TreeWAS – Variant ID: rs12538707

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.000	1.000
K80 Cholelithiasis	0.000	0.000	1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.000	1.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.000	1.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.000	1.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.001	0.999
K81 Cholecystitis	0.000	0.001	0.999
K86 Other diseases of pancreas	0.000	0.008	0.992
K81.9 Cholecystitis, unspecified	0.000	0.009	0.991
K83 Other diseases of biliary tract	0.000	0.011	0.989
K83.8 Other specified diseases of biliary tract	0.000	0.021	0.979
K86.1 Other chronic pancreatitis	0.000	0.058	0.942
K86.2 Cyst of pancreas	0.000	0.065	0.935
K81.0 Acute cholecystitis	0.000	0.083	0.917
K85 Acute pancreatitis	0.000	0.103	0.897
K81.1 Chronic cholecystitis	0.000	0.115	0.885
K82 Other diseases of gallbladder	0.000	0.139	0.861
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.152	0.848
K80.4 Calculus of bile duct with cholecystitis	0.000	0.161	0.839
K85.1 Biliary acute pancreatitis	0.000	0.174	0.826
K83.0 Cholangitis	0.000	0.216	0.784
K83.9 Disease of biliary tract, unspecified	0.000	0.218	0.782
K81.8 Other cholecystitis	0.000	0.240	0.759
K83.1 Obstruction of bile duct	0.000	0.244	0.756
K86.3 Pseudocyst of pancreas	0.000	0.255	0.745
K82.2 Perforation of gallbladder	0.000	0.263	0.737
K86.9 Disease of pancreas, unspecified	0.000	0.279	0.721
K80.3 Calculus of bile duct with cholangitis	0.000	0.283	0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.283	0.717
K83.5 Biliary cyst	0.000	0.291	0.709
K83.3 Fistula of bile duct	0.000	0.291	0.709
K83.2 Perforation of bile duct	0.000	0.291	0.709
K82.8 Other specified diseases of gallbladder	0.000	0.308	0.692
K82.3 Fistula of gallbladder	0.000	0.315	0.685
K80.8 Other cholelithiasis	0.000	0.316	0.684
K85.2 Alcohol-induced acute pancreatitis	0.000	0.321	0.679
K85.3 Drug-induced acute pancreatitis	0.000	0.357	0.643
K85.0 Idiopathic acute pancreatitis	0.000	0.357	0.643
K85.9 Acute pancreatitis, unspecified	0.000	0.364	0.636
K86.8 Other specified diseases of pancreas	0.000	0.390	0.609
K82.4 Cholesterolosis of gallbladder	0.000	0.396	0.604
K82.9 Disease of gallbladder, unspecified	0.000	0.396	0.604
K82.0 Obstruction of gallbladder	0.000	0.397	0.602
K85.8 Other acute pancreatitis	0.000	0.402	0.597
K83.4 Spasm of sphincter of Oddi	0.000	0.454	0.546
K82.1 Hydrops of gallbladder	0.000	0.473	0.527
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.486	0.514
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.486	0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.486	0.514
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.074	0.926	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.073	0.927	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.069	0.931	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.069	0.931	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.064	0.936	0.000
O36.9 Maternal care for foetal problem, unspecified	0.063	0.937	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.063	0.937	0.000
O36 Maternal care for other known or suspected foetal problems	0.062	0.938	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.062	0.938	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.062	0.938	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.062	0.938	0.000
O26.8 Other specified pregnancy-related conditions	0.062	0.938	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.061	0.939	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.061	0.939	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.060	0.939	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.058	0.942	0.000
O16 Unspecified maternal hypertension	0.056	0.944	0.000
O14.9 Preeclampsia, unspecified	0.054	0.946	0.000
O40 Polyhydramnios	0.054	0.946	0.000
O48 Prolonged pregnancy	0.054	0.946	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.053	0.947	0.000
O36.1 Maternal care for other isoimmunisation	0.053	0.947	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.052	0.948	0.000
O26.2 Pregnancy care of habitual aborter	0.052	0.948	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.052	0.948	0.000
O30 Multiple gestation	0.051	0.949	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.051	0.949	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.051	0.949	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.050	0.950	0.000
K70 Alcoholic liver disease	0.000	0.950	0.050
O97 Death from sequelae of direct obstetric causes	0.049	0.950	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.049	0.950	0.000
O95 Obstetric death of unspecified cause	0.049	0.950	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.049	0.950	0.000
O28 Abnormal findings on antenatal screening of mother	0.049	0.951	0.000
O14.1 Severe preeclampsia	0.049	0.951	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.952	0.048
K70-K77 Diseases of liver	0.000	0.952	0.048
O26.0 Excessive weight gain in pregnancy	0.048	0.952	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.047	0.953	0.000
O44 Placenta praevia	0.047	0.953	0.000
O85-O92 Complications predominantly related to the puerperium	0.047	0.953	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.046	0.954	0.000
O22 Venous complications in pregnancy	0.046	0.954	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.046	0.954	0.000
O36.4 Maternal care for intra-uterine death	0.045	0.955	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.045	0.955	0.000
O26.5 Maternal hypotension syndrome	0.045	0.955	0.000
O26.4 Herpes gestationis	0.045	0.955	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.045	0.955	0.000
O26.1 Low weight gain in pregnancy	0.045	0.955	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.045	0.955	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.045	0.955	0.000
O36.2 Maternal care for hydrops foetalis	0.045	0.955	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.045	0.955	0.000
O24 Diabetes mellitus in pregnancy	0.045	0.955	0.000
O33 Maternal care for known or suspected disproportion	0.045	0.955	0.000
O20 Haemorrhage in early pregnancy	0.045	0.955	0.000
O29 Complications of anaesthesia during pregnancy	0.044	0.955	0.000
O25 Malnutrition in pregnancy	0.044	0.955	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.955	0.044
O31 Complications specific to multiple gestation	0.044	0.955	0.000
O15 Eclampsia	0.044	0.956	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.044	0.956	0.000
O45 Premature separation of placenta [abruptio placentae]	0.044	0.956	0.000
O36.6 Maternal care for excessive foetal growth	0.044	0.956	0.000
O30.0 Twin pregnancy	0.044	0.956	0.000
O36.8 Maternal care for other specified foetal problems	0.043	0.957	0.000
Chapter XI Diseases of the digestive system	0.000	0.957	0.043
K70.0 Alcoholic fatty liver	0.000	0.957	0.043
O41 Other disorders of amniotic fluid and membranes	0.043	0.957	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.958	0.042
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.042	0.958	0.000
O14.2 HELLP syndrome	0.042	0.958	0.000
K90-K93 Other diseases of the digestive system	0.000	0.958	0.042
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.040	0.960	0.000
O44.1 Placenta praevia with haemorrhage	0.040	0.960	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.960	0.040
O36.5 Maternal care for poor foetal growth	0.040	0.960	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.040	0.960	0.000
K70.4 Alcoholic hepatic failure	0.000	0.961	0.039
O34.1 Maternal care for tumour of corpus uteri	0.039	0.961	0.000
K92 Other diseases of digestive system	0.000	0.961	0.039
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.038	0.961	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.962	0.038
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.038	0.962	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.038	0.962	0.000
K92.1 Melaena	0.000	0.962	0.038
O26.9 Pregnancy-related condition, unspecified	0.038	0.962	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.038	0.962	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.038	0.962	0.000
K70.1 Alcoholic hepatitis	0.000	0.963	0.037
O30.9 Multiple gestation, unspecified	0.037	0.963	0.000
O30.8 Other multiple gestation	0.037	0.963	0.000
O30.2 Quadruplet pregnancy	0.037	0.963	0.000
O30.1 Triplet pregnancy	0.037	0.963	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.037	0.963	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.036	0.964	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.036	0.964	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.036	0.964	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.036	0.964	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.036	0.964	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.036	0.964	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.036	0.964	0.000
O12.0 Gestational oedema	0.036	0.964	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.964	0.036
O96.9 Death from unspecified obstetric cause	0.036	0.964	0.000
O96.1 Death from indirect obstetric cause	0.036	0.964	0.000
O96.0 Death from direct obstetric cause	0.036	0.964	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.036	0.964	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.036	0.964	0.000
O97.0 Death from sequelae of direct obstetric cause	0.036	0.964	0.000
O12.1 Gestational proteinuria	0.036	0.964	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.035	0.964	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.035	0.964	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.035	0.964	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.035	0.964	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.035	0.964	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.035	0.964	0.000
O34.4 Maternal care for other abnormalities of cervix	0.035	0.965	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.035	0.965	0.000
O34.0 Maternal care for congenital malformation of uterus	0.035	0.965	0.000
O14.0 Moderate preeclampsia	0.035	0.965	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.034	0.965	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.966	0.034
K71 Toxic liver disease	0.000	0.966	0.034
O46.8 Other antepartum haemorrhage	0.034	0.966	0.000
K90 Intestinal malabsorption	0.000	0.966	0.034
K72.9 Hepatic failure, unspecified	0.000	0.966	0.034
O12.2 Gestational oedema with proteinuria	0.034	0.966	0.000
O80-O84 Delivery	0.034	0.966	0.000
O89 Complications of anaesthesia during the puerperium	0.034	0.966	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.034	0.966	0.000
O87 Venous complications in the puerperium	0.034	0.966	0.000
O91 Infections of breast associated with childbirth	0.034	0.966	0.000
O88 Obstetric embolism	0.034	0.966	0.000
O85 Puerperal sepsis	0.034	0.966	0.000
K92.9 Disease of digestive system, unspecified	0.000	0.966	0.034
O21 Excessive vomiting in pregnancy	0.033	0.966	0.000
O23 Infections of genito-urinary tract in pregnancy	0.033	0.966	0.000
K75 Other inflammatory liver diseases	0.000	0.967	0.033
O22.9 Venous complication in pregnancy, unspecified	0.033	0.967	0.000
O22.8 Other venous complications in pregnancy	0.033	0.967	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.033	0.967	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.033	0.967	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.033	0.967	0.000
O22.1 Genital varices in pregnancy	0.033	0.967	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.967	0.033
K73 Chronic hepatitis, not elsewhere classified	0.000	0.967	0.033
K74.3 Primary biliary cirrhosis	0.000	0.967	0.033
O90 Complications of the puerperium, not elsewhere classified	0.033	0.967	0.000
O22.4 Haemorrhoids in pregnancy	0.033	0.967	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.032	0.967	0.000
O34.6 Maternal care for abnormality of vagina	0.032	0.967	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.032	0.967	0.000
O33.9 Maternal care for disproportion, unspecified	0.032	0.967	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.032	0.968	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.032	0.968	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.032	0.968	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.032	0.968	0.000
O33.8 Maternal care for disproportion of other origin	0.032	0.968	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.032	0.968	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.032	0.968	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.032	0.968	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.032	0.968	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.032	0.968	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.032	0.968	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.032	0.968	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.032	0.968	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.032	0.968	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.032	0.968	0.000
O29.6 Failed or difficult intubation during pregnancy	0.032	0.968	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.032	0.968	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.032	0.968	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.032	0.968	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.032	0.968	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.032	0.968	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.032	0.968	0.000
K72.1 Chronic hepatic failure	0.000	0.968	0.032
O31.8 Other complications specific to multiple gestation	0.032	0.968	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.032	0.968	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.032	0.968	0.000
O31.0 Papyraceous foetus	0.032	0.968	0.000
K74.0 Hepatic fibrosis	0.000	0.968	0.032
O15.9 Eclampsia, unspecified as to time period	0.032	0.968	0.000
O15.2 Eclampsia in the puerperium	0.032	0.968	0.000
O15.1 Eclampsia in labour	0.032	0.968	0.000
O15.0 Eclampsia in pregnancy	0.032	0.968	0.000
O45.8 Other premature separation of placenta	0.032	0.968	0.000
O45.0 Premature separation of placenta with coagulation defect	0.032	0.968	0.000
O45.9 Premature separation of placenta, unspecified	0.031	0.968	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.968	0.032
O34.8 Maternal care for other abnormalities of pelvic organs	0.031	0.968	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.031	0.969	0.000
O34.3 Maternal care for cervical incompetence	0.031	0.969	0.000
O41.0 Oligohydramnios	0.031	0.969	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.031	0.969	0.000
O41.1 Infection of amniotic sac and membranes	0.031	0.969	0.000
O20.8 Other haemorrhage in early pregnancy	0.031	0.969	0.000
O46.9 Antepartum haemorrhage, unspecified	0.031	0.969	0.000
O92.1 Cracked nipple associated with childbirth	0.030	0.970	0.000
K90.0 Coeliac disease	0.000	0.970	0.030
O86 Other puerperal infections	0.030	0.970	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.030	0.970	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.970	0.030
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.970	0.030
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.029	0.970	0.000
O47 False labour	0.029	0.971	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.029	0.971	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.029	0.971	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.029	0.971	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.029	0.971	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.029	0.971	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.971	0.029
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.971	0.029
K74.1 Hepatic sclerosis	0.000	0.971	0.029
O41.8 Other specified disorders of amniotic fluid and membranes	0.029	0.971	0.000
O43 Placental disorders	0.029	0.971	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.971	0.029
K92.8 Other specified diseases of digestive system	0.000	0.972	0.028
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.972	0.028
D86.0 Sarcoidosis of lung	0.000	0.972	0.028
O00-O08 Pregnancy with abortive outcome	0.027	0.972	0.000
K75.0 Abscess of liver	0.000	0.973	0.027
O44.0 Placenta praevia specified as without haemorrhage	0.027	0.973	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.973	0.027
D86 Sarcoidosis	0.000	0.973	0.027
O92.7 Other and unspecified disorders of lactation	0.027	0.973	0.000
O92.6 Galactorrhoea	0.027	0.973	0.000
O92.5 Suppressed lactation	0.027	0.973	0.000
O92.4 Hypogalactia	0.027	0.973	0.000
O92.3 Agalactia	0.027	0.973	0.000
O92.0 Retracted nipple associated with childbirth	0.027	0.973	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.026	0.974	0.000
C44.5 Skin of trunk	0.000	0.974	0.026
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.974	0.026
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.025	0.975	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.025	0.975	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.025	0.975	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.025	0.975	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.975	0.025
K71.8 Toxic liver disease with other disorders of liver	0.000	0.975	0.025
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.975	0.025
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.975	0.025
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.975	0.025
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.975	0.025
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.975	0.025
K71.2 Toxic liver disease with acute hepatitis	0.000	0.975	0.025
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.975	0.025
K71.0 Toxic liver disease with cholestasis	0.000	0.975	0.025
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.975	0.025
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.975	0.025
K91.3 Postoperative intestinal obstruction	0.000	0.975	0.025
K90.3 Pancreatic steatorrhoea	0.000	0.975	0.025
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.975	0.025
K90.1 Tropical sprue	0.000	0.975	0.025
K90.8 Other intestinal malabsorption	0.000	0.975	0.025
O84 Multiple delivery	0.025	0.975	0.000
O83 Other assisted single delivery	0.025	0.975	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.024	0.975	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.024	0.975	0.000
O89.6 Failed or difficult intubation during the puerperium	0.024	0.975	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.024	0.975	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.024	0.975	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.024	0.975	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.024	0.975	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.024	0.975	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.975	0.025
O90.1 Disruption of perineal obstetric wound	0.025	0.975	0.000
O87.2 Haemorrhoids in the puerperium	0.024	0.975	0.000
O87.9 Venous complication in the puerperium, unspecified	0.024	0.976	0.000
O87.8 Other venous complications in the puerperium	0.024	0.976	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.024	0.976	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.024	0.976	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.024	0.976	0.000
O88.8 Other obstetric embolism	0.024	0.976	0.000
O88.3 Obstetric pyaemic and septic embolism	0.024	0.976	0.000
O88.2 Obstetric blood-clot embolism	0.024	0.976	0.000
O88.1 Amniotic fluid embolism	0.024	0.976	0.000
O88.0 Obstetric air embolism	0.024	0.976	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.024	0.976	0.000
O91.1 Abscess of breast associated with childbirth	0.024	0.976	0.000
O91.0 Infection of nipple associated with childbirth	0.024	0.976	0.000
O21.8 Other vomiting complicating pregnancy	0.024	0.976	0.000
O21.2 Late vomiting of pregnancy	0.024	0.976	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.024	0.976	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.024	0.976	0.000
O23.2 Infections of urethra in pregnancy	0.024	0.976	0.000
O23.1 Infections of bladder in pregnancy	0.024	0.976	0.000
O23.0 Infections of kidney in pregnancy	0.024	0.976	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.976	0.024
K75.2 Nonspecific reactive hepatitis	0.000	0.976	0.024
K75.1 Phlebitis of portal vein	0.000	0.976	0.024
O47.0 False labour before 37 completed weeks of gestation	0.024	0.976	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.976	0.024
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.976	0.024
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.976	0.024
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.976	0.024
O60-O75 Complications of labour and delivery	0.024	0.976	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.976	0.024
K74.5 Biliary cirrhosis, unspecified	0.000	0.976	0.024
K73.9 Chronic hepatitis, unspecified	0.000	0.976	0.024
O03 Spontaneous abortion	0.024	0.976	0.000
O90.5 Postpartum thyroiditis	0.024	0.976	0.000
O90.4 Postpartum acute renal failure	0.024	0.976	0.000
O90.3 Cardiomyopathy in the puerperium	0.024	0.976	0.000
O90.0 Disruption of Caesarean section wound	0.024	0.976	0.000
O23.5 Infections of the genital tract in pregnancy	0.023	0.976	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.976	0.024
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.023	0.977	0.000
O90.2 Haematoma of obstetric wound	0.023	0.977	0.000
O82 Single delivery by Caesarean section	0.023	0.977	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.977	0.023
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.977	0.023
O86.0 Infection of obstetric surgical wound	0.022	0.977	0.000
O86.2 Urinary tract infection following delivery	0.022	0.978	0.000
O81 Single delivery by forceps and vacuum extractor	0.022	0.978	0.000
O86.8 Other specified puerperal infections	0.022	0.978	0.000
O86.3 Other genito-urinary tract infections following delivery	0.022	0.978	0.000
O86.1 Other infection of genital tract following delivery	0.022	0.978	0.000
O63 Long labour	0.022	0.978	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.978	0.022
K93.1 Megacolon in Chagas' disease	0.000	0.978	0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.978	0.022
D86.8 Sarcoidosis of other and combined sites	0.000	0.978	0.022
K91.1 Postgastric surgery syndromes	0.000	0.979	0.021
O21.0 Mild hyperemesis gravidarum	0.021	0.979	0.000
O90.9 Complication of the puerperium, unspecified	0.021	0.979	0.000
O43.9 Placental disorder, unspecified	0.021	0.979	0.000
O43.2 Morbidly adherent placenta	0.021	0.979	0.000
O43.0 Placental transfusion syndromes	0.021	0.979	0.000
K76 Other diseases of liver	0.000	0.979	0.021
O71 Other obstetric trauma	0.021	0.979	0.000
O03.9 Complete or unspecified, without complication	0.021	0.979	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.021	0.979	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.020	0.980	0.000
O07 Failed attempted abortion	0.020	0.980	0.000
O06 Unspecified abortion	0.020	0.980	0.000
O05 Other abortion	0.020	0.980	0.000
O01 Hydatidiform mole	0.020	0.980	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.980	0.020
D86.3 Sarcoidosis of skin	0.000	0.980	0.020
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.980	0.020
O80 Single spontaneous delivery	0.019	0.981	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.019	0.981	0.000
O74 Complications of anaesthesia during labour and delivery	0.019	0.981	0.000
O63.9 Long labour, unspecified	0.019	0.981	0.000
O20.0 Threatened abortion	0.019	0.981	0.000
O61 Failed induction of labour	0.019	0.981	0.000
K75.4 Autoimmune hepatitis	0.000	0.981	0.019
K92.0 Haematemesis	0.000	0.981	0.019
O64 Obstructed labour due to malposition and malpresentation of foetus	0.018	0.982	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.018	0.982	0.000
O42 Premature rupture of membranes	0.018	0.982	0.000
O63.1 Prolonged second stage (of labour)	0.018	0.982	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.018	0.982	0.000
O83.9 Assisted single delivery, unspecified	0.018	0.982	0.000
O83.8 Other specified assisted single delivery	0.018	0.982	0.000
O83.4 Destructive operation for delivery	0.018	0.982	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.018	0.982	0.000
O83.2 Other manipulation-assisted delivery	0.018	0.982	0.000
O83.1 Other assisted breech delivery	0.018	0.982	0.000
O83.0 Breech extraction	0.018	0.982	0.000
O84.9 Multiple delivery, unspecified	0.018	0.982	0.000
O84.8 Other multiple delivery	0.018	0.982	0.000
O84.2 Multiple delivery, all by Caesarean section	0.018	0.982	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.018	0.982	0.000
O84.0 Multiple delivery, all spontaneous	0.018	0.982	0.000
O21.9 Vomiting of pregnancy, unspecified	0.018	0.982	0.000
O82.1 Delivery by emergency Caesarean section	0.018	0.982	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.018	0.982	0.000
O03.4 Incomplete, without complication	0.018	0.982	0.000
O60 Preterm delivery	0.017	0.982	0.000
O03.7 Complete or unspecified, complicated by embolism	0.017	0.983	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.017	0.983	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.017	0.983	0.000
O03.3 Incomplete, with other and unspecified complications	0.017	0.983	0.000
O03.2 Incomplete, complicated by embolism	0.017	0.983	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.017	0.983	0.000
O86.4 Pyrexia of unknown origin following delivery	0.017	0.983	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.983	0.017
O63.0 Prolonged first stage (of labour)	0.017	0.983	0.000
O71.8 Other specified obstetric trauma	0.017	0.983	0.000
O82.8 Other single delivery by Caesarean section	0.017	0.983	0.000
O82.2 Delivery by Caesarean hysterectomy	0.017	0.983	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.983	0.017
O71.5 Other obstetric injury to pelvic organs	0.016	0.983	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.016	0.984	0.000
O72 Postpartum haemorrhage	0.016	0.984	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.016	0.984	0.000
O66 Other obstructed labour	0.016	0.984	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.016	0.984	0.000
O81.2 Mid-cavity forceps with rotation	0.016	0.984	0.000
O81.1 Mid-cavity forceps delivery	0.016	0.984	0.000
O81.3 Other and unspecified forceps delivery	0.016	0.984	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.016	0.984	0.000
O81.0 Low forceps delivery	0.016	0.984	0.000
O71.4 Obstetric high vaginal laceration alone	0.016	0.984	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.016	0.984	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.016	0.984	0.000
O61.1 Failed instrumental induction of labour	0.016	0.984	0.000
O43.1 Malformation of placenta	0.015	0.984	0.000
O82.0 Delivery by elective Caesarean section	0.015	0.984	0.000
O80.8 Other single spontaneous delivery	0.015	0.984	0.000
O64.1 Obstructed labour due to breech presentation	0.015	0.985	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.015	0.985	0.000
O04 Medical abortion	0.014	0.985	0.001
O62 Abnormalities of forces of labour	0.015	0.985	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.015	0.985	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.985	0.015
K76.4 Peliosis hepatis	0.000	0.985	0.015
K76.3 Infarction of liver	0.000	0.985	0.015
K76.2 Central haemorrhagic necrosis of liver	0.000	0.985	0.015
O71.9 Obstetric trauma, unspecified	0.015	0.985	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.015	0.985	0.000
O71.3 Obstetric laceration of cervix	0.015	0.985	0.000
O71.2 Postpartum inversion of uterus	0.015	0.985	0.000
O71.1 Rupture of uterus during labour	0.015	0.985	0.000
O71.0 Rupture of uterus before onset of labour	0.015	0.985	0.000
O71.7 Obstetric haematoma of pelvis	0.015	0.985	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.015	0.985	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.015	0.985	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.015	0.985	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.015	0.985	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.015	0.985	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.015	0.985	0.000
O65.0 Obstructed labour due to deformed pelvis	0.015	0.985	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.015	0.985	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.985	0.015
O01.9 Hydatidiform mole, unspecified	0.014	0.985	0.000
O01.1 Incomplete and partial hydatidiform mole	0.014	0.985	0.000
O01.0 Classical hydatidiform mole	0.014	0.985	0.000
O05.9 Complete or unspecified, without complication	0.014	0.985	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.014	0.985	0.000
O05.7 Complete or unspecified, complicated by embolism	0.014	0.985	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.014	0.985	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.014	0.985	0.000
O05.4 Incomplete, without complication	0.014	0.985	0.000
O05.3 Incomplete, with other and unspecified complications	0.014	0.985	0.000
O05.2 Incomplete, complicated by embolism	0.014	0.985	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.014	0.985	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.014	0.985	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations