TreeWAS – Variant ID: rs12280753

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.766	0.234	0.000
E78.2 Mixed hyperlipidaemia	0.691	0.309	0.000
E78.4 Other hyperlipidaemia	0.690	0.310	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.622	0.378	0.000
E78.1 Pure hyperglyceridaemia	0.552	0.448	0.000
E78.6 Lipoprotein deficiency	0.549	0.451	0.000
E78.3 Hyperchylomicronaemia	0.549	0.451	0.000
E78.8 Other disorders of lipoprotein metabolism	0.522	0.478	0.000
E78.5 Hyperlipidaemia, unspecified	0.235	0.765	0.000
I63 Cerebral infarction	0.000	0.895	0.105
I63.9 Cerebral infarction, unspecified	0.000	0.896	0.104
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.902	0.098
I60-I69 Cerebrovascular diseases	0.000	0.904	0.096
I69 Sequelae of cerebrovascular disease	0.000	0.904	0.096
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.909	0.091
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.914	0.086
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.915	0.085
I62 Other nontraumatic intracranial haemorrhage	0.000	0.919	0.081
I69.3 Sequelae of cerebral infarction	0.000	0.919	0.081
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.920	0.080
I63.8 Other cerebral infarction	0.000	0.921	0.079
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.923	0.077
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.925	0.075
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.925	0.075
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.925	0.075
I61 Intracerebral haemorrhage	0.000	0.925	0.075
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.927	0.073
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.930	0.070
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.931	0.069
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.931	0.069
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.931	0.069
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.931	0.069
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.932	0.068
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.935	0.065
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.938	0.062
I62.1 Nontraumatic extradural haemorrhage	0.000	0.942	0.058
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.946	0.054
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.946	0.054
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.946	0.054
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.946	0.054
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.946	0.054
I60 Subarachnoid haemorrhage	0.000	0.947	0.053
I61.8 Other intracerebral haemorrhage	0.000	0.948	0.052
I67 Other cerebrovascular diseases	0.000	0.948	0.052
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.950	0.050
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.950	0.050
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.950	0.050
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.950	0.050
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.950	0.050
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.950	0.050
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.950	0.050
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.950	0.050
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.950	0.050
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.950	0.050
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.950	0.050
I68.0 Cerebral amyloid angiopathy	0.000	0.950	0.050
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.952	0.048
I67.1 Cerebral aneurysm, nonruptured	0.000	0.954	0.046
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.957	0.043
I60.8 Other subarachnoid haemorrhage	0.000	0.959	0.041
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.961	0.039
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.962	0.038
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.962	0.038
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.962	0.038
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.962	0.038
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.963	0.037
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.963	0.037
I67.5 Moyamoya disease	0.000	0.963	0.037
I67.4 Hypertensive encephalopathy	0.000	0.963	0.037
I67.3 Progressive vascular leukoencephalopathy	0.000	0.963	0.037
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.968	0.032
I67.2 Cerebral atherosclerosis	0.000	0.968	0.032
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.969	0.031
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.969	0.031
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.969	0.031
I65.1 Occlusion and stenosis of basilar artery	0.000	0.969	0.031
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.969	0.031
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.969	0.030
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.970	0.030
I67.8 Other specified cerebrovascular diseases	0.000	0.971	0.029
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.973	0.027
I67.9 Cerebrovascular disease, unspecified	0.000	0.976	0.024
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.978	0.022
R40.0 Somnolence	0.014	0.986	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.987	0.013
E70-E90 Metabolic disorders	0.012	0.988	0.000
R45.8 Other symptoms and signs involving emotional state	0.012	0.988	0.000
R40 Somnolence, stupor and coma	0.012	0.988	0.000
R45 Symptoms and signs involving emotional state	0.011	0.989	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.010	0.990	0.000
D73.0 Hyposplenism	0.000	0.990	0.010
E85 Amyloidosis	0.009	0.991	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.991	0.008
E80 Disorders of porphyrin and bilirubin metabolism	0.009	0.991	0.000
D75.1 Secondary polycythaemia	0.000	0.991	0.009
E84 Cystic fibrosis	0.009	0.991	0.000
E79 Disorders of purine and pyrimidine metabolism	0.009	0.991	0.000
E77 Disorders of glycoprotein metabolism	0.009	0.991	0.000
E76 Disorders of glycosaminoglycan metabolism	0.009	0.991	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.009	0.991	0.000
E72 Other disorders of amino-acid metabolism	0.009	0.991	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.009	0.991	0.000
E70 Disorders of aromatic amino-acid metabolism	0.009	0.991	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.009	0.991	0.000
R45.1 Restlessness and agitation	0.009	0.991	0.000
R40.2 Coma, unspecified	0.009	0.991	0.000
R40.1 Stupor	0.008	0.991	0.000
E74 Other disorders of carbohydrate metabolism	0.008	0.991	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
D73 Diseases of spleen	0.000	0.992	0.008
R45.0 Nervousness	0.008	0.992	0.000
R45.2 Unhappiness	0.008	0.992	0.000
R45.7 State of emotional shock and stress, unspecified	0.008	0.992	0.000
R45.6 Physical violence	0.008	0.992	0.000
R45.5 Hostility	0.008	0.992	0.000
R45.4 Irritability and anger	0.008	0.992	0.000
R45.3 Demoralisation and apathy	0.008	0.992	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.008	0.992	0.000
H04 Disorders of lachrymal system	0.000	0.992	0.008
R44 Other symptoms and signs involving general sensations and perceptions	0.008	0.992	0.000
E73 Lactose intolerance	0.007	0.992	0.000
R41.3 Other amnesia	0.008	0.992	0.000
E80.6 Other disorders of bilirubin metabolism	0.007	0.992	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.007	0.993	0.000
R43 Disturbances of smell and taste	0.007	0.993	0.000
R46 Symptoms and signs involving appearance and behaviour	0.007	0.993	0.000
E85.9 Amyloidosis, unspecified	0.007	0.993	0.000
D75.2 Essential thrombocytosis	0.000	0.993	0.007
R44.1 Visual hallucinations	0.007	0.993	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.993	0.007
E85.4 Organ-limited amyloidosis	0.007	0.993	0.000
E85.8 Other amyloidosis	0.007	0.993	0.000
E85.3 Secondary systemic amyloidosis	0.007	0.993	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.007	0.993	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.007	0.993	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.007	0.993	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.993	0.007
E88 Other metabolic disorders	0.007	0.993	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.993	0.007
E80.7 Disorder of bilirubin metabolism, unspecified	0.006	0.993	0.000
E80.5 Crigler-Najjar syndrome	0.006	0.993	0.000
E80.3 Defects of catalase and peroxydase	0.006	0.993	0.000
E80.2 Other porphyria	0.006	0.993	0.000
E80.1 Porphyria cutanea tarda	0.006	0.993	0.000
E80.0 Hereditary erythropoietic porphyria	0.006	0.993	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.006	0.993	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.006	0.993	0.000
E70.3 Albinism	0.006	0.993	0.000
E70.2 Disorders of tyrosine metabolism	0.006	0.993	0.000
E70.1 Other hyperphenylalaninaemias	0.006	0.993	0.000
E70.0 Classical phenylketonuria	0.006	0.993	0.000
E71.3 Disorders of fatty-acid metabolism	0.006	0.993	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.006	0.993	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.006	0.993	0.000
E71.0 Maple-syrup-urine disease	0.006	0.993	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.006	0.993	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.006	0.993	0.000
E72.5 Disorders of glycine metabolism	0.006	0.993	0.000
E72.4 Disorders of ornithine metabolism	0.006	0.993	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.006	0.993	0.000
E72.2 Disorders of urea cycle metabolism	0.006	0.993	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.006	0.993	0.000
E72.0 Disorders of amino-acid transport	0.006	0.993	0.000
E75.6 Lipid storage disorder, unspecified	0.006	0.993	0.000
E75.5 Other lipid storage disorders	0.006	0.993	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.006	0.993	0.000
E75.3 Sphingolipidosis, unspecified	0.006	0.993	0.000
E75.2 Other sphingolipidosis	0.006	0.993	0.000
E75.1 Other gangliosidosis	0.006	0.993	0.000
E75.0 GM2 gangliosidosis	0.006	0.993	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.006	0.993	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.006	0.993	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.006	0.993	0.000
E76.2 Other mucopolysaccharidoses	0.006	0.993	0.000
E76.1 Mucopolysaccharidosis, type II	0.006	0.993	0.000
E76.0 Mucopolysaccharidosis, type I	0.006	0.993	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.006	0.993	0.000
E77.8 Other disorders of glycoprotein metabolism	0.006	0.993	0.000
E77.1 Defects in glycoprotein degradation	0.006	0.993	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.006	0.993	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.006	0.993	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.006	0.993	0.000
E79.1 Lesch-Nyhan syndrome	0.006	0.993	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.006	0.993	0.000
E84.9 Cystic fibrosis, unspecified	0.006	0.993	0.000
E84.8 Cystic fibrosis with other manifestations	0.006	0.993	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.006	0.993	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.006	0.993	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.007	0.993	0.000
D73.5 Infarction of spleen	0.000	0.993	0.006
R41.1 Anterograde amnesia	0.006	0.993	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.994	0.006
E74.9 Disorder of carbohydrate metabolism, unspecified	0.006	0.994	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.006	0.994	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.006	0.994	0.000
E74.2 Disorders of galactose metabolism	0.006	0.994	0.000
E74.1 Disorders of fructose metabolism	0.006	0.994	0.000
E74.0 Glycogen storage disease	0.006	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.994	0.006
E89.3 Postprocedural hypopituitarism	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.000	0.994	0.006
D73.9 Disease of spleen, unspecified	0.000	0.994	0.006
D73.8 Other diseases of spleen	0.000	0.994	0.006
D73.4 Cyst of spleen	0.000	0.994	0.006
D73.3 Abscess of spleen	0.000	0.994	0.006
D73.2 Chronic congestive splenomegaly	0.000	0.994	0.006
D73.1 Hypersplenism	0.000	0.994	0.006
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.006	0.994	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.994	0.006
E74.3 Other disorders of intestinal carbohydrate absorption	0.006	0.994	0.000
H04.8 Other disorders of lachrymal system	0.000	0.994	0.006
E89.2 Postprocedural hypoparathyroidism	0.006	0.994	0.000
H04.2 Epiphora	0.000	0.994	0.006
H04.6 Other changes in lachrymal passages	0.000	0.994	0.006
H04.0 Dacryoadenitis	0.000	0.994	0.006
R44.2 Other hallucinations	0.006	0.994	0.000
H04.4 Chronic inflammation of lachrymal passages	0.000	0.994	0.006
R44.0 Auditory hallucinations	0.006	0.994	0.000
E73.8 Other lactose intolerance	0.006	0.994	0.000
E73.1 Secondary lactase deficiency	0.006	0.994	0.000
E73.0 Congenital lactase deficiency	0.006	0.994	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.994	0.006
Z13.9 Special screening examination, unspecified	0.000	0.994	0.006
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.005	0.994	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.005	0.994	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.005	0.994	0.000
E89.5 Postprocedural testicular hypofunction	0.005	0.994	0.000
E89.4 Postprocedural ovarian failure	0.005	0.994	0.000
E89.1 Postprocedural hypoinsulinaemia	0.005	0.994	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.005	0.994	0.000
R43.2 Parageusia	0.005	0.994	0.000
R43.1 Parosmia	0.005	0.994	0.000
R43.0 Anosmia	0.005	0.994	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.995	0.005
R46.8 Other symptoms and signs involving appearance and behaviour	0.005	0.995	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.005	0.995	0.000
R46.6 Undue concern and preoccupation with stressful events	0.005	0.995	0.000
R46.5 Suspiciousness and marked evasiveness	0.005	0.995	0.000
R46.4 Slowness and poor responsiveness	0.005	0.995	0.000
R46.3 Overactivity	0.005	0.995	0.000
R46.2 Strange and inexplicable behaviour	0.005	0.995	0.000
R46.1 Bizarre personal appearance	0.005	0.995	0.000
R46.0 Very low level of personal hygiene	0.005	0.995	0.000
E80.4 Gilbert's syndrome	0.005	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.995	0.005
D74 Methaemoglobinaemia	0.000	0.995	0.005
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.995	0.005
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.995	0.005
G81.9 Hemiplegia, unspecified	0.000	0.995	0.005
D70 Agranulocytosis	0.000	0.995	0.005
C78.7 Secondary malignant neoplasm of liver	0.000	0.995	0.005
E88.9 Metabolic disorder, unspecified	0.005	0.995	0.000
E88.8 Other specified metabolic disorders	0.005	0.995	0.000
E88.3 Tumour lysis syndrome	0.005	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.005	0.995	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.005	0.995	0.000
H04.9 Disorder of lachrymal system, unspecified	0.000	0.995	0.005
R41.2 Retrograde amnesia	0.005	0.995	0.000
E83 Disorders of mineral metabolism	0.005	0.995	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.995	0.000
D72 Other disorders of white blood cells	0.000	0.995	0.004
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.995	0.005
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.996	0.004
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.996	0.004
E83.1 Disorders of iron metabolism	0.004	0.996	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.996	0.004
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.996	0.004
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.996	0.004
D74.9 Methaemoglobinaemia, unspecified	0.000	0.996	0.004
D74.8 Other methaemoglobinaemias	0.000	0.996	0.004
D74.0 Congenital methaemoglobinaemia	0.000	0.996	0.004
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.996	0.004
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.996	0.004
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.996	0.004
D76.3 Other histiocytosis syndromes	0.000	0.996	0.004
R44.3 Hallucinations, unspecified	0.004	0.996	0.000
G81 Hemiplegia	0.000	0.996	0.004
C54.1 Endometrium	0.000	0.996	0.004
E83.9 Disorder of mineral metabolism, unspecified	0.004	0.996	0.000
E83.8 Other disorders of mineral metabolism	0.004	0.996	0.000
E83.2 Disorders of zinc metabolism	0.004	0.996	0.000
E83.0 Disorders of copper metabolism	0.004	0.996	0.000
R42 Dizziness and giddiness	0.004	0.996	0.000
N60.2 Fibroadenosis of breast	0.004	0.996	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.996	0.003
D72.0 Genetic anomalies of leukocytes	0.000	0.996	0.003
Z83.7 Family history of diseases of the digestive system	0.003	0.997	0.000
Y95 Nosocomial condition	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
D72.1 Eosinophilia	0.000	0.997	0.003
E53.9 Vitamin B deficiency, unspecified	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.003	0.997	0.001
E83.3 Disorders of phosphorus metabolism	0.003	0.997	0.000
E50-E64 Other nutritional deficiencies	0.003	0.997	0.000
G81.1 Spastic hemiplegia	0.000	0.997	0.003
G81.0 Flaccid hemiplegia	0.000	0.997	0.003
R41.0 Disorientation, unspecified	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.997	0.003
G83.4 Cauda equina syndrome	0.000	0.997	0.003
N60 Benign mammary dysplasia	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.003	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.997	0.003
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.997	0.003
G83 Other paralytic syndromes	0.000	0.997	0.003
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
E83.4 Disorders of magnesium metabolism	0.003	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
R35 Polyuria	0.003	0.997	0.000
G82 Paraplegia and tetraplegia	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.003	0.997	0.000
N42.8 Other specified disorders of prostate	0.000	0.997	0.003
N60.9 Benign mammary dysplasia, unspecified	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
N23 Unspecified renal colic	0.000	0.997	0.003
E55 Vitamin D deficiency	0.003	0.997	0.000
I95.1 Orthostatic hypotension	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
Z63 Other problems related to primary support group, including family circumstances	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.003	0.997	0.000
N62 Hypertrophy of breast	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.997	0.000
E63 Other nutritional deficiencies	0.002	0.997	0.000
E56 Other vitamin deficiencies	0.002	0.997	0.000
E51 Thiamine deficiency	0.002	0.997	0.000
E50 Vitamin A deficiency	0.002	0.997	0.000
E60 Dietary zinc deficiency	0.002	0.997	0.000
E59 Dietary selenium deficiency	0.002	0.997	0.000
E58 Dietary calcium deficiency	0.002	0.997	0.000
E54 Ascorbic acid deficiency	0.002	0.997	0.000
E52 Niacin deficiency [pellagra]	0.002	0.997	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
G82.5 Tetraplegia, unspecified	0.000	0.997	0.002
G83.1 Monoplegia of lower limb	0.000	0.997	0.002
N60.8 Other benign mammary dysplasias	0.002	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.997	0.000
G82.1 Spastic paraplegia	0.000	0.997	0.002
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.000	0.998	0.002
G83.3 Monoplegia, unspecified	0.000	0.998	0.002
G83.0 Diplegia of upper limbs	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.000	0.998	0.002
G83.2 Monoplegia of upper limb	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
I51.7 Cardiomegaly	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
I95.2 Hypotension due to drugs	0.000	0.998	0.002
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
E55.0 Rickets, active	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
Z60 Problems related to social environment	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
Z60.2 Living alone	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
Z60.8 Other problems related to social environment	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.000	0.998	0.002
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.000	0.998	0.002
G80.1 Spastic diplegia	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.002	0.998	0.000
I95 Hypotension	0.000	0.998	0.002
N60-N64 Disorders of breast	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.998	0.002
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
N64 Other disorders of breast	0.002	0.998	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.2 Magnesium deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
Z95.1 Presence of aortocoronary bypass graft	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
Z60.9 Problem related to social environment, unspecified	0.002	0.998	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.002	0.998	0.000
Z60.4 Social exclusion and rejection	0.002	0.998	0.000
Z60.3 Acculturation difficulty	0.002	0.998	0.000
Z60.1 Atypical parenting situation	0.002	0.998	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
E40-E46 Malnutrition	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations