TreeWAS – Variant ID: rs12543592

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D32.0 Cerebral meninges	0.116	0.884	0.000
D32.9 Meninges, unspecified	0.113	0.887	0.000
D32 Benign neoplasm of meninges	0.109	0.891	0.000
D32.1 Spinal meninges	0.067	0.933	0.000
S02.50 Fracture of tooth (closed)	0.024	0.976	0.000
O86.0 Infection of obstetric surgical wound	0.015	0.985	0.000
S02.5 Fracture of tooth	0.014	0.986	0.000
O86 Other puerperal infections	0.012	0.988	0.000
K62.8 Other specified diseases of anus and rectum	0.012	0.988	0.000
K81.1 Chronic cholecystitis	0.012	0.988	0.000
O86.1 Other infection of genital tract following delivery	0.011	0.989	0.000
S02.51 Fracture of tooth (open)	0.010	0.989	0.000
S02.00 Fracture of vault of skull (closed)	0.011	0.989	0.000
O86.4 Pyrexia of unknown origin following delivery	0.010	0.990	0.000
S42.10 Fracture of scapula (closed)	0.000	0.990	0.010
O86.8 Other specified puerperal infections	0.010	0.990	0.000
O86.3 Other genito-urinary tract infections following delivery	0.009	0.991	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.991	0.009
M51.2 Other specified intervertebral disk displacement	0.009	0.991	0.000
S02.0 Fracture of vault of skull	0.009	0.991	0.000
O86.2 Urinary tract infection following delivery	0.008	0.992	0.000
S02 Fracture of skull and facial bones	0.007	0.993	0.000
O85-O92 Complications predominantly related to the puerperium	0.007	0.993	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.993	0.007
O85 Puerperal sepsis	0.007	0.993	0.000
S02.01 Fracture of vault of skull (open)	0.006	0.993	0.000
S02.6 Fracture of mandible	0.006	0.993	0.000
O87 Venous complications in the puerperium	0.006	0.994	0.000
O16 Unspecified maternal hypertension	0.006	0.994	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.994	0.006
S02.60 Fracture of mandible (closed)	0.006	0.994	0.000
O87.2 Haemorrhoids in the puerperium	0.006	0.994	0.000
G62.8 Other specified polyneuropathies	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
O88 Obstetric embolism	0.005	0.995	0.000
J98.4 Other disorders of lung	0.005	0.995	0.000
O87.9 Venous complication in the puerperium, unspecified	0.005	0.995	0.000
S02.3 Fracture of orbital floor	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
S02.1 Fracture of base of skull	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.005	0.995	0.000
S02.61 Fracture of mandible (open)	0.005	0.995	0.000
S02.7 Multiple fractures involving skull and facial bones	0.005	0.995	0.000
O89 Complications of anaesthesia during the puerperium	0.005	0.995	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.005	0.995	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.005	0.995	0.000
S02.8 Fractures of other skull and facial bones	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O87.8 Other venous complications in the puerperium	0.005	0.995	0.000
S02.4 Fracture of malar and maxillary bones	0.005	0.995	0.000
I46.9 Cardiac arrest, unspecified	0.005	0.995	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.995	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.004	0.995	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.995	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.004	0.996	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.004
S42.1 Fracture of scapula	0.000	0.996	0.004
O90.9 Complication of the puerperium, unspecified	0.004	0.996	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
O91.0 Infection of nipple associated with childbirth	0.004	0.996	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.004	0.996	0.000
S02.11 Fracture of base of skull (open)	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
O88.8 Other obstetric embolism	0.004	0.996	0.000
O88.3 Obstetric pyaemic and septic embolism	0.004	0.996	0.000
O88.2 Obstetric blood-clot embolism	0.004	0.996	0.000
O88.1 Amniotic fluid embolism	0.004	0.996	0.000
O88.0 Obstetric air embolism	0.004	0.996	0.000
S62.61 Fracture of other finger (open)	0.004	0.996	0.000
S02.31 Fracture of orbital floor (open)	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.000
N84.2 Polyp of vagina	0.000	0.996	0.004
O90.5 Postpartum thyroiditis	0.004	0.996	0.000
O90.4 Postpartum acute renal failure	0.004	0.996	0.000
O90.3 Cardiomyopathy in the puerperium	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.004	0.996	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.004	0.996	0.000
K60.3 Anal fistula	0.004	0.996	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.004	0.996	0.000
O12.0 Gestational oedema	0.004	0.996	0.000
O90.2 Haematoma of obstetric wound	0.004	0.996	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.996	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.996	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.996	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.996	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.996	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.996	0.000
S02.2 Fracture of nasal bones	0.004	0.996	0.000
S02.30 Fracture of orbital floor (closed)	0.004	0.996	0.000
S02.81 Fractures of other skull and facial bones (open)	0.004	0.996	0.000
O15 Eclampsia	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
O12.2 Gestational oedema with proteinuria	0.004	0.996	0.000
G35 Multiple sclerosis	0.000	0.996	0.004
O90.0 Disruption of Caesarean section wound	0.003	0.996	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
S42.11 Fracture of scapula (open)	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
G62.9 Polyneuropathy, unspecified	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.997	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.997	0.003
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.003	0.997	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.997	0.003
G30.0 Alzheimer's disease with early onset	0.000	0.997	0.003
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.997	0.000
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.003	0.997	0.000
G30 Alzheimer's disease	0.000	0.997	0.003
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.997	0.003
O15.9 Eclampsia, unspecified as to time period	0.003	0.997	0.000
O15.2 Eclampsia in the puerperium	0.003	0.997	0.000
O15.1 Eclampsia in labour	0.003	0.997	0.000
O15.0 Eclampsia in pregnancy	0.003	0.997	0.000
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
V23.4 Driver injured in traffic accident	0.000	0.997	0.003
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.997	0.000
X45.0 Home	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.002	0.997	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
Z44.3 Fitting and adjustment of external breast prosthesis	0.000	0.997	0.003
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
H10 Conjunctivitis	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.998	0.001
O14.2 HELLP syndrome	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
G30.8 Other Alzheimer's disease	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.998	0.002
M51 Other intervertebral disk disorders	0.002	0.998	0.000
R52.2 Other chronic pain	0.002	0.998	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M51.4 Schmorl's nodes	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
M22.2 Patellofemoral disorders	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.998	0.002
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Z89 Acquired absence of limb	0.000	0.998	0.002
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
M51.3 Other specified intervertebral disk degeneration	0.002	0.998	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
V23.5 Passenger injured in traffic accident	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
N80.8 Other endometriosis	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.002
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
K81 Cholecystitis	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.998	0.002
F84.5 Asperger's syndrome	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.998	0.001
V23.3 Person injured while boarding or alighting	0.000	0.998	0.001
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.998	0.001
V23.1 Passenger injured in nontraffic accident	0.000	0.998	0.001
V23.0 Driver injured in nontraffic accident	0.000	0.998	0.001
J35 Chronic diseases of tonsils and adenoids	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q74.1 Congenital malformation of knee	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.002	0.998	0.000
X45 Accidental poisoning by and exposure to alcohol	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
R09.0 Asphyxia	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.001
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.001
N10-N16 Renal tubulo-interstitial diseases	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.001	0.998	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.001	0.998	0.000
O14.0 Moderate preeclampsia	0.001	0.998	0.000
Q40.1 Congenital hiatus hernia	0.001	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.001	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.998	0.000
Q83.1 Accessory breast	0.001	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
Q39.6 Diverticulum of oesophagus	0.001	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.998	0.000
Q45.1 Annular pancreas	0.001	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q83 Congenital malformations of breast	0.001	0.998	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.000	0.998	0.001
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.001	0.998	0.000
Q83.3 Accessory nipple	0.001	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.001
M89.82 Other specified disorders of bone (Upper arm)	0.001	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.001	0.998	0.000
N82.4 Other female intestinal-genital tract fistulae	0.000	0.998	0.001
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
M79.67 Pain in limb (Ankle and foot)	0.000	0.999	0.001
Q67.6 Pectus excavatum	0.001	0.999	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.999	0.001
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.999	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.999	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.999	0.001
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.999	0.001
K81.0 Acute cholecystitis	0.001	0.999	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.999	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.999	0.001
N82.0 Vesicovaginal fistula	0.000	0.999	0.001
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
Q77.4 Achondroplasia	0.001	0.999	0.000
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
X45.9 Unspecified place	0.001	0.999	0.000
X45.8 Other specified place	0.001	0.999	0.000
X45.7 Farm	0.001	0.999	0.000
X45.6 Industrial and construction area	0.001	0.999	0.000
X45.5 Trade and service area	0.001	0.999	0.000
X45.4 Street and highway	0.001	0.999	0.000
X45.3 Sports and athletics area	0.001	0.999	0.000
X45.2 School, other institution and public administrative area	0.001	0.999	0.000
X45.1 Residential institution	0.001	0.999	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.001	0.999	0.000
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
D12.9 Anus and anal canal	0.000	0.999	0.001
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.999	0.001
J11.0 Influenza with pneumonia, virus not identified	0.001	0.999	0.000
Q43.7 Persistent cloaca	0.001	0.999	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.999	0.000
Q43.5 Ectopic anus	0.001	0.999	0.000
Q43.4 Duplication of intestine	0.001	0.999	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.999	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.999	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.999	0.001
I84.2 Internal haemorrhoids without complication	0.001	0.999	0.000
Q38.1 Ankyloglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.999	0.000
Q39.8 Other congenital malformations of oesophagus	0.001	0.999	0.000
Q39.5 Congenital dilatation of oesophagus	0.001	0.999	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.001	0.999	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.001	0.999	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.001	0.999	0.000
Q39.0 Atresia of oesophagus without fistula	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
G36 Other acute disseminated demyelination	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
I84.4 External haemorrhoids with other complications	0.000	0.999	0.001
J35.2 Hypertrophy of adenoids	0.000	0.999	0.001
Q83.9 Congenital malformation of breast, unspecified	0.001	0.999	0.000
Q83.2 Absent nipple	0.001	0.999	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.999	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
N82.5 Female genital tract-skin fistulae	0.000	0.999	0.001
Q44.4 Choledochal cyst	0.001	0.999	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.999	0.001
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.999	0.001
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.999	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.999	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.999	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.999	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.999	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.999	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.999	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.999	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.999	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.999	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.999	0.000
Z98.1 Arthrodesis status	0.001	0.999	0.000
I46 Cardiac arrest	0.001	0.999	0.000
E16.1 Other hypoglycaemia	0.000	0.999	0.001
H49.2 Sixth [abducent] nerve palsy	0.001	0.999	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.999	0.001
N49.8 Inflammatory disorders of other specified male genital organs	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
S62.6 Fracture of other finger	0.001	0.999	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.001	0.999	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.999	0.001
X45.99 Accidental poisoning by and exposure to alcohol; Unspecified place ;During unspecified activity	0.001	0.999	0.000
N82.3 Fistula of vagina to large intestine	0.000	0.999	0.001
Q39.4 Oesophageal web	0.001	0.999	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.999	0.001
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.001	0.999	0.000
M79.60 Pain in limb (Multiple sites)	0.001	0.999	0.000
J15.4 Pneumonia due to other streptococci	0.001	0.999	0.000
M51.8 Other specified intervertebral disk disorders	0.001	0.999	0.000
Q43.3 Congenital malformations of intestinal fixation	0.001	0.999	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.999	0.001
H49.0 Third [oculomotor] nerve palsy	0.001	0.999	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.999	0.001
N14.3 Nephropathy induced by heavy metals	0.000	0.999	0.001
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.999	0.001
N14.0 Analgesic nephropathy	0.000	0.999	0.001
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.999	0.001
Q76.0 Spina bifida occulta	0.001	0.999	0.000
N82 Fistulae involving female genital tract	0.000	0.999	0.001
G36.9 Acute disseminated demyelination, unspecified	0.000	0.999	0.001
G36.8 Other specified acute disseminated demyelination	0.000	0.999	0.001
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.999	0.001
G36.0 Neuromyelitis optica [Devic]	0.000	0.999	0.001
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.999	0.001
Q38.6 Other congenital malformations of mouth	0.001	0.999	0.000
Q80.9 Congenital ichthyosis, unspecified	0.001	0.999	0.000
Q89 Other congenital malformations, not elsewhere classified	0.001	0.999	0.000
Q80 Congenital ichthyosis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations