TreeWAS – Variant ID: rs12378446

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z51.8 Other specified medical care	0.000	0.974	0.026
K51.9 Ulcerative colitis, unspecified	0.000	0.977	0.023
K51 Ulcerative colitis	0.000	0.986	0.014
N18.0 End-stage renal disease	0.000	0.986	0.014
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.987	0.013
K51.8 Other ulcerative colitis	0.000	0.988	0.012
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.989	0.011
K51.4 Pseudopolyposis of colon	0.000	0.989	0.011
T92.1 Sequelae of fracture of arm	0.011	0.989	0.000
Z49.1 Extracorporeal dialysis	0.000	0.990	0.010
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.990	0.009
T92 Sequelae of injuries of upper limb	0.009	0.991	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.991	0.009
J33.0 Polyp of nasal cavity	0.000	0.991	0.009
K51.5 Mucosal proctocolitis	0.000	0.991	0.008
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.009	0.991	0.000
T92.0 Sequelae of open wound of upper limb	0.008	0.992	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.992	0.008
T92.4 Sequelae of injury of nerve of upper limb	0.008	0.992	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.008	0.992	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.007	0.993	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.007	0.993	0.000
N18 Chronic renal failure	0.000	0.993	0.007
K51.2 Ulcerative (chronic) proctitis	0.000	0.993	0.007
R07.2 Precordial pain	0.000	0.993	0.007
Z49 Care involving dialysis	0.000	0.993	0.007
T92.8 Sequelae of other specified injuries of upper limb	0.007	0.993	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.007	0.993	0.000
Z49.0 Preparatory care for dialysis	0.000	0.993	0.007
S64.4 Injury of digital nerve of other finger	0.000	0.994	0.006
K14.8 Other diseases of tongue	0.000	0.994	0.006
F20.9 Schizophrenia, unspecified	0.000	0.994	0.006
R26 Abnormalities of gait and mobility	0.000	0.994	0.006
H02.0 Entropion and trichiasis of eyelid	0.000	0.994	0.006
K14.0 Glossitis	0.000	0.994	0.006
O30.0 Twin pregnancy	0.000	0.994	0.006
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
N18.8 Other chronic renal failure	0.000	0.994	0.005
J98.1 Pulmonary collapse	0.000	0.994	0.006
M89.0 Algoneurodystrophy	0.006	0.994	0.000
Z49.2 Other dialysis	0.000	0.994	0.005
N18.4 Chronic kidney disease, stage 4	0.000	0.995	0.005
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.995	0.005
M89.9 Disorder of bone, unspecified	0.005	0.995	0.000
M89.04 Algoneurodystrophy (Hand)	0.005	0.995	0.000
F20 Schizophrenia	0.000	0.995	0.005
M89 Other disorders of bone	0.005	0.995	0.000
Z60.2 Living alone	0.000	0.995	0.005
L90.0 Lichen sclerosus et atrophicus	0.000	0.995	0.005
J33 Nasal polyp	0.000	0.995	0.005
N19 Unspecified renal failure	0.000	0.995	0.005
M89.96 Disorder of bone, unspecified (Lower leg)	0.005	0.995	0.000
F20.0 Paranoid schizophrenia	0.000	0.995	0.005
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.995	0.005
M89.3 Hypertrophy of bone	0.005	0.995	0.000
I10 Essential (primary) hypertension	0.000	0.995	0.005
M89.09 Algoneurodystrophy (Site unspecified)	0.005	0.995	0.000
K14 Diseases of tongue	0.000	0.995	0.005
R26.1 Paralytic gait	0.000	0.995	0.004
Z57.2 Occupational exposure to dust	0.000	0.995	0.005
M89.03 Algoneurodystrophy (Forearm)	0.004	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.004	0.996	0.000
J33.8 Other polyp of sinus	0.000	0.996	0.004
M89.5 Osteolysis	0.004	0.996	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.004	0.996	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.004	0.996	0.000
M89.08 Algoneurodystrophy (Other)	0.004	0.996	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.004	0.996	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.004	0.996	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.004	0.996	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.004	0.996	0.000
N17-N19 Renal failure	0.000	0.996	0.004
M89.06 Algoneurodystrophy (Lower leg)	0.004	0.996	0.000
R26.0 Ataxic gait	0.000	0.996	0.004
F25 Schizoaffective disorders	0.000	0.996	0.004
Z60 Problems related to social environment	0.000	0.996	0.004
M89.99 Disorder of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.004	0.996	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.004	0.996	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.996	0.004
F20.5 Residual schizophrenia	0.000	0.996	0.004
R26.3 Immobility	0.000	0.996	0.004
M89.55 Osteolysis (Pelvic region and thigh)	0.004	0.996	0.000
F20.8 Other schizophrenia	0.000	0.996	0.004
F20.6 Simple schizophrenia	0.000	0.996	0.004
F20.4 Postschizophrenic depression	0.000	0.996	0.004
F20.3 Undifferentiated schizophrenia	0.000	0.996	0.004
F20.2 Catatonic schizophrenia	0.000	0.996	0.004
F20.1 Hebephrenic schizophrenia	0.000	0.996	0.004
J34.3 Hypertrophy of nasal turbinates	0.000	0.996	0.004
F25.9 Schizoaffective disorder, unspecified	0.000	0.996	0.004
M89.6 Osteopathy after poliomyelitis	0.004	0.996	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.004	0.996	0.000
M89.2 Other disorders of bone development and growth	0.004	0.996	0.000
M89.1 Epiphyseal arrest	0.004	0.996	0.000
D18.0 Haemangioma, any site	0.004	0.996	0.000
Z57 Occupational exposure to risk-factors	0.000	0.996	0.004
N18.2 Chronic kidney disease, stage 2	0.000	0.996	0.004
M89.38 Hypertrophy of bone (Other)	0.004	0.996	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.004	0.996	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.996	0.004
J33.9 Nasal polyp, unspecified	0.000	0.996	0.004
M50.2 Other cervical disk displacement	0.000	0.996	0.004
J33.1 Polypoid sinus degeneration	0.000	0.996	0.004
N18.9 Chronic renal failure, unspecified	0.000	0.996	0.004
M89.39 Hypertrophy of bone (Site unspecified)	0.003	0.996	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.003	0.996	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.003	0.996	0.000
M89.34 Hypertrophy of bone (Hand)	0.003	0.996	0.000
M89.33 Hypertrophy of bone (Forearm)	0.003	0.996	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.003	0.996	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.003	0.996	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.003	0.996	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.996	0.000
K14.5 Plicated tongue	0.000	0.996	0.003
K14.4 Atrophy of tongue papillae	0.000	0.996	0.003
K14.3 Hypertrophy of tongue papillae	0.000	0.996	0.003
K14.2 Median rhomboid glossitis	0.000	0.996	0.003
Z56.6 Other physical and mental strain related to work	0.000	0.996	0.004
Z57.3 Occupational exposure to other air contaminants	0.000	0.996	0.004
C44.5 Skin of trunk	0.004	0.996	0.000
M89.59 Osteolysis (Site unspecified)	0.003	0.997	0.000
M89.58 Osteolysis (Other)	0.003	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.003	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.003	0.997	0.000
M89.54 Osteolysis (Hand)	0.003	0.997	0.000
M89.53 Osteolysis (Forearm)	0.003	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.003	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.003	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
Z56 Problems related to employment and unemployment	0.000	0.997	0.003
K22.0 Achalasia of cardia	0.003	0.997	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.997	0.003
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.997	0.003
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.000	0.997	0.003
L03.8 Cellulitis of other sites	0.000	0.997	0.003
Z60.9 Problem related to social environment, unspecified	0.000	0.997	0.003
K14.6 Glossodynia	0.000	0.997	0.003
F25.8 Other schizoaffective disorders	0.000	0.997	0.003
F25.2 Schizoaffective disorder, mixed type	0.000	0.997	0.003
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.997	0.003
Z60.4 Social exclusion and rejection	0.000	0.997	0.003
Z60.3 Acculturation difficulty	0.000	0.997	0.003
Z60.1 Atypical parenting situation	0.000	0.997	0.003
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
K14.1 Geographic tongue	0.000	0.997	0.003
M89.19 Epiphyseal arrest (Site unspecified)	0.003	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.003	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.003	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.003	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.003	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.003	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.003	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.003	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.003	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.003	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.003	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.003	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.003	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.003	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.003	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.003	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.003	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.003	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.003	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.003	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.003	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.003	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.003	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.003	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.003	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.003	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.003	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.003	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.003	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.003	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.003	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.003	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.003	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.003	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.003	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.003	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.003	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.997	0.003
Z57.8 Occupational exposure to other risk-factors	0.000	0.997	0.003
Z57.7 Occupational exposure to vibration	0.000	0.997	0.003
Z57.6 Occupational exposure to extreme temperature	0.000	0.997	0.003
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.997	0.003
Z57.1 Occupational exposure to radiation	0.000	0.997	0.003
Z57.0 Occupational exposure to noise	0.000	0.997	0.003
Z89.5 Acquired absence of leg at or below knee	0.000	0.997	0.003
Z60.8 Other problems related to social environment	0.000	0.997	0.003
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
Z59 Problems related to housing and economic circumstances	0.000	0.997	0.003
I20.0 Unstable angina	0.000	0.997	0.003
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.997	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.997	0.003
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
Z56.7 Other and unspecified problems related to employment	0.000	0.997	0.003
Z56.5 Uncongenial work	0.000	0.997	0.003
Z56.4 Discord with boss and workmates	0.000	0.997	0.003
Z56.2 Threat of job loss	0.000	0.997	0.003
Z56.1 Change of job	0.000	0.997	0.003
Z56.0 Unemployment, unspecified	0.000	0.997	0.003
Z56.3 Stressful work schedule	0.000	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.997	0.003
Z65 Problems related to other psychosocial circumstances	0.000	0.997	0.003
Z62 Other problems related to upbringing	0.000	0.997	0.003
Z55 Problems related to education and literacy	0.000	0.997	0.003
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
F28 Other nonorganic psychotic disorders	0.000	0.997	0.003
F24 Induced delusional disorder	0.000	0.997	0.003
F21 Schizotypal disorder	0.000	0.997	0.003
Z59.0 Homelessness	0.000	0.997	0.003
Z61 Problems related to negative life events in childhood	0.000	0.997	0.002
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.997	0.003
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.003	0.997	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.997	0.002
Z89 Acquired absence of limb	0.000	0.997	0.003
O30 Multiple gestation	0.000	0.997	0.003
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.997	0.002
Z89.6 Acquired absence of leg above knee	0.000	0.997	0.002
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
Z59.1 Inadequate housing	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
M24.5 Contracture of joint	0.002	0.998	0.000
F22 Persistent delusional disorders	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.000	0.998	0.002
Z59.7 Insufficient social insurance and welfare support	0.000	0.998	0.002
Z59.6 Low income	0.000	0.998	0.002
Z59.5 Extreme poverty	0.000	0.998	0.002
Z59.4 Lack of adequate food	0.000	0.998	0.002
Z59.3 Problems related to living in residential institution	0.000	0.998	0.002
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.998	0.002
Z58 Problems related to physical environment	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.002
Z63 Other problems related to primary support group, including family circumstances	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.002	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.998	0.002
Z55.8 Other problems relating to education and literacy	0.000	0.998	0.002
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.998	0.002
Z55.3 Underachievement in school	0.000	0.998	0.002
Z55.2 Failed examinations	0.000	0.998	0.002
Z55.1 Schooling unavailable and unattainable	0.000	0.998	0.002
Z55.0 Illiteracy and low-level literacy	0.000	0.998	0.002
Z62.9 Problem related to upbringing, unspecified	0.000	0.998	0.002
Z62.8 Other specified problems related to upbringing	0.000	0.998	0.002
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.998	0.002
Z62.5 Other problems related to neglect in upbringing	0.000	0.998	0.002
Z62.4 Emotional neglect of child	0.000	0.998	0.002
Z62.3 Hostility towards and scapegoating of child	0.000	0.998	0.002
Z62.2 Institutional upbringing	0.000	0.998	0.002
Z62.1 Parental overprotection	0.000	0.998	0.002
Z62.0 Inadequate parental supervision and control	0.000	0.998	0.002
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.998	0.002
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.998	0.002
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.998	0.002
Z65.4 Victim of crime and terrorism	0.000	0.998	0.002
Z65.3 Problems related to other legal circumstances	0.000	0.998	0.002
Z65.2 Problems related to release from prison	0.000	0.998	0.002
Z65.1 Imprisonment and other incarceration	0.000	0.998	0.002
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
R49.0 Dysphonia	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.002
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.998	0.002
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.000	0.998	0.002
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.1 Problems related to multiparity	0.000	0.998	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
O30.9 Multiple gestation, unspecified	0.000	0.998	0.002
O30.8 Other multiple gestation	0.000	0.998	0.002
O30.2 Quadruplet pregnancy	0.000	0.998	0.002
O30.1 Triplet pregnancy	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
R07.4 Chest pain, unspecified	0.000	0.998	0.002
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.998	0.002
O03 Spontaneous abortion	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
F29 Unspecified nonorganic psychosis	0.000	0.998	0.002
T87.4 Infection of amputation stump	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
R27 Other lack of coordination	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.002
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
Z58.7 Exposure to tobacco smoke	0.000	0.998	0.002
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.000	0.998	0.002
Z58.6 Inadequate drinking-water supply	0.000	0.998	0.002
Z58.4 Exposure to radiation	0.000	0.998	0.002
Z58.3 Exposure to soil pollution	0.000	0.998	0.002
Z58.2 Exposure to water pollution	0.000	0.998	0.002
Z58.0 Exposure to noise	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.002
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.998	0.002
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.002
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.000	0.998	0.002
Z63.3 Absence of family member	0.000	0.998	0.002
Z63.2 Inadequate family support	0.000	0.998	0.002
Z63.1 Problems in relationship with parents and in-laws	0.000	0.998	0.002
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.002	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.998	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.000	0.998	0.002
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.000	0.998	0.002
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
Z94.0 Kidney transplant status	0.000	0.998	0.002
G83 Other paralytic syndromes	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
O03.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O03.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
G83.9 Paralytic syndrome, unspecified	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
J31.2 Chronic pharyngitis	0.000	0.998	0.002
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.998	0.000
F22.0 Delusional disorder	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
O66 Other obstructed labour	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.000	0.998	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.001
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
X59.3 Sports and athletics area	0.000	0.998	0.002
D18 Haemangioma and lymphangioma, any site	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.998	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.001
Z63.5 Disruption of family by separation and divorce	0.000	0.998	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
G83.5 Locked-in syndrome	0.001	0.998	0.000
G83.3 Monoplegia, unspecified	0.001	0.998	0.000
G83.0 Diplegia of upper limbs	0.001	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.001	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
D41.0 Kidney	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.001	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.998	0.000
S27.6 Injury of pleura	0.001	0.998	0.000
S27.5 Injury of thoracic trachea	0.001	0.998	0.000
S27.4 Injury of bronchus	0.001	0.998	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.001
Z58.1 Exposure to air pollution	0.000	0.998	0.001
S27.8 Injury of other specified intrathoracic organs	0.001	0.998	0.000
S27.1 Traumatic haemothorax	0.001	0.998	0.000
T87.3 Neuroma of amputation stump	0.000	0.998	0.001
S27.0 Traumatic pneumothorax	0.001	0.998	0.000
T87.5 Necrosis of amputation stump	0.000	0.998	0.001
T87.2 Complications of other reattached body part	0.000	0.998	0.001
T87.1 Complications of reattached (part of) lower extremity	0.000	0.998	0.001
T87.0 Complications of reattached (part of) upper extremity	0.000	0.998	0.001
Z50.1 Other physical therapy	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.001
L71.9 Rosacea, unspecified	0.001	0.999	0.000
O66.2 Obstructed labour due to unusually large foetus	0.001	0.999	0.000
G83.2 Monoplegia of upper limb	0.001	0.999	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.999	0.001
O66.9 Obstructed labour, unspecified	0.001	0.999	0.000
O66.8 Other specified obstructed labour	0.001	0.999	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.001	0.999	0.000
O66.1 Obstructed labour due to locked twins	0.001	0.999	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
G83.8 Other specified paralytic syndromes	0.001	0.999	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.999	0.001
Z50 Care involving use of rehabilitation procedures	0.001	0.999	0.000
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.999	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.001	0.999	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
D45 Polycythaemia vera	0.001	0.999	0.000
Z63.4 Disappearance and death of family member	0.000	0.999	0.001
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
D18.1 Lymphangioma, any site	0.001	0.999	0.000
M20.4 Other hammer toe(s) (acquired)	0.001	0.999	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
R07.1 Chest pain on breathing	0.001	0.999	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.999	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.999	0.001
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.999	0.001
O71 Other obstetric trauma	0.001	0.999	0.000
M79.10 Myalgia (Multiple sites)	0.001	0.999	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
D04.7 Skin of lower limb, including hip	0.001	0.999	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.999	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.999	0.001
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
Z50.6 Orthoptic training	0.001	0.999	0.000
Z50.3 Drug rehabilitation	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
J31.0 Chronic rhinitis	0.000	0.999	0.001
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.001	0.999	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.001	0.999	0.000
O64.5 Obstructed labour due to compound presentation	0.001	0.999	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.999	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.999	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.999	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations