TreeWAS – Variant ID: rs12458596

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J81 Pulmonary oedema	0.000	0.028	0.972
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.043	0.957
J84 Other interstitial pulmonary diseases	0.000	0.053	0.947
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.073	0.927
J80 Adult respiratory distress syndrome	0.000	0.150	0.850
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.156	0.844
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.249	0.751
J84.8 Other specified interstitial pulmonary diseases	0.000	0.313	0.687
J84.0 Alveolar and parietoalveolar conditions	0.000	0.319	0.680
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.156	0.844	0.000
F31 Bipolar affective disorder	0.154	0.846	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.142	0.858	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.141	0.859	0.000
F31.9 Bipolar affective disorder, unspecified	0.135	0.865	0.000
F31.8 Other bipolar affective disorders	0.130	0.870	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.120	0.880	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.116	0.884	0.000
F31.7 Bipolar affective disorder, currently in remission	0.112	0.888	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.110	0.890	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.084	0.916	0.000
C32.0 Glottis	0.011	0.989	0.000
J31.0 Chronic rhinitis	0.000	0.990	0.010
Z98.1 Arthrodesis status	0.000	0.992	0.008
N42.9 Disorder of prostate, unspecified	0.000	0.992	0.008
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.008	0.992	0.000
C32 Malignant neoplasm of larynx	0.007	0.993	0.000
I44.2 Atrioventricular block, complete	0.000	0.993	0.007
F30-F39 Mood [affective] disorders	0.007	0.993	0.000
Y84.0 Cardiac catheterisation	0.000	0.993	0.007
C32.9 Larynx, unspecified	0.007	0.993	0.000
J31.2 Chronic pharyngitis	0.000	0.993	0.007
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.993	0.007
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.007	0.993	0.000
T91.3 Sequelae of injury of spinal cord	0.006	0.994	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.994	0.006
T91 Sequelae of injuries of neck and trunk	0.006	0.994	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.006	0.994	0.000
C32.8 Overlapping lesion of larynx	0.005	0.994	0.000
C32.3 Laryngeal cartilage	0.005	0.994	0.000
C32.2 Subglottis	0.005	0.994	0.000
F34 Persistent mood [affective] disorders	0.005	0.995	0.000
F38 Other mood [affective] disorders	0.005	0.995	0.000
M85.0 Fibrous dysplasia (monostotic)	0.005	0.995	0.000
C32.1 Supraglottis	0.005	0.995	0.000
T91.1 Sequelae of fracture of spine	0.005	0.995	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.005	0.995	0.000
M31.6 Other giant cell arteritis	0.000	0.995	0.005
S06.00 Concussion (without open intracranial wound)	0.000	0.995	0.005
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.005	0.995	0.000
F30 Manic episode	0.005	0.995	0.000
J31.1 Chronic nasopharyngitis	0.000	0.995	0.004
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.004	0.996	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.004	0.996	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.004	0.996	0.000
F39 Unspecified mood [affective] disorder	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.004	0.996	0.000
F34.1 Dysthymia	0.004	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.004	0.996	0.000
F34.8 Other persistent mood [affective] disorders	0.004	0.996	0.000
F34.0 Cyclothymia	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
F38.8 Other specified mood [affective] disorders	0.004	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.004	0.996	0.000
F38.0 Other single mood [affective] disorders	0.004	0.996	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.004	0.996	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.004	0.996	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.004	0.996	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.004	0.996	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.004	0.996	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.004	0.996	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.004	0.996	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.004	0.996	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.004	0.996	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
M85.6 Other cyst of bone	0.004	0.996	0.000
F30.0 Hypomania	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.000	0.996	0.004
C64 Malignant neoplasm of kidney, except renal pelvis	0.004	0.996	0.000
F30.2 Mania with psychotic symptoms	0.004	0.996	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.004	0.996	0.000
F30.8 Other manic episodes	0.003	0.996	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.996	0.000
F30.1 Mania without psychotic symptoms	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.003	0.997	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.003	0.997	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.003	0.997	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.003	0.997	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.003	0.997	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.003	0.997	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.003	0.997	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
Z36.9 Antenatal screening, unspecified	0.003	0.997	0.000
C65 Malignant neoplasm of renal pelvis	0.003	0.997	0.000
M85.69 Other cyst of bone (Site unspecified)	0.003	0.997	0.000
M85.66 Other cyst of bone (Lower leg)	0.003	0.997	0.000
M85.63 Other cyst of bone (Forearm)	0.003	0.997	0.000
M85.62 Other cyst of bone (Upper arm)	0.003	0.997	0.000
M85.61 Other cyst of bone (Shoulder region)	0.003	0.997	0.000
M85.60 Other cyst of bone (Multiple sites)	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.003	0.997	0.000
Z90.5 Acquired absence of kidney	0.003	0.997	0.000
S06.0 Concussion	0.000	0.997	0.003
S63.2 Multiple dislocations of fingers	0.003	0.997	0.000
G71.1 Myotonic disorders	0.000	0.997	0.003
M31 Other necrotising vasculopathies	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.003	0.997	0.000
M85.18 Skeletal fluorosis (Other)	0.003	0.997	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.003	0.997	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.003	0.997	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.003	0.997	0.000
M85.14 Skeletal fluorosis (Hand)	0.003	0.997	0.000
M85.13 Skeletal fluorosis (Forearm)	0.003	0.997	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.003	0.997	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.003	0.997	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.003	0.997	0.000
M85.39 Osteitis condensans (Site unspecified)	0.003	0.997	0.000
M85.38 Osteitis condensans (Other)	0.003	0.997	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.003	0.997	0.000
M85.36 Osteitis condensans (Lower leg)	0.003	0.997	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.003	0.997	0.000
M85.34 Osteitis condensans (Hand)	0.003	0.997	0.000
M85.33 Osteitis condensans (Forearm)	0.003	0.997	0.000
M85.32 Osteitis condensans (Upper arm)	0.003	0.997	0.000
M85.31 Osteitis condensans (Shoulder region)	0.003	0.997	0.000
M85.30 Osteitis condensans (Multiple sites)	0.003	0.997	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.003	0.997	0.000
M85.48 Solitary bone cyst (Other)	0.003	0.997	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.44 Solitary bone cyst (Hand)	0.003	0.997	0.000
M85.43 Solitary bone cyst (Forearm)	0.003	0.997	0.000
M85.42 Solitary bone cyst (Upper arm)	0.003	0.997	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.003	0.997	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.003	0.997	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.003	0.997	0.000
M85.58 Aneurysmal bone cyst (Other)	0.003	0.997	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.003	0.997	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.003	0.997	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.003	0.997	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.003	0.997	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.003	0.997	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.003	0.997	0.000
C30.0 Nasal cavity	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.997	0.000
C25.2 Tail of pancreas	0.000	0.997	0.003
M31.1 Thrombotic microangiopathy	0.000	0.997	0.003
M31.0 Hypersensitivity angiitis	0.000	0.997	0.003
S63.5 Sprain and strain of wrist	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.997	0.003
M85.29 Hyperostosis of skull-Site unspec	0.002	0.997	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.997	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.997	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.997	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.997	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.997	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.997	0.000
M85.22 Hyperostosis of skull-Upper arm	0.002	0.997	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.997	0.000
M85.68 Other cyst of bone (Other)	0.002	0.997	0.000
J32.8 Other chronic sinusitis	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
C30 Malignant neoplasm of nasal cavity and middle ear	0.002	0.998	0.000
C25.3 Pancreatic duct	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
N34.2 Other urethritis	0.002	0.998	0.000
N48.0 Leukoplakia of penis	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.998	0.000
J86.0 Pyothorax with fistula	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.000	0.998	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
C25.0 Head of pancreas	0.000	0.998	0.002
G71 Primary disorders of muscles	0.000	0.998	0.002
C77.0 Lymph nodes of head, face and neck	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.000	0.998	0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.002	0.998	0.000
M31.7 Microscopic polyangiitis	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.002	0.998	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
C30.1 Middle ear	0.002	0.998	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
N30.0 Acute cystitis	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.002
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.002
G71.8 Other primary disorders of muscles	0.000	0.998	0.002
G71.2 Congenital myopathies	0.000	0.998	0.002
C33 Malignant neoplasm of trachea	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
C25.1 Body of pancreas	0.000	0.998	0.002
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.002	0.998	0.000
C31 Malignant neoplasm of accessory sinuses	0.002	0.998	0.000
B02.9 Zoster without complication	0.000	0.998	0.002
K51.2 Ulcerative (chronic) proctitis	0.000	0.998	0.002
O30.0 Twin pregnancy	0.002	0.998	0.000
C37 Malignant neoplasm of thymus	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
S50.8 Other superficial injuries of forearm	0.002	0.998	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.002
J32.4 Chronic pansinusitis	0.000	0.998	0.002
C38.3 Mediastinum, part unspecified	0.002	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
C31.9 Accessory sinus, unspecified	0.001	0.998	0.000
C31.8 Overlapping lesion of accessory sinuses	0.001	0.998	0.000
C31.3 Sphenoidal sinus	0.001	0.998	0.000
C31.2 Frontal sinus	0.001	0.998	0.000
C31.1 Ethmoidal sinus	0.001	0.998	0.000
C31.0 Maxillary sinus	0.001	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.001	0.998	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.001	0.998	0.000
C39.0 Upper respiratory tract, part unspecified	0.001	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
N42.2 Atrophy of prostate	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
H54.4 Blindness, one eye	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.001	0.998	0.000
C38.2 Posterior mediastinum	0.001	0.998	0.000
C38.1 Anterior mediastinum	0.001	0.998	0.000
C38.0 Heart	0.001	0.998	0.000
B59 Pneumocystosis	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.998	0.001
M82.1 Osteoporosis in endocrine disorders	0.001	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
G82.1 Spastic paraplegia	0.001	0.998	0.000
M31.3 Wegener's granulomatosis	0.000	0.998	0.001
N42 Other disorders of prostate	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.001	0.999	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.999	0.001
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.001	0.999	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.999	0.001
G82.2 Paraplegia, unspecified	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.000	0.999	0.001
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
O14.1 Severe preeclampsia	0.001	0.999	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.999	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.999	0.001
F33.9 Recurrent depressive disorder, unspecified	0.001	0.999	0.000
N81.6 Rectocele	0.001	0.999	0.000
N88.2 Stricture and stenosis of cervix uteri	0.001	0.999	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.999	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.999	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.999	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.999	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.999	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.999	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.999	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
C68.9 Urinary organ, unspecified	0.001	0.999	0.000
F32.1 Moderate depressive episode	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
J86 Pyothorax	0.001	0.999	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
C38.4 Pleura	0.001	0.999	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.999	0.000
C68.1 Paraurethral glands	0.001	0.999	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.001	0.999	0.000
S06.2 Diffuse brain injury	0.000	0.999	0.001
J15.4 Pneumonia due to other streptococci	0.001	0.999	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.999	0.001
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
M83.80 Other adult osteomalacia (Multiple sites)	0.001	0.999	0.000
J15.8 Other bacterial pneumonia	0.001	0.999	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.001	0.999	0.000
M82 Osteoporosis in diseases classified elsewhere	0.001	0.999	0.000
C71.9 Brain, unspecified	0.000	0.999	0.001
O62.2 Other uterine inertia	0.001	0.999	0.000
S70.1 Contusion of thigh	0.000	0.999	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.999	0.001
F33.0 Recurrent depressive disorder, current episode mild	0.001	0.999	0.000
J17.3 Pneumonia in parasitic diseases	0.001	0.999	0.000
K65.0 Acute peritonitis	0.001	0.999	0.000
N42.3 Dysplasia of prostate	0.000	0.999	0.001
C66 Malignant neoplasm of ureter	0.001	0.999	0.001
J15.9 Bacterial pneumonia, unspecified	0.001	0.999	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.001	0.999	0.000
O14.2 HELLP syndrome	0.001	0.999	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.999	0.001
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.999	0.001
G82 Paraplegia and tetraplegia	0.001	0.999	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.999	0.001
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.001	0.999	0.000
J15.3 Pneumonia due to streptococcus, group B	0.001	0.999	0.000
M83.8 Other adult osteomalacia	0.001	0.999	0.000
W24.9 Unspecified place	0.001	0.999	0.000
C71 Malignant neoplasm of brain	0.000	0.999	0.001
D32.0 Cerebral meninges	0.000	0.999	0.001
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.999	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.999	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.999	0.000
S06 Intracranial injury	0.000	0.999	0.001
C68.0 Urethra	0.001	0.999	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.999	0.000
H47.2 Optic atrophy	0.001	0.999	0.000
M35.3 Polymyalgia rheumatica	0.000	0.999	0.001
X23.9 Unspecified place	0.001	0.999	0.000
H54 Blindness and low vision	0.001	0.999	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.999	0.001
D37.4 Colon	0.000	0.999	0.001
E11.0 With coma	0.000	0.999	0.001
F60.5 Anankastic personality disorder	0.001	0.999	0.000
G82.3 Flaccid tetraplegia	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.001	0.999	0.000
L11.0 Acquired keratosis follicularis	0.001	0.999	0.000
N34.1 Nonspecific urethritis	0.001	0.999	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
C67.0 Trigone of bladder	0.000	0.999	0.001
C71.8 Overlapping lesion of brain	0.000	0.999	0.001
C71.5 Cerebral ventricle	0.000	0.999	0.001
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.999	0.001
S06.9 Intracranial injury, unspecified	0.000	0.999	0.001
W55.0 Home	0.001	0.999	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.999	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.999	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.999	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.999	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.999	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.999	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.999	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.999	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.999	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.999	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.999	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.88 Other adult osteomalacia (Other)	0.001	0.999	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.001	0.999	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.84 Other adult osteomalacia (Hand)	0.001	0.999	0.000
M83.83 Other adult osteomalacia (Forearm)	0.001	0.999	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.001	0.999	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.001	0.999	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.999	0.001
G82.4 Spastic tetraplegia	0.001	0.999	0.000
K35.8 Acute appendicitis, other and unspecified	0.001	0.999	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.999	0.001
T31.0 Burns involving less than 10% of body surface	0.000	0.999	0.001
M83 Adult osteomalacia	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.999	0.001
D22.9 Melanocytic naevi, unspecified	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.999	0.001
N34.0 Urethral abscess	0.001	0.999	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.001	0.999	0.000
Z43.2 Attention to ileostomy	0.001	0.999	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.999	0.001
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.999	0.001
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.999	0.001
B35.3 Tinea pedis	0.000	0.999	0.001
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.999	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.001	0.999	0.000
N34 Urethritis and urethral syndrome	0.001	0.999	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.999	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.001	0.999	0.000
F64.0 Transsexualism	0.001	0.999	0.000
G72.0 Drug-induced myopathy	0.000	0.999	0.001
I37.1 Pulmonary valve insufficiency	0.001	0.999	0.000
J33.8 Other polyp of sinus	0.000	0.999	0.001
M83.9 Adult osteomalacia, unspecified	0.001	0.999	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.999	0.000
M83.4 Aluminum bone disease	0.001	0.999	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.999	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.999	0.000
M83.0 Puerperal osteomalacia	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.999	0.001
N88.1 Old laceration of cervix uteri	0.001	0.999	0.000
O20 Haemorrhage in early pregnancy	0.000	0.999	0.001
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.999	0.001
C71.4 Occipital lobe	0.000	0.999	0.001
F60.0 Paranoid personality disorder	0.001	0.999	0.000
G82.5 Tetraplegia, unspecified	0.001	0.999	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.999	0.001
J35.1 Hypertrophy of tonsils	0.001	0.999	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.999	0.001
L73.2 Hidradenitis suppurativa	0.000	0.999	0.001
M83.1 Senile osteomalacia	0.001	0.999	0.000
S06.1 Traumatic cerebral oedema	0.000	0.999	0.001
B07 Viral warts	0.000	0.999	0.001
M46.49 Discitis, unspecified (Site unspecified)	0.000	0.999	0.001
M54.50 Low back pain (Multiple sites in spine)	0.001	0.999	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.08 Puerperal osteomalacia (Other)	0.001	0.999	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.001	0.999	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.04 Puerperal osteomalacia (Hand)	0.001	0.999	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.001	0.999	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.001	0.999	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.001	0.999	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.001	0.999	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.001	0.999	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.001	0.999	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.001	0.999	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.001	0.999	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.001	0.999	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.001	0.999	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.001	0.999	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.001	0.999	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.001	0.999	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.001	0.999	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.001	0.999	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.001	0.999	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.001	0.999	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.001	0.999	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.001	0.999	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.001	0.999	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.001	0.999	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.001	0.999	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.001	0.999	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.001	0.999	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.001	0.999	0.000
M83.48 Aluminium bone disease (Other)	0.001	0.999	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.001	0.999	0.000
M83.46 Aluminium bone disease (Lower leg)	0.001	0.999	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.001	0.999	0.000
M83.44 Aluminium bone disease (Hand)	0.001	0.999	0.000
M83.43 Aluminium bone disease (Forearm)	0.001	0.999	0.000
M83.42 Aluminium bone disease (Upper arm)	0.001	0.999	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.001	0.999	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.001	0.999	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.001	0.999	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.001	0.999	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.001	0.999	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.001	0.999	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations