TreeWAS – Variant ID: rs12297524

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F31 Bipolar affective disorder	0.000	0.869	0.131
F31.9 Bipolar affective disorder, unspecified	0.000	0.873	0.127
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.877	0.123
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.879	0.121
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.886	0.114
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.888	0.112
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.889	0.111
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.894	0.106
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.900	0.100
F31.8 Other bipolar affective disorders	0.000	0.908	0.092
F31.7 Bipolar affective disorder, currently in remission	0.000	0.910	0.090
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.034	0.966	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.979	0.021
T18.1 Foreign body in oesophagus	0.014	0.986	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.988	0.012
M89.87 Other specified disorders of bone (Ankle and foot)	0.012	0.988	0.000
M89.8 Other specified disorders of bone	0.012	0.988	0.000
M89.3 Hypertrophy of bone	0.012	0.988	0.000
E28.3 Primary ovarian failure	0.011	0.989	0.000
M89 Other disorders of bone	0.011	0.989	0.000
E28 Ovarian dysfunction	0.011	0.989	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.011	0.989	0.000
M89.9 Disorder of bone, unspecified	0.011	0.989	0.000
M89.38 Hypertrophy of bone (Other)	0.011	0.989	0.000
E28.2 Polycystic ovarian syndrome	0.010	0.990	0.000
K02.9 Dental caries, unspecified	0.010	0.990	0.000
M89.84 Other specified disorders of bone (Hand)	0.010	0.990	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
K04.5 Chronic apical periodontitis	0.000	0.990	0.010
M89.94 Disorder of bone, unspecified (Hand)	0.010	0.990	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.009	0.990	0.000
E20-E35 Disorders of other endocrine glands	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
M89.88 Other specified disorders of bone (Other)	0.009	0.991	0.000
E34 Other endocrine disorders	0.009	0.991	0.000
E24.9 Cushing's syndrome, unspecified	0.009	0.991	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.009	0.991	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.009	0.991	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.009	0.991	0.000
M89.98 Disorder of bone, unspecified (Other)	0.009	0.991	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.009	0.991	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.008	0.991	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.008	0.991	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.008	0.991	0.000
M89.34 Hypertrophy of bone (Hand)	0.008	0.991	0.000
M89.33 Hypertrophy of bone (Forearm)	0.008	0.991	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.008	0.991	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.008	0.991	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.008	0.991	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.008	0.992	0.000
M89.83 Other specified disorders of bone (Forearm)	0.008	0.992	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.008	0.992	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.008	0.992	0.000
E34.8 Other specified endocrine disorders	0.008	0.992	0.000
M89.6 Osteopathy after poliomyelitis	0.008	0.992	0.000
M89.2 Other disorders of bone development and growth	0.008	0.992	0.000
M89.1 Epiphyseal arrest	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.992	0.000
E28.8 Other ovarian dysfunction	0.008	0.992	0.000
E28.1 Androgen excess	0.008	0.992	0.000
E28.0 Oestrogen excess	0.008	0.992	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.008	0.992	0.000
E34.0 Carcinoid syndrome	0.008	0.992	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.008	0.992	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.008	0.992	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.008	0.992	0.000
T18 Foreign body in alimentary tract	0.008	0.992	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.008	0.992	0.000
M89.5 Osteolysis	0.008	0.992	0.000
F30-F39 Mood [affective] disorders	0.000	0.992	0.008
E24.8 Other Cushing's syndrome	0.008	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.008	0.992	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.007	0.992	0.000
E25 Adrenogenital disorders	0.007	0.993	0.000
E24.2 Drug-induced Cushing's syndrome	0.007	0.993	0.000
S27.0 Traumatic pneumothorax	0.000	0.993	0.007
E22.0 Acromegaly and pituitary gigantism	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
E31 Polyglandular dysfunction	0.007	0.993	0.000
E20 Hypoparathyroidism	0.007	0.993	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E32 Diseases of thymus	0.007	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.007	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.007	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.007	0.993	0.000
E24.1 Nelson's syndrome	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.993	0.007
E34.5 Androgen resistance syndrome	0.007	0.993	0.000
E34.4 Constitutional tall stature	0.007	0.993	0.000
E34.3 Short stature, not elsewhere classified	0.007	0.993	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.007	0.993	0.000
E34.1 Other hypersecretion of intestinal hormones	0.007	0.993	0.000
E22.1 Hyperprolactinaemia	0.007	0.993	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.007	0.993	0.000
E26 Hyperaldosteronism	0.006	0.993	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.006	0.993	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.006	0.993	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.006	0.993	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.006	0.993	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.006	0.993	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.006	0.993	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.006	0.993	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.006	0.993	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.006	0.993	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
T18.0 Foreign body in mouth	0.006	0.994	0.000
F34 Persistent mood [affective] disorders	0.000	0.994	0.006
M89.19 Epiphyseal arrest (Site unspecified)	0.006	0.994	0.000
M89.18 Epiphyseal arrest (Other)	0.006	0.994	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.006	0.994	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.006	0.994	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.006	0.994	0.000
M89.14 Epiphyseal arrest (Hand)	0.006	0.994	0.000
M89.13 Epiphyseal arrest (Forearm)	0.006	0.994	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.006	0.994	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.006	0.994	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.006	0.994	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.006	0.994	0.000
M89.28 Other disorders of bone development and growth (Other)	0.006	0.994	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.006	0.994	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.006	0.994	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.006	0.994	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.006	0.994	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.006	0.994	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.006	0.994	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.006	0.994	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.006	0.994	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.006	0.994	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.006	0.994	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.006	0.994	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.006	0.994	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.006	0.994	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.006	0.994	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.006	0.994	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.006	0.994	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.006	0.994	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.006	0.994	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.006	0.994	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.006	0.994	0.000
T18.4 Foreign body in colon	0.006	0.994	0.000
T18.3 Foreign body in small intestine	0.006	0.994	0.000
T18.2 Foreign body in stomach	0.006	0.994	0.000
E29 Testicular dysfunction	0.006	0.994	0.000
M89.59 Osteolysis (Site unspecified)	0.006	0.994	0.000
M89.58 Osteolysis (Other)	0.006	0.994	0.000
M89.57 Osteolysis (Ankle and foot)	0.006	0.994	0.000
M89.56 Osteolysis (Lower leg)	0.006	0.994	0.000
M89.54 Osteolysis (Hand)	0.006	0.994	0.000
M89.53 Osteolysis (Forearm)	0.006	0.994	0.000
M89.52 Osteolysis (Upper arm)	0.006	0.994	0.000
M89.51 Osteolysis (Shoulder region)	0.006	0.994	0.000
M89.50 Osteolysis (Multiple sites)	0.006	0.994	0.000
F38 Other mood [affective] disorders	0.000	0.994	0.006
K02 Dental caries	0.006	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.994	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.994	0.000
E25.8 Other adrenogenital disorders	0.005	0.994	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.995	0.000
E31.8 Other polyglandular dysfunction	0.005	0.995	0.000
E31.1 Polyglandular hyperfunction	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.005	0.995	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.995	0.005
E30.9 Disorder of puberty, unspecified	0.005	0.995	0.000
E30.8 Other disorders of puberty	0.005	0.995	0.000
E30.1 Precocious puberty	0.005	0.995	0.000
E30.0 Delayed puberty	0.005	0.995	0.000
E32.9 Disease of thymus, unspecified	0.005	0.995	0.000
E32.8 Other diseases of thymus	0.005	0.995	0.000
E32.1 Abscess of thymus	0.005	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.995	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.995	0.005
E26.9 Hyperaldosteronism, unspecified	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
F34.1 Dysthymia	0.000	0.995	0.005
S81.9 Open wound of lower leg, part unspecified	0.000	0.995	0.005
F30 Manic episode	0.000	0.995	0.005
K02.1 Caries of dentin	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.995	0.005
F34.8 Other persistent mood [affective] disorders	0.000	0.995	0.005
E27.2 Addisonian crisis	0.005	0.995	0.000
F39 Unspecified mood [affective] disorder	0.000	0.995	0.005
C18.9 Colon, unspecified	0.005	0.995	0.000
F34.0 Cyclothymia	0.000	0.995	0.004
E29.9 Testicular dysfunction, unspecified	0.004	0.995	0.000
E29.8 Other testicular dysfunction	0.004	0.995	0.000
E29.0 Testicular hyperfunction	0.004	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.995	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.996	0.004
F38.1 Other recurrent mood [affective] disorders	0.000	0.996	0.004
F38.0 Other single mood [affective] disorders	0.000	0.996	0.004
M89.0 Algoneurodystrophy	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
K02.5 Caries with pulp exposure	0.004	0.996	0.000
K02.4 Odontoclasia	0.004	0.996	0.000
K02.3 Arrested dental caries	0.004	0.996	0.000
K02.2 Caries of cementum	0.004	0.996	0.000
K02.0 Caries limited to enamel	0.004	0.996	0.000
K02.8 Other dental caries	0.004	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.004	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.004	0.996	0.000
F30.1 Mania without psychotic symptoms	0.000	0.996	0.004
T18.5 Foreign body in anus and rectum	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
F30.8 Other manic episodes	0.000	0.996	0.004
R20 Disturbances of skin sensation	0.000	0.996	0.004
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
F20.9 Schizophrenia, unspecified	0.004	0.996	0.000
T19 Foreign body in genito-urinary tract	0.004	0.996	0.000
F30.0 Hypomania	0.000	0.996	0.004
F30.9 Manic episode, unspecified	0.000	0.996	0.004
S27 Injury of other and unspecified intrathoracic organs	0.000	0.996	0.004
T19.2 Foreign body in vulva and vagina	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.003	0.996	0.000
F30.2 Mania with psychotic symptoms	0.000	0.996	0.003
E23.0 Hypopituitarism	0.003	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.996	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.003	0.997	0.000
S27.3 Other injuries of lung	0.000	0.997	0.003
T17.2 Foreign body in pharynx	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
F10.0 Acute intoxication	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
R20.3 Hyperaesthesia	0.000	0.997	0.003
G90.2 Horner's syndrome	0.000	0.997	0.003
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
A49.8 Other bacterial infections of unspecified site	0.003	0.997	0.000
T17 Foreign body in respiratory tract	0.003	0.997	0.000
K91.4 Colostomy and enterostomy malfunction	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.003	0.997	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.003	0.997	0.000
T19.3 Foreign body in uterus [any part]	0.003	0.997	0.000
T19.0 Foreign body in urethra	0.003	0.997	0.000
R60.9 Oedema, unspecified	0.000	0.997	0.003
F20 Schizophrenia	0.003	0.997	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.997	0.003
S27.7 Multiple injuries of intrathoracic organs	0.000	0.997	0.003
S27.6 Injury of pleura	0.000	0.997	0.003
S27.5 Injury of thoracic trachea	0.000	0.997	0.003
S27.4 Injury of bronchus	0.000	0.997	0.003
T19.1 Foreign body in bladder	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.997	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.997	0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.003	0.997	0.000
T15.1 Foreign body in conjunctival sac	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.000	0.997	0.003
S27.2 Traumatic heamopneumothorax	0.000	0.997	0.003
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
S27.1 Traumatic haemothorax	0.000	0.997	0.003
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.997	0.003
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.997	0.003
K37 Unspecified appendicitis	0.003	0.997	0.000
B37.9 Candidiasis, unspecified	0.000	0.997	0.003
K91.0 Vomiting following gastro-intestinal surgery	0.003	0.997	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.002	0.997	0.000
S50.9 Superficial injury of forearm, unspecified	0.003	0.997	0.000
K36 Other appendicitis	0.003	0.997	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.003	0.997	0.000
W49.0 Home	0.003	0.997	0.000
R20.1 Hypoaesthesia of skin	0.000	0.997	0.002
H27.1 Dislocation of lens	0.003	0.997	0.000
T15.9 Foreign body on external eye, unspecified	0.002	0.997	0.000
T15.0 Foreign body in cornea	0.002	0.997	0.000
K04.6 Periapical abscess with sinus	0.000	0.997	0.003
T17.4 Foreign body in trachea	0.002	0.997	0.000
T17.1 Foreign body in nostril	0.002	0.997	0.000
T17.0 Foreign body in nasal sinus	0.002	0.997	0.000
W44.0 Home	0.002	0.997	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.997	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
F20.8 Other schizophrenia	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
K04.0 Pulpitis	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
G57.8 Other mononeuropathies of lower limb	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.002
N41.0 Acute prostatitis	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
E65 Localised adiposity	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
R20.0 Anaesthesia of skin	0.000	0.998	0.002
G72.9 Myopathy, unspecified	0.000	0.998	0.002
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
K04.3 Abnormal hard tissue formation in pulp	0.000	0.998	0.002
K04.2 Pulp degeneration	0.000	0.998	0.002
K04.1 Necrosis of pulp	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
T17.3 Foreign body in larynx	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
K04.8 Radicular cyst	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
H52.2 Astigmatism	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
W49 Exposure to other and unspecified inanimate mechanical forces	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
W49.8 Other specified place	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
M25.54 Pain in joint (Hand)	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
M34.9 Systemic sclerosis, unspecified	0.000	0.998	0.002
Z88.5 Personal history of allergy to narcotic agent	0.000	0.998	0.002
C67.5 Bladder neck	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
F43.2 Adjustment disorders	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
W44 Foreign body entering into or through eye or natural orifice	0.002	0.998	0.000
W49.9 Unspecified place	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
J05.1 Acute epiglottitis	0.000	0.998	0.002
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
W49.7 Farm	0.002	0.998	0.000
W49.5 Trade and service area	0.002	0.998	0.000
W49.4 Street and highway	0.002	0.998	0.000
W49.3 Sports and athletics area	0.002	0.998	0.000
W49.2 School, other institution and public administrative area	0.002	0.998	0.000
W49.1 Residential institution	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
H27.8 Other specified disorders of lens	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
W49.6 Industrial and construction area	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
R10.0 Acute abdomen	0.000	0.998	0.002
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.001	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.001	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
W44.9 Unspecified place	0.001	0.998	0.000
W44.5 Trade and service area	0.001	0.998	0.000
W44.8 Other specified place	0.001	0.998	0.000
W44.7 Farm	0.001	0.998	0.000
W44.6 Industrial and construction area	0.001	0.998	0.000
W44.4 Street and highway	0.001	0.998	0.000
W44.3 Sports and athletics area	0.001	0.998	0.000
W44.2 School, other institution and public administrative area	0.001	0.998	0.000
W44.1 Residential institution	0.001	0.998	0.000
H27 Other disorders of lens	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
K29.4 Chronic atrophic gastritis	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
Z90.5 Acquired absence of kidney	0.000	0.998	0.002
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.001
R23.4 Changes in skin texture	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.001
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.001	0.998	0.000
C45.2 Mesothelioma of pericardium	0.000	0.998	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.001
H74.0 Tympanosclerosis	0.000	0.998	0.001
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.999	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.999	0.000
D23.4 Skin of scalp and neck	0.000	0.999	0.001
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.001	0.999	0.000
L73.8 Other specified follicular disorders	0.000	0.999	0.001
V23.5 Passenger injured in traffic accident	0.001	0.999	0.000
G72 Other myopathies	0.000	0.999	0.001
K35-K38 Diseases of appendix	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
L43.8 Other lichen planus	0.000	0.999	0.001
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations