TreeWAS – Variant ID: rs12497655

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.80 Fractures of other parts of lower leg (closed)	0.799	0.201	0.000
S82.8 Fractures of other parts of lower leg	0.698	0.302	0.000
S82 Fracture of lower leg, including ankle	0.587	0.413	0.000
S82.81 Fractures of other parts of lower leg (open)	0.568	0.432	0.000
S82.1 Fracture of upper end of tibia	0.566	0.434	0.000
S82.10 Fracture of upper end of tibia (closed)	0.552	0.448	0.000
S82.86 Maisonneuve's fracture	0.500	0.500	0.000
S82.9 Fracture of lower leg, part unspecified	0.469	0.531	0.000
S82.3 Fracture of lower end of tibia	0.466	0.534	0.000
S82.2 Fracture of shaft of tibia	0.457	0.543	0.000
S82.11 Fracture of upper end of tibia (open)	0.408	0.592	0.000
S80-S89 Injuries to the knee and lower leg	0.408	0.592	0.000
S82.31 Fracture of lower end of tibia (open)	0.408	0.592	0.000
S82.7 Multiple fractures of lower leg	0.397	0.602	0.000
S82.21 Fracture of shaft of tibia (open)	0.386	0.614	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.384	0.616	0.000
S89 Other and unspecified injuries of lower leg	0.379	0.621	0.000
S82.4 Fracture of fibula alone	0.375	0.625	0.000
S89.9 Unspecified injury of lower leg	0.364	0.636	0.000
S84 Injury of nerves at lower leg level	0.348	0.651	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.336	0.664	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.306	0.694	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.303	0.697	0.000
S82.5 Fracture of medial malleolus	0.298	0.702	0.000
S88 Traumatic amputation of lower leg	0.292	0.707	0.000
S87 Crushing injury of lower leg	0.292	0.707	0.000
S85 Injury of blood vessels at lower leg level	0.292	0.707	0.000
S86 Injury of muscle and tendon at lower leg level	0.291	0.709	0.000
S82.6 Fracture of lateral malleolus	0.289	0.711	0.000
S82.20 Fracture of shaft of tibia (closed)	0.288	0.712	0.000
S82.71 Multiple fractures of lower leg (open)	0.285	0.715	0.000
S82.30 Fracture of lower end of tibia (closed)	0.273	0.727	0.000
S89.7 Multiple injuries of lower leg	0.272	0.728	0.000
S89.1 Other specified injuries of lower leg	0.272	0.728	0.000
S89.0 Multiple injuries of lower leg	0.272	0.728	0.000
S82.41 Fracture of fibula alone (open)	0.269	0.731	0.000
S82.0 Fracture of patella	0.268	0.732	0.000
S80 Superficial injury of lower leg	0.267	0.733	0.000
S82.70 Multiple fractures of lower leg (closed)	0.262	0.738	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.252	0.748	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.250	0.750	0.000
S84.8 Injury of other nerves at lower leg level	0.250	0.750	0.000
S84.7 Injury of multiple nerves at lower leg level	0.250	0.750	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.250	0.750	0.000
S84.0 Injury of tibial nerve at lower leg level	0.250	0.750	0.000
S89.8 Other specified injuries of lower leg	0.245	0.755	0.000
S80.0 Contusion of knee	0.241	0.759	0.000
S83.2 Tear of meniscus, current	0.240	0.760	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.231	0.769	0.000
S82.40 Fracture of fibula alone (closed)	0.223	0.777	0.000
S83.7 Injury to multiple structures of knee	0.217	0.783	0.000
S83.1 Dislocation of knee	0.217	0.783	0.000
S83.0 Dislocation of patella	0.217	0.783	0.000
S82.51 Fracture of medial malleolus (open)	0.217	0.783	0.000
S83.3 Tear of articular cartilage of knee, current	0.216	0.784	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.212	0.788	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.210	0.790	0.000
S85.8 Injury of other blood vessels at lower leg level	0.210	0.790	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.210	0.790	0.000
S85.5 Injury of popliteal vein	0.210	0.790	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.210	0.790	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.210	0.790	0.000
S85.2 Injury of peroneal artery	0.210	0.790	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.210	0.790	0.000
S85.0 Injury of popliteal artery	0.210	0.790	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.210	0.790	0.000
S87.0 Crushing injury of knee	0.210	0.790	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.210	0.790	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.210	0.790	0.000
S88.0 Traumatic amputation at knee level	0.210	0.790	0.000
S86.0 Injury of Achilles tendon	0.209	0.791	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.209	0.791	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.209	0.791	0.000
S82.61 Fracture of lateral malleolus (open)	0.207	0.792	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.197	0.803	0.000
S80.7 Multiple superficial injuries of lower leg	0.194	0.806	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.194	0.806	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.188	0.811	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.176	0.824	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.169	0.831	0.000
S80.8 Other superficial injuries of lower leg	0.159	0.841	0.000
S81 Open wound of lower leg	0.153	0.847	0.000
S86.00 Unspecified injury of Achilles tendon	0.150	0.850	0.000
S82.00 Fracture of patella (closed)	0.139	0.861	0.000
S82.01 Fracture of patella (open)	0.134	0.865	0.001
S81.9 Open wound of lower leg, part unspecified	0.116	0.884	0.000
S81.7 Multiple open wounds of lower leg	0.098	0.902	0.000
S80.9 Superficial injury of lower leg, unspecified	0.092	0.907	0.000
S82.50 Fracture of medial malleolus (closed)	0.085	0.915	0.001
S82.60 Fracture of lateral malleolus (closed)	0.076	0.924	0.000
S81.8 Open wound of other parts of lower leg	0.071	0.929	0.000
S81.0 Open wound of knee	0.065	0.934	0.000
N05 Unspecified nephritic syndrome	0.015	0.985	0.000
N05.9 Unspecified	0.015	0.985	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.013	0.987	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.013	0.987	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.012	0.988	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.012	0.988	0.000
M54.59 Low back pain (Site unspecified)	0.000	0.989	0.011
N04 Nephrotic syndrome	0.011	0.989	0.000
N00-N08 Glomerular diseases	0.011	0.989	0.000
N05.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
N05.6 Dense deposit disease	0.011	0.989	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.011	0.989	0.000
N05.0 Minor glomerular abnormality	0.011	0.989	0.000
N05.8 Other	0.010	0.989	0.000
D37.5 Rectum	0.010	0.990	0.000
N04.1 Focal and segmental glomerular lesions	0.010	0.990	0.000
N04.9 Unspecified	0.010	0.990	0.000
N05.2 Diffuse membranous glomerulonephritis	0.009	0.990	0.000
Q28 Other congenital malformations of circulatory system	0.009	0.991	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.009	0.991	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.009	0.991	0.000
N00 Acute nephritic syndrome	0.009	0.991	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.009	0.991	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.009	0.991	0.000
Q21 Congenital malformations of cardiac septa	0.009	0.991	0.000
N04.2 Diffuse membranous glomerulonephritis	0.009	0.991	0.000
Q21.3 Tetralogy of Fallot	0.009	0.991	0.000
T91.3 Sequelae of injury of spinal cord	0.008	0.991	0.000
N04.0 Minor glomerular abnormality	0.008	0.992	0.000
N04.8 Other	0.008	0.992	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.008	0.992	0.000
N04.6 Dense deposit disease	0.008	0.992	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.008	0.992	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.008	0.992	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.008	0.992	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.008	0.992	0.000
N06 Isolated proteinuria with specified morphological lesion	0.008	0.992	0.000
N01 Rapidly progressive nephritic syndrome	0.008	0.992	0.000
Q21.1 Atrial septal defect	0.008	0.992	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.992	0.008
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.008	0.992	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.008	0.992	0.000
O36.8 Maternal care for other specified foetal problems	0.008	0.992	0.000
N02 Recurrent and persistent haematuria	0.008	0.992	0.000
Q28.3 Other malformations of cerebral vessels	0.008	0.992	0.000
T91 Sequelae of injuries of neck and trunk	0.008	0.992	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.008	0.992	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.008	0.992	0.000
S42.20 Fracture of upper end of humerus (closed)	0.008	0.992	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.007	0.993	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.007	0.993	0.000
Q24 Other congenital malformations of heart	0.007	0.993	0.000
N00.9 Unspecified	0.007	0.993	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.007	0.993	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.007	0.993	0.000
S42.2 Fracture of upper end of humerus	0.007	0.993	0.000
S43.0 Dislocation of shoulder joint	0.007	0.993	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.007	0.993	0.000
S42 Fracture of shoulder and upper arm	0.007	0.993	0.000
Q25 Congenital malformations of great arteries	0.007	0.993	0.000
S40-S49 Injuries to the shoulder and upper arm	0.007	0.993	0.000
D37.1 Stomach	0.007	0.993	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.007	0.993	0.000
S43.1 Dislocation of acromioclavicular joint	0.007	0.993	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.007	0.993	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.007	0.993	0.000
Q28.1 Other malformations of precerebral vessels	0.007	0.993	0.000
D37.9 Digestive organ, unspecified	0.007	0.993	0.000
N02.2 Diffuse membranous glomerulonephritis	0.007	0.993	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.006	0.993	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.006	0.993	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.006	0.993	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.006	0.993	0.000
N00.8 Other	0.006	0.993	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.006	0.993	0.000
N00.6 Dense deposit disease	0.006	0.993	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.993	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.993	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.993	0.000
N00.2 Diffuse membranous glomerulonephritis	0.006	0.993	0.000
N00.1 Focal and segmental glomerular lesions	0.006	0.993	0.000
N00.0 Minor glomerular abnormality	0.006	0.993	0.000
Q26 Congenital malformations of great veins	0.006	0.993	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.006	0.993	0.000
E11.1 With ketoacidosis	0.000	0.993	0.007
N08.8 Glomerular disorders in other diseases classified elsewhere	0.006	0.993	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.006	0.993	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.006	0.993	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
Q21.8 Other congenital malformations of cardiac septa	0.006	0.993	0.000
Q21.4 Aortopulmonary septal defect	0.006	0.993	0.000
Q21.2 Atrioventricular septal defect	0.006	0.993	0.000
N02.0 Minor glomerular abnormality	0.006	0.993	0.000
T91.1 Sequelae of fracture of spine	0.006	0.993	0.000
D37.6 Liver, gallbladder and bile ducts	0.006	0.994	0.000
S42.0 Fracture of clavicle	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.994	0.000
Q22.5 Ebstein's anomaly	0.006	0.994	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.006	0.994	0.000
S41 Open wound of shoulder and upper arm	0.006	0.994	0.000
F29 Unspecified nonorganic psychosis	0.000	0.994	0.006
Q22.1 Congenital pulmonary valve stenosis	0.006	0.994	0.000
D37.4 Colon	0.006	0.994	0.000
N01.9 Unspecified	0.006	0.994	0.000
N01.8 Other	0.006	0.994	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N01.6 Dense deposit disease	0.006	0.994	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N01.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N01.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N01.0 Minor glomerular abnormality	0.006	0.994	0.000
N06.9 Unspecified	0.006	0.994	0.000
N06.8 Other	0.006	0.994	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N06.6 Dense deposit disease	0.006	0.994	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N06.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N06.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N06.0 Minor glomerular abnormality	0.006	0.994	0.000
N07.9 Unspecified	0.006	0.994	0.000
N07.8 Other	0.006	0.994	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N07.6 Dense deposit disease	0.006	0.994	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N07.2 Diffuse membranous glomerulonephritis	0.006	0.994	0.000
N07.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
N07.0 Minor glomerular abnormality	0.006	0.994	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.006	0.994	0.000
E11.5 With peripheral circulatory complications	0.000	0.994	0.006
T31.0 Burns involving less than 10% of body surface	0.006	0.994	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.994	0.006
N03 Chronic nephritic syndrome	0.006	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
S42.00 Fracture of clavicle (closed)	0.006	0.994	0.000
D37.3 Appendix	0.006	0.994	0.000
E11.0 With coma	0.000	0.994	0.006
S41.1 Open wound of upper arm	0.006	0.994	0.000
Q21.0 Ventricular septal defect	0.006	0.994	0.000
Q24.5 Malformation of coronary vessels	0.006	0.994	0.000
Q25.4 Other congenital malformations of aorta	0.006	0.994	0.000
T31 Burns classified according to extent of body surface involved	0.006	0.994	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.006	0.994	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.006	0.994	0.000
N02.6 Dense deposit disease	0.006	0.994	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.006	0.994	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.006	0.994	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.006	0.994	0.000
N02.1 Focal and segmental glomerular lesions	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.006	0.994	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.006	0.994	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.006	0.994	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.006	0.994	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.006	0.994	0.000
S92.00 Fracture of calcaneus (closed)	0.006	0.994	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.006	0.994	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.006	0.994	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.006	0.994	0.000
Q22.6 Hypoplastic right heart syndrome	0.006	0.994	0.000
Q22.4 Congenital tricuspid stenosis	0.006	0.994	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.006	0.994	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.006	0.994	0.000
Q22.0 Pulmonary valve atresia	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
J38.3 Other diseases of vocal cords	0.006	0.994	0.000
S92.0 Fracture of calcaneus	0.006	0.994	0.000
Q24.6 Congenital heart block	0.005	0.994	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.994	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.994	0.000
Q24.2 Cor triatriatum	0.005	0.994	0.000
Q24.1 Levocardia	0.005	0.994	0.000
Q24.0 Dextrocardia	0.005	0.994	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.005	0.994	0.000
E11.4 With neurological complications	0.000	0.994	0.006
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.005	0.995	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.005	0.995	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.005	0.995	0.000
S43.2 Dislocation of sternoclavicular joint	0.005	0.995	0.000
S42.21 Fracture of upper end of humerus (open)	0.005	0.995	0.000
D37.2 Small intestine	0.005	0.995	0.000
N02.8 Other	0.005	0.995	0.000
S50-S59 Injuries to the elbow and forearm	0.005	0.995	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
Q25.3 Stenosis of aorta	0.005	0.995	0.000
S56 Injury of muscle and tendon at forearm level	0.005	0.995	0.000
S48 Traumatic amputation of shoulder and upper arm	0.005	0.995	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S44 Injury of nerves at shoulder and upper arm level	0.005	0.995	0.000
S47 Crushing injury of shoulder and upper arm	0.005	0.995	0.000
S97 Crushing injury of ankle and foot	0.005	0.995	0.000
M46 Other inflammatory spondylopathies	0.005	0.995	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.005	0.995	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.005	0.995	0.000
E11.3 With ophthalmic complications	0.000	0.995	0.005
S92.2 Fracture of other tarsal bone(s)	0.005	0.995	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.005	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
N03.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.005	0.995	0.000
T39.1 4-Aminophenol derivatives	0.005	0.995	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.005	0.995	0.000
Q25.1 Coarctation of aorta	0.005	0.995	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.005	0.995	0.000
S40 Superficial injury of shoulder and upper arm	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.005	0.995	0.000
E11.6 With other specified complications	0.000	0.995	0.005
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.005	0.995	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q20.6 Isomerism of atrial appendages	0.005	0.995	0.000
Q20.5 Discordant atrioventricular connexion	0.005	0.995	0.000
Q20.4 Double inlet ventricle	0.005	0.995	0.000
Q20.3 Discordant ventriculoarterial connexion	0.005	0.995	0.000
Q20.2 Double outlet left ventricle	0.005	0.995	0.000
Q20.1 Double outlet right ventricle	0.005	0.995	0.000
Q20.0 Common arterial trunk	0.005	0.995	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.005	0.995	0.000
Q26.8 Other congenital malformations of great veins	0.005	0.995	0.000
Q26.6 Portal vein-hepatic artery fistula	0.005	0.995	0.000
Q26.5 Anomalous portal venous connexion	0.005	0.995	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.005	0.995	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.1 Persistent left superior vena cava	0.005	0.995	0.000
Q26.0 Congenital stenosis of vena cava	0.005	0.995	0.000
S41.0 Open wound of shoulder	0.005	0.995	0.000
S42.01 Fracture of clavicle (open)	0.005	0.995	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.005	0.995	0.000
Q27.4 Congenital phlebectasia	0.005	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.995	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.005	0.995	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.005	0.995	0.000
Z87.8 Personal history of other specified conditions	0.005	0.995	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.005	0.995	0.000
M46.4 Discitis, unspecified	0.005	0.995	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.005	0.995	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
S42.4 Fracture of lower end of humerus	0.005	0.995	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
S92.4 Fracture of great toe	0.005	0.995	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.005	0.995	0.000
E11.8 With unspecified complications	0.000	0.995	0.005
T09 Other injuries of spine and trunk, level unspecified	0.005	0.995	0.000
T00-T07 Injuries involving multiple body regions	0.005	0.995	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
E11.7 With multiple complications	0.000	0.995	0.005
N03.8 Other	0.004	0.995	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.004	0.995	0.000
N03.6 Dense deposit disease	0.004	0.995	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.995	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.995	0.000
N03.2 Diffuse membranous glomerulonephritis	0.004	0.995	0.000
N03.0 Minor glomerular abnormality	0.004	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.004	0.995	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.995	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.995	0.000
T31.1 Burns involving 10-19% of body surface	0.004	0.995	0.000
S42.1 Fracture of scapula	0.004	0.995	0.000
S50 Superficial injury of forearm	0.005	0.995	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.004	0.995	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.995	0.005
S55 Injury of blood vessels at forearm level	0.004	0.995	0.000
S42.3 Fracture of shaft of humerus	0.004	0.995	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.005	0.995	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.004	0.995	0.000
T31.9 Burns involving 90% or more of body surface	0.004	0.996	0.000
T31.8 Burns involving 80-89% of body surface	0.004	0.996	0.000
T31.7 Burns involving 70-79% of body surface	0.004	0.996	0.000
T31.6 Burns involving 60-69% of body surface	0.004	0.996	0.000
T31.5 Burns involving 50-59% of body surface	0.004	0.996	0.000
T31.4 Burns involving 40-49% of body surface	0.004	0.996	0.000
T31.3 Burns involving 30-39% of body surface	0.004	0.996	0.000
T31.2 Burns involving 20-29% of body surface	0.004	0.996	0.000
T33-T35 Frostbite	0.004	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.004	0.996	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.004	0.996	0.000
S70-S79 Injuries to the hip and thigh	0.004	0.996	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.004	0.996	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
T32 Corrosions classified according to extent of body surface involved	0.004	0.996	0.000
T30 Burn and corrosion, body region unspecified	0.004	0.996	0.000
T29 Burns and corrosions of multiple body regions	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.004	0.996	0.000
S92.1 Fracture of talus	0.004	0.996	0.000
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
S43.4 Sprain and strain of shoulder joint	0.004	0.996	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.004	0.996	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
S59 Other and unspecified injuries of forearm	0.004	0.996	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.004	0.996	0.000
S93.1 Dislocation of toe(s)	0.004	0.996	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.004	0.996	0.000
S51 Open wound of forearm	0.004	0.996	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.004	0.996	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
S58 Traumatic amputation of forearm	0.004	0.996	0.000
S57 Crushing injury of forearm	0.004	0.996	0.000
T01 Open wounds involving multiple body regions	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
S50.9 Superficial injury of forearm, unspecified	0.004	0.996	0.000
M46.2 Osteomyelitis of vertebra	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.004	0.996	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.004	0.996	0.000
T09.3 Injury of spinal cord, level unspecified	0.004	0.996	0.000
T13 Other injuries of lower limb, level unspecified	0.004	0.996	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.004	0.996	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.004	0.996	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.004	0.996	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.004	0.996	0.000
S44.4 Injury of musculocutaneous nerve	0.004	0.996	0.000
S44.3 Injury of axillary nerve	0.004	0.996	0.000
S44.2 Injury of radial nerve at upper arm level	0.004	0.996	0.000
S44.1 Injury of median nerve at upper arm level	0.004	0.996	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.004	0.996	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.004	0.996	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.004	0.996	0.000
S45.2 Injury of axillary or brachial vein	0.004	0.996	0.000
S45.1 Injury of brachial artery	0.004	0.996	0.000
S45.0 Injury of axillary artery	0.004	0.996	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.004	0.996	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.004	0.996	0.000
S48.0 Traumatic amputation at shoulder joint	0.004	0.996	0.000
S97.0 Crushing injury of ankle	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
S70 Superficial injury of hip and thigh	0.004	0.996	0.000
M46.8 Other specified inflammatory spondylopathies	0.004	0.996	0.000
M46.5 Other infective spondylopathies	0.004	0.996	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.004	0.996	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.004	0.996	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.004	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
G82.5 Tetraplegia, unspecified	0.004	0.996	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.004	0.996	0.000
S93.0 Dislocation of ankle joint	0.004	0.996	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.004	0.996	0.000
S99.8 Other specified injuries of ankle and foot	0.004	0.996	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.004	0.996	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.004	0.996	0.000
S55.1 Injury of radial artery at forearm level	0.004	0.996	0.000
S54 Injury of nerves at forearm level	0.004	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S99.7 Multiple injuries of ankle and foot	0.004	0.996	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
H35.9 Retinal disorder, unspecified	0.004	0.996	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.004	0.996	0.000
M46.0 Spinal enthesopathy	0.004	0.996	0.000
S50.0 Contusion of elbow	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
Q12 Congenital lens malformations	0.004	0.996	0.000
S51.8 Open wound of other parts of forearm	0.004	0.996	0.000
S70.0 Contusion of hip	0.004	0.996	0.000
G82.2 Paraplegia, unspecified	0.004	0.996	0.000
Q12.0 Congenital cataract	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
T98 Sequelae of other and unspecified effects of external causes	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
S50.7 Multiple superficial injuries of forearm	0.004	0.996	0.000
T13.1 Open wound of lower limb, level unspecified	0.004	0.996	0.000
O62.2 Other uterine inertia	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.004	0.996	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations