TreeWAS – Variant ID: rs12368653

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R63.4 Abnormal weight loss	0.081	0.919	0.000
R63 Symptoms and signs concerning food and fluid intake	0.052	0.948	0.000
R63.0 Anorexia	0.050	0.950	0.000
R63.1 Polydipsia	0.043	0.957	0.000
R63.6 Insufficient intake of food and water due to self neglect	0.041	0.959	0.000
R63.2 Polyphagia	0.038	0.962	0.000
R63.5 Abnormal weight gain	0.033	0.967	0.000
R63.3 Feeding difficulties and mismanagement	0.027	0.973	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.027	0.973	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.021	0.979	0.000
D03.5 Melanoma in situ of trunk	0.014	0.986	0.000
D03 Melanoma in situ	0.013	0.987	0.000
D03.8 Melanoma in situ of other sites	0.010	0.990	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.010	0.990	0.000
S42.20 Fracture of upper end of humerus (closed)	0.010	0.990	0.000
D03.9 Melanoma in situ, unspecified	0.010	0.990	0.000
D03.0 Melanoma in situ of lip	0.010	0.990	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.009	0.991	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.009	0.991	0.000
D03.4 Melanoma in situ of scalp and neck	0.009	0.991	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.007	0.993	0.000
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.994	0.006
Q61.3 Polycystic kidney, unspecified	0.005	0.995	0.000
K37 Unspecified appendicitis	0.000	0.995	0.005
Q61 Cystic kidney disease	0.005	0.995	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.995	0.005
M24.07 Loose body in joint (Ankle and foot)	0.005	0.995	0.000
S42.2 Fracture of upper end of humerus	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.005	0.995	0.000
D48.6 Breast	0.004	0.996	0.000
T42.4 Benzodiazepines	0.004	0.996	0.000
K38.1 Appendicular concretions	0.000	0.996	0.004
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
Q61.4 Renal dysplasia	0.004	0.996	0.000
K38 Other diseases of appendix	0.000	0.996	0.004
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
M24.0 Loose body in joint	0.004	0.996	0.000
K38.9 Disease of appendix, unspecified	0.000	0.996	0.004
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.996	0.004
M07.3 Other psoriatic arthropathies	0.004	0.996	0.000
K38.8 Other specified diseases of appendix	0.000	0.996	0.004
S42.21 Fracture of upper end of humerus (open)	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
K22.4 Dyskinesia of oesophagus	0.004	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.996	0.000
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.996	0.004
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
E87.0 Hyperosmolality and hypernatraemia	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
N23 Unspecified renal colic	0.003	0.997	0.000
K38.3 Fistula of appendix	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
K38.0 Hyperplasia of appendix	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.003	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.003	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.003	0.997	0.000
K38.2 Diverticulum of appendix	0.000	0.997	0.003
K35-K38 Diseases of appendix	0.000	0.997	0.003
M07.38 Other psoriatic arthropathies (Other)	0.003	0.997	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
D10.1 Tongue	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.000	0.997	0.003
D12.3 Transverse colon	0.003	0.997	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
I51.8 Other ill-defined heart diseases	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
M94.8 Other specified disorders of cartilage	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.003	0.997	0.000
H83.0 Labyrinthitis	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M50.2 Other cervical disk displacement	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.997	0.000
E85.8 Other amyloidosis	0.002	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.997	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.000	0.998	0.002
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.002
G50.0 Trigeminal neuralgia	0.000	0.998	0.002
Y83.9 Surgical procedure, unspecified	0.002	0.998	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
S92.1 Fracture of talus	0.000	0.998	0.002
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
K36 Other appendicitis	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
W19.4 Street and highway	0.000	0.998	0.002
T11.1 Open wound of upper limb, level unspecified	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
X23.0 Home	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
M94 Other disorders of cartilage	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.002	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
X23.8 Other specified place	0.002	0.998	0.000
C50.8 Overlapping lesion of breast	0.000	0.998	0.002
E87.2 Acidosis	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
X23.9 Unspecified place	0.002	0.998	0.000
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.002	0.998	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.002	0.998	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.002	0.998	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.002	0.998	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.002	0.998	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.002	0.998	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.002	0.998	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Z54.0 Convalescence following surgery	0.000	0.998	0.002
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.002	0.998	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.002	0.998	0.000
K76.6 Portal hypertension	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
K76 Other diseases of liver	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.002
Z32.0 Pregnancy, not (yet) confirmed	0.002	0.998	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
O30.0 Twin pregnancy	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
T11 Other injuries of upper limb, level unspecified	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.001	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.001	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.001	0.998	0.000
Q64.0 Epispadias	0.001	0.998	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.001	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
E83.8 Other disorders of mineral metabolism	0.002	0.998	0.000
E83.2 Disorders of zinc metabolism	0.002	0.998	0.000
E83.0 Disorders of copper metabolism	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
L90.0 Lichen sclerosus et atrophicus	0.002	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.000	0.998	0.002
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.001
B37.8 Candidiasis of other sites	0.002	0.998	0.000
E27.2 Addisonian crisis	0.000	0.998	0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.001	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.998	0.000
T50.5 Appetite depressants	0.001	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
X23.7 Farm	0.001	0.998	0.000
X23.6 Industrial and construction area	0.001	0.998	0.000
X23.5 Trade and service area	0.001	0.998	0.000
X23.4 Street and highway	0.001	0.998	0.000
X23.3 Sports and athletics area	0.001	0.998	0.000
X23.2 School, other institution and public administrative area	0.001	0.998	0.000
X23.1 Residential institution	0.001	0.998	0.000
K76.7 Hepatorenal syndrome	0.001	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.001	0.998	0.000
K76.4 Peliosis hepatis	0.001	0.998	0.000
K76.3 Infarction of liver	0.001	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.001	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.001	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.001	0.998	0.000
M07.2 Psoriatic spondylitis	0.001	0.998	0.000
M07.1 Arthritis mutilans	0.001	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.001	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
E70 Disorders of aromatic amino-acid metabolism	0.001	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.001
C09.9 Tonsil, unspecified	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
E70.3 Albinism	0.001	0.998	0.000
E73.8 Other lactose intolerance	0.001	0.998	0.000
E73.1 Secondary lactase deficiency	0.001	0.998	0.000
E73.0 Congenital lactase deficiency	0.001	0.998	0.000
E87.4 Mixed disorder of acid-base balance	0.001	0.998	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.001	0.998	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.001	0.998	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.001	0.998	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.001	0.998	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.001	0.998	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.001	0.998	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.001	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.001	0.998	0.000
M24.54 Contracture of joint (Hand)	0.001	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
H06.2 Dysthyroid exophthalmos	0.001	0.998	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.998	0.001
M07.6 Other enteropathic arthropathies	0.001	0.998	0.000
Q52.5 Fusion of labia	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.001	0.998	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.001	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.001	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.001	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.001	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.001	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.001	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.001	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.001	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.001	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.001	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.001	0.998	0.000
M94.38 Chondrolysis (Other)	0.001	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.001	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.001	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.001	0.998	0.000
M94.34 Chondrolysis (Hand)	0.001	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.001	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.001	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.001	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.001	0.998	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.001	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.001	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.001	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.001	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.998	0.001
Q25.1 Coarctation of aorta	0.001	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.001	0.998	0.000
T14.1 Open wound of unspecified body region	0.001	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
E27 Other disorders of adrenal gland	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.999	0.001
E80.1 Porphyria cutanea tarda	0.001	0.999	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
S92.5 Fracture of other toe	0.000	0.999	0.001
T79.9 Unspecified early complication of trauma	0.001	0.999	0.000
T79.1 Fat embolism (traumatic)	0.001	0.999	0.000
T79.0 Air embolism (traumatic)	0.001	0.999	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.001	0.999	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.001	0.999	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.001	0.999	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.001	0.999	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.001	0.999	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.001	0.999	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.001	0.999	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.001	0.999	0.000
C54.9 Corpus uteri, unspecified	0.001	0.999	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.001	0.999	0.000
G61 Inflammatory polyneuropathy	0.000	0.999	0.001
Q65 Congenital deformities of hip	0.001	0.999	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.001	0.999	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.999	0.000
N64.5 Other signs and symptoms in breast	0.001	0.999	0.000
Q24.0 Dextrocardia	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.999	0.001
Q63 Other congenital malformations of kidney	0.001	0.999	0.000
M13.0 Polyarthritis, unspecified	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.001	0.999	0.000
T38.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
T38.7 Androgens and anabolic congeners	0.001	0.999	0.000
T38.5 Other oestrogens and progestogens	0.001	0.999	0.000
T38.4 Oral contraceptives	0.001	0.999	0.000
T38.2 Antithyroid drugs	0.001	0.999	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.999	0.000
E77 Disorders of glycoprotein metabolism	0.001	0.999	0.000
E76 Disorders of glycosaminoglycan metabolism	0.001	0.999	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.999	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.999	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.999	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
B37.9 Candidiasis, unspecified	0.001	0.999	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.001	0.999	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.001	0.999	0.000
E79.1 Lesch-Nyhan syndrome	0.001	0.999	0.000
E80.2 Other porphyria	0.001	0.999	0.000
M94.2 Chondromalacia	0.001	0.999	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
T48.5 Anti-common-cold drugs	0.001	0.999	0.000
T79.4 Traumatic shock	0.001	0.999	0.000
Z36.9 Antenatal screening, unspecified	0.001	0.999	0.000
E84 Cystic fibrosis	0.001	0.999	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.001	0.999	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.001	0.999	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.001	0.999	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.001	0.999	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.001	0.999	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.001	0.999	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.001	0.999	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.001	0.999	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.001	0.999	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.001	0.999	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.001	0.999	0.000
M07.18 Arthritis mutilans (Other)	0.001	0.999	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.001	0.999	0.000
M07.16 Arthritis mutilans (Lower leg)	0.001	0.999	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.001	0.999	0.000
M07.14 Arthritis mutilans (Hand)	0.001	0.999	0.000
M07.13 Arthritis mutilans (Forearm)	0.001	0.999	0.000
M07.12 Arthritis mutilans (Upper arm)	0.001	0.999	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.001	0.999	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.001	0.999	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.001	0.999	0.000
M07.28 Psoriatic spondylitis (Other)	0.001	0.999	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.001	0.999	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.001	0.999	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.001	0.999	0.000
M07.24 Psoriatic spondylitis (Hand)	0.001	0.999	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.001	0.999	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.001	0.999	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.001	0.999	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.001	0.999	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.001	0.999	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.001	0.999	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations