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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12316797
log Bayes Factor = 1.37316
Chromosome 12   position 43,160,744  (GRCh37) Explore rs12316797 on Ensembl!
Variant rs12316797 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M54.57 Low back pain (Lumbosacral region)
0.953 0.047 0.000
M54.5 Low back pain
0.953 0.047 0.000
M54.56 Low back pain (Lumbar region)
0.942 0.058 0.000
M54 Dorsalgia
0.931 0.069 0.000
M54.4 Lumbago with sciatica
0.897 0.103 0.000
M54.1 Radiculopathy
0.873 0.127 0.000
M54.16 Radiculopathy (Lumbar region)
0.851 0.149 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.817 0.183 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.791 0.209 0.000
M54.3 Sciatica
0.788 0.212 0.000
M54.8 Other dorsalgia
0.768 0.232 0.000
M54.59 Low back pain (Site unspecified)
0.750 0.250 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.717 0.283 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.715 0.285 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.695 0.305 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.689 0.311 0.000
M54.54 Low back pain-Thoracic
0.683 0.317 0.000
M54.53 Low back pain-Cervicothoracic
0.683 0.317 0.000
M54.52 Low back pain-Cervical
0.683 0.317 0.000
M54.51 Low back pain-Occipit-atl-axl
0.683 0.317 0.000
M54.0 Panniculitis affecting regions of neck and back
0.667 0.333 0.000
M54.55 Low back pain (Thoracolumbar region)
0.646 0.354 0.000
M54.36 Sciatica (Lumbar region)
0.646 0.354 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.643 0.357 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.643 0.357 0.000
M54.44 Lumbago with sciatica-Thoracic
0.643 0.357 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.643 0.357 0.000
M54.42 Lumbago with sciatica-Cervical
0.643 0.357 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.643 0.357 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.643 0.357 0.000
M54.86 Other dorsalgia (Lumbar region)
0.643 0.357 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.626 0.374 0.000
M54.14 Radiculopathy (Thoracic region)
0.626 0.374 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.626 0.374 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.626 0.374 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.626 0.374 0.000
M54.6 Pain in thoracic spine
0.618 0.381 0.000
M50-M54 Other dorsopathies
0.608 0.392 0.000
M54.19 Radiculopathy (Site unspecified)
0.572 0.428 0.000
M54.39 Sciatica (Site unspecified)
0.569 0.431 0.000
M54.89 Other dorsalgia (Site unspecified)
0.567 0.433 0.000
M54.35 Sciatica (Thoracolumbar region)
0.565 0.435 0.000
M54.34 Sciatica-Thoracic
0.565 0.435 0.000
M54.33 Sciatica-Cervicothoracic
0.565 0.435 0.000
M54.32 Sciatica-Cervical
0.565 0.435 0.000
M54.31 Sciatica-Occipit-atl-axl
0.565 0.435 0.000
M54.30 Sciatica (Multiple sites in spine)
0.565 0.435 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.551 0.449 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.551 0.449 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.551 0.449 0.000
M54.84 Other dorsalgia (Thoracic region)
0.551 0.449 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.551 0.449 0.000
M54.82 Other dorsalgia (Cervical region)
0.551 0.449 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.551 0.449 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.551 0.449 0.000
M50 Cervical disk disorders
0.546 0.454 0.000
M54.12 Radiculopathy (Cervical region)
0.543 0.457 0.000
M50.2 Other cervical disk displacement
0.531 0.469 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.506 0.494 0.000
M53 Other dorsopathies, not elsewhere classified
0.487 0.513 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.478 0.521 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.478 0.521 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.478 0.521 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.478 0.521 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.478 0.521 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.478 0.521 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.478 0.521 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.478 0.521 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.478 0.521 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.478 0.521 0.000
M50.0 Cervical disk disorder with myelopathy
0.453 0.547 0.000
M54.50 Low back pain (Multiple sites in spine)
0.452 0.547 0.000
M54.69 Pain in thoracic spine-Site unspe
0.443 0.556 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.443 0.556 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.443 0.556 0.000
M54.66 Pain in thoracic spine-Lumbar
0.443 0.556 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.443 0.556 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.443 0.556 0.000
M54.62 Pain in thoracic spine-Cervical
0.443 0.556 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.443 0.556 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.443 0.556 0.000
M54.2 Cervicalgia
0.412 0.588 0.000
M53.9 Dorsopathy, unspecified
0.401 0.598 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.394 0.605 0.000
M54.37 Sciatica (Lumbosacral region)
0.393 0.606 0.000
M50.9 Cervical disk disorder, unspecified
0.391 0.609 0.000
M50.8 Other cervical disk disorders
0.391 0.609 0.000
M53.8 Other specified dorsopathies
0.349 0.650 0.000
M53.2 Spinal instabilities
0.349 0.650 0.000
M53.1 Cervicobrachial syndrome
0.349 0.650 0.000
M53.0 Cervicocranial syndrome
0.349 0.650 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.348 0.652 0.000
M54.9 Dorsalgia, unspecified
0.341 0.659 0.000
M53.96 Dorsopathy, unspecified (Lumbar region)
0.340 0.660 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.305 0.695 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.302 0.697 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.296 0.704 0.000
M54.27 Cervicalgia-Lumbosacral
0.296 0.704 0.000
M54.26 Cervicalgia-Lumbar
0.296 0.704 0.000
M54.25 Cervicalgia-Thoracolumbar
0.296 0.704 0.000
M54.24 Cervicalgia-Thoracic
0.296 0.704 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.296 0.704 0.000
M54.20 Cervicalgia-Mult site
0.296 0.704 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.288 0.712 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.288 0.712 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.288 0.712 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.288 0.712 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.288 0.712 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.288 0.712 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.288 0.712 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.288 0.712 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.288 0.712 0.000
M54.29 Cervicalgia-Site unspe
0.282 0.717 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.269 0.731 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.266 0.734 0.000
M45-M49 Spondylopathies
0.262 0.738 0.000
M50.1 Cervical disk disorder with radiculopathy
0.257 0.743 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.251 0.749 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.251 0.749 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.251 0.749 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.251 0.749 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.251 0.749 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.251 0.749 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.251 0.749 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.251 0.749 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.251 0.749 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.251 0.749 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.251 0.749 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.251 0.749 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.251 0.749 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.251 0.749 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.251 0.749 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.251 0.749 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.251 0.749 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.251 0.749 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.251 0.749 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.251 0.749 0.000
M53.29 Spinal instabilities (Site unspecified)
0.251 0.749 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.251 0.749 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.251 0.749 0.000
M53.26 Spinal instabilities (Lumbar region)
0.251 0.749 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.251 0.749 0.000
M53.24 Spinal instabilities (Thoracic region)
0.251 0.749 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.251 0.749 0.000
M53.22 Spinal instabilities (Cervical region)
0.251 0.749 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.251 0.749 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.251 0.749 0.000
M53.89 Other specified dorsopathies (Site unspecified)
0.251 0.749 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.251 0.749 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.251 0.749 0.000
M53.86 Other specified dorsopathies (Lumbar region)
0.251 0.749 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.251 0.749 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.251 0.749 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.251 0.749 0.000
M53.82 Other specified dorsopathies (Cervical region)
0.251 0.749 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.251 0.749 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.251 0.749 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.250 0.750 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.250 0.750 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.250 0.750 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.250 0.750 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.250 0.750 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.250 0.750 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.250 0.750 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.250 0.750 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.246 0.753 0.000
M80-M85 Disorders of bone density and structure
0.246 0.754 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.245 0.755 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.245 0.755 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.245 0.755 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.245 0.755 0.000
M45 Ankylosing spondylitis
0.238 0.762 0.000
M46 Other inflammatory spondylopathies
0.233 0.767 0.000
M65-M68 Disorders of synovium and tendon
0.232 0.768 0.000
M81 Osteoporosis without pathological fracture
0.230 0.770 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.229 0.771 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.223 0.777 0.000
M40-M43 Deforming dorsopathies
0.213 0.786 0.000
M81.9 Osteoporosis, unspecified
0.210 0.790 0.000
M48 Other spondylopathies
0.208 0.792 0.000
M46.4 Discitis, unspecified
0.208 0.792 0.000
M91-M94 Chondropathies
0.207 0.792 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.206 0.794 0.000
M86-M90 Other osteopathies
0.201 0.799 0.000
M49 Spondylopathies in diseases classified elsewhere
0.199 0.801 0.000
M67 Other disorders of synovium and tendon
0.196 0.804 0.000
M85 Other disorders of bone density and structure
0.195 0.805 0.000
M84 Disorders of continuity of bone
0.195 0.805 0.000
M60-M63 Disorders of muscles
0.195 0.805 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.192 0.807 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.190 0.810 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.190 0.810 0.000
M47 Spondylosis
0.189 0.811 0.000
M65 Synovitis and tenosynovitis
0.188 0.812 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.186 0.813 0.000
M00-M03 Infectious arthropathies
0.186 0.814 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.185 0.815 0.000
M41 Scoliosis
0.181 0.819 0.000
M81.4 Drug-induced osteoporosis
0.177 0.823 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.177 0.823 0.000
M83 Adult osteomalacia
0.176 0.823 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.175 0.825 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.173 0.827 0.000
M81.2 Osteoporosis of disuse
0.172 0.828 0.000
M85.8 Other specified disorders of bone density and structure
0.172 0.828 0.000
M47.9 Spondylosis, unspecified
0.171 0.829 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.171 0.829 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.171 0.829 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.171 0.829 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.171 0.829 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.171 0.829 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.171 0.829 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.171 0.829 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.170 0.830 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.167 0.832 0.000
M46.8 Other specified inflammatory spondylopathies
0.167 0.833 0.000
M46.5 Other infective spondylopathies
0.167 0.833 0.000
M46.2 Osteomyelitis of vertebra
0.167 0.833 0.000
M46.0 Spinal enthesopathy
0.167 0.833 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.167 0.833 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.166 0.834 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.166 0.834 0.000
M81.8 Other osteoporosis
0.165 0.835 0.000
M81.6 Localised osteoporosis [Lequesne]
0.165 0.835 0.000
M81.5 Idiopathic osteoporosis
0.165 0.835 0.000
M81.1 Postoophorectomy osteoporosis
0.165 0.835 0.000
M81.0 Postmenopausal osteoporosis
0.165 0.835 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.164 0.836 0.000
M84.0 Malunion of fracture
0.163 0.837 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.163 0.837 0.000
M65.8 Other synovitis and tenosynovitis
0.163 0.837 0.000
M40 Kyphosis and lordosis
0.163 0.837 0.000
M87 Osteonecrosis
0.163 0.837 0.000
M94 Other disorders of cartilage
0.162 0.838 0.000
M66 Spontaneous rupture of synovium and tendon
0.161 0.839 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.159 0.841 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.159 0.841 0.000
M41.9 Scoliosis, unspecified
0.158 0.842 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.156 0.844 0.000
M50.3 Other cervical disk degeneration
0.156 0.844 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.156 0.844 0.000
M67.1 Other contracture of tendon (sheath)
0.156 0.844 0.000
M84.4 Pathological fracture, not elsewhere classified
0.155 0.844 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.154 0.846 0.000
M67.8 Other specified disorders of synovium and tendon
0.154 0.846 0.000
M84.8 Other disorders of continuity of bone
0.154 0.846 0.000
M82 Osteoporosis in diseases classified elsewhere
0.153 0.847 0.000
M42 Spinal osteochondrosis
0.153 0.847 0.000
M86 Osteomyelitis
0.153 0.847 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.152 0.847 0.000
M92 Other juvenile osteochondrosis
0.151 0.849 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.151 0.849 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.151 0.849 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.151 0.849 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.151 0.849 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.151 0.849 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.150 0.850 0.000
M48.9 Spondylopathy, unspecified
0.149 0.851 0.000
M48.8 Other specified spondylopathies
0.149 0.851 0.000
M48.4 Fatigue fracture of vertebra
0.149 0.851 0.000
M48.3 Traumatic spondylopathy
0.149 0.851 0.000
M48.2 Kissing spine
0.149 0.851 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.149 0.851 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.149 0.851 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.149 0.851 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.149 0.851 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.149 0.851 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.149 0.851 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.149 0.851 0.000
M46.42 Discitis, unspecified (Cervical region)
0.149 0.851 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.149 0.851 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.149 0.851 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.149 0.851 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.149 0.851 0.000
M67.0 Short Achilles tendon (acquired)
0.148 0.852 0.000
M80 Osteoporosis with pathological fracture
0.148 0.852 0.000
M51 Other intervertebral disk disorders
0.145 0.855 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.145 0.855 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.145 0.855 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.143 0.857 0.000
M49.4 Neuropathic spondylopathy
0.143 0.857 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.143 0.857 0.000
M49.2 Enterobacterial spondylitis
0.143 0.857 0.000
M49.1 Brucella spondylitis
0.143 0.857 0.000
M49.0 Tuberculosis of spine
0.143 0.857 0.000
M62 Other disorders of muscle
0.143 0.857 0.000
M88 Paget's disease of bone [osteitis deformans]
0.143 0.857 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.142 0.858 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.141 0.859 0.000
M67.3 Transient synovitis
0.141 0.859 0.000
M93 Other osteochondropathies
0.141 0.859 0.000
M85.9 Disorder of bone density and structure, unspecified
0.140 0.860 0.000
M85.5 Aneurysmal bone cyst
0.140 0.860 0.000
M85.4 Solitary bone cyst
0.140 0.860 0.000
M85.3 Osteitis condensans
0.140 0.860 0.000
M85.2 Hyperostosis of skull
0.140 0.860 0.000
M85.1 Skeletal fluorosis
0.140 0.860 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.140 0.860 0.000
M84.9 Disorder of continuity of bone, unspecified
0.140 0.860 0.000
M84.3 Stress fracture, not elsewhere classified
0.140 0.860 0.000
M84.2 Delayed union of fracture
0.140 0.860 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.140 0.860 0.000
M61 Calcification and ossification of muscle
0.140 0.860 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.140 0.860 0.000
M90 Osteopathies in diseases classified elsewhere
0.139 0.861 0.000
M85.6 Other cyst of bone
0.139 0.861 0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.139 0.861 0.000
M60 Myositis
0.138 0.862 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.136 0.864 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.136 0.864 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.136 0.864 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.136 0.864 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.136 0.864 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.136 0.864 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.136 0.864 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.135 0.865 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.135 0.865 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.135 0.865 0.000
M65.2 Calcific tendinitis
0.135 0.865 0.000
M65.0 Abscess of tendon sheath
0.135 0.865 0.000
M67.4 Ganglion
0.135 0.865 0.000
M47.1 Other spondylosis with myelopathy
0.135 0.865 0.000
M65.1 Other infective (teno)synovitis
0.134 0.866 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.134 0.866 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.134 0.866 0.000
M02 Reactive arthropathies
0.134 0.866 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.134 0.866 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.133 0.867 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.133 0.867 0.000
M94.8 Other specified disorders of cartilage
0.132 0.867 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.132 0.868 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.132 0.868 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.131 0.869 0.000
M87.8 Other osteonecrosis
0.131 0.869 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.130 0.870 0.000
M41.5 Other secondary scoliosis
0.130 0.870 0.000
M41.4 Neuromuscular scoliosis
0.130 0.870 0.000
M41.3 Thoracogenic scoliosis
0.130 0.870 0.000
M41.2 Other idiopathic scoliosis
0.130 0.870 0.000
M41.1 Juvenile idiopathic scoliosis
0.130 0.870 0.000
M41.0 Infantile idiopathic scoliosis
0.130 0.870 0.000
M41.8 Other forms of scoliosis
0.129 0.871 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.128 0.871 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.128 0.872 0.000
M84.04 Malunion of fracture (Hand)
0.127 0.872 0.000
M89 Other disorders of bone
0.128 0.872 0.000
M81.48 Drug-induced osteoporosis (Other)
0.127 0.873 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.127 0.873 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.127 0.873 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.127 0.873 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.127 0.873 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.127 0.873 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.127 0.873 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.127 0.873 0.000
M87.9 Osteonecrosis, unspecified
0.127 0.873 0.000
M40.2 Other and unspecified kyphosis
0.127 0.873 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.127 0.873 0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.127 0.873 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.127 0.873 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.127 0.873 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.127 0.873 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.127 0.873 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.127 0.873 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.127 0.873 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.127 0.873 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.127 0.873 0.000
M00 Pyogenic arthritis
0.127 0.873 0.000
M83.9 Adult osteomalacia, unspecified
0.127 0.873 0.000
M83.8 Other adult osteomalacia
0.127 0.873 0.000
M83.5 Other drug-induced osteomalacia in adults
0.127 0.873 0.000
M83.4 Aluminum bone disease
0.127 0.873 0.000
M83.3 Adult osteomalacia due to malnutrition
0.127 0.873 0.000
M83.2 Adult osteomalacia due to malabsorption
0.127 0.873 0.000
M83.1 Senile osteomalacia
0.127 0.873 0.000
M83.0 Puerperal osteomalacia
0.127 0.873 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.126 0.874 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.126 0.874 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.126 0.874 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.126 0.874 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.126 0.874 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.126 0.874 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.126 0.874 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.126 0.874 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.126 0.874 0.000
M43 Other deforming dorsopathies
0.125 0.875 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.125 0.875 0.000
M66.4 Spontaneous rupture of other tendons
0.125 0.875 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.125 0.875 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.124 0.875 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.124 0.876 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.124 0.876 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.124 0.876 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.124 0.876 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.124 0.876 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.124 0.876 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.124 0.876 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.124 0.876 0.000
M81.28 Osteoporosis of disuse (Other)
0.124 0.876 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.124 0.876 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.124 0.876 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.124 0.876 0.000
M81.24 Osteoporosis of disuse (Hand)
0.124 0.876 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.124 0.876 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.124 0.876 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.124 0.876 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.124 0.876 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.124 0.876 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.124 0.876 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.124 0.876 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.124 0.876 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.124 0.876 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.124 0.876 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.124 0.876 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.123 0.877 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.123 0.877 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.123 0.877 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.123 0.877 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.123 0.877 0.000
M84.01 Malunion of fracture (Shoulder region)
0.122 0.878 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.122 0.878 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.122 0.878 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.122 0.878 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.122 0.878 0.000
M51.4 Schmorl's nodes
0.121 0.879 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.121 0.879 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.120 0.880 0.000
M84.02 Malunion of fracture (Upper arm)
0.120 0.880 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.120 0.880 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.120 0.880 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.120 0.880 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.120 0.880 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.120 0.880 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.120 0.880 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.120 0.880 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.120 0.880 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.120 0.880 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.120 0.880 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.120 0.880 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.120 0.880 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.120 0.880 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.120 0.880 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.120 0.880 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.120 0.880 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.120 0.880 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.120 0.880 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.120 0.880 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.120 0.880 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.120 0.880 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.120 0.880 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.120 0.880 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.120 0.880 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.120 0.880 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.120 0.880 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.120 0.880 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.120 0.880 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.120 0.880 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.120 0.880 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.120 0.880 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.120 0.880 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.120 0.880 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.120 0.880 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.120 0.880 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.120 0.880 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.120 0.880 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.120 0.880 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.120 0.880 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.120 0.880 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.120 0.880 0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.120 0.880 0.000
M86.8 Other osteomyelitis
0.119 0.881 0.000
M91.2 Coxa plana
0.119 0.881 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.118 0.881 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.118 0.881 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.118 0.881 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.118 0.881 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.118 0.881 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.118 0.881 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.118 0.881 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.118 0.881 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.118 0.881 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.118 0.881 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.118 0.881 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.118 0.881 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.118 0.881 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.118 0.881 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.118 0.881 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.118 0.881 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.118 0.881 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.118 0.881 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.118 0.881 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.118 0.881 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.118 0.881 0.000
M81.58 Idiopathic osteoporosis (Other)
0.118 0.881 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.118 0.881 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.118 0.881 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.118 0.881 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.118 0.881 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.118 0.881 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.118 0.881 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.118 0.881 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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