TreeWAS – Variant ID: rs12477249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.736	0.264	0.000
E78.5 Hyperlipidaemia, unspecified	0.723	0.277	0.000
E78.2 Mixed hyperlipidaemia	0.606	0.394	0.000
E78.3 Hyperchylomicronaemia	0.541	0.459	0.000
E78.6 Lipoprotein deficiency	0.497	0.503	0.000
E78.8 Other disorders of lipoprotein metabolism	0.471	0.529	0.000
E78.4 Other hyperlipidaemia	0.428	0.572	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.400	0.600	0.000
E78.1 Pure hyperglyceridaemia	0.340	0.659	0.000
K13.0 Diseases of lips	0.014	0.986	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.010	0.990	0.000
S42.00 Fracture of clavicle (closed)	0.009	0.991	0.000
E70-E90 Metabolic disorders	0.008	0.992	0.000
E88 Other metabolic disorders	0.007	0.993	0.000
E88.8 Other specified metabolic disorders	0.007	0.993	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.006	0.994	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.994	0.006
E73 Lactose intolerance	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
U80.0 Penicillin resistant agent	0.006	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.006	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.006	0.994	0.000
E70 Disorders of aromatic amino-acid metabolism	0.006	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.006	0.994	0.000
S80.9 Superficial injury of lower leg, unspecified	0.006	0.994	0.000
S80 Superficial injury of lower leg	0.006	0.994	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.006	0.994	0.000
S80.8 Other superficial injuries of lower leg	0.006	0.994	0.000
E88.9 Metabolic disorder, unspecified	0.005	0.994	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.006	0.994	0.000
E84 Cystic fibrosis	0.005	0.994	0.000
E79 Disorders of purine and pyrimidine metabolism	0.005	0.994	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.005	0.994	0.000
S80.0 Contusion of knee	0.005	0.995	0.000
E88.3 Tumour lysis syndrome	0.005	0.995	0.000
S42.0 Fracture of clavicle	0.005	0.995	0.000
E74 Other disorders of carbohydrate metabolism	0.005	0.995	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.005	0.995	0.000
E73.9 Lactose intolerance, unspecified	0.005	0.995	0.000
E85 Amyloidosis	0.005	0.995	0.000
U80 Agent resistant to penicillin and related antibiotics	0.005	0.995	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.005	0.995	0.000
E73.8 Other lactose intolerance	0.005	0.995	0.000
E73.1 Secondary lactase deficiency	0.005	0.995	0.000
E73.0 Congenital lactase deficiency	0.005	0.995	0.000
I44.7 Left bundle-branch block, unspecified	0.005	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.995	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.995	0.000
E70.3 Albinism	0.004	0.995	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.995	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.995	0.000
E70.0 Classical phenylketonuria	0.004	0.995	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.995	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.995	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.995	0.000
E71.0 Maple-syrup-urine disease	0.004	0.995	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.995	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.995	0.000
E72.5 Disorders of glycine metabolism	0.004	0.995	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.995	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.995	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.995	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.995	0.000
E72.0 Disorders of amino-acid transport	0.004	0.995	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.995	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.995	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.995	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.995	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.995	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.995	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.995	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.995	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.995	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.004	0.995	0.000
S80.7 Multiple superficial injuries of lower leg	0.004	0.995	0.000
E80.6 Other disorders of bilirubin metabolism	0.004	0.996	0.000
Z88.2 Personal history of allergy to sulphonamides	0.004	0.996	0.000
E80.2 Other porphyria	0.004	0.996	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.996	0.004
E75.6 Lipid storage disorder, unspecified	0.004	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.996	0.000
E75.2 Other sphingolipidosis	0.004	0.996	0.000
E75.1 Other gangliosidosis	0.004	0.996	0.000
E75.0 GM2 gangliosidosis	0.004	0.996	0.000
Z34 Supervision of normal pregnancy	0.000	0.996	0.004
E80.5 Crigler-Najjar syndrome	0.004	0.996	0.000
E80.3 Defects of catalase and peroxydase	0.004	0.996	0.000
E80.0 Hereditary erythropoietic porphyria	0.004	0.996	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.004	0.996	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.996	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.996	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.996	0.000
E80.1 Porphyria cutanea tarda	0.004	0.996	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
E85.8 Other amyloidosis	0.004	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.004	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.004	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.004	0.996	0.000
E74.2 Disorders of galactose metabolism	0.004	0.996	0.000
E74.1 Disorders of fructose metabolism	0.004	0.996	0.000
E74.0 Glycogen storage disease	0.004	0.996	0.000
S42.01 Fracture of clavicle (open)	0.004	0.996	0.000
E83.3 Disorders of phosphorus metabolism	0.004	0.996	0.000
E75.5 Other lipid storage disorders	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.996	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.004	0.996	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.004	0.996	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.996	0.004
N04.9 Unspecified	0.004	0.996	0.000
S40 Superficial injury of shoulder and upper arm	0.004	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.996	0.000
H71 Cholesteatoma of middle ear	0.000	0.996	0.004
E74.3 Other disorders of intestinal carbohydrate absorption	0.003	0.997	0.000
I49.0 Ventricular fibrillation and flutter	0.003	0.997	0.000
I70 Atherosclerosis	0.003	0.997	0.000
E83 Disorders of mineral metabolism	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
K76.9 Liver disease, unspecified	0.000	0.997	0.003
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.003	0.997	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.997	0.003
I70.1 Atherosclerosis of renal artery	0.003	0.997	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
C84.0 Mycosis fungoides	0.003	0.997	0.000
B44.9 Aspergillosis, unspecified	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
I70.8 Atherosclerosis of other arteries	0.003	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.003	0.997	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.997	0.003
G12.2 Motor neuron disease	0.000	0.997	0.003
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.997	0.003
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.003	0.997	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.997	0.003
C84.8 Cutaneous T-cell lymphoma, unspecified	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.003	0.997	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.003	0.997	0.000
E83.8 Other disorders of mineral metabolism	0.003	0.997	0.000
E83.2 Disorders of zinc metabolism	0.003	0.997	0.000
E83.0 Disorders of copper metabolism	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.997	0.003
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.997	0.000
R74.8 Abnormal levels of other serum enzymes	0.003	0.997	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.000	0.997	0.003
B44.1 Other pulmonary aspergillosis	0.000	0.997	0.003
E87.5 Hyperkalaemia	0.003	0.997	0.000
U51 Admission status on psychiatric patients	0.003	0.997	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.997	0.003
O42.9 Premature rupture of membranes, unspecified	0.000	0.997	0.003
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.997	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.002
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
J14 Pneumonia due to Haemophilus influenzae	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.002	0.998	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.002	0.998	0.000
Z32.1 Pregnancy confirmed	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.002	0.998	0.000
Z89 Acquired absence of limb	0.000	0.998	0.002
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
C84.9 Mature T/NK-cell lymphoma, unspecified	0.002	0.998	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.002	0.998	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.002	0.998	0.000
C84.3 Lymphoepithelioid lymphoma	0.002	0.998	0.000
C84.2 T-zone lymphoma	0.002	0.998	0.000
C84.1 Sezary's diease	0.002	0.998	0.000
B44 Aspergillosis	0.000	0.998	0.002
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
K76 Other diseases of liver	0.000	0.998	0.002
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.002	0.998	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.998	0.002
E87 Other disorders of fluid, electrolyte and acid-base balance	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.001	0.998	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.002	0.998	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.002
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.002	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
N23 Unspecified renal colic	0.000	0.998	0.002
B44.8 Other forms of aspergillosis	0.000	0.998	0.002
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
E87.6 Hypokalaemia	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.002	0.998	0.000
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.998	0.002
K76.4 Peliosis hepatis	0.000	0.998	0.002
K76.3 Infarction of liver	0.000	0.998	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.998	0.002
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.002	0.998	0.000
U06.9 Emergency use of U06.9	0.002	0.998	0.000
U06.8 Emergency use of U06.8	0.002	0.998	0.000
U06.7 Emergency use of U06.7	0.002	0.998	0.000
U06.6 Emergency use of U06.6	0.002	0.998	0.000
U06.5 Emergency use of U06.5	0.002	0.998	0.000
U06.4 Emergency use of U06.4	0.002	0.998	0.000
U06.3 Emergency use of U06.3	0.002	0.998	0.000
U06.2 Emergency use of U06.2	0.002	0.998	0.000
U06.1 Emergency use of U06.1	0.002	0.998	0.000
U06.0 Emergency use of U06.0	0.002	0.998	0.000
U07.9 Emergency use of U07.9	0.002	0.998	0.000
U07.8 Emergency use of U07.8	0.002	0.998	0.000
U07.7 Emergency use of U07.7	0.002	0.998	0.000
U07.6 Emergency use of U07.6	0.002	0.998	0.000
U07.5 Emergency use of U07.5	0.002	0.998	0.000
U07.4 Emergency use of U07.4	0.002	0.998	0.000
U07.3 Emergency use of U07.3	0.002	0.998	0.000
U07.2 Emergency use of U07.2	0.002	0.998	0.000
U07.1 Emergency use of U07.1	0.002	0.998	0.000
U07.0 Emergency use of U07.0	0.002	0.998	0.000
U50.9 Inquest Adjourned Death	0.002	0.998	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.002	0.998	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.002	0.998	0.000
U50.1 Level of care administered to neonates (Special Care)	0.002	0.998	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.000	0.998	0.002
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.002	0.998	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.000	0.998	0.001
O90 Complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
S42.1 Fracture of scapula	0.002	0.998	0.000
N04 Nephrotic syndrome	0.002	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.002	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S44 Injury of nerves at shoulder and upper arm level	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.998	0.002
E87.4 Mixed disorder of acid-base balance	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.000	0.998	0.002
T21.7 Corrosion of third degree of trunk	0.002	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.002	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.002	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.002	0.998	0.000
T21.1 Burn of first degree of trunk	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.998	0.001
K61.0 Anal abscess	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.000	0.998	0.002
I63 Cerebral infarction	0.002	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.002	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.002	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.002	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.002	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.002	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.002	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
K82.9 Disease of gallbladder, unspecified	0.000	0.998	0.002
S00.8 Superficial injury of other parts of head	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
G12 Spinal muscular atrophy and related syndromes	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.000	0.998	0.001
O90.4 Postpartum acute renal failure	0.000	0.998	0.001
O90.3 Cardiomyopathy in the puerperium	0.000	0.998	0.001
Q87.4 Marfan's syndrome	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.001	0.998	0.000
J05.1 Acute epiglottitis	0.002	0.998	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.002
M70.2 Olecranon bursitis	0.000	0.998	0.001
N04.8 Other	0.001	0.998	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.998	0.000
N04.6 Dense deposit disease	0.001	0.998	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.998	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
N04.0 Minor glomerular abnormality	0.001	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.002	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.001	0.998	0.000
K13.3 Hairy leukoplakia	0.001	0.998	0.000
K13.1 Cheek and lip biting	0.001	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.001	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.998	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.001	0.998	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.001	0.998	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.001	0.998	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.001	0.998	0.000
S44.4 Injury of musculocutaneous nerve	0.001	0.998	0.000
S44.3 Injury of axillary nerve	0.001	0.998	0.000
S44.2 Injury of radial nerve at upper arm level	0.001	0.998	0.000
S44.1 Injury of median nerve at upper arm level	0.001	0.998	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.001	0.998	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.001	0.998	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.001	0.998	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.001	0.998	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.001	0.998	0.000
S45.2 Injury of axillary or brachial vein	0.001	0.998	0.000
S45.1 Injury of brachial artery	0.001	0.998	0.000
S45.0 Injury of axillary artery	0.001	0.998	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.001	0.998	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.001	0.998	0.000
S48.0 Traumatic amputation at shoulder joint	0.001	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.001	0.998	0.000
J46 Status asthmaticus	0.000	0.998	0.002
S42.31 Fracture of shaft of humerus (open)	0.001	0.998	0.000
E83.4 Disorders of magnesium metabolism	0.001	0.998	0.000
K13.5 Oral submucous fibrosis	0.001	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.001	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.001	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.001	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.001
M30.0 Polyarteritis nodosa	0.001	0.998	0.000
N04.2 Diffuse membranous glomerulonephritis	0.001	0.998	0.000
N04.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.000	0.998	0.001
F22 Persistent delusional disorders	0.001	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
H35.0 Background retinopathy and retinal vascular changes	0.000	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.001	0.999	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.999	0.000
S30.1 Contusion of abdominal wall	0.001	0.999	0.000
Z63.5 Disruption of family by separation and divorce	0.001	0.999	0.000
G12.9 Spinal muscular atrophy, unspecified	0.000	0.999	0.001
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.999	0.001
G12.1 Other inherited spinal muscular atrophy	0.000	0.999	0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.999	0.001
S41.7 Multiple open wounds of shoulder and upper arm	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
C43.6 Malignant melanoma of upper limb, including shoulder	0.001	0.999	0.000
K82.2 Perforation of gallbladder	0.000	0.999	0.001
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.999	0.000
S41.0 Open wound of shoulder	0.001	0.999	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.999	0.000
I63.8 Other cerebral infarction	0.001	0.999	0.000
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
W26.8 Other specified place	0.001	0.999	0.000
S42.21 Fracture of upper end of humerus (open)	0.001	0.999	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.999	0.001
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
M70.29 Olecranon bursitis-Site unspec	0.000	0.999	0.001
M70.28 Olecranon bursitis-Other	0.000	0.999	0.001
M70.27 Olecranon bursitis-Ankle/Foot	0.000	0.999	0.001
M70.26 Olecranon bursitis-Lower Leg	0.000	0.999	0.001
M70.25 Olecranon bursitis-Pelvic/Thigh	0.000	0.999	0.001
M70.24 Olecranon bursitis-Hand	0.000	0.999	0.001
M70.23 Olecranon bursitis-Forearm	0.000	0.999	0.001
M70.21 Olecranon bursitis-Shldr region	0.000	0.999	0.001
M70.20 Olecranon bursitis-Mult sites	0.000	0.999	0.001
F22.9 Persistent delusional disorder, unspecified	0.001	0.999	0.000
M41.9 Scoliosis, unspecified	0.000	0.999	0.001
Z11.2 Special screening examination for other bacterial diseases	0.000	0.999	0.001
F23 Acute and transient psychotic disorders	0.001	0.999	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.001	0.999	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.001	0.999	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.001	0.999	0.000
E89.5 Postprocedural testicular hypofunction	0.001	0.999	0.000
E89.1 Postprocedural hypoinsulinaemia	0.001	0.999	0.000
O63.9 Long labour, unspecified	0.001	0.999	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.999	0.001
F22.8 Other persistent delusional disorders	0.001	0.999	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.999	0.001
D22.7 Melanocytic naevi of lower limb, including hip	0.001	0.999	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.999	0.001
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.999	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.001	0.999	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.001	0.999	0.000
M79.62 Pain in limb (Upper arm)	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
E89.4 Postprocedural ovarian failure	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
K65.9 Peritonitis, unspecified	0.000	0.999	0.001
R41.1 Anterograde amnesia	0.001	0.999	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.999	0.001
S89.9 Unspecified injury of lower leg	0.001	0.999	0.000
Z63.8 Other specified problems related to primary support group	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.999	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
F23.8 Other acute and transient psychotic disorders	0.001	0.999	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.999	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.999	0.000
G93.0 Cerebral cysts	0.000	0.999	0.001
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.999	0.001
S86.0 Injury of Achilles tendon	0.001	0.999	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.000	0.999	0.001
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.999	0.000
D43.2 Brain, unspecified	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.000	0.999	0.001
E83.1 Disorders of iron metabolism	0.000	0.999	0.001
G93.8 Other specified disorders of brain	0.000	0.999	0.001
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
D28.0 Vulva	0.000	0.999	0.001
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.999	0.001
Z99.8 Dependence on other enabling machines and devices	0.000	0.999	0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001
I28.8 Other specified diseases of pulmonary vessels	0.001	0.999	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.001	0.999	0.000
O41.0 Oligohydramnios	0.001	0.999	0.000
M53.8 Other specified dorsopathies	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.999	0.000
W20.8 Other specified place	0.001	0.999	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.999	0.001
Z12.8 Special screening examination for neoplasm of other sites	0.001	0.999	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S32.10 Fracture of sacrum (closed)	0.001	0.999	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.999	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.001	0.999	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations