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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12440014
log Bayes Factor = 17.3365
Chromosome 15   position 78,926,726  (GRCh37) Explore rs12440014 on Ensembl!
Variant rs12440014 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
J43 Emphysema
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.001 0.999
I71 Aortic aneurysm and dissection
0.000 0.001 0.999
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.001 0.999
I73 Other peripheral vascular diseases
0.000 0.004 0.996
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.006 0.994
I73.9 Peripheral vascular disease, unspecified
0.000 0.009 0.991
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.015 0.985
I77 Other disorders of arteries and arterioles
0.000 0.048 0.952
I73.0 Raynaud's syndrome
0.000 0.059 0.941
I70 Atherosclerosis
0.000 0.077 0.923
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.086 0.914
J90-J94 Other diseases of pleura
0.000 0.096 0.904
Chapter X Diseases of the respiratory system
0.000 0.096 0.904
J42 Unspecified chronic bronchitis
0.000 0.101 0.899
J92 Pleural plaque
0.000 0.107 0.893
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.109 0.891
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.113 0.887
J93 Pneumothorax
0.000 0.123 0.877
J92.9 Pleural plaque without asbestos
0.000 0.132 0.868
I72 Other aneurysm
0.000 0.134 0.866
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.145 0.855
J93.1 Other spontaneous pneumothorax
0.000 0.148 0.852
J60-J70 Lung diseases due to external agents
0.000 0.180 0.820
J92.0 Pleural plaque with presence of asbestos
0.000 0.188 0.812
I77.0 Arteriovenous fistula, acquired
0.000 0.196 0.804
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.215 0.785
I74 Arterial embolism and thrombosis
0.000 0.226 0.774
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.230 0.770
J43.2 Centrilobular emphysema
0.000 0.237 0.763
J95-J99 Other diseases of the respiratory system
0.000 0.250 0.750
I72.8 Aneurysm of other specified arteries
0.000 0.256 0.744
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.257 0.743
I77.1 Stricture of artery
0.000 0.257 0.743
I77.2 Rupture of artery
0.000 0.260 0.740
J41 Simple and mucopurulent chronic bronchitis
0.000 0.261 0.738
I72.0 Aneurysm of carotid artery
0.000 0.262 0.738
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.284 0.716
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.284 0.716
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.284 0.716
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.284 0.716
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.286 0.714
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.292 0.708
J93.9 Pneumothorax, unspecified
0.000 0.303 0.697
J86 Pyothorax
0.000 0.305 0.695
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.309 0.691
J90 Pleural effusion, not elsewhere classified
0.000 0.310 0.690
I77.5 Necrosis of artery
0.000 0.318 0.682
I77.4 Coeliac artery compression syndrome
0.000 0.318 0.682
I72.9 Aneurysm of unspecified site
0.000 0.334 0.666
J60 Coalworker's pneumoconiosis
0.000 0.337 0.663
I70.9 Generalised and unspecified atherosclerosis
0.000 0.338 0.661
I70.8 Atherosclerosis of other arteries
0.000 0.338 0.661
I71.0 Dissection of aorta [any part]
0.000 0.339 0.661
J91 Pleural effusion in conditions classified elsewhere
0.000 0.347 0.653
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.349 0.651
I70.0 Atherosclerosis of aorta
0.000 0.351 0.649
I77.8 Other specified disorders of arteries and arterioles
0.000 0.352 0.648
J98 Other respiratory disorders
0.000 0.354 0.646
J86.9 Pyothorax without fistula
0.000 0.356 0.644
J93.0 Spontaneous tension pneumothorax
0.000 0.364 0.636
J43.8 Other emphysema
0.000 0.373 0.627
I78 Diseases of capillaries
0.000 0.378 0.622
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.379 0.621
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.379 0.621
I72.1 Aneurysm of artery of upper extremity
0.000 0.379 0.621
J98.1 Pulmonary collapse
0.000 0.396 0.604
I72.3 Aneurysm of iliac artery
0.000 0.403 0.597
J93.8 Other pneumothorax
0.000 0.406 0.594
J94 Other pleural conditions
0.000 0.412 0.588
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.412 0.588
J66 Airway disease due to specific organic dust
0.000 0.412 0.588
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.412 0.588
J62 Pneumoconiosis due to dust containing silica
0.000 0.412 0.588
J65 Pneumoconiosis associated with tuberculosis
0.000 0.412 0.588
J98.9 Respiratory disorder, unspecified
0.000 0.417 0.583
I74.8 Embolism and thrombosis of other arteries
0.000 0.417 0.582
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.428 0.572
I72.4 Aneurysm of artery of lower extremity
0.000 0.432 0.568
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.434 0.566
J64 Unspecified pneumoconiosis
0.000 0.440 0.560
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.445 0.555
J70 Respiratory conditions due to other external agents
0.000 0.447 0.553
I73.8 Other specified peripheral vascular diseases
0.000 0.448 0.551
J41.0 Simple chronic bronchitis
0.000 0.448 0.551
J40 Bronchitis, not specified as acute or chronic
0.000 0.453 0.547
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.454 0.546
I74.5 Embolism and thrombosis of iliac artery
0.000 0.457 0.543
I70.1 Atherosclerosis of renal artery
0.000 0.458 0.541
I77.3 Arterial fibromuscular dysplasia
0.000 0.459 0.541
J96 Respiratory failure, not elsewhere classified
0.000 0.462 0.538
I77.6 Arteritis, unspecified
0.000 0.463 0.537
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.470 0.530
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.470 0.529
J41.1 Mucopurulent chronic bronchitis
0.000 0.470 0.529
I72.2 Aneurysm of renal artery
0.000 0.470 0.529
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.475 0.524
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.481 0.519
I79.1 Aortitis in diseases classified elsewhere
0.000 0.492 0.507
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.492 0.507
J85 Abscess of lung and mediastinum
0.000 0.506 0.494
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.507 0.492
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.508 0.492
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.509 0.490
J98.4 Other disorders of lung
0.000 0.510 0.490
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.512 0.488
J86.0 Pyothorax with fistula
0.000 0.513 0.487
J94.8 Other specified pleural conditions
0.000 0.518 0.482
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.526 0.474
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.526 0.474
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.526 0.474
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.526 0.474
J69 Pneumonitis due to solids and liquids
0.000 0.526 0.473
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.527 0.473
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.534 0.465
J98.3 Compensatory emphysema
0.000 0.537 0.463
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.547 0.453
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.548 0.452
J98.2 Interstitial emphysema
0.000 0.550 0.450
I78.9 Disease of capillaries, unspecified
0.000 0.554 0.446
J99.0 Rheumatoid lung disease
0.000 0.564 0.436
J46 Status asthmaticus
0.000 0.575 0.425
J94.1 Fibrothorax
0.000 0.575 0.425
J94.9 Pleural condition, unspecified
0.000 0.578 0.422
J94.0 Chylous effusion
0.000 0.578 0.422
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.578 0.421
J62.0 Pneumoconiosis due to talc dust
0.000 0.578 0.421
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.578 0.421
J63.5 Stannosis
0.000 0.578 0.421
J63.4 Siderosis
0.000 0.578 0.421
J63.3 Graphite fibrosis (of lung)
0.000 0.578 0.421
J63.2 Berylliosis
0.000 0.578 0.421
J63.1 Bauxite fibrosis (of lung)
0.000 0.578 0.421
J63.0 Aluminosis (of lung)
0.000 0.578 0.421
J66.8 Airway disease due to other specific organic dusts
0.000 0.578 0.421
J66.2 Cannabinosis
0.000 0.578 0.421
J66.1 Flax-dresser's disease
0.000 0.578 0.421
J66.0 Byssinosis
0.000 0.578 0.421
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.578 0.421
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.578 0.421
I78.8 Other diseases of capillaries
0.000 0.583 0.417
J98.8 Other specified respiratory disorders
0.000 0.603 0.397
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.603 0.396
J70.8 Respiratory conditions due to other specified external agents
0.000 0.603 0.396
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.603 0.396
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.603 0.396
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.603 0.396
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.603 0.396
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.611 0.388
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.613 0.386
J95.8 Other postprocedural respiratory disorders
0.000 0.613 0.387
J96.9 Respiratory failure, unspecified
0.000 0.614 0.386
J96.1 Chronic respiratory failure
0.000 0.614 0.386
J96.0 Acute respiratory failure
0.000 0.614 0.386
J85.1 Abscess of lung with pneumonia
0.000 0.618 0.382
J20-J22 Other acute lower respiratory infections
0.000 0.625 0.375
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.628 0.372
J67.7 Air-conditioner and humidifier lung
0.000 0.628 0.372
J67.6 Maple-bark-stripper's lung
0.000 0.628 0.372
J67.5 Mushroom-worker's lung
0.000 0.628 0.372
J67.4 Maltworker's lung
0.000 0.628 0.372
J67.3 Suberosis
0.000 0.628 0.372
J67.1 Bagassosis
0.000 0.628 0.372
J67.0 Farmer's lung
0.000 0.628 0.372
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.633 0.367
J98.6 Disorders of diaphragm
0.000 0.637 0.363
J84 Other interstitial pulmonary diseases
0.000 0.638 0.361
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.639 0.361
J85.3 Abscess of mediastinum
0.000 0.646 0.354
J85.0 Gangrene and necrosis of lung
0.000 0.646 0.354
J69.8 Pneumonitis due to other solids and liquids
0.000 0.647 0.353
J95.5 Postprocedural subglottic stenosis
0.000 0.647 0.353
J95.4 Mendelson's syndrome
0.000 0.647 0.353
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.647 0.353
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.647 0.353
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.647 0.353
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.657 0.342
J69.1 Pneumonitis due to oils and essences
0.000 0.660 0.340
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.661 0.339
J67.2 Bird fancier's lung
0.000 0.661 0.339
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.669 0.331
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.674 0.325
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.675 0.325
I78.1 Naevus, nonneoplastic
0.000 0.682 0.318
J00-J06 Acute upper respiratory infections
0.000 0.692 0.308
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.703 0.297
J20 Acute bronchitis
0.000 0.703 0.297
J84.8 Other specified interstitial pulmonary diseases
0.000 0.718 0.282
J95.0 Tracheostomy malfunction
0.000 0.719 0.280
J96.09 Acute respiratory failure; Type unspecified
0.000 0.723 0.277
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.723 0.277
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.723 0.277
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.723 0.277
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.723 0.277
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.723 0.277
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.723 0.277
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.723 0.277
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.723 0.277
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.731 0.268
J84.0 Alveolar and parietoalveolar conditions
0.000 0.741 0.259
J85.2 Abscess of lung without pneumonia
0.001 0.752 0.247
J00 Acute nasopharyngitis [common cold]
0.000 0.760 0.240
J20.8 Acute bronchitis due to other specified organisms
0.000 0.764 0.236
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.770 0.229
J21 Acute bronchiolitis
0.000 0.773 0.227
J94.2 Haemothorax
0.001 0.774 0.225
J20.9 Acute bronchitis, unspecified
0.000 0.781 0.219
J20.7 Acute bronchitis due to echovirus
0.000 0.787 0.213
J20.6 Acute bronchitis due to rhinovirus
0.000 0.787 0.213
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.787 0.213
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.787 0.213
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.787 0.213
J20.2 Acute bronchitis due to streptococcus
0.000 0.787 0.213
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.787 0.213
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.787 0.213
J04 Acute laryngitis and tracheitis
0.000 0.795 0.205
J02 Acute pharyngitis
0.000 0.796 0.204
J69.0 Pneumonitis due to food and vomit
0.000 0.803 0.197
J45 Asthma
0.000 0.814 0.185
J05.1 Acute epiglottitis
0.000 0.827 0.173
J01 Acute sinusitis
0.000 0.828 0.172
J82 Pulmonary eosinophilia, not elsewhere classified
0.001 0.831 0.168
J05.0 Acute obstructive laryngitis [croup]
0.000 0.835 0.165
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.837 0.163
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.837 0.163
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.837 0.163
J03 Acute tonsillitis
0.000 0.845 0.155
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.847 0.153
J04.1 Acute tracheitis
0.000 0.850 0.149
C34.1 Upper lobe, bronchus or lung
0.000 0.852 0.148
J04.2 Acute laryngotracheitis
0.000 0.853 0.147
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.854 0.146
J02.9 Acute pharyngitis, unspecified
0.000 0.855 0.145
J45.8 Mixed asthma
0.000 0.867 0.133
J09-J18 Influenza and pneumonia
0.000 0.868 0.132
J02.0 Streptococcal pharyngitis
0.000 0.869 0.131
J04.0 Acute laryngitis
0.000 0.873 0.127
J45.1 Nonallergic asthma
0.000 0.874 0.126
J01.0 Acute maxillary sinusitis
0.000 0.875 0.125
C34 Malignant neoplasm of bronchus and lung
0.000 0.875 0.125
J01.8 Other acute sinusitis
0.000 0.876 0.123
J01.4 Acute pansinusitis
0.000 0.876 0.123
J01.3 Acute sphenoidal sinusitis
0.000 0.876 0.123
J01.1 Acute frontal sinusitis
0.000 0.876 0.123
J21.9 Acute bronchiolitis, unspecified
0.001 0.879 0.121
C34.9 Bronchus or lung, unspecified
0.000 0.884 0.116
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.888 0.111
J03.0 Streptococcal tonsillitis
0.000 0.888 0.111
J81 Pulmonary oedema
0.001 0.889 0.110
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.890 0.110
J06.0 Acute laryngopharyngitis
0.000 0.890 0.110
J01.2 Acute ethmoidal sinusitis
0.000 0.891 0.109
C34.3 Lower lobe, bronchus or lung
0.000 0.898 0.102
C34.2 Middle lobe, bronchus or lung
0.000 0.898 0.102
J10 Influenza due to identified influenza virus
0.000 0.904 0.096
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.905 0.095
J09 Influenza due to certain identified influenza virus
0.000 0.905 0.095
J01.9 Acute sinusitis, unspecified
0.000 0.906 0.094
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.907 0.093
J47 Bronchiectasis
0.000 0.910 0.090
J17 Pneumonia in diseases classified elsewhere
0.000 0.911 0.089
J12 Viral pneumonia, not elsewhere classified
0.000 0.917 0.083
J14 Pneumonia due to Haemophilus influenzae
0.000 0.918 0.082
C34.8 Overlapping lesion of bronchus and lung
0.000 0.919 0.081
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.921 0.079
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.924 0.075
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.930 0.070
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.930 0.070
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.931 0.069
J80 Adult respiratory distress syndrome
0.004 0.931 0.065
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.931 0.068
J16.0 Chlamydial pneumonia
0.000 0.931 0.068
J11 Influenza, virus not identified
0.000 0.934 0.065
J15.4 Pneumonia due to other streptococci
0.000 0.935 0.065
N64.5 Other signs and symptoms in breast
0.064 0.936 0.000
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.936 0.064
C34.0 Main bronchus
0.000 0.937 0.063
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.062 0.938 0.000
J17.3 Pneumonia in parasitic diseases
0.000 0.940 0.060
J12.8 Other viral pneumonia
0.000 0.940 0.059
J12.3 Human metapneumovirus pneumonia
0.000 0.940 0.059
J12.2 Parainfluenza virus pneumonia
0.000 0.940 0.059
J12.1 Respiratory syncytial virus pneumonia
0.000 0.940 0.059
J12.0 Adenoviral pneumonia
0.000 0.940 0.059
J15.5 Pneumonia due to Escherichia coli
0.000 0.941 0.059
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.941 0.059
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.941 0.058
N64 Other disorders of breast
0.059 0.941 0.000
J15.2 Pneumonia due to staphylococcus
0.000 0.942 0.058
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.943 0.057
J15.3 Pneumonia due to streptococcus, group B
0.000 0.943 0.056
J15.9 Bacterial pneumonia, unspecified
0.000 0.944 0.055
J15.8 Other bacterial pneumonia
0.000 0.945 0.055
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.055 0.945 0.000
N64.8 Other specified disorders of breast
0.054 0.946 0.000
N64.4 Mastodynia
0.051 0.949 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.951 0.049
N64.9 Disorder of breast, unspecified
0.048 0.952 0.000
J17.2 Pneumonia in mycoses
0.000 0.952 0.047
J11.8 Influenza with other manifestations, virus not identified
0.000 0.953 0.047
J12.9 Viral pneumonia, unspecified
0.000 0.953 0.047
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.046 0.954 0.000
J03.9 Acute tonsillitis, unspecified
0.000 0.954 0.046
T43.2 Other and unspecified antidepressants
0.045 0.955 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.044 0.956 0.000
N64.1 Fat necrosis of breast
0.044 0.956 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.956 0.044
C32 Malignant neoplasm of larynx
0.000 0.956 0.044
T36-T50 Poisoning by drugs, medicaments and biological substances
0.044 0.956 0.000
N64.3 Galactorrhoea not associated with childbirth
0.042 0.958 0.000
N64.2 Atrophy of breast
0.042 0.958 0.000
N64.0 Fissure and fistula of nipple
0.042 0.958 0.000
T42.0 Hydantoin derivatives
0.042 0.958 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.959 0.041
J11.0 Influenza with pneumonia, virus not identified
0.000 0.959 0.041
T42.4 Benzodiazepines
0.040 0.960 0.000
T42.1 Iminostilbenes
0.040 0.960 0.000
J45.0 Predominantly allergic asthma
0.000 0.960 0.040
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.039 0.960 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.039 0.960 0.000
T42.3 Barbiturates
0.039 0.960 0.000
T42.2 Succinimides and oxazolidinediones
0.039 0.960 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.039 0.961 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.037 0.963 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.037 0.963 0.000
C32.0 Glottis
0.000 0.963 0.037
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.036 0.963 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.965 0.035
C31 Malignant neoplasm of accessory sinuses
0.000 0.965 0.035
C33 Malignant neoplasm of trachea
0.000 0.965 0.035
C32.9 Larynx, unspecified
0.000 0.965 0.035
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.965 0.035
C67.2 Lateral wall of bladder
0.000 0.965 0.035
C67 Malignant neoplasm of bladder
0.000 0.966 0.034
C32.1 Supraglottis
0.000 0.966 0.034
T43.5 Other and unspecified antipsychotics and neuroleptics
0.034 0.966 0.000
C67.6 Ureteric orifice
0.000 0.967 0.033
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.033 0.967 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.033 0.967 0.000
T45.0 Antiallergic and antiemetic drugs
0.032 0.967 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.032 0.968 0.000
C85.1 B-cell lymphoma, unspecified
0.032 0.968 0.000
C67.1 Dome of bladder
0.000 0.968 0.032
C67.3 Anterior wall of bladder
0.000 0.968 0.032
T43.9 Psychotropic drug, unspecified
0.032 0.968 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.032 0.968 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.032 0.968 0.000
C32.8 Overlapping lesion of larynx
0.000 0.968 0.031
C32.3 Laryngeal cartilage
0.000 0.968 0.031
C32.2 Subglottis
0.000 0.968 0.031
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.032 0.968 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.031 0.968 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.031 0.968 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.032 0.968 0.000
E11.2 With renal complications
0.000 0.969 0.031
J15.1 Pneumonia due to Pseudomonas
0.000 0.969 0.031
E11 Non-insulin-dependent diabetes mellitus
0.000 0.969 0.031
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.969 0.031
Chapter IX Diseases of the circulatory system
0.000 0.969 0.031
T46.5 Other antihypertensive drugs, not elsewhere classified
0.031 0.969 0.000
I60 Subarachnoid haemorrhage
0.000 0.969 0.031
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.031 0.969 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.031 0.969 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.031 0.969 0.000
E11.3 With ophthalmic complications
0.000 0.970 0.030
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.970 0.030
J18 Pneumonia, organism unspecified
0.000 0.970 0.030
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.030 0.970 0.000
I60-I69 Cerebrovascular diseases
0.000 0.970 0.030
J11.1 Influenza with other respiratory manifestations, virus not identified
0.000 0.970 0.030
I27.9 Pulmonary heart disease, unspecified
0.000 0.970 0.030
T43.3 Phenothiazine antipsychotics and neuroleptics
0.029 0.971 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.029 0.971 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.971 0.029
T40.4 Other synthetic narcotics
0.028 0.972 0.000
T38.1 Thyroid hormones and substitutes
0.028 0.972 0.000
I27 Other pulmonary heart diseases
0.000 0.972 0.028
T36 Poisoning by systemic antibiotics
0.028 0.972 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.972 0.028
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.972 0.028
E11.4 With neurological complications
0.000 0.972 0.028
T43.4 Butyrophenone and thioxanthene neuroleptics
0.028 0.972 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.028 0.972 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.027 0.973 0.000
T47.0 Histamine H(2)-receptor antagonists
0.027 0.973 0.000
C67.4 Posterior wall of bladder
0.000 0.973 0.027
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.027 0.973 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.027 0.973 0.000
T46.7 Peripheral vasodilators
0.027 0.973 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.027 0.973 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.027 0.973 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.027 0.973 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.027 0.973 0.000
T45.8 Other primarily systemic and haematological agents
0.027 0.973 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.027 0.973 0.000
T45.6 Fibrinolysis-affecting drugs
0.027 0.973 0.000
T45.4 Iron and its compounds
0.027 0.973 0.000
T45.3 Enzymes, not elsewhere classified
0.027 0.973 0.000
I60.8 Other subarachnoid haemorrhage
0.000 0.973 0.027
T45.2 Vitamins, not elsewhere classified
0.027 0.973 0.000
E11.5 With peripheral circulatory complications
0.000 0.974 0.026
T38.9 Other and unspecified hormone antagonists
0.026 0.974 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.026 0.974 0.000
T38.7 Androgens and anabolic congeners
0.026 0.974 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.026 0.974 0.000
T38.5 Other oestrogens and progestogens
0.026 0.974 0.000
T38.4 Oral contraceptives
0.026 0.974 0.000
T38.2 Antithyroid drugs
0.026 0.974 0.000
T38.0 Glucocorticoids and synthetic analogues
0.026 0.974 0.000
C67.5 Bladder neck
0.000 0.974 0.026
T43.6 Psychostimulants with abuse potential
0.025 0.974 0.000
E11.8 With unspecified complications
0.000 0.974 0.026
C31.9 Accessory sinus, unspecified
0.000 0.974 0.025
C31.8 Overlapping lesion of accessory sinuses
0.000 0.974 0.025
C31.3 Sphenoidal sinus
0.000 0.974 0.025
C31.2 Frontal sinus
0.000 0.974 0.025
C31.1 Ethmoidal sinus
0.000 0.974 0.025
C31.0 Maxillary sinus
0.000 0.974 0.025
C39.9 Ill-defined sites within the respiratory system
0.000 0.974 0.025
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.000 0.974 0.025
C39.0 Upper respiratory tract, part unspecified
0.000 0.974 0.025
C30.1 Middle ear
0.000 0.974 0.025
E11.0 With coma
0.000 0.975 0.025
C30.0 Nasal cavity
0.000 0.975 0.025
C67.8 Overlapping lesion of bladder
0.000 0.975 0.025
T48.6 Antiasthmatics, not elsewhere classified
0.025 0.975 0.000
T47.2 Stimulant laxatives
0.025 0.975 0.000
C67.7 Urachus
0.000 0.975 0.025
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.975 0.025
I69 Sequelae of cerebrovascular disease
0.000 0.975 0.025
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.975 0.024
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.024 0.976 0.000
T48.5 Anti-common-cold drugs
0.024 0.976 0.000
T48.4 Expectorants
0.024 0.976 0.000
T48.3 Antitussives
0.024 0.976 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.024 0.976 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.024 0.976 0.000
T48.0 Oxytocic drugs
0.024 0.976 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.023 0.976 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.023 0.976 0.000
T47.7 Emetics
0.023 0.976 0.000
T47.6 Antidiarrhoeal drugs
0.023 0.976 0.000
T47.5 Digestants
0.023 0.976 0.000
T47.4 Other laxatives
0.023 0.976 0.000
T47.3 Saline and osmotic laxatives
0.023 0.976 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.023 0.977 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.977 0.023
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.023 0.977 0.000
T40.8 Lysergide [LSD]
0.023 0.977 0.000
T40.7 Cannabis (derivatives)
0.023 0.977 0.000
T40.3 Methadone
0.023 0.977 0.000
T40.1 Heroin
0.023 0.977 0.000
T40.0 Opium
0.023 0.977 0.000
T41.5 Therapeutic gases
0.023 0.977 0.000
T41.4 Anaesthetic, unspecified
0.023 0.977 0.000
T41.3 Local anaesthetics
0.023 0.977 0.000
T41.2 Other and unspecified general anaesthetics
0.023 0.977 0.000
T41.1 Intravenous anaesthetics
0.023 0.977 0.000
T41.0 Inhaled anaesthetics
0.023 0.977 0.000
T49.9 Topical agent, unspecified
0.023 0.977 0.000
T49.8 Other topical agents
0.023 0.977 0.000
T49.7 Dental drugs, topically applied
0.023 0.977 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.023 0.977 0.000
T49.5 Ophthalmological drugs and preparations
0.023 0.977 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.023 0.977 0.000
T49.3 Emollients, demulcents and protectants
0.023 0.977 0.000
T49.2 Local astringents and local detergents
0.023 0.977 0.000
T49.1 Antipruritics
0.023 0.977 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.023 0.977 0.000
T40.5 Cocaine
0.023 0.977 0.000
C85.0 Lymphosarcoma
0.023 0.977 0.000
T40.6 Other and unspecified narcotics
0.023 0.977 0.000
E11.7 With multiple complications
0.000 0.977 0.022
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.000 0.977 0.022
C38.3 Mediastinum, part unspecified
0.000 0.977 0.022
C38.2 Posterior mediastinum
0.000 0.977 0.022
C38.1 Anterior mediastinum
0.000 0.977 0.022
C38.0 Heart
0.000 0.977 0.022
I00-I02 Acute rheumatic fever
0.000 0.978 0.022
I67 Other cerebrovascular diseases
0.000 0.978 0.022
T45.5 Anticoagulants
0.022 0.978 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.978 0.022
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.978 0.022
I67.9 Cerebrovascular disease, unspecified
0.000 0.978 0.022
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.978 0.022
I69.3 Sequelae of cerebral infarction
0.000 0.978 0.022
J18.2 Hypostatic pneumonia, unspecified
0.000 0.978 0.022
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.978 0.022

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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