TreeWAS – Variant ID: rs12319113

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.087	0.913	0.000
I26 Pulmonary embolism	0.083	0.917	0.000
I27 Other pulmonary heart diseases	0.079	0.921	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.079	0.921	0.000
I27.2 Other secondary pulmonary hypertension	0.079	0.921	0.000
I27.8 Other specified pulmonary heart diseases	0.071	0.929	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.069	0.931	0.000
I28 Other diseases of pulmonary vessels	0.066	0.933	0.000
I27.0 Primary pulmonary hypertension	0.058	0.942	0.000
I28.8 Other specified diseases of pulmonary vessels	0.058	0.942	0.000
I27.1 Kyphoscoliotic heart disease	0.057	0.943	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.048	0.952	0.000
I28.1 Aneurysm of pulmonary artery	0.048	0.952	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.048	0.952	0.000
I27.9 Pulmonary heart disease, unspecified	0.045	0.955	0.000
K76 Other diseases of liver	0.024	0.976	0.000
K76.6 Portal hypertension	0.022	0.977	0.000
K70-K77 Diseases of liver	0.022	0.978	0.000
K76.9 Liver disease, unspecified	0.022	0.978	0.000
K74 Fibrosis and cirrhosis of liver	0.022	0.978	0.000
K74.6 Other and unspecified cirrhosis of liver	0.022	0.978	0.000
K76.8 Other specified diseases of liver	0.020	0.980	0.000
K76.7 Hepatorenal syndrome	0.019	0.981	0.000
K75 Other inflammatory liver diseases	0.018	0.982	0.000
K70 Alcoholic liver disease	0.018	0.982	0.000
K73 Chronic hepatitis, not elsewhere classified	0.018	0.982	0.000
K74.5 Biliary cirrhosis, unspecified	0.018	0.982	0.000
K74.0 Hepatic fibrosis	0.017	0.983	0.000
R94.5 Abnormal results of liver function studies	0.017	0.983	0.000
K76.5 Hepatic veno-occlusive disease	0.017	0.983	0.000
K76.4 Peliosis hepatis	0.017	0.983	0.000
K76.3 Infarction of liver	0.017	0.983	0.000
K76.2 Central haemorrhagic necrosis of liver	0.017	0.983	0.000
K76.1 Chronic passive congestion of liver	0.017	0.983	0.000
R94 Abnormal results of function studies	0.016	0.984	0.000
K70.3 Alcoholic cirrhosis of liver	0.016	0.984	0.000
K77 Liver disorders in diseases classified elsewhere	0.016	0.984	0.000
K71 Toxic liver disease	0.016	0.984	0.000
K74.4 Secondary biliary cirrhosis	0.016	0.984	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.016	0.984	0.000
K74.1 Hepatic sclerosis	0.016	0.984	0.000
K75.8 Other specified inflammatory liver diseases	0.016	0.984	0.000
K70.0 Alcoholic fatty liver	0.016	0.984	0.000
K72 Hepatic failure, not elsewhere classified	0.015	0.985	0.000
K75.4 Autoimmune hepatitis	0.015	0.985	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.015	0.985	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.015	0.985	0.000
K75.9 Inflammatory liver disease, unspecified	0.014	0.986	0.000
K73.9 Chronic hepatitis, unspecified	0.014	0.986	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.014	0.986	0.000
R94.3 Abnormal results of cardiovascular function studies	0.014	0.986	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.014	0.986	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.014	0.986	0.000
K74.3 Primary biliary cirrhosis	0.013	0.986	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.013	0.987	0.000
K75.2 Nonspecific reactive hepatitis	0.013	0.987	0.000
K75.1 Phlebitis of portal vein	0.013	0.987	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.013	0.987	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.013	0.987	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.013	0.987	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.013	0.987	0.000
R94.4 Abnormal results of kidney function studies	0.013	0.987	0.000
R94.6 Abnormal results of thyroid function studies	0.013	0.987	0.000
K72.9 Hepatic failure, unspecified	0.012	0.988	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.012	0.988	0.000
R94.7 Abnormal results of other endocrine function studies	0.012	0.988	0.000
R94.2 Abnormal results of pulmonary function studies	0.012	0.988	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.012	0.988	0.000
R94.0 Abnormal results of function studies of central nervous system	0.012	0.988	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.012	0.988	0.000
K70.9 Alcoholic liver disease, unspecified	0.012	0.988	0.000
K71.9 Toxic liver disease, unspecified	0.012	0.988	0.000
K71.8 Toxic liver disease with other disorders of liver	0.012	0.988	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.012	0.988	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.012	0.988	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.012	0.988	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.012	0.988	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.012	0.988	0.000
K71.2 Toxic liver disease with acute hepatitis	0.012	0.988	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.012	0.988	0.000
K71.0 Toxic liver disease with cholestasis	0.012	0.988	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.012	0.988	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
K70.1 Alcoholic hepatitis	0.012	0.988	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.012	0.988	0.000
K72.1 Chronic hepatic failure	0.011	0.989	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.011	0.989	0.000
K70.4 Alcoholic hepatic failure	0.011	0.989	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.010	0.990	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.010	0.990	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.010	0.990	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.010	0.990	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.010	0.990	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.009	0.990	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.009	0.990	0.000
K72.0 Acute and subacute hepatic failure	0.009	0.991	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.009	0.991	0.000
K75.0 Abscess of liver	0.009	0.991	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.009	0.991	0.000
R90.0 Intracranial space-occupying lesion	0.008	0.992	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.008	0.992	0.000
E14.9 Without complications	0.000	0.992	0.008
R26.8 Other and unspecified abnormalities of gait and mobility	0.007	0.993	0.000
M54.9 Dorsalgia, unspecified	0.007	0.993	0.000
R26 Abnormalities of gait and mobility	0.007	0.993	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.006	0.994	0.000
R26.3 Immobility	0.006	0.994	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
I85.9 Oesophageal varices without bleeding	0.006	0.994	0.000
R26.0 Ataxic gait	0.006	0.994	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.006	0.994	0.000
F05.9 Delirium, unspecified	0.005	0.995	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.005	0.995	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.005	0.995	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.005	0.995	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.005	0.995	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.005	0.995	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.005	0.995	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.005	0.995	0.000
R26.1 Paralytic gait	0.005	0.995	0.000
M23.3 Other meniscus derangements	0.005	0.995	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.004	0.995	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.004	0.995	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
M54.4 Lumbago with sciatica	0.004	0.996	0.000
M23.37 Other meniscus derangements-Capsular lig	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.004	0.996	0.000
C71.3 Parietal lobe	0.004	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.004	0.996	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.996	0.004
C71.2 Temporal lobe	0.003	0.996	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.997	0.003
K13.0 Diseases of lips	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
M54 Dorsalgia	0.003	0.997	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.003	0.997	0.000
E14 Unspecified diabetes mellitus	0.000	0.997	0.003
F05.1 Delirium superimposed on dementia	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
M54.39 Sciatica (Site unspecified)	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.000	0.997	0.003
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.003	0.997	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.44 Lumbago with sciatica-Thoracic	0.003	0.997	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.003	0.997	0.000
M54.42 Lumbago with sciatica-Cervical	0.003	0.997	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.003	0.997	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.003	0.997	0.000
M54.3 Sciatica	0.003	0.997	0.000
F05.8 Other delirium	0.003	0.997	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.997	0.003
M54.6 Pain in thoracic spine	0.003	0.997	0.000
M54.8 Other dorsalgia	0.003	0.997	0.000
M54.0 Panniculitis affecting regions of neck and back	0.003	0.997	0.000
Y86 Sequelae of other accidents	0.003	0.997	0.000
E14.8 With unspecified complications	0.000	0.997	0.003
E14.7 With multiple complications	0.000	0.997	0.003
E14.6 With other specified complications	0.000	0.997	0.003
E14.5 With peripheral circulatory complications	0.000	0.997	0.003
E14.4 With neurological complications	0.000	0.997	0.003
E14.2 Withrenal complications	0.000	0.997	0.003
E14.1 With ketoacidosis	0.000	0.997	0.003
E14.0 With coma	0.000	0.997	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M54.1 Radiculopathy	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.002	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.002	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.002	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.002	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.002	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.002	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.002	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.002	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.002	0.998	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.002	0.998	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.002	0.998	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.002	0.998	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.002	0.998	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.002	0.998	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.002	0.998	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.002	0.998	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.002	0.998	0.000
M54.84 Other dorsalgia (Thoracic region)	0.002	0.998	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.82 Other dorsalgia (Cervical region)	0.002	0.998	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
M54.2 Cervicalgia	0.002	0.998	0.000
I20.8 Other forms of angina pectoris	0.002	0.998	0.000
I08 Multiple valve diseases	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.998	0.002
C69.9 Eye, unspecified	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
C92 Myeloid leukaemia	0.000	0.998	0.002
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
W44.0 Home	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.002	0.998	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.002	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.998	0.000
M54.27 Cervicalgia-Lumbosacral	0.002	0.998	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.998	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.998	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.998	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.20 Cervicalgia-Mult site	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.000	0.998	0.002
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
M54.12 Radiculopathy (Cervical region)	0.002	0.998	0.000
K01.1 Impacted teeth	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.7 Other myeloid leukaemia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.001	0.998	0.000
C70.1 Spinal meninges	0.001	0.998	0.000
C70.0 Cerebral meninges	0.001	0.998	0.000
C72.9 Central nervous system, unspecified	0.001	0.998	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.998	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.998	0.000
C72.4 Acoustic nerve	0.001	0.998	0.000
C72.3 Optic nerve	0.001	0.998	0.000
C72.2 Olfactory nerve	0.001	0.998	0.000
C72.1 Cauda equina	0.001	0.998	0.000
C72.0 Spinal cord	0.001	0.998	0.000
M54.29 Cervicalgia-Site unspe	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
N95.1 Menopausal and female climacteric states	0.000	0.998	0.002
R25.3 Fasciculation	0.002	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
R25.0 Abnormal head movements	0.002	0.998	0.000
I08.8 Other multiple valve diseases	0.000	0.998	0.001
K29.0 Acute haemorrhagic gastritis	0.002	0.998	0.000
N95 Menopausal and other perimenopausal disorders	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.001	0.998	0.000
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.002	0.998	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.002	0.998	0.000
K07.4 Malocclusion, unspecified	0.001	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.001	0.998	0.000
H54.4 Blindness, one eye	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.001	0.998	0.000
K08.3 Retained dental root	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.001
W44 Foreign body entering into or through eye or natural orifice	0.001	0.998	0.000
Y89 Sequelae of other external causes	0.001	0.998	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.001	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.001	0.998	0.000
K07.6 Temporomandibular joint disorders	0.001	0.998	0.000
N95.3 States associated with artificial menopause	0.000	0.998	0.001
Q05.9 Spina bifida, unspecified	0.001	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.001	0.998	0.000
C09.9 Tonsil, unspecified	0.001	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.001	0.998	0.000
W07.0 Home	0.001	0.998	0.000
W13.9 Unspecified place	0.001	0.998	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
Y85 Sequelae of transport accidents	0.001	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
T84.2 Mechanical complication of internal fixation device of other bones	0.001	0.999	0.000
R27 Other lack of coordination	0.001	0.999	0.000
W07 Fall involving chair	0.001	0.999	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.001	0.999	0.000
W14.9 Unspecified place	0.001	0.999	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.999	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.999	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.999	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.999	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.999	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.999	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.999	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.999	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.999	0.000
C90.0 Multiple myeloma	0.000	0.999	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.999	0.001
K07.9 Dentofacial anomaly, unspecified	0.001	0.999	0.000
K07.8 Other dentofacial anomalies	0.001	0.999	0.000
K07.5 Dentofacial functional abnormalities	0.001	0.999	0.000
K07.2 Anomalies of dental arch relationship	0.001	0.999	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.001	0.999	0.000
K07.0 Major anomalies of jaw size	0.001	0.999	0.000
W13 Fall from, out of or through building or structure	0.001	0.999	0.000
N32.9 Bladder disorder, unspecified	0.001	0.999	0.000
S00.3 Superficial injury of nose	0.001	0.999	0.000
W05.0 Home	0.001	0.999	0.000
W14 Fall from tree	0.001	0.999	0.000
S00.8 Superficial injury of other parts of head	0.001	0.999	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.001	0.999	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.001	0.999	0.000
Z45.8 Adjustment and management of other implanted devices	0.001	0.999	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.001	0.999	0.000
D73.0 Hyposplenism	0.001	0.999	0.000
K11.5 Sialolithiasis	0.000	0.999	0.001
W07.9 Unspecified place	0.001	0.999	0.000
W05 Fall involving wheelchair	0.001	0.999	0.000
W00-W19 Falls	0.001	0.999	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.000	0.999	0.001
W44.9 Unspecified place	0.001	0.999	0.000
W44.5 Trade and service area	0.001	0.999	0.000
W44.8 Other specified place	0.001	0.999	0.000
W44.7 Farm	0.001	0.999	0.000
W44.6 Industrial and construction area	0.001	0.999	0.000
W44.4 Street and highway	0.001	0.999	0.000
W44.3 Sports and athletics area	0.001	0.999	0.000
W44.2 School, other institution and public administrative area	0.001	0.999	0.000
W44.1 Residential institution	0.001	0.999	0.000
Y87.2 Sequelae of events of undetermined intent	0.001	0.999	0.000
Y87.1 Sequelae of assault	0.001	0.999	0.000
Y87.0 Sequelae of intentional self-harm	0.001	0.999	0.000
Y89.9 Sequelae of unspecified external cause	0.001	0.999	0.000
Y89.1 Sequelae of war operations	0.001	0.999	0.000
Y89.0 Sequelae of legal intervention	0.001	0.999	0.000
K01 Embedded and impacted teeth	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.999	0.001
T51 Toxic effect of alcohol	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.999	0.001
N18.4 Chronic kidney disease, stage 4	0.000	0.999	0.001
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.001	0.999	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.001	0.999	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.001	0.999	0.000
W60.0 Home	0.001	0.999	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
L50.0 Allergic urticaria	0.001	0.999	0.000
M21.2 Flexion deformity	0.001	0.999	0.000
S00.7 Multiple superficial injuries of head	0.001	0.999	0.000
J84 Other interstitial pulmonary diseases	0.001	0.999	0.000
Y88 Sequelae of surgical and medical care as external cause	0.001	0.999	0.000
K01.0 Embedded teeth	0.001	0.999	0.000
L60.8 Other nail disorders	0.001	0.999	0.000
R27.8 Other and unspecified lack of coordination	0.001	0.999	0.000
W07.2 School, other institution and public administrative area	0.001	0.999	0.000
W07.8 Other specified place	0.001	0.999	0.000
W07.7 Farm	0.001	0.999	0.000
W07.6 Industrial and construction area	0.001	0.999	0.000
W07.5 Trade and service area	0.001	0.999	0.000
W07.4 Street and highway	0.001	0.999	0.000
W07.3 Sports and athletics area	0.001	0.999	0.000
W07.1 Residential institution	0.001	0.999	0.000
O16 Unspecified maternal hypertension	0.001	0.999	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.001	0.999	0.000
W06 Fall involving bed	0.001	0.999	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.001	0.999	0.000
D07.5 Prostate	0.000	0.999	0.001
W13.8 Other specified place	0.001	0.999	0.000
W13.0 Home	0.001	0.999	0.000
W13.7 Farm	0.001	0.999	0.000
W13.6 Industrial and construction area	0.001	0.999	0.000
W13.5 Trade and service area	0.001	0.999	0.000
W13.4 Street and highway	0.001	0.999	0.000
W13.3 Sports and athletics area	0.001	0.999	0.000
W13.2 School, other institution and public administrative area	0.001	0.999	0.000
W13.1 Residential institution	0.001	0.999	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.001	0.999	0.000
Y85.0 Sequelae of motor-vehicle accident	0.001	0.999	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.999	0.001
T79 Certain early complications of trauma, not elsewhere classified	0.001	0.999	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.001	0.999	0.000
M75.0 Adhesive capsulitis of shoulder	0.001	0.999	0.000
W14.8 Other specified place	0.001	0.999	0.000
W14.7 Farm	0.001	0.999	0.000
W14.6 Industrial and construction area	0.001	0.999	0.000
W14.5 Trade and service area	0.001	0.999	0.000
W14.4 Street and highway	0.001	0.999	0.000
W14.3 Sports and athletics area	0.001	0.999	0.000
W14.2 School, other institution and public administrative area	0.001	0.999	0.000
W14.1 Residential institution	0.001	0.999	0.000
W14.0 Home	0.001	0.999	0.000
Y40.3 Macrolides	0.001	0.999	0.000
I38 Endocarditis, valve unspecified	0.001	0.999	0.000
W17 Other fall from one level to another	0.001	0.999	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.999	0.001
M21.1 Varus deformity, not elsewhere classified	0.001	0.999	0.000
M65.3 Trigger finger	0.000	0.999	0.001
W05.9 Unspecified place	0.001	0.999	0.000
W05.8 Other specified place	0.001	0.999	0.000
W05.7 Farm	0.001	0.999	0.000
W05.6 Industrial and construction area	0.001	0.999	0.000
W05.5 Trade and service area	0.001	0.999	0.000
W05.4 Street and highway	0.001	0.999	0.000
W05.3 Sports and athletics area	0.001	0.999	0.000
W05.2 School, other institution and public administrative area	0.001	0.999	0.000
W05.1 Residential institution	0.001	0.999	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.001	0.999	0.000
W15 Fall from cliff	0.001	0.999	0.000
W12 Fall on and from scaffolding	0.001	0.999	0.000
W11 Fall on and from ladder	0.001	0.999	0.000
W09 Fall involving playground equipment	0.001	0.999	0.000
W04 Fall while being carried or supported by other persons	0.001	0.999	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.001	0.999	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.001	0.999	0.000
W00 Fall on same level involving ice and snow	0.001	0.999	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
W44.59 Foreign body entering into or through eye or natural orifice; Trade and service area;During unspecified activity	0.001	0.999	0.000
W44.99 Foreign body entering into or through eye or natural orifice, Unspecified place , During unspecified activity	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
T51.8 Other alcohols	0.001	0.999	0.000
T51.3 Fusel oil	0.001	0.999	0.000
T51.2 2-Propanol	0.001	0.999	0.000
T51.1 Methanol	0.001	0.999	0.000
W06.0 Home	0.001	0.999	0.000
W08 Fall involving other furniture	0.001	0.999	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999	0.000
S32.10 Fracture of sacrum (closed)	0.001	0.999	0.000
G91.9 Hydrocephalus, unspecified	0.001	0.999	0.000
J84.8 Other specified interstitial pulmonary diseases	0.001	0.999	0.000
J84.0 Alveolar and parietoalveolar conditions	0.001	0.999	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
Q23.0 Congenital stenosis of aortic valve	0.000	0.999	0.001
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.001	0.999	0.000
W02.9 Unspecified place	0.001	0.999	0.000
W17.6 Industrial and construction area	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations