TreeWAS – Variant ID: rs12547604

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70 Alcoholic liver disease	0.000	0.668	0.332
K70.3 Alcoholic cirrhosis of liver	0.000	0.671	0.329
K70.1 Alcoholic hepatitis	0.000	0.681	0.319
K70.9 Alcoholic liver disease, unspecified	0.000	0.689	0.311
K70.0 Alcoholic fatty liver	0.000	0.697	0.303
K70.4 Alcoholic hepatic failure	0.000	0.749	0.251
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.770	0.229
K70-K77 Diseases of liver	0.000	0.826	0.174
K76 Other diseases of liver	0.000	0.833	0.167
K76.6 Portal hypertension	0.000	0.834	0.166
K76.7 Hepatorenal syndrome	0.000	0.843	0.157
K73 Chronic hepatitis, not elsewhere classified	0.000	0.878	0.122
K71 Toxic liver disease	0.000	0.880	0.120
K76.5 Hepatic veno-occlusive disease	0.000	0.880	0.120
K76.4 Peliosis hepatis	0.000	0.880	0.120
K76.3 Infarction of liver	0.000	0.880	0.120
K76.2 Central haemorrhagic necrosis of liver	0.000	0.880	0.120
K72 Hepatic failure, not elsewhere classified	0.000	0.881	0.119
K77 Liver disorders in diseases classified elsewhere	0.000	0.883	0.116
K76.1 Chronic passive congestion of liver	0.000	0.884	0.116
K75 Other inflammatory liver diseases	0.000	0.894	0.106
K76.9 Liver disease, unspecified	0.000	0.901	0.099
K73.9 Chronic hepatitis, unspecified	0.000	0.904	0.096
K72.9 Hepatic failure, unspecified	0.000	0.905	0.095
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.910	0.090
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.912	0.088
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.912	0.088
K76.8 Other specified diseases of liver	0.000	0.913	0.087
K71.9 Toxic liver disease, unspecified	0.000	0.914	0.086
K71.8 Toxic liver disease with other disorders of liver	0.000	0.914	0.086
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.914	0.086
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.914	0.086
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.914	0.086
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.914	0.086
K71.2 Toxic liver disease with acute hepatitis	0.000	0.914	0.086
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.914	0.086
K71.0 Toxic liver disease with cholestasis	0.000	0.914	0.086
K72.1 Chronic hepatic failure	0.000	0.914	0.085
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.916	0.084
K74 Fibrosis and cirrhosis of liver	0.000	0.917	0.083
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.919	0.081
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.920	0.080
K75.4 Autoimmune hepatitis	0.000	0.921	0.079
K75.2 Nonspecific reactive hepatitis	0.000	0.924	0.076
K75.1 Phlebitis of portal vein	0.000	0.924	0.076
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.925	0.075
K75.9 Inflammatory liver disease, unspecified	0.000	0.927	0.073
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.931	0.069
K75.0 Abscess of liver	0.000	0.931	0.068
K72.0 Acute and subacute hepatic failure	0.000	0.937	0.063
K75.8 Other specified inflammatory liver diseases	0.000	0.938	0.062
K74.4 Secondary biliary cirrhosis	0.000	0.940	0.059
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.940	0.059
K74.1 Hepatic sclerosis	0.000	0.940	0.059
K74.5 Biliary cirrhosis, unspecified	0.000	0.941	0.059
K74.3 Primary biliary cirrhosis	0.000	0.942	0.058
K74.6 Other and unspecified cirrhosis of liver	0.000	0.952	0.048
K74.0 Hepatic fibrosis	0.000	0.959	0.041
I67.9 Cerebrovascular disease, unspecified	0.000	0.980	0.020
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.980	0.020
O02.1 Missed abortion	0.013	0.987	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.990	0.010
N13 Obstructive and reflux uropathy	0.000	0.990	0.010
C44.3 Skin of other and unspecified parts of face	0.010	0.990	0.000
N13.4 Hydroureter	0.000	0.991	0.009
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.991	0.009
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.992	0.008
N13.3 Other and unspecified hydronephrosis	0.000	0.992	0.008
J32 Chronic sinusitis	0.008	0.992	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.992	0.008
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.992	0.008
J32.9 Chronic sinusitis, unspecified	0.008	0.992	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.992	0.008
J32.2 Chronic ethmoidal sinusitis	0.007	0.993	0.000
J32.4 Chronic pansinusitis	0.007	0.993	0.000
N13.6 Pyonephrosis	0.000	0.993	0.007
J32.1 Chronic frontal sinusitis	0.007	0.993	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.993	0.007
I67 Other cerebrovascular diseases	0.000	0.993	0.007
J32.0 Chronic maxillary sinusitis	0.007	0.993	0.000
J32.3 Chronic sphenoidal sinusitis	0.007	0.993	0.000
J32.8 Other chronic sinusitis	0.007	0.993	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.993	0.007
N28.1 Cyst of kidney, acquired	0.000	0.994	0.006
N13.8 Other obstructive and reflux uropathy	0.000	0.994	0.006
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.994	0.006
O02 Other abnormal products of conception	0.006	0.994	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.994	0.006
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.995	0.005
I67.5 Moyamoya disease	0.000	0.995	0.005
I67.4 Hypertensive encephalopathy	0.000	0.995	0.005
I67.3 Progressive vascular leukoencephalopathy	0.000	0.995	0.005
T78.4 Allergy, unspecified	0.000	0.995	0.005
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.995	0.005
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.995	0.005
N28.0 Ischaemia and infarction of kidney	0.000	0.995	0.005
O02.0 Blighted ovum and nonhydatidiform mole	0.005	0.995	0.000
T78.3 Angioneurotic oedema	0.000	0.995	0.005
O02.9 Abnormal product of conception, unspecified	0.005	0.995	0.000
O02.8 Other specified abnormal products of conception	0.005	0.995	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.996	0.004
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.996	0.004
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.996	0.004
Z48.0 Attention to surgical dressings and sutures	0.004	0.996	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.996	0.004
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
E23.0 Hypopituitarism	0.000	0.996	0.004
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.996	0.004
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
Z60.2 Living alone	0.000	0.996	0.004
R13 Dysphagia	0.000	0.996	0.004
Z48.9 Surgical follow-up care, unspecified	0.004	0.996	0.000
N25-N29 Other disorders of kidney and ureter	0.000	0.997	0.003
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
M20.0 Deformity of finger(s)	0.003	0.997	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.997	0.003
N26 Unspecified contracted kidney	0.000	0.997	0.003
N10-N16 Renal tubulo-interstitial diseases	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
I67.2 Cerebral atherosclerosis	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
Z48 Other surgical follow-up care	0.003	0.997	0.000
N27 Small kidney of unknown cause	0.000	0.997	0.003
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.997	0.003
L40.0 Psoriasis vulgaris	0.000	0.997	0.003
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.997	0.003
N11 Chronic tubulo-interstitial nephritis	0.000	0.997	0.003
Z49.0 Preparatory care for dialysis	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
G96.1 Disorders of meninges, not elsewhere classified	0.003	0.997	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.997	0.003
M79.0 Rheumatism, unspecified	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
C73 Malignant neoplasm of thyroid gland	0.000	0.997	0.003
Z60 Problems related to social environment	0.000	0.997	0.003
N11.1 Chronic obstructive pyelonephritis	0.000	0.997	0.003
N25 Disorders resulting from impaired renal tubular function	0.000	0.997	0.003
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
T66-T78 Other and unspecified effects of external causes	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.997	0.002
N27.0 Small kidney, unilateral	0.000	0.997	0.002
Z60.9 Problem related to social environment, unspecified	0.000	0.997	0.003
I67.8 Other specified cerebrovascular diseases	0.000	0.997	0.003
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.997	0.002
T66 Unspecified effects of radiation	0.000	0.997	0.002
N10 Acute tubulo-interstitial nephritis	0.000	0.997	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.002
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.997	0.002
N15 Other renal tubulo-interstitial diseases	0.000	0.997	0.002
T68 Hypothermia	0.000	0.997	0.002
M79.08 Rheumatism, unspecified (Other)	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
T71 Asphyxiation	0.000	0.998	0.002
N27.9 Small kidney, unspecified	0.000	0.998	0.002
Z60.8 Other problems related to social environment	0.000	0.998	0.002
N27.1 Small kidney, bilateral	0.000	0.998	0.002
G96.0 Cerebrospinal fluid leak	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
M79.07 Rheumatism, unspecified (Ankle and foot)	0.000	0.998	0.002
M79.06 Rheumatism, unspecified (Lower leg)	0.000	0.998	0.002
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M79.04 Rheumatism, unspecified (Hand)	0.000	0.998	0.002
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.998	0.002
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.002
N41.1 Chronic prostatitis	0.000	0.998	0.002
J43.9 Emphysema, unspecified	0.000	0.998	0.002
N25.8 Other disorders resulting from impaired renal tubular function	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.998	0.002
Z60.4 Social exclusion and rejection	0.000	0.998	0.002
Z60.3 Acculturation difficulty	0.000	0.998	0.002
Z60.1 Atypical parenting situation	0.000	0.998	0.002
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
N25.1 Nephrogenic diabetes insipidus	0.000	0.998	0.002
N25.0 Renal osteodystrophy	0.000	0.998	0.002
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
T74 Maltreatment syndromes	0.000	0.998	0.002
T73 Effects of other deprivation	0.000	0.998	0.002
T69 Other effects of reduced temperature	0.000	0.998	0.002
T67 Effects of heat and light	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
M79.01 Rheumatism, unspecified (Shoulder region)	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.998	0.002
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.998	0.002
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.998	0.002
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.998	0.002
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.998	0.002
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.998	0.002
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
N76.4 Abscess of vulva	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.998	0.002
N14.3 Nephropathy induced by heavy metals	0.000	0.998	0.002
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.998	0.002
N14.0 Analgesic nephropathy	0.000	0.998	0.002
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
N29.0 Late syphilis of kidney	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.998	0.002
N15.1 Renal and perinephric abscess	0.000	0.998	0.002
N15.0 Balkan nephropathy	0.000	0.998	0.002
T75 Effects of other external causes	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.998	0.002
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.000	0.998	0.002
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
C44.4 Skin of scalp and neck	0.002	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.998	0.002
T70 Effects of air pressure and water pressure	0.001	0.998	0.001
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
S52.70 Multiple fractures of forearm (closed)	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
Z49 Care involving dialysis	0.000	0.998	0.002
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.002
T67.8 Other effects of heat and light	0.000	0.998	0.002
T67.7 Heat oedema	0.000	0.998	0.002
T67.6 Heat fatigue, transient	0.000	0.998	0.002
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.002
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.002
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.002
T67.2 Heat cramp	0.000	0.998	0.002
T67.1 Heat syncope	0.000	0.998	0.002
T67.0 Heatstroke and sunstroke	0.000	0.998	0.002
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.002
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.002
T69.1 Chilblains	0.000	0.998	0.002
T69.0 Immersion hand and foot	0.000	0.998	0.002
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.002
T73.8 Other effects of deprivation	0.000	0.998	0.002
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.002
T73.2 Exhaustion due to exposure	0.000	0.998	0.002
T73.1 Effects of thirst	0.000	0.998	0.002
T73.0 Effects of hunger	0.000	0.998	0.002
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.002
T74.8 Other maltreatment syndromes	0.000	0.998	0.002
T74.3 Psychological abuse	0.000	0.998	0.002
T74.2 Sexual abuse	0.000	0.998	0.002
T74.1 Physical abuse	0.000	0.998	0.002
T74.0 Neglect or abandonment	0.000	0.998	0.002
Q54 Hypospadias	0.000	0.998	0.002
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.000	0.998	0.001
Q54.0 Hypospadias, balanic	0.000	0.998	0.002
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
N30.0 Acute cystitis	0.000	0.998	0.002
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
Q53 Undescended testicle	0.000	0.998	0.002
J31.2 Chronic pharyngitis	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C44.9 Malignant neoplasm of skin, unspecified	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.998	0.002
T70.3 Caisson disease [decompression sickness]	0.001	0.998	0.001
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
T75.8 Other specified effects of external causes	0.000	0.998	0.002
T75.3 Motion sickness	0.000	0.998	0.002
T75.2 Effects of vibration	0.000	0.998	0.002
T75.0 Effects of lightning	0.000	0.998	0.002
H47.2 Optic atrophy	0.002	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.001	0.998	0.001
T70.8 Other effects of air pressure and water pressure	0.001	0.998	0.001
T70.4 Effects of high-pressure fluids	0.001	0.998	0.001
T70.2 Other and unspecified effects of high altitude	0.001	0.998	0.001
T70.1 Sinus barotrauma	0.001	0.998	0.001
T70.0 Otitic barotrauma	0.001	0.998	0.001
E34 Other endocrine disorders	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
T75.4 Effects of electric current	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.002
H18.4 Corneal degeneration	0.000	0.998	0.002
T75.1 Drowning and nonfatal submersion	0.000	0.998	0.001
C44 Other malignant neoplasms of skin	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
Z49.2 Other dialysis	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
M17.5 Other secondary gonarthrosis	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
Q54.8 Other hypospadias	0.000	0.998	0.001
Q54.4 Congenital chordee	0.000	0.998	0.001
Q54.3 Hypospadias, perineal	0.000	0.998	0.001
Q54.2 Hypospadias, penoscrotal	0.000	0.998	0.001
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.001
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.001
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.001
F52.2 Failure of genital response	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.001
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.001
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.001
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.001
Q51.4 Unicornate uterus	0.000	0.998	0.001
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.001
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.001
Q53.9 Undescended testicle, unspecified	0.000	0.998	0.001
Q53.2 Undescended testicle, bilateral	0.000	0.998	0.001
Q53.0 Ectopic testis	0.000	0.998	0.001
C50.3 Lower-inner quadrant of breast	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.000	0.998	0.001
H34.2 Other retinal artery occlusions	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.001	0.998	0.000
H47.6 Disorders of visual cortex	0.001	0.998	0.000
H47.5 Disorders of other visual pathways	0.001	0.998	0.000
H47.4 Disorders of optic chiasm	0.001	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.001	0.998	0.000
E34.5 Androgen resistance syndrome	0.000	0.998	0.001
E34.4 Constitutional tall stature	0.000	0.998	0.001
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.001
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.001
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.001
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
M54.35 Sciatica (Thoracolumbar region)	0.001	0.998	0.000
M54.34 Sciatica-Thoracic	0.001	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.001	0.998	0.000
M54.32 Sciatica-Cervical	0.001	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.001	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.001	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.001
I45.5 Other specified heart block	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.000	0.998	0.002
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.001
Q54.1 Hypospadias, penile	0.000	0.998	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.998	0.001
C44.8 Overlapping lesion of skin	0.001	0.999	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.999	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
J35.8 Other chronic diseases of tonsils and adenoids	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.000	0.999	0.001
H18.8 Other specified disorders of cornea	0.000	0.999	0.001
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.999	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.999	0.001
Q50.2 Congenital torsion of ovary	0.000	0.999	0.001
Q50.1 Developmental ovarian cyst	0.000	0.999	0.001
Q50.0 Congenital absence of ovary	0.000	0.999	0.001
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
C44.1 Skin of eyelid, including canthus	0.001	0.999	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.999	0.001
H11.0 Pterygium	0.000	0.999	0.001
H47.3 Other disorders of optic disk	0.001	0.999	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.999	0.001
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.999	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.999	0.001
K82.4 Cholesterolosis of gallbladder	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.000	0.999	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.999	0.001
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.999	0.001
O90.9 Complication of the puerperium, unspecified	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.000	0.999	0.001
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.999	0.001
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.999	0.001
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.999	0.001
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.999	0.000
Z58.8 Other problems related to physical environment	0.000	0.999	0.001
Z64.0 Problems related to unwanted pregnancy	0.000	0.999	0.001
B07 Viral warts	0.000	0.999	0.001
M43.12 Spondylolisthesis (Cervical region)	0.000	0.999	0.001
H18.2 Other corneal oedema	0.000	0.999	0.001
H18 Other disorders of cornea	0.000	0.999	0.001
Q52 Other congenital malformations of female genitalia	0.000	0.999	0.001
D48.7 Other specified sites	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.000	0.999	0.001
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.999	0.001
Q56.4 Indeterminate sex, unspecified	0.000	0.999	0.001
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.999	0.001
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.999	0.001
I07.1 Tricuspid insufficiency	0.000	0.999	0.001
E24 Cushing's syndrome	0.000	0.999	0.001
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.999	0.001
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.001	0.999	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
F33.0 Recurrent depressive disorder, current episode mild	0.001	0.999	0.000
M19.1 Posttraumatic arthrosis of other joints	0.000	0.999	0.001
O90 Complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
C44.6 Skin of upper limb, including shoulder	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.999	0.001
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.999	0.001
I97.1 Other functional disturbances following cardiac surgery	0.000	0.999	0.001
O90.0 Disruption of Caesarean section wound	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.999	0.001
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.999	0.001
H18.7 Other corneal deformities	0.000	0.999	0.001
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.999	0.001
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.999	0.001
Q52.7 Other congenital malformations of vulva	0.000	0.999	0.001
Q52.6 Congenital malformation of clitoris	0.000	0.999	0.001
Q52.4 Other congenital malformations of vagina	0.000	0.999	0.001
Q52.3 Imperforate hymen	0.000	0.999	0.001
Q52.2 Congenital rectovaginal fistula	0.000	0.999	0.001
Q52.1 Doubling of vagina	0.000	0.999	0.001
Q52.0 Congenital absence of vagina	0.000	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.001	0.999	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.001	0.999	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.999	0.001
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
B34.8 Other viral infections of unspecified site	0.000	0.999	0.001
D05.1 Intraductal carcinoma in situ	0.000	0.999	0.001
E24.8 Other Cushing's syndrome	0.000	0.999	0.001
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.999	0.001
E24.3 Ectopic ACTH syndrome	0.000	0.999	0.001
E24.1 Nelson's syndrome	0.000	0.999	0.001
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.999	0.001
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.999	0.001
J43.8 Other emphysema	0.000	0.999	0.001
O90.5 Postpartum thyroiditis	0.001	0.999	0.000
O90.4 Postpartum acute renal failure	0.001	0.999	0.000
O90.3 Cardiomyopathy in the puerperium	0.001	0.999	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.999	0.001
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.999	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.999	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.999	0.001
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.999	0.001
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
H18.9 Disorder of cornea, unspecified	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.999	0.001
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.999	0.001
Q55.5 Congenital absence and aplasia of penis	0.000	0.999	0.001
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.000	0.999	0.001
Q55.3 Atresia of vas deferens	0.000	0.999	0.001
Q55.1 Hypoplasia of testis and scrotum	0.000	0.999	0.001
Q55.0 Absence and aplasia of testis	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
E28 Ovarian dysfunction	0.000	0.999	0.001
J43 Emphysema	0.000	0.999	0.001
Z58 Problems related to physical environment	0.000	0.999	0.001
A41.9 Septicaemia, unspecified	0.000	0.999	0.001
O90.1 Disruption of perineal obstetric wound	0.001	0.999	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.999	0.001
M54.16 Radiculopathy (Lumbar region)	0.000	0.999	0.001
E24.2 Drug-induced Cushing's syndrome	0.000	0.999	0.001
E24.0 Pituitary-dependent Cushing's disease	0.000	0.999	0.001
M86.9 Osteomyelitis, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations