TreeWAS – Variant ID: rs12325410

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C77.2 Intra-abdominal lymph nodes	0.021	0.979	0.000
N30.8 Other cystitis	0.014	0.986	0.000
C81.9 Hodgkin's disease, unspecified	0.011	0.989	0.000
C81 Hodgkin's disease	0.010	0.990	0.000
C91 Lymphoid leukaemia	0.010	0.990	0.000
C85.1 B-cell lymphoma, unspecified	0.010	0.990	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.010	0.990	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.010	0.990	0.000
C91.1 Chronic lymphocytic leukaemia	0.010	0.990	0.000
C91.9 Lymphoid leukaemia, unspecified	0.009	0.991	0.000
S00.9 Superficial injury of head, part unspecified	0.000	0.991	0.009
C85.7 Other specified types of non-Hodgkin's lymphoma	0.009	0.991	0.000
C91.5 Adult T-cell leukaemia	0.009	0.991	0.000
C81.1 Nodular sclerosis	0.008	0.992	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.008	0.992	0.000
C93 Monocytic leukaemia	0.008	0.992	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.008	0.992	0.000
C81.0 Lymphocytic predominance	0.008	0.992	0.000
C81.7 Other Hodgkin's disease	0.008	0.992	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.008	0.992	0.000
C81.3 Lymphocytic depletion	0.008	0.992	0.000
C81.2 Mixed cellularity	0.008	0.992	0.000
H40.9 Glaucoma, unspecified	0.008	0.992	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.008	0.992	0.000
C91.7 Other lymphoid leukaemia	0.008	0.992	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.008	0.992	0.000
C91.3 Prolymphocytic leukaemia	0.008	0.992	0.000
C91.2 Subacute lymphocytic leukaemia	0.008	0.992	0.000
C83.3 Large cell (diffuse)	0.007	0.993	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
C94 Other leukaemias of specified cell type	0.007	0.993	0.000
C86 Other specified types of T/NK-cell lymphoma	0.007	0.993	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.007	0.993	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.007	0.993	0.000
C85.0 Lymphosarcoma	0.007	0.993	0.000
C91.0 Acute lymphoblastic leukaemia	0.007	0.993	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.993	0.007
C82.2 Large cell, follicular	0.007	0.993	0.000
C95 Leukaemia of unspecified cell type	0.007	0.993	0.000
C93.1 Chronic monocytic leukaemia	0.007	0.993	0.000
C91.4 Hairy-cell leukaemia	0.006	0.993	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.006	0.993	0.000
C88 Malignant immunoproliferative diseases	0.006	0.993	0.000
C92 Myeloid leukaemia	0.006	0.994	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.006	0.994	0.000
C82.3 Follicular lymphoma grade IIIa	0.006	0.994	0.000
M54.36 Sciatica (Lumbar region)	0.006	0.994	0.000
C83.7 Burkitt's tumour	0.006	0.994	0.000
D70 Agranulocytosis	0.006	0.994	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.006	0.994	0.000
C83.6 Undifferentiated (diffuse)	0.006	0.994	0.000
C83.5 Lymphoblastic (diffuse)	0.006	0.994	0.000
C83.4 Immunoblastic (diffuse)	0.006	0.994	0.000
C83.2 Mixed small and large cell (diffuse)	0.006	0.994	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.006	0.994	0.000
G35 Multiple sclerosis	0.000	0.994	0.006
D73.0 Hyposplenism	0.006	0.994	0.000
C93.9 Monocytic leukaemia, unspecified	0.006	0.994	0.000
C93.7 Other monocytic leukaemia	0.006	0.994	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.006	0.994	0.000
C93.2 Subacute monocytic leukaemia	0.006	0.994	0.000
C93.0 Acute monocytic leukaemia	0.006	0.994	0.000
C82.6 Cutaneous follicle centre lymphoma	0.006	0.994	0.000
C82.5 Diffuse follicle centre lymphoma	0.006	0.994	0.000
C82.4 Follicular lymphoma grade IIIb	0.006	0.994	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.006	0.994	0.000
C83.0 Small cell (diffuse)	0.006	0.994	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.005	0.994	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.005	0.994	0.000
C86.4 Blastic NK-cell lymphoma	0.005	0.994	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.005	0.994	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.005	0.994	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.005	0.994	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.005	0.994	0.000
C94.7 Other specified leukaemias	0.005	0.994	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.005	0.994	0.000
C94.5 Acute myelofibrosis	0.005	0.994	0.000
C94.4 Acute panmyelosis	0.005	0.994	0.000
C94.3 Mast cell leukaemia	0.005	0.994	0.000
C94.2 Acute megakaryoblastic leukaemia	0.005	0.994	0.000
C94.1 Chronic erythraemia	0.005	0.994	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.005	0.994	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.994	0.000
C96.8 Histiocytic sarcoma	0.005	0.994	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.994	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.005	0.994	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.005	0.994	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.005	0.994	0.000
C96.3 True histiocytic lymphoma	0.005	0.994	0.000
C96.2 Malignant mast cell tumour	0.005	0.994	0.000
C96.1 Malignant histiocytosis	0.005	0.994	0.000
C96.0 Letterer-Siwe disease	0.005	0.994	0.000
D73 Diseases of spleen	0.006	0.994	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.005	0.994	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
C92.7 Other myeloid leukaemia	0.005	0.995	0.000
C82.0 Small cleaved cell, follicular	0.005	0.995	0.000
C95.7 Other leukaemia of unspecified cell type	0.005	0.995	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.005	0.995	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.005	0.995	0.000
C95.0 Acute leukaemia of unspecified cell type	0.005	0.995	0.000
H40.1 Primary open-angle glaucoma	0.005	0.995	0.000
H40 Glaucoma	0.005	0.995	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.005	0.995	0.000
C88.7 Other malignant immunoproliferative diseases	0.005	0.995	0.000
C88.3 Immunoproliferative small intestinal disease	0.005	0.995	0.000
C88.2 Gamma heavy chain disease	0.005	0.995	0.000
C88.1 Alpha heavy chain disease	0.005	0.995	0.000
C90.1 Plasma cell leukaemia	0.005	0.995	0.000
C90.3 Solitary plasmacytoma	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.005	0.995	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.005	0.995	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.005	0.995	0.000
C92.5 Acute myelomonocytic leukaemia	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.005	0.995	0.000
C92.3 Myeloid sarcoma	0.005	0.995	0.000
C92.2 Subacute myeloid leukaemia	0.005	0.995	0.000
C83.1 Small cleaved cell (diffuse)	0.005	0.995	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.005	0.995	0.000
H54.7 Unspecified visual loss	0.000	0.995	0.005
C84.9 Mature T/NK-cell lymphoma, unspecified	0.004	0.995	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.004	0.995	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.004	0.995	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.004	0.995	0.000
C84.3 Lymphoepithelioid lymphoma	0.004	0.995	0.000
C84.2 T-zone lymphoma	0.004	0.995	0.000
C84.1 Sezary's diease	0.004	0.995	0.000
C84.0 Mycosis fungoides	0.004	0.995	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.004	0.995	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.004	0.995	0.000
D72 Other disorders of white blood cells	0.005	0.995	0.000
C95.9 Leukaemia, unspecified	0.004	0.995	0.000
C92.1 Chronic myeloid leukaemia	0.004	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.004	0.995	0.000
D73.1 Hypersplenism	0.004	0.995	0.000
C84.4 Peripheral T-cell lymphoma	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
D73.3 Abscess of spleen	0.004	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.996	0.000
C90.0 Multiple myeloma	0.004	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D74 Methaemoglobinaemia	0.004	0.996	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.004	0.996	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.004	0.996	0.000
H40.0 Glaucoma suspect	0.004	0.996	0.000
H40.3 Glaucoma secondary to eye trauma	0.004	0.996	0.000
D73.5 Infarction of spleen	0.004	0.996	0.000
H40.6 Glaucoma secondary to drugs	0.004	0.996	0.000
D72.8 Other specified disorders of white blood cells	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.004	0.996	0.000
H40.2 Primary angle-closure glaucoma	0.004	0.996	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.004	0.996	0.000
D33.3 Cranial nerves	0.004	0.996	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.996	0.000
K14.8 Other diseases of tongue	0.004	0.996	0.000
C92.0 Acute myeloid leukaemia	0.004	0.996	0.000
H40.4 Glaucoma secondary to eye inflammation	0.003	0.996	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
D72.1 Eosinophilia	0.003	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
F02.3 Dementia in Parkinson's disease	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.003	0.997	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.997	0.000
D74.8 Other methaemoglobinaemias	0.003	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.997	0.000
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
F02.0 Dementia in Pick's disease	0.003	0.997	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.003	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.003	0.997	0.000
N85.0 Endometrial glandular hyperplasia	0.003	0.997	0.000
H40.5 Glaucoma secondary to other eye disorders	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.003	0.997	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.003	0.997	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.003	0.997	0.000
H40.8 Other glaucoma	0.003	0.997	0.000
H54 Blindness and low vision	0.000	0.997	0.003
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.997	0.003
K14.0 Glossitis	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.003	0.997	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.003	0.997	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.997	0.003
H53.4 Visual field defects	0.000	0.997	0.003
Z86.1 Personal history of infectious and parasitic diseases	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
N90.6 Hypertrophy of vulva	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
H53 Visual disturbances	0.000	0.997	0.003
M66 Spontaneous rupture of synovium and tendon	0.003	0.997	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.997	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.997	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.997	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.997	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.997	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.997	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.997	0.000
K14 Diseases of tongue	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M66.3 Spontaneous rupture of flexor tendons	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
K81.9 Cholecystitis, unspecified	0.003	0.997	0.000
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
D76.3 Other histiocytosis syndromes	0.002	0.997	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.997	0.000
K75.4 Autoimmune hepatitis	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
J93.9 Pneumothorax, unspecified	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.997	0.000
F02.2 Dementia in Huntington's disease	0.002	0.997	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.002
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.998	0.002
M48.06 Spinal stenosis (Lumbar region)	0.000	0.998	0.002
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.002	0.998	0.000
H53.2 Diplopia	0.000	0.998	0.002
H54.5 Low vision, one eye	0.000	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.002
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.002
H54.2 Low vision, both eyes	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
D50-D53 Nutritional anaemias	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
H40-H42 Glaucoma	0.002	0.998	0.000
H53.6 Night blindness	0.000	0.998	0.002
H53.5 Colour vision deficiencies	0.000	0.998	0.002
H53.3 Other disorders of binocular vision	0.000	0.998	0.002
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
M66.1 Rupture of synovium	0.002	0.998	0.000
K14.5 Plicated tongue	0.002	0.998	0.000
K14.4 Atrophy of tongue papillae	0.002	0.998	0.000
K14.3 Hypertrophy of tongue papillae	0.002	0.998	0.000
K14.2 Median rhomboid glossitis	0.002	0.998	0.000
K14.1 Geographic tongue	0.002	0.998	0.000
D53 Other nutritional anaemias	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.002	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.002	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.002	0.998	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.002	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.002	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.002	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.998	0.000
D51.2 Transcobalamin II deficiency	0.002	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.998	0.000
R39.1 Other difficulties with micturition	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.002
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.998	0.002
N90.1 Moderate vulvar dysplasia	0.000	0.998	0.002
N90.0 Mild vulvar dysplasia	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
D56 Thalassaemia	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
K85 Acute pancreatitis	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.000	0.998	0.002
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.998	0.002
N90.3 Dysplasia of vulva, unspecified	0.000	0.998	0.002
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.002
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
D50 Iron deficiency anaemia	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
H53.8 Other visual disturbances	0.000	0.998	0.002
K83.0 Cholangitis	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
B25 Cytomegaloviral disease	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.002	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.002	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.002	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.002	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.002	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.002	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.002	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.002	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.002	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.002
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
H42 Glaucoma in diseases classified elsewhere	0.002	0.998	0.000
M66.19 Rupture of synovium (Site unspecified)	0.002	0.998	0.000
M66.18 Rupture of synovium (Other)	0.002	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.002	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.002	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.002	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.002	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.002	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.002	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.002	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.002	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.002	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.002	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.002	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.002	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.002	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.002	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.002	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.002	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.002	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.998	0.002
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
B25.0 Cytomegaloviral pneumonitis	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.998	0.002
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
B25.8 Other cytomegaloviral diseases	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.002	0.998	0.000
F09 Unspecified organic or symptomatic mental disorder	0.002	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
L89.3 Stage IV decubitus ulcer	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.998	0.000
D50.1 Sideropenic dysphagia	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.001	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
B25.2 Cytomegaloviral pancreatitis	0.001	0.998	0.000
B25.1 Cytomegaloviral hepatitis	0.001	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S12.91 Fracture of neck, part unspecified (open)	0.001	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.001	0.998	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.001	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.001	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
S51.0 Open wound of elbow	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
L89 Decubitus ulcer	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
F07.2 Postconcussional syndrome	0.001	0.998	0.000
L89.2 Stage III decubitus ulcer	0.002	0.998	0.000
D52 Folate deficiency anaemia	0.001	0.998	0.000
M67.43 Ganglion, wrist	0.001	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.001	0.998	0.000
M67.3 Transient synovitis	0.001	0.998	0.000
S05.7 Avulsion of eye	0.001	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.001	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.001	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.001	0.998	0.000
F01 Vascular dementia	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations