TreeWAS – Variant ID: rs12450239

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.982	0.018
Z98.0 Intestinal bypass and anastomosis status	0.000	0.986	0.014
Z98 Other postsurgical states	0.000	0.986	0.014
Z98.1 Arthrodesis status	0.000	0.986	0.014
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.986	0.014
Z98.8 Other specified postsurgical states	0.000	0.989	0.011
D37.7 Other digestive organs	0.009	0.991	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.008	0.992	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.007	0.993	0.000
C78.2 Secondary malignant neoplasm of pleura	0.007	0.993	0.000
Y84.0 Cardiac catheterisation	0.000	0.994	0.006
R82.9 Other and unspecified abnormal finding in urine	0.000	0.996	0.004
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.996	0.004
N99.0 Postprocedural renal failure	0.004	0.996	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.996	0.004
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
T31.0 Burns involving less than 10% of body surface	0.000	0.996	0.004
N49.2 Inflammatory disorders of scrotum	0.004	0.996	0.000
C67.2 Lateral wall of bladder	0.000	0.996	0.004
R25.2 Cramp and spasm	0.000	0.996	0.004
Z97.5 Presence of (intra-uterine) contraceptive device	0.004	0.996	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
R25.3 Fasciculation	0.000	0.996	0.004
O20.0 Threatened abortion	0.003	0.997	0.000
R25 Abnormal involuntary movements	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.997	0.003
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.997	0.003
C09.9 Tonsil, unspecified	0.003	0.997	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.003	0.997	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.997	0.003
J44 Other chronic obstructive pulmonary disease	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K92.8 Other specified diseases of digestive system	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
R25.0 Abnormal head movements	0.000	0.997	0.003
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
G50.0 Trigeminal neuralgia	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.997	0.002
M96.5 Postradiation scoliosis	0.000	0.997	0.002
M96.4 Postsurgical lordosis	0.000	0.997	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.997	0.002
M96.2 Postradiation kyphosis	0.000	0.997	0.002
Q65 Congenital deformities of hip	0.002	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
K92 Other diseases of digestive system	0.000	0.998	0.002
C04.9 Floor of mouth, unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
K31.5 Obstruction of duodenum	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
N81.9 Female genital prolapse, unspecified	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
C03.1 Lower gum	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
T31 Burns classified according to extent of body surface involved	0.000	0.998	0.002
C04 Malignant neoplasm of floor of mouth	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.998	0.002
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
C09.8 Overlapping lesion of tonsil	0.002	0.998	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.998	0.000
C09.0 Tonsillar fossa	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
C03 Malignant neoplasm of gum	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
O92.1 Cracked nipple associated with childbirth	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
C04.8 Overlapping lesion of floor of mouth	0.002	0.998	0.000
C04.1 Lateral floor of mouth	0.002	0.998	0.000
C04.0 Anterior floor of mouth	0.002	0.998	0.000
T31.9 Burns involving 90% or more of body surface	0.000	0.998	0.002
T31.8 Burns involving 80-89% of body surface	0.000	0.998	0.002
T31.7 Burns involving 70-79% of body surface	0.000	0.998	0.002
T31.6 Burns involving 60-69% of body surface	0.000	0.998	0.002
T31.5 Burns involving 50-59% of body surface	0.000	0.998	0.002
T31.4 Burns involving 40-49% of body surface	0.000	0.998	0.002
T31.3 Burns involving 30-39% of body surface	0.000	0.998	0.002
T31.2 Burns involving 20-29% of body surface	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.998	0.002
J44.9 Chronic obstructive pulmonary disease, unspecified	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C02.1 Border of tongue	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
C03.9 Gum, unspecified	0.002	0.998	0.000
C03.0 Upper gum	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
G50.1 Atypical facial pain	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
R54 Senility	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.998	0.002
R82.3 Haemoglobinuria	0.000	0.998	0.002
R82.2 Biliuria	0.000	0.998	0.002
R82.1 Myoglobinuria	0.000	0.998	0.002
R82.0 Chyluria	0.000	0.998	0.002
T31.1 Burns involving 10-19% of body surface	0.000	0.998	0.001
C02.4 Lingual tonsil	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.000	0.998	0.002
O22.3 Deep phlebothrombosis in pregnancy	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.001	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.001	0.998	0.000
C02.0 Dorsal surface of tongue	0.001	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.002
R82.4 Acetonuria	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.001	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
T36.0 Penicillins	0.002	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
D32.0 Cerebral meninges	0.000	0.998	0.002
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q96 Turner's syndrome	0.001	0.998	0.000
C02.2 Ventral surface of tongue	0.001	0.998	0.000
O86.8 Other specified puerperal infections	0.001	0.998	0.000
C00 Malignant neoplasm of lip	0.001	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
A40.8 Other streptococcal septicaemia	0.002	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.001	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.001	0.998	0.000
C11 Malignant neoplasm of nasopharynx	0.001	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.998	0.000
J43.2 Centrilobular emphysema	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.998	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.001	0.998	0.000
C05 Malignant neoplasm of palate	0.001	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.001	0.998	0.000
G50 Disorders of trigeminal nerve	0.000	0.998	0.002
Q90 Down's syndrome	0.001	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.998	0.000
C10.9 Oropharynx, unspecified	0.001	0.998	0.000
C10.8 Overlapping lesion of oropharynx	0.001	0.998	0.000
C10.4 Branchial cleft	0.001	0.998	0.000
C10.3 Posterior wall of oropharynx	0.001	0.998	0.000
C10.2 Lateral wall of oropharynx	0.001	0.998	0.000
C10.1 Anterior surface of epiglottis	0.001	0.998	0.000
C10.0 Vallecula	0.001	0.998	0.000
D32.1 Spinal meninges	0.000	0.998	0.001
C12 Malignant neoplasm of pyriform sinus	0.001	0.998	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.001	0.998	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.001	0.999	0.000
C14.2 Waldeyer's ring	0.001	0.999	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.999	0.000
Q24 Other congenital malformations of heart	0.001	0.999	0.000
R64 Cachexia	0.001	0.999	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
C90.2 Plasmacytoma, extramedullary	0.000	0.999	0.001
Q90.9 Down's syndrome, unspecified	0.001	0.999	0.000
S61.8 Open wound of other parts of wrist and hand	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.999	0.000
C14.0 Pharynx, unspecified	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.999	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.999	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.999	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.999	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.999	0.000
C13.8 Overlapping lesion of hypopharynx	0.001	0.999	0.000
C13.2 Posterior wall of hypopharynx	0.001	0.999	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.001	0.999	0.000
C13.0 Postcricoid region	0.001	0.999	0.000
C67.3 Anterior wall of bladder	0.000	0.999	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.999	0.001
Q82.2 Mastocytosis	0.001	0.999	0.000
Q96.8 Other variants of Turner's syndrome	0.001	0.999	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.001	0.999	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.001	0.999	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.001	0.999	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.001	0.999	0.000
Q96.0 Karyotype 45,X	0.001	0.999	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.001	0.999	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.001	0.999	0.000
Q98.7 Male with sex chromosome mosaicism	0.001	0.999	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.001	0.999	0.000
Q98.5 Karyotype 47,XYY	0.001	0.999	0.000
Q98.3 Other male with 46,XX karyotype	0.001	0.999	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.001	0.999	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.001	0.999	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
C00.9 Lip, unspecified	0.001	0.999	0.000
C00.8 Overlapping lesion of lip	0.001	0.999	0.000
C00.6 Commissure of lip	0.001	0.999	0.000
C00.5 Lip, unspecified, inner aspect	0.001	0.999	0.000
C00.4 Lower lip, inner aspect	0.001	0.999	0.000
C00.3 Upper lip, inner aspect	0.001	0.999	0.000
C00.2 External lip, unspecified	0.001	0.999	0.000
C00.1 External lower lip	0.001	0.999	0.000
C11.8 Overlapping lesion of nasopharynx	0.001	0.999	0.000
C11.3 Anterior wall of nasopharynx	0.001	0.999	0.000
C11.2 Lateral wall of nasopharynx	0.001	0.999	0.000
C11.1 Posterior wall of nasopharynx	0.001	0.999	0.000
C11.0 Superior wall of nasopharynx	0.001	0.999	0.000
K07.2 Anomalies of dental arch relationship	0.001	0.999	0.000
Q99.9 Chromosomal abnormality, unspecified	0.001	0.999	0.000
Q99.2 Fragile X chromosome	0.001	0.999	0.000
Q99.1 46,XX true hermaphrodite	0.001	0.999	0.000
Q99.0 Chimera 46,XX/46,XY	0.001	0.999	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.001	0.999	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.999	0.001
O22.9 Venous complication in pregnancy, unspecified	0.001	0.999	0.000
O22.8 Other venous complications in pregnancy	0.001	0.999	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.999	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.999	0.000
O22.1 Genital varices in pregnancy	0.001	0.999	0.000
O86.3 Other genito-urinary tract infections following delivery	0.001	0.999	0.000
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
S01.1 Open wound of eyelid and periocular area	0.001	0.999	0.000
C05.8 Overlapping lesion of palate	0.001	0.999	0.000
C05.2 Uvula	0.001	0.999	0.000
C05.0 Hard palate	0.001	0.999	0.000
C08.8 Overlapping lesion of major salivary glands	0.001	0.999	0.000
C08.1 Sublingual gland	0.001	0.999	0.000
G50.8 Other disorders of trigeminal nerve	0.000	0.999	0.001
M48.0 Spinal stenosis	0.000	0.999	0.001
D32 Benign neoplasm of meninges	0.000	0.999	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
A09.9 Gastroenteritis and colitis of unspecified origin	0.000	0.999	0.001
D37.2 Small intestine	0.001	0.999	0.000
Q90.2 Trisomy 21, translocation	0.001	0.999	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.001	0.999	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.001	0.999	0.000
D45 Polycythaemia vera	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
D39.7 Other female genital organs	0.001	0.999	0.000
G24.9 Dystonia, unspecified	0.001	0.999	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.001	0.999	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.001	0.999	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.001	0.999	0.000
Q24.6 Congenital heart block	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.001	0.999	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.999	0.001
S60.9 Superficial injury of wrist and hand, unspecified	0.001	0.999	0.000
Z71.8 Other specified counselling	0.001	0.999	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
C13.9 Hypopharynx, unspecified	0.001	0.999	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.000	0.999	0.001
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
C67.5 Bladder neck	0.000	0.999	0.001
O86.2 Urinary tract infection following delivery	0.001	0.999	0.000
Q91.7 Patau's syndrome, unspecified	0.001	0.999	0.000
Q91.6 Trisomy 13, translocation	0.001	0.999	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.001	0.999	0.000
Q91.3 Edwards' syndrome, unspecified	0.001	0.999	0.000
Q91.2 Trisomy 18, translocation	0.001	0.999	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.001	0.999	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.001	0.999	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.001	0.999	0.000
Q92.7 Triploidy and polyploidy	0.001	0.999	0.000
Q92.6 Extra marker chromosomes	0.001	0.999	0.000
Q92.5 Duplications with other complex rearrangements	0.001	0.999	0.000
Q92.4 Duplications seen only at prometaphase	0.001	0.999	0.000
Q92.3 Minor partial trisomy	0.001	0.999	0.000
Q92.2 Major partial trisomy	0.001	0.999	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.001	0.999	0.000
Q93.9 Deletion from autosomes, unspecified	0.001	0.999	0.000
Q93.8 Other deletions from the autosomes	0.001	0.999	0.000
Q93.7 Deletions with other complex rearrangements	0.001	0.999	0.000
Q93.6 Deletions seen only at prometaphase	0.001	0.999	0.000
Q93.5 Other deletions of part of a chromosome	0.001	0.999	0.000
Q93.4 Deletion of short arm of chromosome 5	0.001	0.999	0.000
Q93.3 Deletion of short arm of chromosome 4	0.001	0.999	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.001	0.999	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.001	0.999	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.001	0.999	0.000
Q95.8 Other balanced rearrangements and structural markers	0.001	0.999	0.000
Q95.5 Individuals with autosomal fragile site	0.001	0.999	0.000
Q95.4 Individuals with marker heterochromatin	0.001	0.999	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.001	0.999	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.001	0.999	0.000
Q95.1 Chromosome inversion in normal individual	0.001	0.999	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.001	0.999	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.001	0.999	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.001	0.999	0.000
Q97.3 Female with 46,XY karyotype	0.001	0.999	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations