TreeWAS – Variant ID: rs1254774

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J84.1 Other interstitial pulmonary diseases with fibrosis	0.025	0.975	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.017	0.983	0.000
D73.0 Hyposplenism	0.016	0.984	0.000
T51.9 Alcohol, unspecified	0.000	0.986	0.014
T51.0 Ethanol	0.000	0.986	0.014
S43.0 Dislocation of shoulder joint	0.000	0.987	0.013
T51 Toxic effect of alcohol	0.000	0.987	0.013
Y42.7 Androgens and anabolic congeners	0.000	0.988	0.012
C90.0 Multiple myeloma	0.011	0.989	0.000
D73 Diseases of spleen	0.010	0.990	0.000
T51.8 Other alcohols	0.000	0.990	0.009
T51.3 Fusel oil	0.000	0.990	0.009
T51.2 2-Propanol	0.000	0.990	0.009
T51.1 Methanol	0.000	0.990	0.009
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.991	0.009
D73.4 Cyst of spleen	0.009	0.991	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.991	0.009
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.992	0.008
D73.3 Abscess of spleen	0.007	0.993	0.000
D73.2 Chronic congestive splenomegaly	0.007	0.993	0.000
D73.9 Disease of spleen, unspecified	0.007	0.993	0.000
D73.8 Other diseases of spleen	0.007	0.993	0.000
H57 Other disorders of eye and adnexa	0.007	0.993	0.000
D73.5 Infarction of spleen	0.007	0.993	0.000
H57.1 Ocular pain	0.007	0.993	0.000
D73.1 Hypersplenism	0.006	0.993	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.994	0.006
I60 Subarachnoid haemorrhage	0.000	0.994	0.006
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.994	0.006
K08.8 Other specified disorders of teeth and supporting structures	0.006	0.994	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.995	0.005
I60.8 Other subarachnoid haemorrhage	0.000	0.995	0.005
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.995	0.005
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.995	0.005
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.995	0.005
M67.2 Synovial hypertrophy, not elsewhere classified	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.995	0.005
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.996	0.004
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.996	0.004
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.996	0.004
Y40 Systemic antibiotics	0.000	0.996	0.004
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.996	0.004
J84 Other interstitial pulmonary diseases	0.004	0.996	0.000
Y40.0 Penicillins	0.000	0.996	0.004
H57.8 Other specified disorders of eye and adnexa	0.004	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.996	0.004
Y40.3 Macrolides	0.000	0.996	0.004
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.996	0.004
Y42.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.996	0.004
S43.4 Sprain and strain of shoulder joint	0.000	0.996	0.004
Y42.4 Oral contraceptives	0.000	0.996	0.004
M13.93 Arthritis, unspecified (Forearm)	0.004	0.996	0.000
K08.3 Retained dental root	0.004	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.996	0.004
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.996	0.004
Y40.6 Rifamycins	0.000	0.996	0.004
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.996	0.003
Y52 Agents primarily affecting the cardiovascular system	0.000	0.996	0.004
K08 Other disorders of teeth and supporting structures	0.004	0.996	0.000
H53.8 Other visual disturbances	0.000	0.997	0.003
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
O81.4 Vacuum extractor delivery	0.000	0.997	0.003
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.000	0.997	0.003
Y40.2 Chloramphenicol group	0.000	0.997	0.003
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.997	0.003
Y40.4 Tetracyclines	0.000	0.997	0.003
S43.2 Dislocation of sternoclavicular joint	0.000	0.997	0.003
H57.0 Anomalies of pupillary function	0.003	0.997	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.997	0.003
H06.2 Dysthyroid exophthalmos	0.000	0.997	0.003
K04.5 Chronic apical periodontitis	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.997	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
J84.0 Alveolar and parietoalveolar conditions	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
Y40.5 Aminoglycosides	0.000	0.997	0.003
T98.1 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.997	0.003
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.003	0.997	0.000
D35.2 Pituitary gland	0.000	0.997	0.003
K08.2 Atrophy of edentulous alveolar ridge	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.000	0.997	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.997	0.003
M25.96 Joint disorder, unspecified (Lower leg)	0.003	0.997	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
Y42.2 Antithyroid drugs	0.000	0.997	0.002
E23.0 Hypopituitarism	0.000	0.997	0.003
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
H02.0 Entropion and trichiasis of eyelid	0.003	0.997	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.997	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
J84.8 Other specified interstitial pulmonary diseases	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.000	0.997	0.002
Y52.1 Calcium-channel blockers	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.000	0.997	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
O62.3 Precipitate labour	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.997	0.000
J30.3 Other allergic rhinitis	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
E88 Other metabolic disorders	0.000	0.998	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.002
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
F12.1 Harmful use	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
Y41.4 Anthelminthics	0.000	0.998	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.998	0.002
N89.9 Noninflammatory disorder of vagina, unspecified	0.002	0.998	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
M67.0 Short Achilles tendon (acquired)	0.002	0.998	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
Y44.2 Anticoagulants	0.000	0.998	0.002
Y45.4 Antirheumatics	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.000	0.998	0.002
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.998	0.002
I86.1 Scrotal varices	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
Y58 Bacterial vaccines	0.000	0.998	0.002
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.002
O81.0 Low forceps delivery	0.000	0.998	0.002
R54 Senility	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
Z94.0 Kidney transplant status	0.002	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.000	0.998	0.002
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
Y41.0 Sulphonamides	0.000	0.998	0.002
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
M25.98 Joint disorder, unspecified (Other)	0.002	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.998	0.002
Y50.8 Other central nervous system stimulants	0.000	0.998	0.002
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.998	0.002
Y50.1 Opioid receptor antagonists	0.000	0.998	0.002
Y50.0 Analeptics	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
B34.9 Viral infection, unspecified	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
O04.9 Complete or unspecified, without complication	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
E88.8 Other specified metabolic disorders	0.000	0.998	0.002
Q63.0 Accessory kidney	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
C90.3 Solitary plasmacytoma	0.001	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
W21.9 Unspecified place	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.998	0.002
O81.2 Mid-cavity forceps with rotation	0.000	0.998	0.002
O81.1 Mid-cavity forceps delivery	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
J30 Vasomotor and allergic rhinitis	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
Y53.7 Emetics	0.000	0.998	0.002
Y53.5 Digestants	0.000	0.998	0.002
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.000	0.998	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.998	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.998	0.001
Y58.5 Diphtheria vaccine	0.000	0.998	0.001
Y58.4 Tetanus vaccine	0.000	0.998	0.001
Y58.3 Plague vaccine	0.000	0.998	0.001
Y58.2 Cholera vaccine	0.000	0.998	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.998	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.000	0.998	0.001
Y56.8 Other topical agents	0.000	0.998	0.001
Y56.7 Dental drugs, topically applied	0.000	0.998	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
Y56.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
Y56.2 Local astringents and local detergents	0.000	0.998	0.001
Y56.1 Antipruritics	0.000	0.998	0.001
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.998	0.001
Y44.7 Plasma substitutes	0.000	0.998	0.001
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.998	0.002
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.998	0.001
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.001
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.001
Y54.0 Mineralocorticoids	0.000	0.998	0.002
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
T56 Toxic effect of metals	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
F12.2 Dependence syndrome	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.998	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.998	0.001
Y47.4 Bromine compounds	0.000	0.998	0.001
Y47.3 Paraldehyde	0.000	0.998	0.001
Y47.2 Chloral derivatives	0.000	0.998	0.001
Y47.0 Barbiturates, not elsewhere classified	0.000	0.998	0.001
Y53.2 Stimulant laxatives	0.000	0.998	0.001
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.001
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.001
Y59.9 Vaccine or biological substance, unspecified	0.000	0.998	0.001
Y59.8 Other specified vaccines and biological substances	0.000	0.998	0.001
Y59.2 Protozoal vaccines	0.000	0.998	0.001
Y59.1 Rickettsial vaccines	0.000	0.998	0.001
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.998	0.001
T60 Toxic effect of pesticides	0.000	0.998	0.001
T57 Toxic effect of other inorganic substances	0.000	0.998	0.001
T54 Toxic effect of corrosive substances	0.000	0.998	0.001
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.998	0.001
T52 Toxic effect of organic solvents	0.000	0.998	0.001
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.998	0.001
T55 Toxic effect of soaps and detergents	0.000	0.998	0.001
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
M67.4 Ganglion	0.001	0.998	0.000
Y46.5 Valproic acid	0.000	0.998	0.001
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
E88.3 Tumour lysis syndrome	0.000	0.998	0.001
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.001
Y46.8 Antispasticity drugs	0.000	0.998	0.001
Y46.3 Deoxybarbiturates	0.000	0.998	0.001
Y46.1 Oxazolidinediones	0.000	0.998	0.001
Y46.0 Succinimides	0.000	0.998	0.001
Y54.7 Agents affecting calcification	0.000	0.998	0.001
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
Y55.5 Anticommon cold drugs	0.000	0.998	0.001
Y55.3 Antitussives	0.000	0.998	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
Y55.0 Oxytocic drugs	0.000	0.998	0.001
C90.2 Plasmacytoma, extramedullary	0.001	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
Y55.4 Expectorants	0.000	0.998	0.001
E06 Thyroiditis	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.001	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.001
C82.0 Small cleaved cell, follicular	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.001	0.998	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.002
Y46.7 Anti-Parkinsonism drugs	0.000	0.998	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.001
Y58.0 BCG vaccine	0.000	0.998	0.001
Y59.0 Viral vaccines	0.000	0.998	0.001
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.998	0.001
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.998	0.001
M95.5 Acquired deformity of pelvis	0.000	0.998	0.001
M95.2 Other acquired deformity of head	0.000	0.998	0.001
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
B34 Viral infection of unspecified site	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.001	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.001
Y44.5 Thrombolytic drugs	0.000	0.998	0.001
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.998	0.001
Y46.2 Hydantoin derivatives	0.000	0.998	0.001
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.001
M95.1 Cauliflower ear	0.000	0.998	0.001
T56.8 Other metals	0.000	0.998	0.001
Y44.6 Natural blood and blood products	0.000	0.998	0.001
Y46.6 Other and unspecified antiepileptics	0.000	0.998	0.001
Y54.5 Other diuretics	0.000	0.998	0.001
T62 Toxic effect of other noxious substances eaten as food	0.000	0.998	0.001
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.001
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.001
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
Y49.9 Psychotropic drug, unspecified	0.000	0.998	0.001
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.001
Y49.7 Psychostimulants with abuse potential	0.000	0.998	0.001
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.998	0.001
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.001
Y53.4 Other laxatives	0.000	0.998	0.001
T93 Sequelae of injuries of lower limb	0.001	0.998	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.001	0.999	0.000
B34.1 Enterovirus infection, unspecified	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.999	0.001
T56.9 Metal, unspecified	0.000	0.999	0.001
T56.7 Beryllium and its compounds	0.000	0.999	0.001
T56.6 Tin and its compounds	0.000	0.999	0.001
T56.5 Zinc and its compounds	0.000	0.999	0.001
T56.4 Copper and its compounds	0.000	0.999	0.001
T56.3 Cadmium and its compounds	0.000	0.999	0.001
T56.2 Chromium and its compounds	0.000	0.999	0.001
T56.1 Mercury and its compounds	0.000	0.999	0.001
T56.0 Lead and its compounds	0.000	0.999	0.001
Y54.3 Benzothiadiazine derivatives	0.000	0.999	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.999	0.001
C50.2 Upper-inner quadrant of breast	0.000	0.999	0.001
D22.0 Melanocytic naevi of lip	0.001	0.999	0.000
L71.1 Rhinophyma	0.000	0.999	0.001
M67.1 Other contracture of tendon (sheath)	0.001	0.999	0.000
R26.0 Ataxic gait	0.001	0.999	0.000
E06.9 Thyroiditis, unspecified	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.999	0.001
T52.9 Organic solvent, unspecified	0.000	0.999	0.001
T52.4 Ketones	0.000	0.999	0.001
T52.3 Glycols	0.000	0.999	0.001
T52.2 Homologues of benzene	0.000	0.999	0.001
T52.1 Benzene	0.000	0.999	0.001
T52.0 Petroleum products	0.000	0.999	0.001
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
Z22.3 Carrier of other specified bacterial diseases	0.000	0.999	0.001
B25 Cytomegaloviral disease	0.001	0.999	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.999	0.001
T65 Toxic effect of other and unspecified substances	0.000	0.999	0.001
Y43 Primarily systemic agents	0.000	0.999	0.001
M67.49 Ganglion, multiple sites	0.001	0.999	0.000
M67.45 Ganglion, hip	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
T52.8 Other organic solvents	0.000	0.999	0.001
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.000	0.999	0.001
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.000	0.999	0.001
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.000	0.999	0.001
T53.5 Chlorofluorocarbons	0.000	0.999	0.001
T53.4 Dichloromethane	0.000	0.999	0.001
T53.3 Tetrachloroethylene	0.000	0.999	0.001
T53.2 Trichloroethylene	0.000	0.999	0.001
T53.1 Chloroform	0.000	0.999	0.001
T53.0 Carbon tetrachloride	0.000	0.999	0.001
T54.3 Corrosive alkalis and alklali-like substances	0.000	0.999	0.001
T54.2 Corrosive acids and acid-like substances	0.000	0.999	0.001
T54.1 Other corrosive organic compounds	0.000	0.999	0.001
T54.0 Phenol and phenol homologues	0.000	0.999	0.001
T57.9 Inorganic substance, unspecified	0.000	0.999	0.001
T57.8 Other specified inorganic substances	0.000	0.999	0.001
T57.3 Hydrogen cyanide	0.000	0.999	0.001
T57.2 Manganese and its compounds	0.000	0.999	0.001
T57.1 Phosphorus and its compounds	0.000	0.999	0.001
T57.0 Arsenic and its compounds	0.000	0.999	0.001
T60.9 Pesticide, unspecified	0.000	0.999	0.001
T60.8 Other pesticides	0.000	0.999	0.001
T60.4 Rodenticides	0.000	0.999	0.001
T60.3 Herbicides and fungicides	0.000	0.999	0.001
T60.2 Other insecticides	0.000	0.999	0.001
T60.1 Halogenated insecticides	0.000	0.999	0.001
T60.0 Organophosphate and carbamate insecticides	0.000	0.999	0.001
T61.9 Toxic effect of unspecified seafood	0.000	0.999	0.001
T61.8 Toxic effect of other seafoods	0.000	0.999	0.001
T61.2 Other fish and shellfish poisoning	0.000	0.999	0.001
T61.1 Scombroid fish poisoning	0.000	0.999	0.001
T61.0 Ciguatera fish poisoning	0.000	0.999	0.001
Y45.1 Salicylates	0.000	0.999	0.001
Y59.3 Immunoglobulin	0.000	0.999	0.001
E06.5 Other chronic thyroiditis	0.001	0.999	0.000
J95.8 Other postprocedural respiratory disorders	0.001	0.999	0.000
T54.9 Corrosive substance, unspecified	0.000	0.999	0.001
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
B25.0 Cytomegaloviral pneumonitis	0.001	0.999	0.000
B34.8 Other viral infections of unspecified site	0.001	0.999	0.000
E06.4 Drug-induced thyroiditis	0.001	0.999	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.999	0.000
E06.0 Acute thyroiditis	0.001	0.999	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.999	0.001
M81.4 Drug-induced osteoporosis	0.000	0.999	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.000	0.999	0.001
B25.8 Other cytomegaloviral diseases	0.001	0.999	0.000
B34.3 Parvovirus infection, unspecified	0.001	0.999	0.000
B34.2 Coronavirus infection, unspecified	0.001	0.999	0.000
B34.0 Adenovirus infection, unspecified	0.001	0.999	0.000
E13.9 Without complications	0.000	0.999	0.001
Y47.1 Benzodiazepines	0.000	0.999	0.001
M19.96 Arthrosis, unspecified-Lower leg	0.001	0.999	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.999	0.001
N39.4 Other specified urinary incontinence	0.000	0.999	0.001
N92.1 Excessive and frequent menstruation with irregular cycle	0.001	0.999	0.000
Y48.5 Therapeutic gases	0.000	0.999	0.001
Y48.1 Parenteral anaesthetics	0.000	0.999	0.001
Y48.0 Inhaled anaesthetics	0.000	0.999	0.001
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
H27.0 Aphakia	0.000	0.999	0.001
T62.8 Other specified noxious substances eaten as food	0.000	0.999	0.001
T62.2 Other ingested (parts of) plant(s)	0.000	0.999	0.001
T62.1 Ingested berries	0.000	0.999	0.001
T62.0 Ingested mushrooms	0.000	0.999	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.999	0.001
B34.4 Papovirus infection, unspecified	0.001	0.999	0.000
S82.2 Fracture of shaft of tibia	0.001	0.999	0.000
Y43.2 Antineoplastic natural products	0.000	0.999	0.001
Z94.5 Skin transplant status	0.001	0.999	0.000
R80 Isolated proteinuria	0.001	0.999	0.000
T63 Toxic effect of contact with venomous animals	0.000	0.999	0.001
B25.2 Cytomegaloviral pancreatitis	0.001	0.999	0.000
B25.1 Cytomegaloviral hepatitis	0.001	0.999	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.999	0.001
F12.9 Unspecified mental and behavioural disorder	0.000	0.999	0.001
F12.8 Other mental and behavioural disorders	0.000	0.999	0.001
F12.7 Residual and late-onset psychotic disorder	0.000	0.999	0.001
F12.6 Amnesic syndrome	0.000	0.999	0.001
F12.5 Psychotic disorder	0.000	0.999	0.001
F12.4 Withdrawal state with delirium	0.000	0.999	0.001
F12.3 Withdrawal state	0.000	0.999	0.001
F12.0 Acute intoxication	0.000	0.999	0.001
M95.4 Acquired deformity of chest and rib	0.000	0.999	0.001
N13.5 Kinking and stricture of ureter without hydronephrosis	0.001	0.999	0.000
T65.8 Toxic effect of other specified substances	0.000	0.999	0.001
T65.6 Paints and dyes, not elsewhere classified	0.000	0.999	0.001
T65.5 Nitroglycerin and other nitric acids and esters	0.000	0.999	0.001
T65.4 Carbon disulphide	0.000	0.999	0.001
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.000	0.999	0.001
T65.2 Tobacco and nicotine	0.000	0.999	0.001
T65.1 Strychnine and its salts	0.000	0.999	0.001
T65.0 Cyanides	0.000	0.999	0.001
Y43.9 Primarily systemic agent, unspecified	0.000	0.999	0.001
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.999	0.001
Y43.6 Enzymes, not elsewhere classified	0.000	0.999	0.001
Y43.5 Acidifying and alkalising agents	0.000	0.999	0.001
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations