TreeWAS – Variant ID: rs12370275

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.953	0.047
I71 Aortic aneurysm and dissection	0.000	0.958	0.042
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.962	0.038
C25.9 Pancreas, unspecified	0.000	0.964	0.036
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.964	0.036
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.967	0.033
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.968	0.032
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.969	0.030
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.970	0.030
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.970	0.030
I71.0 Dissection of aorta [any part]	0.000	0.972	0.028
C73 Malignant neoplasm of thyroid gland	0.021	0.979	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.017	0.983	0.000
C25 Malignant neoplasm of pancreas	0.000	0.984	0.016
M81.99 Osteoporosis, unspecified (Site unspecified)	0.016	0.984	0.000
C25.2 Tail of pancreas	0.000	0.986	0.014
C25.0 Head of pancreas	0.000	0.987	0.013
C25.3 Pancreatic duct	0.000	0.988	0.012
C25.8 Overlapping lesion of pancreas	0.000	0.988	0.012
C25.7 Other parts of pancreas	0.000	0.988	0.012
M81.90 Osteoporosis, unspecified (Multiple sites)	0.010	0.990	0.000
C25.4 Endocrine pancreas	0.000	0.990	0.010
M81.9 Osteoporosis, unspecified	0.009	0.991	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.991	0.009
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.008	0.992	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.992	0.008
C25.1 Body of pancreas	0.000	0.992	0.007
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.993	0.007
I72 Other aneurysm	0.000	0.993	0.007
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.993	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.007	0.993	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.007	0.993	0.000
I72.9 Aneurysm of unspecified site	0.000	0.993	0.007
I72.3 Aneurysm of iliac artery	0.000	0.993	0.007
C74 Malignant neoplasm of adrenal gland	0.006	0.993	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.006	0.994	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.006	0.994	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.994	0.006
R59.1 Generalised enlarged lymph nodes	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.995	0.005
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.995	0.005
I72.1 Aneurysm of artery of upper extremity	0.000	0.995	0.005
I72.4 Aneurysm of artery of lower extremity	0.000	0.995	0.005
I77 Other disorders of arteries and arterioles	0.000	0.995	0.005
I72.0 Aneurysm of carotid artery	0.000	0.995	0.005
I72.8 Aneurysm of other specified arteries	0.000	0.995	0.005
I78 Diseases of capillaries	0.000	0.995	0.005
C74.9 Adrenal gland, unspecified	0.005	0.995	0.000
I77.6 Arteritis, unspecified	0.000	0.995	0.005
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.995	0.005
C74.1 Medulla of adrenal gland	0.005	0.995	0.000
C74.0 Cortex of adrenal gland	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.000	0.995	0.005
I77.8 Other specified disorders of arteries and arterioles	0.000	0.995	0.005
H40.0 Glaucoma suspect	0.005	0.995	0.000
C75.8 Pluriglandular involvement, unspecified	0.004	0.995	0.000
C75.5 Aortic body and other paraganglia	0.004	0.995	0.000
C75.4 Carotid body	0.004	0.995	0.000
C75.3 Pineal gland	0.004	0.995	0.000
C75.2 Craniopharyngeal duct	0.004	0.995	0.000
C75.0 Parathyroid gland	0.004	0.995	0.000
C75.1 Pituitary gland	0.004	0.996	0.000
I78.8 Other diseases of capillaries	0.000	0.996	0.004
I74.8 Embolism and thrombosis of other arteries	0.000	0.996	0.004
K70.3 Alcoholic cirrhosis of liver	0.000	0.996	0.004
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
C75.9 Endocrine gland, unspecified	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.996	0.004
I72.2 Aneurysm of renal artery	0.000	0.996	0.004
I77.5 Necrosis of artery	0.000	0.996	0.004
I77.4 Coeliac artery compression syndrome	0.000	0.996	0.004
I77.3 Arterial fibromuscular dysplasia	0.000	0.996	0.004
I77.2 Rupture of artery	0.000	0.996	0.004
I78.9 Disease of capillaries, unspecified	0.000	0.996	0.004
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
Q61.0 Congenital single renal cyst	0.000	0.996	0.004
Q76.0 Spina bifida occulta	0.004	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.000	0.996	0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.996	0.004
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
K70 Alcoholic liver disease	0.000	0.996	0.004
K70.9 Alcoholic liver disease, unspecified	0.000	0.996	0.004
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.996	0.004
I70 Atherosclerosis	0.000	0.996	0.004
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
N48.2 Other inflammatory disorders of penis	0.004	0.996	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.996	0.004
Q76 Congenital malformations of spine and bony thorax	0.003	0.996	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.003	0.997	0.000
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
M93.9 Osteochondropathy, unspecified	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.000	0.997	0.003
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
Q76.5 Cervical rib	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.003
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
N18.4 Chronic kidney disease, stage 4	0.003	0.997	0.000
K58 Irritable bowel syndrome	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.003
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.88 Other osteoporosis (Other)	0.002	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
M84 Disorders of continuity of bone	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.997	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.997	0.000
M54.2 Cervicalgia	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.002	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.002	0.997	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.997	0.000
R59.0 Localised enlarged lymph nodes	0.003	0.997	0.000
I73 Other peripheral vascular diseases	0.000	0.997	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.998	0.002
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
Q61 Cystic kidney disease	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
V89.9 Person injured in unspecified vehicle accident	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
R59 Enlarged lymph nodes	0.002	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.002
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.998	0.002
M54.27 Cervicalgia-Lumbosacral	0.000	0.998	0.002
M54.26 Cervicalgia-Lumbar	0.000	0.998	0.002
M54.25 Cervicalgia-Thoracolumbar	0.000	0.998	0.002
M54.24 Cervicalgia-Thoracic	0.000	0.998	0.002
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.20 Cervicalgia-Mult site	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
V89.3 Person injured in unspecified nonmotor-vehicle accident, traffic	0.002	0.998	0.000
V89.1 Person injured in unspecified nonmotor-vehicle accident, nontraffic	0.002	0.998	0.000
V89.0 Person injured in unspecified motor-vehicle accident, nontraffic	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
M83.12 Senile osteomalacia (Upper arm)	0.002	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
X51.9 Unspecified place	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
R52.9 Pain, unspecified	0.002	0.998	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M93 Other osteochondropathies	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.002	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.002	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.002	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.002	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.002	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
R76.0 Raised antibody titer	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
M83.19 Senile osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.002	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.002	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.002	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.002	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
M93.1 Kienbock's disease of adults	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.001	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.998	0.002
M54.29 Cervicalgia-Site unspe	0.000	0.998	0.002
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations