TreeWAS – Variant ID: rs12373805

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83.0 Cholangitis	0.000	0.943	0.057
L84 Corns and callosities	0.016	0.984	0.000
I07.1 Tricuspid insufficiency	0.000	0.984	0.016
R25.2 Cramp and spasm	0.014	0.986	0.000
R25 Abnormal involuntary movements	0.011	0.989	0.000
R25.3 Fasciculation	0.010	0.990	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.009	0.991	0.000
R25.0 Abnormal head movements	0.008	0.992	0.000
R25.1 Tremor, unspecified	0.007	0.993	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.993	0.007
R26 Abnormalities of gait and mobility	0.007	0.993	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.007	0.993	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.993	0.007
R26.2 Difficulty in walking, not elsewhere classified	0.007	0.993	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.007	0.993	0.000
R27 Other lack of coordination	0.006	0.994	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.994	0.006
E66.8 Other obesity	0.006	0.994	0.000
R26.0 Ataxic gait	0.006	0.994	0.000
Z87.0 Personal history of diseases of the respiratory system	0.006	0.994	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.994	0.005
I07.8 Other tricuspid valve diseases	0.000	0.994	0.005
I07.2 Tricuspid stenosis with insufficiency	0.000	0.994	0.005
I07.0 Tricuspid stenosis	0.000	0.994	0.005
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.994	0.006
R26.1 Paralytic gait	0.005	0.995	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.005	0.995	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.005	0.995	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
R27.0 Ataxia, unspecified	0.005	0.995	0.000
R27.8 Other and unspecified lack of coordination	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
C15.5 Lower third of oesophagus	0.005	0.995	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.005	0.995	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.004	0.995	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.004	0.996	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
N32.9 Bladder disorder, unspecified	0.004	0.996	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
R26.3 Immobility	0.004	0.996	0.000
U80.1 Methicillin resistant agent	0.000	0.996	0.004
C15 Malignant neoplasm of oesophagus	0.004	0.996	0.000
K83 Other diseases of biliary tract	0.000	0.996	0.004
Y44.2 Anticoagulants	0.004	0.996	0.000
C44.4 Skin of scalp and neck	0.000	0.996	0.004
C15.3 Upper third of oesophagus	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Z04.8 Examination and observation for other specified reasons	0.004	0.996	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.004	0.996	0.000
C15.9 Oesophagus, unspecified	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.004	0.996	0.000
N97.9 Female infertility, unspecified	0.004	0.996	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
F20.9 Schizophrenia, unspecified	0.000	0.996	0.004
D25.0 Submucous leiomyoma of uterus	0.004	0.996	0.000
F20 Schizophrenia	0.000	0.996	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.997	0.003
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
E66 Obesity	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
S42.0 Fracture of clavicle	0.000	0.997	0.003
K83.5 Biliary cyst	0.000	0.997	0.003
C15.4 Middle third of oesophagus	0.003	0.997	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.997	0.003
F25 Schizoaffective disorders	0.000	0.997	0.003
F20.2 Catatonic schizophrenia	0.000	0.997	0.003
C44 Other malignant neoplasms of skin	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
K83.3 Fistula of bile duct	0.000	0.997	0.003
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
R29.1 Meningismus	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
R41.3 Other amnesia	0.000	0.997	0.003
S51.0 Open wound of elbow	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
K83.2 Perforation of bile duct	0.000	0.997	0.003
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.000	0.997	0.003
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
F25.2 Schizoaffective disorder, mixed type	0.000	0.997	0.003
K83.9 Disease of biliary tract, unspecified	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
R29.0 Tetany	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.997	0.003
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
F20.8 Other schizophrenia	0.000	0.997	0.003
C18.2 Ascending colon	0.000	0.997	0.003
F20.5 Residual schizophrenia	0.000	0.997	0.003
K22.7 Barrett's oesophagus	0.003	0.997	0.000
R29.4 Clicking hip	0.003	0.997	0.000
R29.3 Abnormal posture	0.003	0.997	0.000
I05.0 Mitral stenosis	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.997	0.000
C90.0 Multiple myeloma	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.997	0.003
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
S42.01 Fracture of clavicle (open)	0.000	0.997	0.002
N02.9 Unspecified	0.003	0.997	0.000
Z13.1 Special screening examination for diabetes mellitus	0.000	0.997	0.003
Z93.1 Gastrostomy status	0.000	0.997	0.003
L91.0 Keloid scar	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.997	0.003
C78.2 Secondary malignant neoplasm of pleura	0.003	0.997	0.000
R29.2 Abnormal reflex	0.002	0.997	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
C44.8 Overlapping lesion of skin	0.000	0.998	0.002
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
N04.9 Unspecified	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
J42 Unspecified chronic bronchitis	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
J18.9 Pneumonia, unspecified	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
N97 Female infertility	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
N97.8 Female infertility of other origin	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.000	0.998	0.002
F24 Induced delusional disorder	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
N97.1 Female infertility of tubal origin	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
L91 Hypertrophic disorders of skin	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
F21 Schizotypal disorder	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
C44.0 Skin of lip	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
K06.1 Gingival enlargement	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
F22 Persistent delusional disorders	0.000	0.998	0.002
L92 Granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
N97.3 Female infertility of cervical origin	0.002	0.998	0.000
N97.2 Female infertility of uterine origin	0.002	0.998	0.000
E66.9 Obesity, unspecified	0.002	0.998	0.000
L91.9 Hypertrophic disorder of skin, unspecified	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
C21.1 Anal canal	0.000	0.998	0.002
T75.4 Effects of electric current	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
N04 Nephrotic syndrome	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
N97.4 Female infertility associated with male factors	0.002	0.998	0.000
N97.0 Female infertility associated with anovulation	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
N04.0 Minor glomerular abnormality	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
L91.8 Other hypertrophic disorders of skin	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
C21.0 Anus, unspecified	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.002	0.998	0.000
N04.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.000	0.998	0.001
L97 Ulcer of lower limb, not elsewhere classified	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.001
F22.8 Other persistent delusional disorders	0.000	0.998	0.001
K22.8 Other specified diseases of oesophagus	0.000	0.998	0.002
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.001	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
W22.9 Unspecified place	0.002	0.998	0.000
L85 Other epidermal thickening	0.002	0.998	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.998	0.002
N04.8 Other	0.001	0.998	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.998	0.000
N04.6 Dense deposit disease	0.001	0.998	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.998	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
T78.9 Adverse effect, unspecified	0.001	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.998	0.000
T75.1 Drowning and nonfatal submersion	0.001	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
N04.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.998	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.998	0.002
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.001	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.001	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.001	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
D14.1 Larynx	0.000	0.998	0.001
K83.1 Obstruction of bile duct	0.000	0.998	0.001
M94.8 Other specified disorders of cartilage	0.001	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.001
C21 Malignant neoplasm of anus and anal canal	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.999	0.001
F23.8 Other acute and transient psychotic disorders	0.000	0.999	0.001
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.999	0.001
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
C69.9 Eye, unspecified	0.000	0.999	0.001
T75.8 Other specified effects of external causes	0.001	0.999	0.000
T75.3 Motion sickness	0.001	0.999	0.000
T75.2 Effects of vibration	0.001	0.999	0.000
T75.0 Effects of lightning	0.001	0.999	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.999	0.001
C44.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.999	0.001
L85.3 Xerosis cutis	0.001	0.999	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.001	0.999	0.000
L85.0 Acquired ichthyosis	0.001	0.999	0.000
L92.0 Granuloma annulare	0.001	0.999	0.000
F03 Unspecified dementia	0.000	0.999	0.001
F60 Specific personality disorders	0.001	0.999	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.001	0.999	0.000
L93 Lupus erythematosus	0.001	0.999	0.000
L87 Transepidermal elimination disorders	0.001	0.999	0.000
L88 Pyoderma gangrenosum	0.001	0.999	0.000
L86 Keratoderma in diseases classified elsewhere	0.001	0.999	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.001	0.999	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.000	0.999	0.001
B07 Viral warts	0.000	0.999	0.001
Y53 Agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.000	0.999	0.001
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.999	0.001
K55.2 Angiodysplasia of colon	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
R60.9 Oedema, unspecified	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.999	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.999	0.001
C21.2 Cloacogenic zone	0.000	0.999	0.001
C69.0 Conjunctiva	0.000	0.999	0.001
Y53.2 Stimulant laxatives	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.001	0.999	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.001	0.999	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.001	0.999	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.001	0.999	0.000
C43.5 Malignant melanoma of trunk	0.000	0.999	0.001
F22.0 Delusional disorder	0.000	0.999	0.001
F60.4 Histrionic personality disorder	0.001	0.999	0.000
S43.0 Dislocation of shoulder joint	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.999	0.001
M94.81 Other specified disorders of cartilage (Shoulder region)	0.001	0.999	0.000
G71.0 Muscular dystrophy	0.001	0.999	0.000
L81.9 Disorder of pigmentation, unspecified	0.001	0.999	0.000
L85.9 Epidermal thickening, unspecified	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.999	0.001
O46.8 Other antepartum haemorrhage	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.999	0.001
Z99.1 Dependence on respirator	0.001	0.999	0.000
S42 Fracture of shoulder and upper arm	0.000	0.999	0.001
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.999	0.001
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.001	0.999	0.000
D12.3 Transverse colon	0.000	0.999	0.001
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
L87.9 Transepidermal elimination disorder, unspecified	0.001	0.999	0.000
L87.8 Other transepidermal elimination disorders	0.001	0.999	0.000
L87.2 Elastosis perforans serpiginosa	0.001	0.999	0.000
L87.1 Reactive perforating collagenosis	0.001	0.999	0.000
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.001	0.999	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.001	0.999	0.000
L93.2 Other local lupus erythematosus	0.001	0.999	0.000
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.001	0.999	0.000
L99.0 Amyloidosis of skin	0.001	0.999	0.000
S42.3 Fracture of shaft of humerus	0.000	0.999	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
V23.4 Driver injured in traffic accident	0.000	0.999	0.001
T71 Asphyxiation	0.001	0.999	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.999	0.001
M94.89 Other specified disorders of cartilage (Site unspecified)	0.001	0.999	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.999	0.001
F05.9 Delirium, unspecified	0.000	0.999	0.001
L93.1 Subacute cutaneous lupus erythematosus	0.001	0.999	0.000
N20.9 Urinary calculus, unspecified	0.001	0.999	0.000
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
Y53.7 Emetics	0.001	0.999	0.000
Y53.5 Digestants	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.999	0.000
Z22.8 Carrier of other infectious diseases	0.000	0.999	0.001
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
C34.1 Upper lobe, bronchus or lung	0.001	0.999	0.000
C69.6 Orbit	0.000	0.999	0.001
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.999	0.001
L30.9 Dermatitis, unspecified	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
S50.0 Contusion of elbow	0.000	0.999	0.001
T78.4 Allergy, unspecified	0.001	0.999	0.000
Z22 Carrier of infectious disease	0.000	0.999	0.001
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
E80.4 Gilbert's syndrome	0.000	0.999	0.001
F60.0 Paranoid personality disorder	0.001	0.999	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.999	0.001
L89.2 Stage III decubitus ulcer	0.001	0.999	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.001	0.999	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
M40.29 Other and unspecified kyphosis (Site unspecified)	0.001	0.999	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.999	0.001
C69.5 Lachrymal gland and duct	0.000	0.999	0.001
C69.1 Cornea	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.001	0.999	0.000
L93.0 Discoid lupus erythematosus	0.001	0.999	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.999	0.001
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.999	0.001
E65-E68 Obesity and other hyperalimentation	0.001	0.999	0.000
B08.1 Molluscum contagiosum	0.000	0.999	0.001
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
L94.3 Sclerodactyly	0.001	0.999	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.999	0.001
S42.1 Fracture of scapula	0.000	0.999	0.001
L94 Other localised connective tissue disorders	0.001	0.999	0.000
L89 Decubitus ulcer	0.001	0.999	0.000
L80 Vitiligo	0.001	0.999	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M25.86 Other specified joint disorders (Lower leg)	0.001	0.999	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.999	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.999	0.001
F60.8 Other specific personality disorders	0.001	0.999	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
Y48.3 Local anaesthetics	0.001	0.999	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.001	0.999	0.000
T70 Effects of air pressure and water pressure	0.001	0.999	0.000
U50 Level of care administered to neonates	0.000	0.999	0.001
U07 Emergency use of U07	0.000	0.999	0.001
U06 Emergency use of U06	0.000	0.999	0.001
U04 Severe acute respiratory syndrome [SARS]	0.000	0.999	0.001
U52 First in a series of a regular day/night admissions	0.000	0.999	0.001
C69.2 Retina	0.000	0.999	0.001
F60.7 Dependent personality disorder	0.001	0.999	0.000
G31.2 Degeneration of nervous system due to alcohol	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
J38.2 Nodules of vocal cords	0.001	0.999	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.001	0.999	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.999	0.001
Z22.3 Carrier of other specified bacterial diseases	0.000	0.999	0.001
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.999	0.001
T74 Maltreatment syndromes	0.001	0.999	0.000
T69 Other effects of reduced temperature	0.001	0.999	0.000
T67 Effects of heat and light	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
I05-I09 Chronic rheumatic heart diseases	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.001	0.999	0.000
L94.8 Other specified localised connective tissue disorders	0.001	0.999	0.000
R41.1 Anterograde amnesia	0.000	0.999	0.001
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.999	0.001
Y58.0 BCG vaccine	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
Z22.9 Carrier of infectious disease, unspecified	0.000	0.999	0.001
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.000	0.999	0.001
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.000	0.999	0.001
Z22.2 Carrier of diphtheria	0.000	0.999	0.001
Z22.0 Carrier of typhoid	0.000	0.999	0.001
Z24.5 Need for immunisation against rubella alone	0.000	0.999	0.001
Z52.4 Kidney donor	0.000	0.999	0.001
T73 Effects of other deprivation	0.001	0.999	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
F60.5 Anankastic personality disorder	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.000	0.999	0.001
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.999	0.001
E67 Other hyperalimentation	0.001	0.999	0.000
E68 Sequelae of hyperalimentation	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.999	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.999	0.000
S42.11 Fracture of scapula (open)	0.000	0.999	0.001
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.999	0.001
C69.4 Ciliary body	0.000	0.999	0.001
H36.0 Diabetic retinopathy	0.001	0.999	0.000
L94.6 Ainhum	0.001	0.999	0.000
L94.5 Poikiloderma vasculare atrophicans	0.001	0.999	0.000
L94.4 Gottron's papules	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations