TreeWAS – Variant ID: rs12375901

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O60-O75 Complications of labour and delivery	0.097	0.903
O68 Labour and delivery complicated by foetal stress [distress]	0.094	0.906
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.090	0.910
O70 Perineal laceration during delivery	0.087	0.913
O63 Long labour	0.087	0.913
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.083	0.917
O63.1 Prolonged second stage (of labour)	0.080	0.920
O69 Labour and delivery complicated by umbilical cord complications	0.079	0.920
Chapter XV Pregnancy, childbirth and the puerperium	0.077	0.923
O61 Failed induction of labour	0.076	0.924
O66 Other obstructed labour	0.075	0.925
O75 Other complications of labour and delivery, not elsewhere classified	0.074	0.926
O70.1 Second degree perineal laceration during delivery	0.073	0.927
O20-O29 Other maternal disorders predominantly related to pregnancy	0.073	0.927
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.073	0.927
O64 Obstructed labour due to malposition and malpresentation of foetus	0.072	0.928
O69.1 Labour and delivery complicated by cord around neck, with compression	0.071	0.929
O72 Postpartum haemorrhage	0.071	0.929
O70.0 First degree perineal laceration during delivery	0.071	0.929
O70.2 Third degree perineal laceration during delivery	0.070	0.930
O74 Complications of anaesthesia during labour and delivery	0.069	0.931
O73 Retained placenta and membranes, without haemorrhage	0.069	0.931
O71 Other obstetric trauma	0.069	0.931
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.069	0.931
O65 Obstructed labour due to maternal pelvic abnormality	0.069	0.931
O60 Preterm delivery	0.069	0.931
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.069	0.931
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.067	0.932
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.067	0.933
O62 Abnormalities of forces of labour	0.064	0.936
O20 Haemorrhage in early pregnancy	0.064	0.936
O75.2 Pyrexia during labour, not elsewhere classified	0.063	0.936
O26 Maternal care for other conditions predominantly related to pregnancy	0.063	0.937
O70.9 Perineal laceration during delivery, unspecified	0.063	0.937
O70.3 Fourth degree perineal laceration during delivery	0.063	0.937
O63.9 Long labour, unspecified	0.062	0.938
O63.2 Delayed delivery of second twin, triplet, etc.	0.062	0.938
O63.0 Prolonged first stage (of labour)	0.062	0.938
O61.0 Failed medical induction of labour	0.061	0.939
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.059	0.941
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.059	0.941
O24 Diabetes mellitus in pregnancy	0.057	0.943
O69.9 Labour and delivery complicated by cord complication, unspecified	0.057	0.943
O69.8 Labour and delivery complicated by other cord complications	0.057	0.943
O69.5 Labour and delivery complicated by vascular lesion of cord	0.057	0.943
O69.4 Labour and delivery complicated by vasa praevia	0.057	0.943
O69.3 Labour and delivery complicated by short cord	0.057	0.943
O69.0 Labour and delivery complicated by prolapse of cord	0.057	0.943
O85-O92 Complications predominantly related to the puerperium	0.056	0.944
O16 Unspecified maternal hypertension	0.055	0.945
O26.9 Pregnancy-related condition, unspecified	0.055	0.945
O61.9 Failed induction of labour, unspecified	0.054	0.945
O61.8 Other failed induction of labour	0.054	0.945
O61.1 Failed instrumental induction of labour	0.054	0.945
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.054	0.946
O64.1 Obstructed labour due to breech presentation	0.054	0.946
O72.0 Third-stage haemorrhage	0.054	0.946
O20.0 Threatened abortion	0.054	0.946
O72.2 Delayed and secondary postpartum haemorrhage	0.054	0.946
O66.9 Obstructed labour, unspecified	0.054	0.946
O66.8 Other specified obstructed labour	0.054	0.946
O66.4 Failed trial of labour, unspecified	0.054	0.946
O66.3 Obstructed labour due to other abnormalities of foetus	0.054	0.946
O66.2 Obstructed labour due to unusually large foetus	0.054	0.946
O66.1 Obstructed labour due to locked twins	0.054	0.946
O66.0 Obstructed labour due to shoulder dystocia	0.054	0.946
O00-O08 Pregnancy with abortive outcome	0.053	0.947
O94-O99 Other obstetric conditions, not elsewhere classified	0.053	0.947
O75.9 Complication of labour and delivery, unspecified	0.053	0.947
O75.5 Delayed delivery after artificial rupture of membranes	0.053	0.947
O75.4 Other complications of obstetric surgery and procedures	0.053	0.947
O75.3 Other infection during labour	0.053	0.947
O75.1 Shock during or following labour and delivery	0.053	0.947
O75.0 Maternal distress during labour and delivery	0.053	0.947
O29 Complications of anaesthesia during pregnancy	0.053	0.947
O28 Abnormal findings on antenatal screening of mother	0.053	0.947
O23 Infections of genito-urinary tract in pregnancy	0.053	0.947
O22 Venous complications in pregnancy	0.053	0.947
O21 Excessive vomiting in pregnancy	0.053	0.947
O25 Malnutrition in pregnancy	0.053	0.947
O75.8 Other specified complications of labour and delivery	0.052	0.948
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.052	0.948
O64.8 Obstructed labour due to other malposition and malpresentation	0.052	0.948
O64.5 Obstructed labour due to compound presentation	0.052	0.948
O64.4 Obstructed labour due to shoulder presentation	0.052	0.948
O64.3 Obstructed labour due to brow presentation	0.052	0.948
O64.2 Obstructed labour due to face presentation	0.052	0.948
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.052	0.948
O20.9 Haemorrhage in early pregnancy, unspecified	0.052	0.948
O72.3 Postpartum coagulation defects	0.051	0.949
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.051	0.949
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.050	0.950
O75.7 Vaginal delivery following previous Caesarean section	0.050	0.950
O60.3 Preterm delivery without spontaneous labour	0.050	0.950
O60.2 Preterm spontaneous labour with term delivery	0.050	0.950
O60.1 Preterm spontaneous labour with preterm delivery	0.050	0.950
O60.0 Preterm labour without delivery	0.050	0.950
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.050	0.950
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.050	0.950
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.050	0.950
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.050	0.950
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.050	0.950
O65.2 Obstructed labour due to pelvic inlet contraction	0.050	0.950
O65.1 Obstructed labour due to generally contracted pelvis	0.050	0.950
O65.0 Obstructed labour due to deformed pelvis	0.050	0.950
O67.9 Intrapartum haemorrhage, unspecified	0.050	0.950
O67.8 Other intrapartum haemorrhage	0.050	0.950
O67.0 Intrapartum haemorrhage with coagulation defect	0.050	0.950
O71.9 Obstetric trauma, unspecified	0.050	0.950
O71.8 Other specified obstetric trauma	0.050	0.950
O71.7 Obstetric haematoma of pelvis	0.050	0.950
O71.6 Obstetric damage to pelvic joints and ligaments	0.050	0.950
O71.5 Other obstetric injury to pelvic organs	0.050	0.950
O71.4 Obstetric high vaginal laceration alone	0.050	0.950
O71.3 Obstetric laceration of cervix	0.050	0.950
O71.2 Postpartum inversion of uterus	0.050	0.950
O71.1 Rupture of uterus during labour	0.050	0.950
O71.0 Rupture of uterus before onset of labour	0.050	0.950
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.050	0.950
O73.0 Retained placenta, without haemorrhage	0.050	0.950
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.050	0.950
O74.8 Other complications of anaesthesia during labour and delivery	0.050	0.950
O74.7 Failed or difficult intubation during labour and delivery	0.050	0.950
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.050	0.950
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.050	0.950
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.050	0.950
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.050	0.950
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.050	0.950
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.050	0.950
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.050	0.950
O15 Eclampsia	0.049	0.951
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.049	0.951
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.049	0.951
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.049	0.951
O26.8 Other specified pregnancy-related conditions	0.049	0.951
O69.2 Labour and delivery complicated by other cord entanglement	0.048	0.951
O80-O84 Delivery	0.049	0.951
O24.4 Diabetes mellitus arising in pregnancy	0.046	0.954
O62.9 Abnormality of forces of labour, unspecified	0.046	0.954
O62.8 Other abnormalities of forces of labour	0.046	0.954
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.046	0.954
O62.3 Precipitate labour	0.046	0.954
O62.1 Secondary uterine inertia	0.046	0.954
O62.0 Primary inadequate contractions	0.046	0.954
O20.8 Other haemorrhage in early pregnancy	0.046	0.954
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.045	0.954
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.045	0.954
O26.5 Maternal hypotension syndrome	0.045	0.954
O26.4 Herpes gestationis	0.045	0.954
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.045	0.954
O26.2 Pregnancy care of habitual aborter	0.045	0.954
O26.1 Low weight gain in pregnancy	0.045	0.954
O26.0 Excessive weight gain in pregnancy	0.045	0.954
O72.1 Other immediate postpartum haemorrhage	0.045	0.955
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.045	0.955
O47 False labour	0.043	0.957
O35 Maternal care for known or suspected foetal abnormality and damage	0.042	0.958
O24.9 Diabetes mellitus in pregnancy, unspecified	0.041	0.959
O24.3 Pre-existing diabetes mellitus, unspecified	0.041	0.959
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.041	0.959
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.041	0.959
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.041	0.959
O62.2 Other uterine inertia	0.041	0.959
O00 Ectopic pregnancy	0.041	0.959
O92 Other disorders of breast and lactation associated with childbirth	0.040	0.960
O91 Infections of breast associated with childbirth	0.040	0.960
O90 Complications of the puerperium, not elsewhere classified	0.040	0.960
O89 Complications of anaesthesia during the puerperium	0.040	0.960
O88 Obstetric embolism	0.040	0.960
O87 Venous complications in the puerperium	0.040	0.960
O86 Other puerperal infections	0.040	0.960
O85 Puerperal sepsis	0.040	0.960
O04 Medical abortion	0.039	0.961
O43 Placental disorders	0.039	0.961
O41 Other disorders of amniotic fluid and membranes	0.039	0.961
O08 Complications following abortion and ectopic and molar pregnancy	0.038	0.961
O07 Failed attempted abortion	0.038	0.961
O06 Unspecified abortion	0.038	0.961
O05 Other abortion	0.038	0.961
O01 Hydatidiform mole	0.038	0.961
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.038	0.962
O97 Death from sequelae of direct obstetric causes	0.038	0.962
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.038	0.962
O95 Obstetric death of unspecified cause	0.038	0.962
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.038	0.962
O21.9 Vomiting of pregnancy, unspecified	0.038	0.962
O21.8 Other vomiting complicating pregnancy	0.038	0.962
O21.2 Late vomiting of pregnancy	0.038	0.962
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.038	0.962
O21.0 Mild hyperemesis gravidarum	0.038	0.962
O22.9 Venous complication in pregnancy, unspecified	0.038	0.962
O22.8 Other venous complications in pregnancy	0.038	0.962
O22.5 Cerebral venous thrombosis in pregnancy	0.038	0.962
O22.4 Haemorrhoids in pregnancy	0.038	0.962
O22.3 Deep phlebothrombosis in pregnancy	0.038	0.962
O22.2 Superficial thrombophlebitis in pregnancy	0.038	0.962
O22.1 Genital varices in pregnancy	0.038	0.962
O22.0 Varicose veins of lower extremity in pregnancy	0.038	0.962
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.038	0.962
O23.5 Infections of the genital tract in pregnancy	0.038	0.962
O23.4 Unspecified infection of urinary tract in pregnancy	0.038	0.962
O23.3 Infections of other parts of urinary tract in pregnancy	0.038	0.962
O23.2 Infections of urethra in pregnancy	0.038	0.962
O23.1 Infections of bladder in pregnancy	0.038	0.962
O23.0 Infections of kidney in pregnancy	0.038	0.962
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.038	0.962
O28.8 Other abnormal findings on antenatal screening of mother	0.038	0.962
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.038	0.962
O28.4 Abnormal radiological finding on antenatal screening of mother	0.038	0.962
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.038	0.962
O28.2 Abnormal cytological finding on antenatal screening of mother	0.038	0.962
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.038	0.962
O28.0 Abnormal haematological finding on antenatal screening of mother	0.038	0.962
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.038	0.962
O29.8 Other complications of anaesthesia during pregnancy	0.038	0.962
O29.6 Failed or difficult intubation during pregnancy	0.038	0.962
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.038	0.962
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.038	0.962
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.038	0.962
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.038	0.962
O29.1 Cardiac complications of anaesthesia during pregnancy	0.038	0.962
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.038	0.962
O34 Maternal care for known or suspected abnormality of pelvic organs	0.038	0.962
O03 Spontaneous abortion	0.037	0.963
O14.9 Preeclampsia, unspecified	0.037	0.963
O45 Premature separation of placenta [abruptio placentae]	0.037	0.963
O44 Placenta praevia	0.037	0.963
O33 Maternal care for known or suspected disproportion	0.037	0.963
O31 Complications specific to multiple gestation	0.037	0.963
O40 Polyhydramnios	0.037	0.963
O47.9 False labour, unspecified	0.036	0.963
O32 Maternal care for known or suspected malpresentation of foetus	0.036	0.964
O14.2 HELLP syndrome	0.036	0.964
O14.1 Severe preeclampsia	0.036	0.964
O14.0 Moderate preeclampsia	0.036	0.964
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.036	0.964
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.036	0.964
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.035	0.964
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.035	0.964
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.035	0.964
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.035	0.964
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.035	0.964
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.035	0.964
O12.2 Gestational oedema with proteinuria	0.035	0.964
O12.1 Gestational proteinuria	0.035	0.964
O12.0 Gestational oedema	0.035	0.964
O15.9 Eclampsia, unspecified as to time period	0.035	0.964
O15.2 Eclampsia in the puerperium	0.035	0.964
O15.1 Eclampsia in labour	0.035	0.964
O15.0 Eclampsia in pregnancy	0.035	0.964
O46 Antepartum haemorrhage, not elsewhere classified	0.035	0.965
O84 Multiple delivery	0.035	0.965
O83 Other assisted single delivery	0.035	0.965
O81 Single delivery by forceps and vacuum extractor	0.035	0.965
O02 Other abnormal products of conception	0.034	0.966
O47.0 False labour before 37 completed weeks of gestation	0.033	0.967
O82 Single delivery by Caesarean section	0.033	0.967
O36 Maternal care for other known or suspected foetal problems	0.033	0.967
O30 Multiple gestation	0.032	0.968
O00.1 Tubal pregnancy	0.031	0.968
O47.1 False labour at or after 37 completed weeks of gestation	0.031	0.969
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.030	0.969
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.030	0.969
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.030	0.969
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.030	0.969
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.030	0.969
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.030	0.969
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.030	0.969
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.030	0.969
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.030	0.969
O80 Single spontaneous delivery	0.030	0.969
O43.8 Other placental disorders	0.030	0.970
O41.8 Other specified disorders of amniotic fluid and membranes	0.030	0.970
O00.9 Ectopic pregnancy, unspecified	0.029	0.971
O00.8 Other ectopic pregnancy	0.029	0.971
O00.2 Ovarian pregnancy	0.029	0.971
O00.0 Abdominal pregnancy	0.029	0.971
O04.9 Complete or unspecified, without complication	0.029	0.971
O86.8 Other specified puerperal infections	0.029	0.971
O86.4 Pyrexia of unknown origin following delivery	0.029	0.971
O86.3 Other genito-urinary tract infections following delivery	0.029	0.971
O86.2 Urinary tract infection following delivery	0.029	0.971
O86.1 Other infection of genital tract following delivery	0.029	0.971
O86.0 Infection of obstetric surgical wound	0.029	0.971
O87.9 Venous complication in the puerperium, unspecified	0.029	0.971
O87.8 Other venous complications in the puerperium	0.029	0.971
O87.3 Cerebral venous thrombosis in the puerperium	0.029	0.971
O87.2 Haemorrhoids in the puerperium	0.029	0.971
O87.1 Deep phlebothrombosis in the puerperium	0.029	0.971
O87.0 Superficial thrombophlebitis in the puerperium	0.029	0.971
O88.8 Other obstetric embolism	0.029	0.971
O88.3 Obstetric pyaemic and septic embolism	0.029	0.971
O88.2 Obstetric blood-clot embolism	0.029	0.971
O88.1 Amniotic fluid embolism	0.029	0.971
O88.0 Obstetric air embolism	0.029	0.971
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.029	0.971
O89.8 Other complications of anaesthesia during the puerperium	0.029	0.971
O89.6 Failed or difficult intubation during the puerperium	0.029	0.971
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.029	0.971
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.029	0.971
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.029	0.971
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.029	0.971
O89.1 Cardiac complications of anaesthesia during the puerperium	0.029	0.971
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.029	0.971
O90.9 Complication of the puerperium, unspecified	0.029	0.971
O90.8 Other complications of the puerperium, not elsewhere classified	0.029	0.971
O90.5 Postpartum thyroiditis	0.029	0.971
O90.4 Postpartum acute renal failure	0.029	0.971
O90.3 Cardiomyopathy in the puerperium	0.029	0.971
O90.2 Haematoma of obstetric wound	0.029	0.971
O90.1 Disruption of perineal obstetric wound	0.029	0.971
O90.0 Disruption of Caesarean section wound	0.029	0.971
O91.2 Nonpurulent mastitis associated with childbirth	0.029	0.971
O91.1 Abscess of breast associated with childbirth	0.029	0.971
O91.0 Infection of nipple associated with childbirth	0.029	0.971
O92.7 Other and unspecified disorders of lactation	0.029	0.971
O92.6 Galactorrhoea	0.029	0.971
O92.5 Suppressed lactation	0.029	0.971
O92.4 Hypogalactia	0.029	0.971
O92.3 Agalactia	0.029	0.971
O92.2 Other and unspecified disorders of breast associated with childbirth	0.029	0.971
O92.1 Cracked nipple associated with childbirth	0.029	0.971
O92.0 Retracted nipple associated with childbirth	0.029	0.971
O32.2 Maternal care for transverse and oblique lie	0.029	0.971
O48 Prolonged pregnancy	0.029	0.971
O03.9 Complete or unspecified, without complication	0.029	0.971
O04.8 Complete or unspecified, with other and unspecified complications	0.028	0.971
O04.7 Complete or unspecified, complicated by embolism	0.028	0.971
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.028	0.971
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.028	0.971
O04.4 Incomplete, without complication	0.028	0.971
O04.3 Incomplete, with other and unspecified complications	0.028	0.971
O04.2 Incomplete, complicated by embolism	0.028	0.971
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.028	0.971
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.028	0.971
O34.2 Maternal care due to uterine scar from previous surgery	0.028	0.972
O43.9 Placental disorder, unspecified	0.028	0.972
O43.2 Morbidly adherent placenta	0.028	0.972
O43.1 Malformation of placenta	0.028	0.972
O43.0 Placental transfusion syndromes	0.028	0.972
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.028	0.972
O41.1 Infection of amniotic sac and membranes	0.028	0.972
O41.0 Oligohydramnios	0.028	0.972
O01.9 Hydatidiform mole, unspecified	0.028	0.972
O01.1 Incomplete and partial hydatidiform mole	0.028	0.972
O01.0 Classical hydatidiform mole	0.028	0.972
O05.9 Complete or unspecified, without complication	0.028	0.972
O05.8 Complete or unspecified, with other and unspecified complications	0.028	0.972
O05.7 Complete or unspecified, complicated by embolism	0.028	0.972
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.028	0.972
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.028	0.972
O05.4 Incomplete, without complication	0.028	0.972
O05.3 Incomplete, with other and unspecified complications	0.028	0.972
O05.2 Incomplete, complicated by embolism	0.028	0.972
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.028	0.972
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.028	0.972
O06.9 Complete or unspecified, without complication	0.028	0.972
O06.8 Complete or unspecified, with other and unspecified complications	0.028	0.972
O06.7 Complete or unspecified, complicated by embolism	0.028	0.972
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.028	0.972
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.028	0.972
O06.4 Incomplete, without complication	0.028	0.972
O06.3 Incomplete, with other and unspecified complications	0.028	0.972
O06.2 Incomplete, complicated by embolism	0.028	0.972
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.028	0.972
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.028	0.972
O07.9 Other and unspecified failed attempted abortion, without complication	0.028	0.972
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.028	0.972
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.028	0.972
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.028	0.972
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.028	0.972
O07.4 Failed medical abortion, without complication	0.028	0.972
O07.3 Failed medical abortion, with other and unspecified complications	0.028	0.972
O07.2 Failed medical abortion, complicated by embolism	0.028	0.972
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.028	0.972
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.028	0.972
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.028	0.972
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.028	0.972
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.028	0.972
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.028	0.972
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.028	0.972
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.028	0.972
O08.3 Shock following abortion and ectopic and molar pregnancy	0.028	0.972
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.028	0.972
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.028	0.972
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.028	0.972
O96.9 Death from unspecified obstetric cause	0.028	0.972
O96.1 Death from indirect obstetric cause	0.028	0.972
O96.0 Death from direct obstetric cause	0.028	0.972
O97.9 Death from sequelae of obstetric cause, unspecified	0.028	0.972
O97.1 Death from sequelae of indirect obstetric cause	0.028	0.972
O97.0 Death from sequelae of direct obstetric cause	0.028	0.972
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.028	0.972
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.028	0.972
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.027	0.973
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.027	0.973
O34.8 Maternal care for other abnormalities of pelvic organs	0.027	0.973
O34.7 Maternal care for abnormality of vulva and perineum	0.027	0.973
O34.6 Maternal care for abnormality of vagina	0.027	0.973
O34.5 Maternal care for other abnormalities of gravid uterus	0.027	0.973
O34.4 Maternal care for other abnormalities of cervix	0.027	0.973
O34.3 Maternal care for cervical incompetence	0.027	0.973
O34.1 Maternal care for tumour of corpus uteri	0.027	0.973
O34.0 Maternal care for congenital malformation of uterus	0.027	0.973
O03.8 Complete or unspecified, with other and unspecified complications	0.027	0.973
O03.7 Complete or unspecified, complicated by embolism	0.027	0.973
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.027	0.973
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.027	0.973
O03.3 Incomplete, with other and unspecified complications	0.027	0.973
O03.2 Incomplete, complicated by embolism	0.027	0.973
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.027	0.973
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.027	0.973
O31.8 Other complications specific to multiple gestation	0.026	0.973
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.026	0.973
O31.1 Continuing pregnancy after abortion of one foetus or more	0.026	0.973
O31.0 Papyraceous foetus	0.026	0.973
O33.9 Maternal care for disproportion, unspecified	0.026	0.973
O33.8 Maternal care for disproportion of other origin	0.026	0.973
O33.7 Maternal care for disproportion due to other foetal deformities	0.026	0.973
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.026	0.973
O33.5 Maternal care for disproportion due to unusually large foetus	0.026	0.973
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.026	0.973
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.026	0.973
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.026	0.973
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.026	0.973
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.026	0.973
O44.1 Placenta praevia with haemorrhage	0.026	0.973
O44.0 Placenta praevia specified as without haemorrhage	0.026	0.973
O45.9 Premature separation of placenta, unspecified	0.026	0.973
O45.8 Other premature separation of placenta	0.026	0.973
O45.0 Premature separation of placenta with coagulation defect	0.026	0.973
O32.9 Maternal care for malpresentation of foetus, unspecified	0.026	0.974
O32.8 Maternal care for other malpresentation of foetus	0.026	0.974
O32.6 Maternal care for compound presentation	0.026	0.974
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.026	0.974
O32.4 Maternal care for high head at term	0.026	0.974
O32.3 Maternal care for face, brow and chin presentation	0.026	0.974
O32.0 Maternal care for unstable lie	0.026	0.974
O36.8 Maternal care for other specified foetal problems	0.026	0.974
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.026	0.974
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.026	0.974
O42 Premature rupture of membranes	0.026	0.974
O46.8 Other antepartum haemorrhage	0.025	0.974
O46.0 Antepartum haemorrhage with coagulation defect	0.025	0.974
O81.5 Delivery by combination of forceps and vacuum extractor	0.025	0.975
O81.4 Vacuum extractor delivery	0.025	0.975
O81.3 Other and unspecified forceps delivery	0.025	0.975
O81.2 Mid-cavity forceps with rotation	0.025	0.975
O81.1 Mid-cavity forceps delivery	0.025	0.975
O81.0 Low forceps delivery	0.025	0.975
O83.9 Assisted single delivery, unspecified	0.025	0.975
O83.8 Other specified assisted single delivery	0.025	0.975
O83.4 Destructive operation for delivery	0.025	0.975
O83.3 Delivery of viable foetus in abdominal pregnancy	0.025	0.975
O83.2 Other manipulation-assisted delivery	0.025	0.975
O83.1 Other assisted breech delivery	0.025	0.975
O83.0 Breech extraction	0.025	0.975
O84.9 Multiple delivery, unspecified	0.025	0.975
O84.8 Other multiple delivery	0.025	0.975
O84.2 Multiple delivery, all by Caesarean section	0.025	0.975
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.025	0.975
O84.0 Multiple delivery, all spontaneous	0.025	0.975
O02.9 Abnormal product of conception, unspecified	0.024	0.975
O02.8 Other specified abnormal products of conception	0.024	0.975
O02.0 Blighted ovum and nonhydatidiform mole	0.024	0.975
O82.9 Delivery by Caesarean section, unspecified	0.024	0.976
O82.8 Other single delivery by Caesarean section	0.024	0.976
O82.2 Delivery by Caesarean hysterectomy	0.024	0.976
O82.1 Delivery by emergency Caesarean section	0.024	0.976
O46.9 Antepartum haemorrhage, unspecified	0.024	0.976
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.023	0.976
O36.4 Maternal care for intra-uterine death	0.023	0.976
O36.3 Maternal care for signs of foetal hypoxia	0.023	0.976
O36.2 Maternal care for hydrops foetalis	0.023	0.976
O36.1 Maternal care for other isoimmunisation	0.023	0.976
O30.9 Multiple gestation, unspecified	0.023	0.977
O30.8 Other multiple gestation	0.023	0.977
O30.2 Quadruplet pregnancy	0.023	0.977
O30.1 Triplet pregnancy	0.023	0.977
O03.4 Incomplete, without complication	0.023	0.977
O36.9 Maternal care for foetal problem, unspecified	0.023	0.977
O36.6 Maternal care for excessive foetal growth	0.023	0.977
O82.0 Delivery by elective Caesarean section	0.022	0.978
O80.8 Other single spontaneous delivery	0.022	0.978
O80.1 Spontaneous breech delivery	0.022	0.978
O32.1 Maternal care for breech presentation	0.022	0.978
O36.5 Maternal care for poor foetal growth	0.022	0.978

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations