TreeWAS – Variant ID: rs12518099

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G44.2 Tension-type headache	0.000	0.937	0.063
G44 Other headache syndromes	0.000	0.948	0.052
G40-G47 Episodic and paroxysmal disorders	0.000	0.951	0.049
G40 Epilepsy	0.000	0.951	0.049
G40.9 Epilepsy, unspecified	0.000	0.951	0.049
G47 Sleep disorders	0.000	0.954	0.046
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.954	0.046
G47.9 Sleep disorder, unspecified	0.000	0.954	0.046
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.957	0.043
G44.0 Cluster headache syndrome	0.000	0.958	0.042
G41 Status epilepticus	0.000	0.960	0.040
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.961	0.039
G44.1 Vascular headache, not elsewhere classified	0.000	0.962	0.038
G47.2 Disorders of the sleep-wake schedule	0.000	0.963	0.037
G47.4 Narcolepsy and cataplexy	0.000	0.963	0.037
G44.3 Chronic posttraumatic headache	0.000	0.964	0.036
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.965	0.035
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.966	0.034
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.966	0.034
G40.8 Other epilepsy	0.000	0.966	0.034
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.966	0.034
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.966	0.034
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.967	0.033
G41.0 Grand mal status epilepticus	0.000	0.968	0.032
G45.3 Amaurosis fugax	0.000	0.969	0.031
G41.9 Status epilepticus, unspecified	0.000	0.969	0.031
G41.8 Other status epilepticus	0.000	0.971	0.029
G41.2 Complex partial status epilepticus	0.000	0.971	0.029
G41.1 Petit mal status epilepticus	0.000	0.971	0.029
G47.8 Other sleep disorders	0.000	0.971	0.029
G45.4 Transient global amnesia	0.000	0.971	0.029
G40.5 Special epileptic syndromes	0.000	0.972	0.028
G46.4 Cerebellar stroke syndrome	0.000	0.973	0.026
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.974	0.026
G45.0 Vertebro-basilar artery syndrome	0.000	0.974	0.025
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.975	0.025
G46.6 Pure sensory lacunar syndrome	0.000	0.975	0.025
G46.5 Pure motor lacunar syndrome	0.000	0.975	0.025
G46.3 Brain stem stroke syndrome	0.000	0.975	0.025
G46.2 Posterior cerebral artery syndrome	0.000	0.975	0.025
G46.1 Anterior cerebral artery syndrome	0.000	0.975	0.025
G46.0 Middle cerebral artery syndrome	0.000	0.975	0.025
G44.8 Other specified headache syndromes	0.000	0.975	0.024
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.976	0.024
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.976	0.024
G46.7 Other lacunar syndromes	0.000	0.978	0.021
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.979	0.021
G43 Migraine	0.000	0.982	0.018
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.982	0.017
G47.3 Sleep apnoea	0.000	0.982	0.018
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.983	0.017
G43.1 Migraine with aura [classical migraine]	0.000	0.985	0.015
G43.2 Status migrainosus	0.000	0.986	0.013
G43.0 Migraine without aura [common migraine]	0.000	0.987	0.013
G43.3 Complicated migraine	0.000	0.988	0.012
H61.0 Perichondritis of external ear	0.000	0.989	0.011
G43.8 Other migraine	0.000	0.989	0.011
D36.7 Other specified sites	0.000	0.991	0.009
R40.0 Somnolence	0.000	0.991	0.009
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.994	0.006
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
K70.4 Alcoholic hepatic failure	0.006	0.994	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
R40 Somnolence, stupor and coma	0.000	0.995	0.005
C34.9 Bronchus or lung, unspecified	0.005	0.995	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.005	0.995	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
C34 Malignant neoplasm of bronchus and lung	0.005	0.995	0.000
C34.2 Middle lobe, bronchus or lung	0.004	0.996	0.000
R40.2 Coma, unspecified	0.000	0.996	0.004
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.996	0.004
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.996	0.004
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.996	0.004
S06.8 Other intracranial injuries	0.000	0.996	0.004
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
O70.1 Second degree perineal laceration during delivery	0.004	0.996	0.000
R40.1 Stupor	0.000	0.996	0.004
R68.8 Other specified general symptoms and signs	0.004	0.996	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.004	0.996	0.000
C32 Malignant neoplasm of larynx	0.004	0.996	0.000
C32.0 Glottis	0.004	0.996	0.000
D04.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
J92.9 Pleural plaque without asbestos	0.000	0.996	0.004
K70 Alcoholic liver disease	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
C34.8 Overlapping lesion of bronchus and lung	0.003	0.996	0.000
E11.4 With neurological complications	0.000	0.997	0.003
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
C34.0 Main bronchus	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
M24.2 Disorder of ligament	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
C33 Malignant neoplasm of trachea	0.003	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
J92 Pleural plaque	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
I84.4 External haemorrhoids with other complications	0.003	0.997	0.000
C31.0 Maxillary sinus	0.003	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.003	0.997	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.997	0.003
D04.7 Skin of lower limb, including hip	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
M24.28 Disorder of ligament (Other)	0.003	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
G83.1 Monoplegia of lower limb	0.000	0.997	0.003
G70-G73 Diseases of myoneural junction and muscle	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.003	0.997	0.000
C32.3 Laryngeal cartilage	0.003	0.997	0.000
C32.2 Subglottis	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
G72 Other myopathies	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.000	0.997	0.003
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
C69.3 Choroid	0.003	0.997	0.000
C30.0 Nasal cavity	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
G83 Other paralytic syndromes	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.002	0.997	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.997	0.000
C31.3 Sphenoidal sinus	0.002	0.997	0.000
C31.2 Frontal sinus	0.002	0.997	0.000
C31.1 Ethmoidal sinus	0.002	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
Chapter VI Diseases of the nervous system	0.000	0.997	0.003
G70 Myasthenia gravis and other myoneural disorders	0.000	0.997	0.003
C32.1 Supraglottis	0.003	0.997	0.000
M24.29 Disorder of ligament (Site unspecified)	0.002	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.997	0.000
G83.2 Monoplegia of upper limb	0.000	0.997	0.003
H61 Other disorders of external ear	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
C38.4 Pleura	0.002	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.003	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.997	0.003
N89.5 Stricture and atresia of vagina	0.003	0.997	0.000
D68 Other coagulation defects	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.997	0.003
D04 Carcinoma in situ of skin	0.003	0.997	0.000
G71 Primary disorders of muscles	0.000	0.997	0.002
C30.1 Middle ear	0.002	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.002	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
M24.26 Disorder of ligament (Lower leg)	0.002	0.997	0.000
R68 Other general symptoms and signs	0.002	0.997	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
C37 Malignant neoplasm of thymus	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.002	0.998	0.000
C38.3 Mediastinum, part unspecified	0.002	0.998	0.000
C38.2 Posterior mediastinum	0.002	0.998	0.000
C38.1 Anterior mediastinum	0.002	0.998	0.000
C38.0 Heart	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
Z93.2 Ileostomy status	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.998	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.998	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.998	0.002
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
R68.2 Dry mouth, unspecified	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
G72.3 Periodic paralysis	0.000	0.998	0.002
G72.2 Myopathy due to other toxic agents	0.000	0.998	0.002
G72.1 Alcoholic myopathy	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
M24.0 Loose body in joint	0.002	0.998	0.000
R68.3 Clubbing of fingers	0.002	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.002	0.998	0.000
G72.0 Drug-induced myopathy	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.998	0.002
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
G72.8 Other specified myopathies	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.000	0.998	0.002
G83.3 Monoplegia, unspecified	0.000	0.998	0.002
G83.0 Diplegia of upper limbs	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.000	0.998	0.002
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.000	0.998	0.002
G70.2 Congenital and developmental myasthenia	0.000	0.998	0.002
G70.1 Toxic myoneural disorders	0.000	0.998	0.002
G71.1 Myotonic disorders	0.000	0.998	0.002
S60.9 Superficial injury of wrist and hand, unspecified	0.002	0.998	0.000
G83.4 Cauda equina syndrome	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.002
G71.8 Other primary disorders of muscles	0.000	0.998	0.002
G71.2 Congenital myopathies	0.000	0.998	0.002
K29.1 Other acute gastritis	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.000	0.998	0.002
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.998	0.002
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.998	0.002
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.000	0.998	0.002
G73.6 Myopathy in metabolic diseases	0.000	0.998	0.002
G73.5 Myopathy in endocrine diseases	0.000	0.998	0.002
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.998	0.002
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.998	0.002
G73.1 Eaton-Lambert syndrome	0.000	0.998	0.002
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
G20-G26 Extrapyramidal and movement disorders	0.000	0.998	0.002
C69.0 Conjunctiva	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
C53.0 Endocervix	0.000	0.998	0.002
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.998	0.002
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.998	0.002
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.002	0.998	0.000
S06 Intracranial injury	0.000	0.998	0.002
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.998	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
D04.5 Skin of trunk	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.001	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.000	0.998	0.002
C53.1 Exocervix	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
G83.9 Paralytic syndrome, unspecified	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.002	0.998	0.000
S60.1 Contusion of finger(s) with damage to nail	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
D36 Benign neoplasm of other and unspecified sites	0.000	0.998	0.002
G24 Dystonia	0.000	0.998	0.002
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.002	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.998	0.002
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.998	0.002
G25.5 Other chorea	0.000	0.998	0.002
G25.4 Drug-induced chorea	0.000	0.998	0.002
G25.1 Drug-induced tremor	0.000	0.998	0.002
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
I35.1 Aortic (valve) insufficiency	0.002	0.998	0.000
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
S56.2 Injury of other flexor muscle and tendon at forearm level	0.002	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.000	0.998	0.002
K82.8 Other specified diseases of gallbladder	0.002	0.998	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.002	0.998	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.998	0.002
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
Y95 Nosocomial condition	0.000	0.998	0.002
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.001
G71.0 Muscular dystrophy	0.000	0.998	0.001
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
G23 Other degenerative diseases of basal ganglia	0.000	0.998	0.002
G21 Secondary Parkinsonism	0.000	0.998	0.002
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.998	0.002
G22 Parkinsonism in diseases classified elsewhere	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.998	0.002
S50.8 Other superficial injuries of forearm	0.002	0.998	0.000
C69.9 Eye, unspecified	0.001	0.998	0.000
S60.0 Contusion of finger(s) without damage to nail	0.002	0.998	0.000
S50 Superficial injury of forearm	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.001	0.998	0.000
C71.4 Occipital lobe	0.001	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.001
G82.0 Flaccid paraplegia	0.000	0.998	0.001
I84.3 External thrombosed haemorrhoids	0.002	0.998	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.3 Focal brain injury	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
S53.4 Sprain and strain of elbow	0.002	0.998	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.998	0.001
G10 Huntington's disease	0.000	0.998	0.001
G30 Alzheimer's disease	0.000	0.998	0.002
I83 Varicose veins of lower extremities	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.998	0.000
M24.58 Contracture of joint (Other)	0.001	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.001	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.001	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.001	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
G81 Hemiplegia	0.000	0.998	0.002
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.998	0.001
G00.8 Other bacterial meningitis	0.000	0.998	0.001
G00.3 Staphylococcal meningitis	0.000	0.998	0.001
G00.2 Streptococcal meningitis	0.000	0.998	0.001
G00.0 Haemophilus meningitis	0.000	0.998	0.001
G24.8 Other dystonia	0.000	0.998	0.001
G96.9 Disorder of central nervous system, unspecified	0.001	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.001
S60.2 Contusion of other parts of wrist and hand	0.001	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.998	0.001
G11 Hereditary ataxia	0.000	0.998	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.001
D36.9 Benign neoplasm of unspecified site	0.000	0.998	0.001
G24.4 Idiopathic orofacial dystonia	0.000	0.998	0.001
G24.2 Idiopathic nonfamilial dystonia	0.000	0.998	0.001
G24.1 Idiopathic familial dystonia	0.000	0.998	0.001
G24.0 Drug-induced dystonia	0.000	0.998	0.001
G82.1 Spastic paraplegia	0.000	0.998	0.001
H61.9 Disorder of external ear, unspecified	0.001	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations