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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12403995
log Bayes Factor = 6.45074
Chromosome 1   position 221,921,377  (GRCh37) Explore rs12403995 on Ensembl!
Variant rs12403995 is part of Cluster X0076

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.995 0.005 0.000
O36 Maternal care for other known or suspected foetal problems
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.994 0.006 0.000
Chapter II Neoplasms
0.993 0.007 0.000
O60-O75 Complications of labour and delivery
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.991 0.009 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.990 0.010 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.989 0.011 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.989 0.011 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.988 0.012 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
D68 Other coagulation defects
0.986 0.014 0.000
O36.8 Maternal care for other specified foetal problems
0.983 0.017 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.971 0.029 0.000
O36.5 Maternal care for poor foetal growth
0.969 0.031 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.961 0.039 0.000
J60-J70 Lung diseases due to external agents
0.961 0.039 0.000
J00-J06 Acute upper respiratory infections
0.960 0.040 0.000
D68.8 Other specified coagulation defects
0.958 0.042 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.955 0.045 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.952 0.048 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.946 0.054 0.000
F33 Recurrent depressive disorder
0.944 0.056 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.943 0.057 0.000
F10.0 Acute intoxication
0.942 0.058 0.000
F32 Depressive episode
0.937 0.063 0.000
D60-D64 Aplastic and other anaemias
0.936 0.064 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.936 0.064 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.932 0.068 0.000
S70-S79 Injuries to the hip and thigh
0.931 0.069 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.931 0.069 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.930 0.070 0.000
J09-J18 Influenza and pneumonia
0.926 0.074 0.000
C71 Malignant neoplasm of brain
0.921 0.079 0.000
J06.9 Acute upper respiratory infection, unspecified
0.919 0.081 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.915 0.085 0.000
O72 Postpartum haemorrhage
0.911 0.089 0.000
F10.2 Dependence syndrome
0.910 0.090 0.000
S40-S49 Injuries to the shoulder and upper arm
0.906 0.094 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
J18 Pneumonia, organism unspecified
0.904 0.096 0.000
J18.9 Pneumonia, unspecified
0.900 0.100 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.894 0.106 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.893 0.107 0.000
O85-O92 Complications predominantly related to the puerperium
0.891 0.109 0.000
C51-C58 Malignant neoplasms of female genital organs
0.885 0.115 0.000
S40 Superficial injury of shoulder and upper arm
0.885 0.115 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.884 0.116 0.000
D61 Other aplastic anaemias
0.881 0.119 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.881 0.119 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.880 0.120 0.000
F30 Manic episode
0.879 0.121 0.000
O42 Premature rupture of membranes
0.878 0.122 0.000
S79 Other and unspecified injuries of hip and thigh
0.878 0.122 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.875 0.125 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.872 0.128 0.000
S20-S29 Injuries to the thorax
0.872 0.128 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.867 0.133 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.867 0.133 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.867 0.133 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.862 0.138 0.000
Chapter XXII Codes for special purposes
0.861 0.139 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.858 0.142 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.850 0.150 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.846 0.154 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.844 0.156 0.000
S90-S99 Injuries to the ankle and foot
0.843 0.157 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.842 0.158 0.000
S20 Superficial injury of thorax
0.842 0.158 0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.842 0.158 0.000
C92 Myeloid leukaemia
0.840 0.160 0.000
J04 Acute laryngitis and tracheitis
0.838 0.162 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.838 0.162 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.835 0.165 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.834 0.166 0.000
O36.6 Maternal care for excessive foetal growth
0.834 0.166 0.000
F60-F69 Disorders of adult personality and behaviour
0.834 0.166 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.832 0.167 0.000
D68.2 Hereditary deficiency of other clotting factors
0.832 0.168 0.000
O63 Long labour
0.832 0.168 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.832 0.168 0.000
C81 Hodgkin's disease
0.831 0.169 0.000
Q80-Q89 Other congenital malformations
0.831 0.169 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.831 0.169 0.000
D68.4 Acquired coagulation factor deficiency
0.830 0.170 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.828 0.172 0.000
S79.9 Unspecified injury of hip and thigh
0.826 0.174 0.000
D61.9 Aplastic anaemia, unspecified
0.825 0.175 0.000
F33.9 Recurrent depressive disorder, unspecified
0.825 0.175 0.000
O34.4 Maternal care for other abnormalities of cervix
0.823 0.177 0.000
O62 Abnormalities of forces of labour
0.816 0.184 0.000
O44 Placenta praevia
0.814 0.186 0.000
S20.2 Contusion of thorax
0.812 0.188 0.000
C71.9 Brain, unspecified
0.812 0.188 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.811 0.189 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.810 0.190 0.000
O41 Other disorders of amniotic fluid and membranes
0.809 0.191 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.807 0.193 0.000
F10.4 Withdrawal state with delirium
0.806 0.194 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.804 0.196 0.000
T00-T07 Injuries involving multiple body regions
0.804 0.196 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.803 0.197 0.000
D68.9 Coagulation defect, unspecified
0.803 0.197 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.799 0.201 0.000
J00 Acute nasopharyngitis [common cold]
0.799 0.201 0.000
O90 Complications of the puerperium, not elsewhere classified
0.794 0.206 0.000
C79 Secondary malignant neoplasm of other sites
0.793 0.207 0.000
C91 Lymphoid leukaemia
0.791 0.209 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
O72.1 Other immediate postpartum haemorrhage
0.789 0.211 0.000
C71.2 Temporal lobe
0.788 0.212 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.787 0.213 0.000
C80 Malignant neoplasm without specification of site
0.786 0.214 0.000
T79-T79 Certain early complications of trauma
0.785 0.215 0.000
F10.5 Psychotic disorder
0.784 0.216 0.000
O63.0 Prolonged first stage (of labour)
0.782 0.218 0.000
C82.0 Small cleaved cell, follicular
0.782 0.218 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.782 0.218 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.782 0.218 0.000
T14 Injury of unspecified body region
0.782 0.218 0.000
D68.5 Primary Thrombophilia
0.781 0.218 0.000
J11 Influenza, virus not identified
0.781 0.219 0.000
F39 Unspecified mood [affective] disorder
0.780 0.220 0.000
D63.0 Anaemia in neoplastic disease
0.779 0.221 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.778 0.222 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.777 0.223 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.776 0.224 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.776 0.224 0.000
C71.0 Cerebrum, except lobes and ventricles
0.775 0.225 0.000
F10.9 Unspecified mental and behavioural disorder
0.774 0.226 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.773 0.227 0.000
D55-D59 Haemolytic anaemias
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
O73 Retained placenta and membranes, without haemorrhage
0.770 0.230 0.000
C92.0 Acute myeloid leukaemia
0.770 0.230 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.767 0.233 0.000
J69 Pneumonitis due to solids and liquids
0.765 0.235 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.764 0.236 0.000
C56 Malignant neoplasm of ovary
0.763 0.237 0.000
O00-O08 Pregnancy with abortive outcome
0.763 0.237 0.000
F11 Mental and behavioural disorders due to use of opioids
0.762 0.238 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.762 0.238 0.000
F30.0 Hypomania
0.760 0.240 0.000
S60-S69 Injuries to the wrist and hand
0.754 0.246 0.000
O72.0 Third-stage haemorrhage
0.754 0.246 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.753 0.247 0.000
D50-D53 Nutritional anaemias
0.753 0.247 0.000
S92 Fracture of foot, except ankle
0.753 0.247 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.750 0.250 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.749 0.251 0.000
O45 Premature separation of placenta [abruptio placentae]
0.748 0.252 0.000
J86 Pyothorax
0.745 0.255 0.000
U88 Agent resistant to multiple antibiotics
0.745 0.255 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.745 0.255 0.000
F34 Persistent mood [affective] disorders
0.744 0.256 0.000
D66 Hereditary factor VIII deficiency
0.744 0.256 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.743 0.257 0.000
O36.1 Maternal care for other isoimmunisation
0.743 0.257 0.000
T45.0 Antiallergic and antiemetic drugs
0.742 0.258 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.741 0.259 0.000
Q85 Phakomatoses, not elsewhere classified
0.741 0.259 0.000
D70 Agranulocytosis
0.740 0.260 0.000
F10.1 Harmful use
0.740 0.260 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.738 0.262 0.000
O75.0 Maternal distress during labour and delivery
0.738 0.262 0.000
T11 Other injuries of upper limb, level unspecified
0.738 0.262 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.737 0.263 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.737 0.263 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.736 0.264 0.000
Q50-Q56 Congenital malformations of genital organs
0.734 0.265 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.734 0.266 0.000
S40.0 Contusion of shoulder and upper arm
0.734 0.266 0.000
D68.6 Other Thrombophilia
0.733 0.267 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.733 0.267 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.731 0.269 0.000
O33 Maternal care for known or suspected disproportion
0.730 0.270 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.730 0.270 0.000
O87 Venous complications in the puerperium
0.727 0.273 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.727 0.273 0.000
O36.4 Maternal care for intra-uterine death
0.723 0.277 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.723 0.277 0.000
C76.2 Abdomen
0.723 0.277 0.000
T46.1 Calcium-channel blockers
0.722 0.278 0.000
J70 Respiratory conditions due to other external agents
0.721 0.279 0.000
C95 Leukaemia of unspecified cell type
0.720 0.280 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.719 0.281 0.000
T14.0 Superficial injury of unspecified body region
0.718 0.282 0.000
F10.3 Withdrawal state
0.718 0.282 0.000
C78.2 Secondary malignant neoplasm of pleura
0.718 0.282 0.000
F30.2 Mania with psychotic symptoms
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C71.1 Frontal lobe
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
O31 Complications specific to multiple gestation
0.716 0.284 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F60 Specific personality disorders
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.713 0.287 0.000
O36.2 Maternal care for hydrops foetalis
0.713 0.287 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.713 0.287 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.713 0.287 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.713 0.287 0.000
C71.4 Occipital lobe
0.711 0.289 0.000
O74 Complications of anaesthesia during labour and delivery
0.711 0.289 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.711 0.289 0.000
O60 Preterm delivery
0.711 0.289 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.711 0.289 0.000
D67 Hereditary factor IX deficiency
0.710 0.290 0.000
T43.9 Psychotropic drug, unspecified
0.709 0.291 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.709 0.291 0.000
T43.6 Psychostimulants with abuse potential
0.709 0.291 0.000
C51 Malignant neoplasm of vulva
0.709 0.291 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.709 0.291 0.000
F10.8 Other mental and behavioural disorders
0.708 0.291 0.000
F10.7 Residual and late-onset psychotic disorder
0.708 0.291 0.000
O04 Medical abortion
0.707 0.293 0.000
D68.1 Hereditary factor XI deficiency
0.707 0.293 0.000
C12 Malignant neoplasm of pyriform sinus
0.706 0.294 0.000
D61.1 Drug-induced aplastic anaemia
0.704 0.296 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.704 0.296 0.000
D51 Vitamin B12 deficiency anaemia
0.704 0.296 0.000
F31 Bipolar affective disorder
0.704 0.296 0.000
O16 Unspecified maternal hypertension
0.703 0.297 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.703 0.297 0.000
C94 Other leukaemias of specified cell type
0.703 0.297 0.000
C93 Monocytic leukaemia
0.703 0.297 0.000
C86 Other specified types of T/NK-cell lymphoma
0.703 0.297 0.000
O75.8 Other specified complications of labour and delivery
0.703 0.297 0.000
O62.0 Primary inadequate contractions
0.702 0.298 0.000
C81.9 Hodgkin's disease, unspecified
0.700 0.299 0.000
C82.3 Follicular lymphoma grade IIIa
0.699 0.301 0.000
Chapter IX Diseases of the circulatory system
0.699 0.301 0.000
S79.8 Other specified injuries of hip and thigh
0.698 0.302 0.000
S70 Superficial injury of hip and thigh
0.697 0.303 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.697 0.303 0.000
I10-I15 Hypertensive diseases
0.696 0.304 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.696 0.304 0.000
O34.6 Maternal care for abnormality of vagina
0.696 0.304 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.696 0.304 0.000
O34.3 Maternal care for cervical incompetence
0.696 0.304 0.000
O34.0 Maternal care for congenital malformation of uterus
0.696 0.304 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.696 0.304 0.000
F10.6 Amnesic syndrome
0.695 0.305 0.000
C82.2 Large cell, follicular
0.695 0.305 0.000
J04.1 Acute tracheitis
0.695 0.305 0.000
J04.0 Acute laryngitis
0.694 0.306 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.694 0.306 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.692 0.308 0.000
S90 Superficial injury of ankle and foot
0.691 0.309 0.000
C71.3 Parietal lobe
0.691 0.309 0.000
C71.8 Overlapping lesion of brain
0.690 0.310 0.000
J01 Acute sinusitis
0.689 0.311 0.000
I12 Hypertensive renal disease
0.689 0.311 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.689 0.311 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.689 0.311 0.000
J66 Airway disease due to specific organic dust
0.689 0.311 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.689 0.311 0.000
J62 Pneumoconiosis due to dust containing silica
0.689 0.311 0.000
J65 Pneumoconiosis associated with tuberculosis
0.689 0.311 0.000
J64 Unspecified pneumoconiosis
0.689 0.311 0.000
J60 Coalworker's pneumoconiosis
0.689 0.311 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.688 0.312 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.687 0.313 0.000
I12.0 Hypertensive renal disease with renal failure
0.685 0.315 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.685 0.315 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.685 0.315 0.000
O64.5 Obstructed labour due to compound presentation
0.685 0.315 0.000
O64.4 Obstructed labour due to shoulder presentation
0.685 0.315 0.000
O64.3 Obstructed labour due to brow presentation
0.685 0.315 0.000
O64.2 Obstructed labour due to face presentation
0.685 0.315 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.684 0.316 0.000
C82.6 Cutaneous follicle centre lymphoma
0.682 0.317 0.000
C82.5 Diffuse follicle centre lymphoma
0.682 0.317 0.000
C82.4 Follicular lymphoma grade IIIb
0.682 0.317 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.682 0.318 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.682 0.318 0.000
Q89 Other congenital malformations, not elsewhere classified
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.678 0.322 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.677 0.322 0.000
F33.8 Other recurrent depressive disorders
0.677 0.323 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.677 0.323 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.676 0.324 0.000
C70 Malignant neoplasm of meninges
0.676 0.324 0.000
S71 Open wound of hip and thigh
0.676 0.324 0.000
T00 Superficial injuries involving multiple body regions
0.675 0.324 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.674 0.326 0.000
O30 Multiple gestation
0.674 0.326 0.000
O64.1 Obstructed labour due to breech presentation
0.674 0.326 0.000
C04 Malignant neoplasm of floor of mouth
0.674 0.326 0.000
C52 Malignant neoplasm of vagina
0.674 0.326 0.000
F32.8 Other depressive episodes
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.672 0.328 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.671 0.329 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.671 0.329 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.671 0.329 0.000
J06.0 Acute laryngopharyngitis
0.671 0.329 0.000
O44.1 Placenta praevia with haemorrhage
0.671 0.329 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.669 0.331 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.668 0.332 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.668 0.332 0.000
T46.7 Peripheral vasodilators
0.668 0.332 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.668 0.332 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.668 0.332 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.668 0.332 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.668 0.332 0.000
S78 Traumatic amputation of hip and thigh
0.667 0.332 0.000
S77 Crushing injury of hip and thigh
0.667 0.332 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.667 0.332 0.000
S75 Injury of blood vessels at hip and thigh level
0.667 0.332 0.000
S74 Injury of nerves at hip and thigh level
0.667 0.332 0.000
S41 Open wound of shoulder and upper arm
0.667 0.333 0.000
T50.4 Drugs affecting uric acid metabolism
0.667 0.333 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.666 0.334 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.666 0.334 0.000
C91.0 Acute lymphoblastic leukaemia
0.665 0.335 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.664 0.336 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.664 0.336 0.000
J12 Viral pneumonia, not elsewhere classified
0.664 0.336 0.000
J09 Influenza due to certain identified influenza virus
0.664 0.336 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.663 0.337 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.663 0.337 0.000
T45.5 Anticoagulants
0.663 0.337 0.000
C71.7 Brain stem
0.661 0.339 0.000
C71.6 Cerebellum
0.661 0.339 0.000
C71.5 Cerebral ventricle
0.661 0.339 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.661 0.339 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.660 0.340 0.000
S92.0 Fracture of calcaneus
0.659 0.341 0.000
D69 Purpura and other haemorrhagic conditions
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.656 0.344 0.000
O85 Puerperal sepsis
0.656 0.344 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.656 0.344 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.656 0.344 0.000
J67.2 Bird fancier's lung
0.655 0.345 0.000
S21 Open wound of thorax
0.655 0.345 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.654 0.346 0.000
O42.9 Premature rupture of membranes, unspecified
0.654 0.346 0.000
O72.3 Postpartum coagulation defects
0.653 0.347 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.653 0.347 0.000
S69 Other and unspecified injuries of wrist and hand
0.652 0.348 0.000
J15.9 Bacterial pneumonia, unspecified
0.651 0.349 0.000
Chapter XXI Factors influencing health status and contact with health services
0.651 0.349 0.000
I95 Hypotension
0.651 0.349 0.000
C76.1 Thorax
0.650 0.350 0.000
S10 Superficial injury of neck
0.650 0.350 0.000
S48 Traumatic amputation of shoulder and upper arm
0.650 0.350 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.650 0.350 0.000
S44 Injury of nerves at shoulder and upper arm level
0.650 0.350 0.000
S47 Crushing injury of shoulder and upper arm
0.650 0.350 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.649 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.649 0.351 0.000
O61 Failed induction of labour
0.649 0.351 0.000
O71 Other obstetric trauma
0.649 0.351 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.649 0.351 0.000
J18.2 Hypostatic pneumonia, unspecified
0.648 0.352 0.000
D68.0 Von Willebrand's disease
0.647 0.353 0.000
O90.9 Complication of the puerperium, unspecified
0.647 0.353 0.000
Q83 Congenital malformations of breast
0.646 0.354 0.000
S60 Superficial injury of wrist and hand
0.646 0.354 0.000
O04.4 Incomplete, without complication
0.645 0.355 0.000
T39.0 Salicylates
0.644 0.356 0.000
J18.8 Other pneumonia, organism unspecified
0.643 0.357 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.642 0.358 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.641 0.359 0.000
J10 Influenza due to identified influenza virus
0.641 0.359 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.640 0.360 0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.640 0.360 0.000
J67.7 Air-conditioner and humidifier lung
0.640 0.360 0.000
J67.6 Maple-bark-stripper's lung
0.640 0.360 0.000
J67.5 Mushroom-worker's lung
0.640 0.360 0.000
J67.4 Maltworker's lung
0.640 0.360 0.000
J67.3 Suberosis
0.640 0.360 0.000
J67.1 Bagassosis
0.640 0.360 0.000
J67.0 Farmer's lung
0.640 0.360 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.640 0.360 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.639 0.360 0.000
O91 Infections of breast associated with childbirth
0.639 0.361 0.000
O89 Complications of anaesthesia during the puerperium
0.639 0.361 0.000
O88 Obstetric embolism
0.639 0.361 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.639 0.361 0.000
C81.1 Nodular sclerosis
0.637 0.363 0.000
I95.1 Orthostatic hypotension
0.635 0.365 0.000
C58 Malignant neoplasm of placenta
0.635 0.365 0.000
S40.7 Multiple superficial injuries of shoulder and upper arm
0.634 0.366 0.000
T09 Other injuries of spine and trunk, level unspecified
0.634 0.366 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.634 0.366 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.634 0.366 0.000
T12 Fracture of lower limb, level unspecified
0.634 0.366 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.634 0.366 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.634 0.366 0.000
T10 Fracture of upper limb, level unspecified
0.634 0.366 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.634 0.366 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.634 0.366 0.000
T08 Fracture of spine, level unspecified
0.634 0.366 0.000
T36 Poisoning by systemic antibiotics
0.633 0.367 0.000
D73 Diseases of spleen
0.633 0.367 0.000
C88 Malignant immunoproliferative diseases
0.632 0.368 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.632 0.368 0.000
D61.8 Other specified aplastic anaemias
0.632 0.368 0.000
D61.3 Idiopathic aplastic anaemia
0.632 0.368 0.000
D61.2 Aplastic anaemia due to other external agents
0.632 0.368 0.000
D61.0 Constitutional aplastic anaemia
0.632 0.368 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.632 0.368 0.000
J20-J22 Other acute lower respiratory infections
0.631 0.369 0.000
F19.1 Harmful use
0.630 0.370 0.000
J86.9 Pyothorax without fistula
0.630 0.370 0.000
F30.8 Other manic episodes
0.630 0.370 0.000
F30.1 Mania without psychotic symptoms
0.630 0.370 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.630 0.370 0.000
S79.7 Multiple injuries of hip and thigh
0.630 0.370 0.000
F32.0 Mild depressive episode
0.629 0.370 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.628 0.372 0.000
J15.4 Pneumonia due to other streptococci
0.628 0.372 0.000
O75.9 Complication of labour and delivery, unspecified
0.627 0.373 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.627 0.373 0.000
O75.4 Other complications of obstetric surgery and procedures
0.627 0.373 0.000
O75.3 Other infection during labour
0.627 0.373 0.000
O75.1 Shock during or following labour and delivery
0.627 0.373 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.626 0.374 0.000
F19.2 Dependence syndrome
0.626 0.374 0.000
T50.8 Diagnostic agents
0.625 0.374 0.000
T50.7 Analeptics and opioid receptor antagonists
0.625 0.374 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.625 0.374 0.000
T50.5 Appetite depressants
0.625 0.374 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.625 0.374 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.625 0.374 0.000
T50.1 Loop [high-ceiling] diuretics
0.625 0.374 0.000
T50.0 Mineralocorticoids and their antagonists
0.625 0.374 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.625 0.375 0.000
S26 Injury of heart
0.625 0.375 0.000
S25 Injury of blood vessels of thorax
0.625 0.375 0.000
S24 Injury of nerves and spinal cord at thorax level
0.625 0.375 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.625 0.375 0.000
J69.0 Pneumonitis due to food and vomit
0.625 0.375 0.000
C11 Malignant neoplasm of nasopharynx
0.625 0.375 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.624 0.375 0.000
Q54 Hypospadias
0.624 0.376 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.624 0.376 0.000
O41.0 Oligohydramnios
0.624 0.376 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.624 0.376 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.624 0.376 0.000
T11.1 Open wound of upper limb, level unspecified
0.622 0.378 0.000
I11 Hypertensive heart disease
0.622 0.378 0.000
O15 Eclampsia
0.622 0.378 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.622 0.378 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.622 0.378 0.000
C85.0 Lymphosarcoma
0.622 0.378 0.000
O63.9 Long labour, unspecified
0.621 0.379 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.620 0.380 0.000
F15.1 Harmful use
0.620 0.380 0.000
C78.7 Secondary malignant neoplasm of liver
0.620 0.380 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.619 0.381 0.000
F64 Gender identity disorders
0.618 0.382 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.618 0.382 0.000
T45.8 Other primarily systemic and haematological agents
0.618 0.382 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.618 0.382 0.000
T45.6 Fibrinolysis-affecting drugs
0.618 0.382 0.000
T45.4 Iron and its compounds
0.618 0.382 0.000
T45.3 Enzymes, not elsewhere classified
0.618 0.382 0.000
T45.2 Vitamins, not elsewhere classified
0.618 0.382 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.618 0.382 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.618 0.382 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.614 0.386 0.000
J86.0 Pyothorax with fistula
0.613 0.387 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.612 0.388 0.000
Q25 Congenital malformations of great arteries
0.612 0.388 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.611 0.389 0.000
O40 Polyhydramnios
0.611 0.389 0.000
F30.9 Manic episode, unspecified
0.611 0.389 0.000
U89 Agent resistant to other and unspecified antibiotics
0.610 0.389 0.000
J95-J99 Other diseases of the respiratory system
0.610 0.390 0.000
F60.3 Emotionally unstable personality disorder
0.610 0.390 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.610 0.390 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.610 0.390 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.610 0.390 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.610 0.390 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.610 0.390 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.610 0.390 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.610 0.390 0.000
T44.0 Anticholinesterase agents
0.610 0.390 0.000
D56 Thalassaemia
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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