TreeWAS – Variant ID: rs12457254

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.020	0.980	0.000
K12.1 Other forms of stomatitis	0.018	0.982	0.000
K12 Stomatitis and related lesions	0.016	0.984	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.014	0.986	0.000
K11 Diseases of salivary glands	0.013	0.987	0.000
K12.2 Cellulitis and abscess of mouth	0.012	0.988	0.000
K01 Embedded and impacted teeth	0.012	0.988	0.000
C34 Malignant neoplasm of bronchus and lung	0.012	0.988	0.000
K07 Dentofacial anomalies [including malocclusion]	0.012	0.988	0.000
K12.0 Recurrent oral aphthae	0.011	0.989	0.000
K12.3 Oral mucositis (ulcerative)	0.011	0.989	0.000
K10 Other diseases of jaws	0.011	0.989	0.000
K11.5 Sialolithiasis	0.011	0.989	0.000
K04 Diseases of pulp and periapical tissues	0.011	0.989	0.000
K14 Diseases of tongue	0.011	0.989	0.000
K09 Cysts of oral region, not elsewhere classified	0.011	0.989	0.000
K13 Other diseases of lip and oral mucosa	0.011	0.989	0.000
K05 Gingivitis and periodontal diseases	0.011	0.989	0.000
K01.1 Impacted teeth	0.011	0.989	0.000
K11.7 Disturbances of salivary secretion	0.011	0.989	0.000
K11.1 Hypertrophy of salivary gland	0.010	0.990	0.000
K08.3 Retained dental root	0.010	0.990	0.000
K08 Other disorders of teeth and supporting structures	0.010	0.990	0.000
K07.3 Anomalies of tooth position	0.010	0.990	0.000
K03 Other diseases of hard tissues of teeth	0.010	0.990	0.000
K11.8 Other diseases of salivary glands	0.010	0.990	0.000
K14.0 Glossitis	0.010	0.990	0.000
C34.3 Lower lobe, bronchus or lung	0.010	0.990	0.000
K04.5 Chronic apical periodontitis	0.010	0.990	0.000
K11.6 Mucocele of salivary gland	0.010	0.990	0.000
K11.9 Disease of salivary gland, unspecified	0.010	0.990	0.000
H33.0 Retinal detachment with retinal break	0.000	0.990	0.010
K07.1 Anomalies of jaw-cranial base relationship	0.010	0.990	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.010	0.990	0.000
K11.4 Fistula of salivary gland	0.009	0.990	0.000
K11.3 Abscess of salivary gland	0.009	0.990	0.000
K11.0 Atrophy of salivary gland	0.009	0.990	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.009	0.991	0.000
K00 Disorders of tooth development and eruption	0.009	0.991	0.000
C34.2 Middle lobe, bronchus or lung	0.009	0.991	0.000
K05.1 Chronic gingivitis	0.009	0.991	0.000
K10.2 Inflammatory conditions of jaws	0.009	0.991	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.009	0.991	0.000
K01.0 Embedded teeth	0.009	0.991	0.000
H33.2 Serous retinal detachment	0.000	0.991	0.009
K13.0 Diseases of lips	0.009	0.991	0.000
C34.8 Overlapping lesion of bronchus and lung	0.009	0.991	0.000
K07.9 Dentofacial anomaly, unspecified	0.009	0.991	0.000
K07.8 Other dentofacial anomalies	0.009	0.991	0.000
K07.5 Dentofacial functional abnormalities	0.009	0.991	0.000
K07.4 Malocclusion, unspecified	0.009	0.991	0.000
K07.2 Anomalies of dental arch relationship	0.009	0.991	0.000
K07.0 Major anomalies of jaw size	0.009	0.991	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.009	0.991	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.008	0.991	0.000
K14.9 Disease of tongue, unspecified	0.008	0.992	0.000
K04.6 Periapical abscess with sinus	0.008	0.992	0.000
K09.0 Developmental odontogenic cysts	0.008	0.992	0.000
K11.2 Sialoadenitis	0.008	0.992	0.000
C34.0 Main bronchus	0.008	0.992	0.000
K10.9 Disease of jaws, unspecified	0.008	0.992	0.000
K10.3 Alveolitis of jaws	0.008	0.992	0.000
K10.1 Giant cell granuloma, central	0.008	0.992	0.000
K10.0 Developmental disorders of jaws	0.008	0.992	0.000
K04.3 Abnormal hard tissue formation in pulp	0.008	0.992	0.000
K04.2 Pulp degeneration	0.008	0.992	0.000
K04.1 Necrosis of pulp	0.008	0.992	0.000
K04.0 Pulpitis	0.008	0.992	0.000
K09.9 Cyst of oral region, unspecified	0.008	0.992	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.008	0.992	0.000
K14.6 Glossodynia	0.008	0.992	0.000
K14.5 Plicated tongue	0.008	0.992	0.000
K14.4 Atrophy of tongue papillae	0.008	0.992	0.000
K14.3 Hypertrophy of tongue papillae	0.008	0.992	0.000
K14.2 Median rhomboid glossitis	0.008	0.992	0.000
K14.1 Geographic tongue	0.008	0.992	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.008	0.992	0.000
K13.5 Oral submucous fibrosis	0.008	0.992	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.008	0.992	0.000
K13.3 Hairy leukoplakia	0.008	0.992	0.000
K13.1 Cheek and lip biting	0.008	0.992	0.000
K05.2 Acute periodontitis	0.008	0.992	0.000
K05.6 Periodontal disease, unspecified	0.008	0.992	0.000
K05.5 Other periodontal diseases	0.008	0.992	0.000
K05.4 Periodontosis	0.008	0.992	0.000
K05.0 Acute gingivitis	0.008	0.992	0.000
K10.8 Other specified diseases of jaws	0.008	0.992	0.000
H33 Retinal detachments and breaks	0.000	0.992	0.008
K08.0 Exfoliation of teeth due to systemic causes	0.007	0.992	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.007	0.992	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.007	0.992	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.007	0.992	0.000
K03.6 Deposits [accretions] on teeth	0.007	0.992	0.000
K03.5 Ankylosis of teeth	0.007	0.992	0.000
K03.4 Hypercementosis	0.007	0.992	0.000
K03.3 Pathological resorption of teeth	0.007	0.992	0.000
K03.2 Erosion of teeth	0.007	0.992	0.000
K03.1 Abrasion of teeth	0.007	0.992	0.000
K03.0 Excessive attrition of teeth	0.007	0.992	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.007	0.992	0.000
K07.6 Temporomandibular joint disorders	0.007	0.993	0.000
K00.9 Disorder of tooth development, unspecified	0.007	0.993	0.000
K00.8 Other disorders of tooth development	0.007	0.993	0.000
K00.7 Teething syndrome	0.007	0.993	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.007	0.993	0.000
K00.4 Disturbances in tooth formation	0.007	0.993	0.000
K00.3 Mottled teeth	0.007	0.993	0.000
K00.2 Abnormalities of size and form of teeth	0.007	0.993	0.000
K00.1 Supernumerary teeth	0.007	0.993	0.000
K00.0 Anodontia	0.007	0.993	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.007	0.993	0.000
K09.2 Other cysts of jaw	0.007	0.993	0.000
K05.3 Chronic periodontitis	0.007	0.993	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.007	0.993	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.007	0.993	0.000
K06.1 Gingival enlargement	0.007	0.993	0.000
K06.0 Gingival recession	0.007	0.993	0.000
K04.8 Radicular cyst	0.007	0.993	0.000
C34.1 Upper lobe, bronchus or lung	0.007	0.993	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.006	0.993	0.000
K02 Dental caries	0.006	0.994	0.000
K00.6 Disturbances in tooth eruption	0.006	0.994	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.006	0.994	0.000
K04.7 Periapical abscess without sinus	0.006	0.994	0.000
K05.22 Aggressive periodontitis, generalized	0.006	0.994	0.000
H33.4 Traction detachment of retina	0.000	0.994	0.006
H33.1 Retinoschisis and retinal cysts	0.000	0.994	0.006
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.005	0.994	0.000
H33.5 Other retinal detachments	0.000	0.994	0.005
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.005	0.995	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.005	0.995	0.000
K02.5 Caries with pulp exposure	0.005	0.995	0.000
K02.4 Odontoclasia	0.005	0.995	0.000
K02.3 Arrested dental caries	0.005	0.995	0.000
K02.2 Caries of cementum	0.005	0.995	0.000
K02.1 Caries of dentin	0.005	0.995	0.000
K02.0 Caries limited to enamel	0.005	0.995	0.000
K14.8 Other diseases of tongue	0.004	0.995	0.000
H61.2 Impacted cerumen	0.005	0.995	0.000
H61 Other disorders of external ear	0.004	0.996	0.000
K02.8 Other dental caries	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.004	0.996	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.996	0.004
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.004	0.996	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.004	0.996	0.000
C31 Malignant neoplasm of accessory sinuses	0.004	0.996	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.004	0.996	0.000
C37 Malignant neoplasm of thymus	0.004	0.996	0.000
C33 Malignant neoplasm of trachea	0.004	0.996	0.000
Z95.1 Presence of aortocoronary bypass graft	0.004	0.996	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.003	0.996	0.000
C32 Malignant neoplasm of larynx	0.004	0.996	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.004	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.003	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.000	0.997	0.003
C32.9 Larynx, unspecified	0.003	0.997	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.997	0.003
C30.1 Middle ear	0.003	0.997	0.000
C30.0 Nasal cavity	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.003	0.997	0.000
C31.8 Overlapping lesion of accessory sinuses	0.003	0.997	0.000
C31.3 Sphenoidal sinus	0.003	0.997	0.000
C31.2 Frontal sinus	0.003	0.997	0.000
C31.1 Ethmoidal sinus	0.003	0.997	0.000
C31.0 Maxillary sinus	0.003	0.997	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.003	0.997	0.000
C38.4 Pleura	0.003	0.997	0.000
C38.3 Mediastinum, part unspecified	0.003	0.997	0.000
C38.2 Posterior mediastinum	0.003	0.997	0.000
C38.1 Anterior mediastinum	0.003	0.997	0.000
C38.0 Heart	0.003	0.997	0.000
C39.9 Ill-defined sites within the respiratory system	0.003	0.997	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.003	0.997	0.000
C39.0 Upper respiratory tract, part unspecified	0.003	0.997	0.000
C32.8 Overlapping lesion of larynx	0.003	0.997	0.000
C32.3 Laryngeal cartilage	0.003	0.997	0.000
C32.2 Subglottis	0.003	0.997	0.000
C32.1 Supraglottis	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.000	0.997	0.003
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.997	0.003
H61.0 Perichondritis of external ear	0.003	0.997	0.000
L72.1 Trichilemmal cyst	0.000	0.997	0.003
H60-H62 Diseases of external ear	0.003	0.997	0.000
Z95.4 Presence of other heart-valve replacement	0.003	0.997	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
C32.0 Glottis	0.002	0.997	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.997	0.003
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
F52.2 Failure of genital response	0.003	0.997	0.000
H02.8 Other specified disorders of eyelid	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
Z87.0 Personal history of diseases of the respiratory system	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.998	0.002
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.998	0.002
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.002
K02.9 Dental caries, unspecified	0.002	0.998	0.000
K86 Other diseases of pancreas	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.998	0.002
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.998	0.002
H30 Chorioretinal inflammation	0.000	0.998	0.002
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
H31 Other disorders of choroid	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.001	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
K86.8 Other specified diseases of pancreas	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.002	0.998	0.000
R02 Gangrene, not elsewhere classified	0.002	0.998	0.000
H02.4 Ptosis of eyelid	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.001	0.998	0.000
H73.1 Chronic myringitis	0.001	0.998	0.000
H73.0 Acute myringitis	0.001	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.001	0.998	0.000
K76.9 Liver disease, unspecified	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.002	0.998	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.998	0.001
H66.9 Otitis media, unspecified	0.001	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.001
N48.8 Other specified disorders of penis	0.002	0.998	0.000
Z93.2 Ileostomy status	0.000	0.998	0.002
B00.1 Herpesviral vesicular dermatitis	0.001	0.998	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.998	0.001
H30.8 Other chorioretinal inflammations	0.000	0.998	0.001
H30.2 Posterior cyclitis	0.000	0.998	0.001
H30.1 Disseminated chorioretinal inflammation	0.000	0.998	0.001
H30.0 Focal chorioretinal inflammation	0.000	0.998	0.001
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.998	0.001
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
S92.4 Fracture of great toe	0.001	0.998	0.000
N63 Unspecified lump in breast	0.000	0.998	0.002
H31.9 Disorder of choroid, unspecified	0.000	0.998	0.001
H31.8 Other specified disorders of choroid	0.000	0.998	0.001
H31.4 Choroidal detachment	0.000	0.998	0.001
H31.3 Choroidal haemorrhage and rupture	0.000	0.998	0.001
H31.2 Hereditary choroidal dystrophy	0.000	0.998	0.001
H31.1 Choroidal degeneration	0.000	0.998	0.001
H36.0 Diabetic retinopathy	0.000	0.998	0.001
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.999	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
H31.0 Chorioretinal scars	0.000	0.999	0.001
O72.1 Other immediate postpartum haemorrhage	0.000	0.999	0.001
H66 Suppurative and unspecified otitis media	0.001	0.999	0.000
H34 Retinal vascular occlusions	0.000	0.999	0.001
R74 Abnormal serum enzyme levels	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I21.4 Acute subendocardial myocardial infarction	0.001	0.999	0.000
Y45.1 Salicylates	0.001	0.999	0.000
H90 Conductive and sensorineural hearing loss	0.001	0.999	0.000
J39 Other diseases of upper respiratory tract	0.000	0.999	0.001
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
H90-H95 Other disorders of ear	0.001	0.999	0.000
Chapter VIII Diseases of the ear and mastoid process	0.001	0.999	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.001	0.999	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.999	0.001
D03.3 Melanoma in situ of other and unspecified parts of face	0.001	0.999	0.000
H66.3 Other chronic suppurative otitis media	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
N48 Other disorders of penis	0.001	0.999	0.000
K86.9 Disease of pancreas, unspecified	0.001	0.999	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.999	0.000
H93 Other disorders of ear, not elsewhere classified	0.001	0.999	0.000
S92 Fracture of foot, except ankle	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.001	0.999	0.000
I44.2 Atrioventricular block, complete	0.000	0.999	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
G63.2 Diabetic polyneuropathy	0.000	0.999	0.001
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.999	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.999	0.000
H95.1 Other disorders following mastoidectomy	0.001	0.999	0.000
D22.0 Melanocytic naevi of lip	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
H35.6 Retinal haemorrhage	0.000	0.999	0.001
H66.4 Suppurative otitis media, unspecified	0.001	0.999	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.999	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.001	0.999	0.000
H66.0 Acute suppurative otitis media	0.001	0.999	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
H65-H75 Diseases of middle ear and mastoid	0.001	0.999	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.999	0.001
H34.1 Central retinal artery occlusion	0.000	0.999	0.001
H34.0 Transient retinal artery occlusion	0.000	0.999	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
H90.3 Sensorineural hearing loss, bilateral	0.001	0.999	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.999	0.001
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.999	0.001
J39.1 Other abscess of pharynx	0.000	0.999	0.001
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.999	0.001
R74.9 Abnormal level of unspecified serum enzyme	0.001	0.999	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
H93.9 Disorder of ear, unspecified	0.001	0.999	0.000
O26.8 Other specified pregnancy-related conditions	0.001	0.999	0.000
D22 Melanocytic naevi	0.001	0.999	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.001	0.999	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.999	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.999	0.001
D03 Melanoma in situ	0.001	0.999	0.000
H74 Other disorders of middle ear and mastoid	0.001	0.999	0.000
H70 Mastoiditis and related conditions	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
N48.5 Ulcer of penis	0.001	0.999	0.000
N48.3 Priapism	0.001	0.999	0.000
N48.0 Leukoplakia of penis	0.001	0.999	0.000
R49.0 Dysphonia	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
Q39 Congenital malformations of oesophagus	0.001	0.999	0.000
B00.4 Herpesviral encephalitis	0.001	0.999	0.000
H70.9 Mastoiditis, unspecified	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.001	0.999	0.000
H93.8 Other specified disorders of ear	0.001	0.999	0.000
H93.3 Disorders of acoustic nerve	0.001	0.999	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.999	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
N48.1 Balanoposthitis	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.999	0.001
A08.4 Viral intestinal infection, unspecified	0.000	0.999	0.001
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
F20.9 Schizophrenia, unspecified	0.000	0.999	0.001
H35 Other retinal disorders	0.000	0.999	0.001
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.999	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
H35.4 Peripheral retinal degeneration	0.000	0.999	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.999	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.999	0.001
N48.9 Disorder of penis, unspecified	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
Q38.1 Ankyloglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
D05 Carcinoma in situ of breast	0.000	0.999	0.001
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.001	0.999	0.000
G50.0 Trigeminal neuralgia	0.000	0.999	0.001
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.999	0.000
H74.1 Adhesive middle ear disease	0.001	0.999	0.000
H74.0 Tympanosclerosis	0.001	0.999	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.999	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
N41.1 Chronic prostatitis	0.000	0.999	0.001
Q87.4 Marfan's syndrome	0.001	0.999	0.000
H92 Otalgia and effusion of ear	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
B00.5 Herpesviral ocular disease	0.001	0.999	0.000
D03.9 Melanoma in situ, unspecified	0.001	0.999	0.000
D03.8 Melanoma in situ of other sites	0.001	0.999	0.000
D03.4 Melanoma in situ of scalp and neck	0.001	0.999	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.999	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.001	0.999	0.000
D03.0 Melanoma in situ of lip	0.001	0.999	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.001	0.999	0.000
H35.9 Retinal disorder, unspecified	0.000	0.999	0.001
I22.0 Subsequent myocardial infarction of anterior wall	0.001	0.999	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.999	0.000
Q39.8 Other congenital malformations of oesophagus	0.001	0.999	0.000
Q39.5 Congenital dilatation of oesophagus	0.001	0.999	0.000
Q39.4 Oesophageal web	0.001	0.999	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.001	0.999	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.001	0.999	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.001	0.999	0.000
Q39.0 Atresia of oesophagus without fistula	0.001	0.999	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.999	0.000
Z93.3 Colostomy status	0.000	0.999	0.001
Z95.0 Presence of cardiac pacemaker	0.001	0.999	0.000
B00 Herpesviral [herpes simplex] infections	0.001	0.999	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.999	0.001
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
H35.2 Other proliferative retinopathy	0.000	0.999	0.001
H35.1 Retinopathy of prematurity	0.000	0.999	0.001
H90.5 Sensorineural hearing loss, unspecified	0.001	0.999	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.999	0.000
Y83.4 Other reconstructive surgery	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
K91.3 Postoperative intestinal obstruction	0.001	0.999	0.000
O04.9 Complete or unspecified, without complication	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
Q43.7 Persistent cloaca	0.001	0.999	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.999	0.000
Q43.5 Ectopic anus	0.001	0.999	0.000
Q43.4 Duplication of intestine	0.001	0.999	0.000
Q43.3 Congenital malformations of intestinal fixation	0.001	0.999	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.999	0.001
D05.0 Lobular carcinoma in situ	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations