TreeWAS – Variant ID: rs12489120

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.1 Aortic (valve) insufficiency	0.000	0.970	0.030
I49.9 Cardiac arrhythmia, unspecified	0.000	0.974	0.026
I49 Other cardiac arrhythmias	0.000	0.975	0.025
I35 Nonrheumatic aortic valve disorders	0.000	0.977	0.023
I51.9 Heart disease, unspecified	0.000	0.978	0.022
I49.5 Sick sinus syndrome	0.000	0.978	0.022
I49.8 Other specified cardiac arrhythmias	0.000	0.978	0.022
I51 Complications and ill-defined descriptions of heart disease	0.000	0.979	0.021
I51.7 Cardiomegaly	0.000	0.979	0.021
I49.1 Atrial premature depolarisation	0.000	0.979	0.021
I35.9 Aortic valve disorder, unspecified	0.000	0.980	0.020
I38 Endocarditis, valve unspecified	0.000	0.981	0.019
I30-I52 Other forms of heart disease	0.000	0.981	0.019
I49.4 Other and unspecified premature depolarisation	0.000	0.981	0.019
I51.4 Myocarditis, unspecified	0.000	0.982	0.018
I49.2 Junctional premature depolarisation	0.000	0.982	0.018
I49.3 Ventricular premature depolarisation	0.000	0.982	0.017
I35.8 Other aortic valve disorders	0.000	0.983	0.017
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.984	0.016
I51.6 Cardiovascular disease, unspecified	0.000	0.984	0.016
I51.5 Myocardial degeneration	0.000	0.984	0.016
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.984	0.016
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.984	0.016
I49.0 Ventricular fibrillation and flutter	0.000	0.986	0.014
I34 Nonrheumatic mitral valve disorders	0.000	0.986	0.014
I36 Nonrheumatic tricuspid valve disorders	0.000	0.986	0.014
I52 Other heart disorders in diseases classified elsewhere	0.000	0.986	0.014
I48 Atrial fibrillation and flutter	0.000	0.986	0.014
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.986	0.014
I41 Myocarditis in diseases classified elsewhere	0.000	0.986	0.014
I40 Acute myocarditis	0.000	0.986	0.014
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.986	0.014
I32 Pericarditis in diseases classified elsewhere	0.000	0.986	0.014
I33 Acute and subacute endocarditis	0.000	0.986	0.014
I34.1 Mitral (valve) prolapse	0.000	0.986	0.014
I37 Pulmonary valve disorders	0.000	0.986	0.013
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.987	0.013
I51.0 Cardiac septal defect, acquired	0.000	0.988	0.012
I46 Cardiac arrest	0.000	0.988	0.012
I44 Atrioventricular and left bundle-branch block	0.000	0.988	0.012
I30 Acute pericarditis	0.000	0.988	0.012
I47 Paroxysmal tachycardia	0.000	0.989	0.011
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.989	0.010
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.989	0.010
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.989	0.010
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.989	0.010
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.989	0.010
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.989	0.010
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.990	0.010
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.990	0.010
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.990	0.010
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.990	0.010
I40.9 Acute myocarditis, unspecified	0.000	0.990	0.010
I40.8 Other acute myocarditis	0.000	0.990	0.010
I40.1 Isolated myocarditis	0.000	0.990	0.010
I40.0 Infective myocarditis	0.000	0.990	0.010
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.990	0.010
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.990	0.010
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.990	0.010
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.990	0.010
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.990	0.010
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.990	0.010
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.990	0.010
I48.4 Atypical atrial flutter	0.000	0.990	0.010
I48.3 Typical atrial flutter	0.000	0.990	0.010
I48.2 Chronic atrial fibrillation	0.000	0.990	0.010
I48.1 Persistent atrial fibrillation	0.000	0.990	0.010
I48.0 Paroxysmal atrial fibrillation	0.000	0.990	0.010
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.990	0.010
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.990	0.010
I44.3 Other and unspecified atrioventricular block	0.000	0.990	0.010
I44.0 Atrioventricular block, first degree	0.000	0.990	0.010
I33.9 Acute endocarditis, unspecified	0.000	0.990	0.010
I33.0 Acute and subacute infective endocarditis	0.000	0.990	0.010
I46.9 Cardiac arrest, unspecified	0.000	0.990	0.010
I37.9 Pulmonary valve disorder, unspecified	0.000	0.990	0.010
I37.8 Other pulmonary valve disorders	0.000	0.990	0.010
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.990	0.010
I37.0 Pulmonary valve stenosis	0.000	0.990	0.010
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.990	0.010
I37.1 Pulmonary valve insufficiency	0.000	0.991	0.009
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.991	0.009
I46.1 Sudden cardiac death, so described	0.000	0.991	0.009
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.991	0.009
I30.1 Infective pericarditis	0.000	0.991	0.009
I44.2 Atrioventricular block, complete	0.000	0.991	0.009
I44.5 Left posterior fascicular block	0.000	0.991	0.009
I44.4 Left anterior fascicular block	0.000	0.991	0.009
I30.8 Other forms of acute pericarditis	0.000	0.991	0.009
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.991	0.009
I47.1 Supraventricular tachycardia	0.000	0.991	0.009
I44.6 Other and unspecified fascicular block	0.000	0.992	0.008
I47.0 Reentry ventricular arrhythmia	0.000	0.992	0.008
M06.9 Rheumatoid arthritis, unspecified	0.000	0.992	0.008
I31 Other diseases of pericardium	0.000	0.992	0.007
J92.0 Pleural plaque with presence of asbestos	0.007	0.993	0.000
J92.9 Pleural plaque without asbestos	0.007	0.993	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.993	0.007
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.993	0.007
J92 Pleural plaque	0.007	0.993	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.994	0.006
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.994	0.006
I30.9 Acute pericarditis, unspecified	0.000	0.994	0.006
K08.3 Retained dental root	0.000	0.994	0.006
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.994	0.006
I44.1 Atrioventricular block, second degree	0.000	0.994	0.006
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.006	0.994	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.994	0.006
I47.2 Ventricular tachycardia	0.000	0.994	0.006
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.994	0.006
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.994	0.006
I31.8 Other specified diseases of pericardium	0.000	0.994	0.005
I31.2 Haemopericardium, not elsewhere classified	0.000	0.994	0.005
I31.1 Chronic constrictive pericarditis	0.000	0.994	0.005
I31.0 Chronic adhesive pericarditis	0.000	0.994	0.005
Z88.2 Personal history of allergy to sulphonamides	0.000	0.995	0.005
C91.1 Chronic lymphocytic leukaemia	0.005	0.995	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.005	0.995	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.995	0.005
I34.0 Mitral (valve) insufficiency	0.000	0.995	0.005
I51.8 Other ill-defined heart diseases	0.000	0.995	0.005
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.995	0.005
F10.1 Harmful use	0.005	0.995	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.005	0.995	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.995	0.004
I35.0 Aortic (valve) stenosis	0.000	0.995	0.004
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.995	0.005
C43.4 Malignant melanoma of scalp and neck	0.004	0.996	0.000
F31.9 Bipolar affective disorder, unspecified	0.004	0.996	0.000
C43.9 Malignant melanoma of skin, unspecified	0.004	0.996	0.000
I42 Cardiomyopathy	0.002	0.996	0.002
C43 Malignant melanoma of skin	0.004	0.996	0.000
N80.8 Other endometriosis	0.004	0.996	0.000
D37.4 Colon	0.004	0.996	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
E53.8 Deficiency of other specified B group vitamins	0.000	0.996	0.004
C91 Lymphoid leukaemia	0.004	0.996	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.004	0.996	0.000
M06 Other rheumatoid arthritis	0.000	0.996	0.004
C43.2 Malignant melanoma of ear and external auricular canal	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
T81.8 Other complications of procedures, not elsewhere classified	0.003	0.997	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.997	0.002
I42.5 Other restrictive cardiomyopathy	0.002	0.997	0.002
I42.4 Endocardial fibroelastosis	0.002	0.997	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.997	0.002
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
C43.8 Overlapping malignant melanoma of skin	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.003	0.997	0.000
C43.0 Malignant melanoma of lip	0.003	0.997	0.000
J91 Pleural effusion in conditions classified elsewhere	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.997	0.002
O16 Unspecified maternal hypertension	0.000	0.997	0.003
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.002	0.997	0.002
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.997	0.003
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
C91.4 Hairy-cell leukaemia	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.997	0.001
I42.2 Other hypertrophic cardiomyopathy	0.002	0.997	0.001
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
I45 Other conduction disorders	0.000	0.997	0.003
C43.5 Malignant melanoma of trunk	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
F31 Bipolar affective disorder	0.003	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
L40.5 Arthropathic psoriasis	0.000	0.997	0.003
J90-J94 Other diseases of pleura	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.997	0.003
C91.8 Mature B-cell leukaemia Burkitt-type	0.003	0.997	0.000
C91.7 Other lymphoid leukaemia	0.003	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.003	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.003	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
L81.9 Disorder of pigmentation, unspecified	0.003	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.003
M06.2 Rheumatoid bursitis	0.000	0.997	0.003
M06.1 Adult-onset Still's disease	0.000	0.997	0.003
I45.2 Bifascicular block	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
M06.3 Rheumatoid nodule	0.000	0.997	0.003
M06.0 Seronegative rheumatoid arthritis	0.000	0.997	0.003
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
Z33 Pregnant state, incidental	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
O14.0 Moderate preeclampsia	0.000	0.997	0.003
I45.8 Other specified conduction disorders	0.000	0.997	0.002
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.997	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.002	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.997	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
I45.0 Right fascicular block	0.000	0.998	0.002
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
J94 Other pleural conditions	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.000	0.998	0.002
W25.9 Unspecified place	0.002	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.002	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.002	0.998	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.998	0.002
O15 Eclampsia	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.998	0.002
L40 Psoriasis	0.000	0.998	0.002
J98.1 Pulmonary collapse	0.002	0.998	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.998	0.002
O14.2 HELLP syndrome	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
C90.0 Multiple myeloma	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.998	0.002
M06.18 Adult-onset Still's disease (Other)	0.000	0.998	0.002
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.998	0.002
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.998	0.002
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.998	0.002
M06.14 Adult-onset Still's disease (Hand)	0.000	0.998	0.002
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.998	0.002
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.998	0.002
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.998	0.002
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.998	0.002
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.998	0.002
M06.28 Rheumatoid bursitis (Other)	0.000	0.998	0.002
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.998	0.002
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.998	0.002
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.998	0.002
M06.24 Rheumatoid bursitis (Hand)	0.000	0.998	0.002
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.998	0.002
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.998	0.002
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.998	0.002
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.998	0.002
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.998	0.002
M06.38 Rheumatoid nodule (Other)	0.000	0.998	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.998	0.002
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.998	0.002
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.998	0.002
M06.33 Rheumatoid nodule (Forearm)	0.000	0.998	0.002
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.998	0.002
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.998	0.002
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
J98.9 Respiratory disorder, unspecified	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
E87.5 Hyperkalaemia	0.002	0.998	0.000
I45.5 Other specified heart block	0.000	0.998	0.002
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
L40.0 Psoriasis vulgaris	0.000	0.998	0.002
I50 Heart failure	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.998	0.002
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
I45.3 Trifascicular block	0.000	0.998	0.002
I45.4 Nonspecific intraventricular block	0.000	0.998	0.002
O12.0 Gestational oedema	0.000	0.998	0.002
J94.2 Haemothorax	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.000	0.998	0.002
J93 Pneumothorax	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.002
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.002
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.998	0.002
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.002
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.002
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.002
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.998	0.002
D37.3 Appendix	0.002	0.998	0.000
J94.9 Pleural condition, unspecified	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
J94.1 Fibrothorax	0.002	0.998	0.000
J94.0 Chylous effusion	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.998	0.002
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.002	0.998	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.002	0.998	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.998	0.002
O15.2 Eclampsia in the puerperium	0.000	0.998	0.002
O15.1 Eclampsia in labour	0.000	0.998	0.002
O15.0 Eclampsia in pregnancy	0.000	0.998	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
L40.8 Other psoriasis	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.000	0.998	0.002
L40.3 Pustulosis palmaris et plantaris	0.000	0.998	0.002
L40.2 Acrodermatitis continua	0.000	0.998	0.002
L40.1 Generalised pustular psoriasis	0.000	0.998	0.002
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
J98 Other respiratory disorders	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.002
J98.8 Other specified respiratory disorders	0.002	0.998	0.000
H83.0 Labyrinthitis	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.998	0.001
J93.8 Other pneumothorax	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.000	0.998	0.001
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
L27.0 Generalised skin eruption due to drugs and medicaments	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.001	0.998	0.001
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
K63.1 Perforation of intestine (nontraumatic)	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
J98.5 Diseases of mediastinum, not elsewhere classified	0.002	0.998	0.000
J98.3 Compensatory emphysema	0.002	0.998	0.000
J98.2 Interstitial emphysema	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.002	0.998	0.000
R81 Glycosuria	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.000	0.998	0.002
R82 Other abnormal findings in urine	0.000	0.998	0.002
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
I20.8 Other forms of angina pectoris	0.002	0.998	0.000
D37.1 Stomach	0.001	0.998	0.000
W25 Contact with sharp glass	0.002	0.998	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.998	0.002
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
J98.6 Disorders of diaphragm	0.001	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.001
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.998	0.001
E03.8 Other specified hypothyroidism	0.000	0.998	0.001
M14.6 Neuropathic arthropathy	0.000	0.998	0.001
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
Q54 Hypospadias	0.001	0.998	0.000
Z46 Fitting and adjustment of other devices	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.001
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.001	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.001
E03 Other hypothyroidism	0.000	0.998	0.001
M14 Arthropathies in other diseases classified elsewhere	0.000	0.999	0.001
S02.30 Fracture of orbital floor (closed)	0.001	0.999	0.000
K05.6 Periodontal disease, unspecified	0.000	0.999	0.001
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.999	0.001
R82.4 Acetonuria	0.000	0.999	0.001
R82.3 Haemoglobinuria	0.000	0.999	0.001
R82.2 Biliuria	0.000	0.999	0.001
R82.1 Myoglobinuria	0.000	0.999	0.001
R82.0 Chyluria	0.000	0.999	0.001
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.001	0.999	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.999	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
W25.6 Industrial and construction area	0.001	0.999	0.000
W25.5 Trade and service area	0.001	0.999	0.000
W25.1 Residential institution	0.001	0.999	0.000
W25.0 Home	0.001	0.999	0.000
W25.8 Other specified place	0.001	0.999	0.000
W25.7 Farm	0.001	0.999	0.000
W25.4 Street and highway	0.001	0.999	0.000
W25.3 Sports and athletics area	0.001	0.999	0.000
W25.2 School, other institution and public administrative area	0.001	0.999	0.000
S02.11 Fracture of base of skull (open)	0.001	0.999	0.000
C90.3 Solitary plasmacytoma	0.001	0.999	0.000
C90.1 Plasma cell leukaemia	0.001	0.999	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.999	0.001
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
M24.54 Contracture of joint (Hand)	0.001	0.999	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.999	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.999	0.001
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
Y04.2 School, other institution and public administrative area	0.001	0.999	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.001	0.999	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
Q54.8 Other hypospadias	0.001	0.999	0.000
Q54.4 Congenital chordee	0.001	0.999	0.000
Q54.3 Hypospadias, perineal	0.001	0.999	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.999	0.000
Q54.1 Hypospadias, penile	0.001	0.999	0.000
E03.5 Myxoedema coma	0.000	0.999	0.001
E03.4 Atrophy of thyroid (acquired)	0.000	0.999	0.001
E03.3 Postinfectious hypothyroidism	0.000	0.999	0.001
E03.1 Congenital hypothyroidism without goitre	0.000	0.999	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.999	0.001
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.001	0.999	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.001	0.999	0.000
Z46.1 Fitting and adjustment of hearing aid	0.001	0.999	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.999	0.001
C71.9 Brain, unspecified	0.000	0.999	0.001
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.999	0.001
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.999	0.001
M14.4 Arthropathy in amyloidosis	0.000	0.999	0.001
M14.3 Lipoid dermatoarthritis	0.000	0.999	0.001
M14.2 Diabetic arthropathy	0.000	0.999	0.001
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.999	0.001
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.999	0.001
R87.6 Abnormal cytological findings	0.000	0.999	0.001
L81 Other disorders of pigmentation	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.999	0.001
Q51.2 Other doubling of uterus	0.001	0.999	0.000
S02.4 Fracture of malar and maxillary bones	0.001	0.999	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.999	0.001
W25.09 Contact with sharp glass; Home; During unspecified activity	0.001	0.999	0.000
W25.03 Contact with sharp glass; Home; While engaged in other types of work	0.001	0.999	0.000
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities	0.001	0.999	0.000
W25.52 Contact with sharp glass; Trade and service area;While working for income	0.001	0.999	0.000
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income	0.001	0.999	0.000
M12 Other specific arthropathies	0.000	0.999	0.001
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.999	0.001
M08 Juvenile arthritis	0.000	0.999	0.001
S02 Fracture of skull and facial bones	0.001	0.999	0.000
C83.1 Small cleaved cell (diffuse)	0.001	0.999	0.000
L81.2 Freckles	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.000	0.999	0.001
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
G95.2 Cord compression, unspecified	0.000	0.999	0.001
H26.8 Other specified cataract	0.000	0.999	0.001
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.001	0.999	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.999	0.001
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.999	0.001
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
D48.1 Connective and other soft tissue	0.000	0.999	0.001
E05.8 Other thyrotoxicosis	0.000	0.999	0.001
E05.5 Thyroid crisis or storm	0.000	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.000	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.999	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.999	0.001
K11.8 Other diseases of salivary glands	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
S02.6 Fracture of mandible	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
W21.9 Unspecified place	0.001	0.999	0.000
Y04.8 Other specified place	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations