TreeWAS – Variant ID: rs12374220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M19.0 Primary arthrosis of other joints	0.024	0.976	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.024	0.976	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.023	0.977	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.023	0.977	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.020	0.980	0.000
M19.08 Primary arthrosis of other joints (Other)	0.018	0.982	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.018	0.982	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.018	0.982	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.018	0.982	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.018	0.982	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.017	0.983	0.000
M16.1 Other primary coxarthrosis	0.016	0.984	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.986	0.014
M19 Other arthrosis	0.014	0.986	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.986	0.014
M16.0 Primary coxarthrosis, bilateral	0.013	0.987	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.987	0.013
M16 Coxarthrosis [arthrosis of hip]	0.013	0.987	0.000
C44 Other malignant neoplasms of skin	0.000	0.988	0.012
M15-M19 Arthrosis	0.012	0.988	0.000
C44.0 Skin of lip	0.000	0.988	0.012
C44.2 Skin of ear and external auricular canal	0.000	0.989	0.011
M18 Arthrosis of first carpometacarpal joint	0.011	0.989	0.000
C44.7 Skin of lower limb, including hip	0.000	0.989	0.010
M19.8 Other specified arthrosis	0.010	0.990	0.000
M19.2 Other secondary arthrosis	0.010	0.990	0.000
M19.1 Posttraumatic arthrosis of other joints	0.010	0.990	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.010	0.990	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.010	0.990	0.000
M16.5 Other posttraumatic coxarthrosis	0.010	0.990	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.010	0.990	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.010	0.990	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.009	0.991	0.000
M15 Polyarthrosis	0.009	0.991	0.000
C44.8 Overlapping lesion of skin	0.000	0.991	0.009
M16.7 Other secondary coxarthrosis	0.009	0.991	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.992	0.008
C67.6 Ureteric orifice	0.008	0.992	0.000
M16.3 Other dysplastic coxarthrosis	0.008	0.992	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.008	0.992	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.008	0.992	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.008	0.992	0.000
M19.28 Other secondary arthrosis (Other)	0.008	0.992	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.008	0.992	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.008	0.992	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.008	0.992	0.000
M19.24 Other secondary arthrosis (Hand)	0.008	0.992	0.000
M19.23 Other secondary arthrosis (Forearm)	0.008	0.992	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.008	0.992	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.008	0.992	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.008	0.992	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.008	0.992	0.000
M19.88 Other specified arthrosis (Other)	0.008	0.992	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.008	0.992	0.000
M19.86 Other specified arthrosis (Lower leg)	0.008	0.992	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.008	0.992	0.000
M19.84 Other specified arthrosis (Hand)	0.008	0.992	0.000
M19.83 Other specified arthrosis (Forearm)	0.008	0.992	0.000
M19.82 Other specified arthrosis (Upper arm)	0.008	0.992	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.008	0.992	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.008	0.992	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.007	0.992	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.007	0.992	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.007	0.992	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.007	0.992	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.007	0.992	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.007	0.992	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.007	0.992	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.007	0.992	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.007	0.992	0.000
Z87 Personal history of other diseases and conditions	0.000	0.993	0.007
Z87.8 Personal history of other specified conditions	0.000	0.993	0.007
M15.1 Heberden's nodes (with arthropathy)	0.007	0.993	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.007	0.993	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.993	0.007
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
M15.9 Polyarthrosis, unspecified	0.007	0.993	0.000
M15.0 Primary generalised (osteo)arthrosis	0.007	0.993	0.000
M15.8 Other polyarthrosis	0.007	0.993	0.000
M15.4 Erosive (osteo)arthrosis	0.007	0.993	0.000
M15.3 Secondary multiple arthrosis	0.007	0.993	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.007	0.993	0.000
C67.4 Posterior wall of bladder	0.007	0.993	0.000
C67.1 Dome of bladder	0.006	0.994	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.994	0.006
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.994	0.005
C67.0 Trigone of bladder	0.005	0.995	0.000
C44.4 Skin of scalp and neck	0.000	0.995	0.005
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
C67.7 Urachus	0.005	0.995	0.000
C67.3 Anterior wall of bladder	0.005	0.995	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.005	0.995	0.000
M15.99 Polyosteoarthritis, unspecified	0.005	0.995	0.000
C67.2 Lateral wall of bladder	0.005	0.995	0.000
C44.5 Skin of trunk	0.000	0.995	0.005
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.995	0.005
W19.9 Unspecified place	0.005	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
C67.5 Bladder neck	0.005	0.995	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.005	0.995	0.000
F05.9 Delirium, unspecified	0.004	0.996	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.004	0.996	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.996	0.004
C44.6 Skin of upper limb, including shoulder	0.000	0.996	0.003
C64-C68 Malignant neoplasms of urinary tract	0.004	0.996	0.000
Y40.0 Penicillins	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.000	0.997	0.003
C65 Malignant neoplasm of renal pelvis	0.003	0.997	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.997	0.003
T81.8 Other complications of procedures, not elsewhere classified	0.000	0.997	0.003
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
M19.9 Arthrosis, unspecified	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
M17 Gonarthrosis [arthrosis of knee]	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
W19 Unspecified fall	0.003	0.997	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Z88.5 Personal history of allergy to narcotic agent	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.997	0.003
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.997	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.997	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
U80.1 Methicillin resistant agent	0.000	0.997	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
J18.1 Lobar pneumonia, unspecified	0.000	0.998	0.002
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.002	0.998	0.000
C68.1 Paraurethral glands	0.002	0.998	0.000
C68.0 Urethra	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
M17.5 Other secondary gonarthrosis	0.002	0.998	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.002	0.998	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
W19.1 Residential institution	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
W19.8 Other specified place	0.002	0.998	0.000
W19.5 Trade and service area	0.002	0.998	0.000
W19.0 Home	0.002	0.998	0.000
W19.7 Farm	0.002	0.998	0.000
W19.6 Industrial and construction area	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M17.3 Other posttraumatic gonarthrosis	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
W19.4 Street and highway	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
W19.3 Sports and athletics area	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
Z95.2 Presence of prosthetic heart valve	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
W19.09 Unspecified fall; Home; During unspecified activity	0.002	0.998	0.000
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.002	0.998	0.000
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.002	0.998	0.000
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.002	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.998	0.002
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
H36 Retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.001	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
Q54.8 Other hypospadias	0.001	0.998	0.000
Q54.4 Congenital chordee	0.001	0.998	0.000
Q54.3 Hypospadias, perineal	0.001	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.998	0.000
Q54.1 Hypospadias, penile	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations