0.004
S51 Open wound of forearm	0.004	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.004	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.004	0.996	0.000
S51.0 Open wound of elbow	0.004	0.996	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.004	0.996	0.000
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.004	0.996	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.004	0.996	0.000
S54 Injury of nerves at forearm level	0.004	0.996	0.000
F02.0 Dementia in Pick's disease	0.004	0.996	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.004	0.996	0.000
S26 Injury of heart	0.004	0.996	0.000
S25 Injury of blood vessels of thorax	0.004	0.996	0.000
S24 Injury of nerves and spinal cord at thorax level	0.004	0.996	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.004	0.996	0.000
S29 Other and unspecified injuries of thorax	0.004	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.004	0.996	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.004	0.996	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.996	0.004
S14 Injury of nerves and spinal cord at neck level	0.004	0.996	0.000
S10 Superficial injury of neck	0.004	0.996	0.000
S22.40 Multiple fractures of ribs (closed)	0.004	0.996	0.000
S13.5 Sprain and strain of thyroid region	0.004	0.996	0.000
S13.3 Multiple dislocations of neck	0.004	0.996	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.004	0.996	0.000
S13.1 Dislocation of cervical vertebra	0.004	0.996	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.004	0.996	0.000
S17 Crushing injury of neck	0.004	0.996	0.000
S15 Injury of blood vessels at neck level	0.004	0.996	0.000
S11 Open wound of neck	0.004	0.996	0.000
S18 Traumatic amputation at neck level	0.004	0.996	0.000
S16 Injury of muscle and tendon at neck level	0.004	0.996	0.000
S27 Injury of other and unspecified intrathoracic organs	0.004	0.996	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.004	0.996	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.004	0.996	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.996	0.004
S56 Injury of muscle and tendon at forearm level	0.004	0.996	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.004	0.996	0.000
T21 Burn and corrosion of trunk	0.004	0.996	0.000
S42.31 Fracture of shaft of humerus (open)	0.004	0.996	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.004	0.996	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.004	0.996	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.004	0.996	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.004	0.996	0.000
S12.1 Fracture of second cervical vertebra	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.004	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.004	0.996	0.000
S22.31 Fracture of rib (open)	0.003	0.996	0.000
S42.40 Fracture of lower end of humerus (closed)	0.004	0.996	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.004	0.996	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.004	0.996	0.000
S59 Other and unspecified injuries of forearm	0.004	0.996	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.996	0.000
J33.9 Nasal polyp, unspecified	0.004	0.996	0.000
S20.3 Other superficial injuries of front wall of thorax	0.004	0.996	0.000
T91.1 Sequelae of fracture of spine	0.004	0.996	0.000
S68 Traumatic amputation of wrist and hand	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
S42.1 Fracture of scapula	0.003	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.996	0.000
T33-T35 Frostbite	0.003	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.996	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.996	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.003	0.996	0.000
S58 Traumatic amputation of forearm	0.003	0.996	0.000
S57 Crushing injury of forearm	0.003	0.996	0.000
S55 Injury of blood vessels at forearm level	0.003	0.996	0.000
S50.9 Superficial injury of forearm, unspecified	0.003	0.996	0.000
T90 Sequelae of injuries of head	0.003	0.996	0.000
M80-M85 Disorders of bone density and structure	0.003	0.996	0.000
S22.41 Multiple fractures of ribs (open)	0.003	0.996	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.003	0.996	0.000
S42.41 Fracture of lower end of humerus (open)	0.003	0.996	0.000
S19.9 Unspecified injury of neck	0.003	0.996	0.000
S54.0 Injury of ulnar nerve at forearm level	0.003	0.996	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.996	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.996	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.996	0.000
T14 Injury of unspecified body region	0.003	0.996	0.000
T20 Burn and corrosion of head and neck	0.003	0.996	0.000
S21.2 Open wound of back wall of thorax	0.003	0.997	0.000
M50-M54 Other dorsopathies	0.003	0.997	0.000
T79-T79 Certain early complications of trauma	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
H83.0 Labyrinthitis	0.003	0.997	0.000
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.003	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.003	0.997	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.003	0.997	0.000
S64.8 Injury of other nerves at wrist and hand level	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.003	0.997	0.000
I77.6 Arteritis, unspecified	0.000	0.997	0.003
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.997	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.997	0.000
Y83.8 Other surgical procedures	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.003	0.997	0.000
T98.2 Sequelae of certain early complications of trauma	0.003	0.997	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.003	0.997	0.000
S12.9 Fracture of neck, part unspecified	0.003	0.997	0.000
S12.8 Fracture of other parts of neck	0.003	0.997	0.000
S12.0 Fracture of first cervical vertebra	0.003	0.997	0.000
S51.7 Multiple open wounds of forearm	0.003	0.997	0.000
S20.2 Contusion of thorax	0.003	0.997	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.003	0.997	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.003	0.997	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.003	0.997	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.003	0.997	0.000
S44.4 Injury of musculocutaneous nerve	0.003	0.997	0.000
S44.3 Injury of axillary nerve	0.003	0.997	0.000
S44.2 Injury of radial nerve at upper arm level	0.003	0.997	0.000
S44.1 Injury of median nerve at upper arm level	0.003	0.997	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.003	0.997	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.003	0.997	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.003	0.997	0.000
S45.2 Injury of axillary or brachial vein	0.003	0.997	0.000
S45.1 Injury of brachial artery	0.003	0.997	0.000
S45.0 Injury of axillary artery	0.003	0.997	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.003	0.997	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.003	0.997	0.000
S48.0 Traumatic amputation at shoulder joint	0.003	0.997	0.000
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
S22.50 Flail chest (closed)	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations