TreeWAS – Variant ID: rs12552818

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R94.5 Abnormal results of liver function studies	0.155	0.845	0.000
R94 Abnormal results of function studies	0.079	0.921	0.000
R94.4 Abnormal results of kidney function studies	0.064	0.936	0.000
R94.6 Abnormal results of thyroid function studies	0.058	0.942	0.000
R94.2 Abnormal results of pulmonary function studies	0.057	0.943	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.057	0.943	0.000
R94.7 Abnormal results of other endocrine function studies	0.057	0.943	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.057	0.943	0.000
R94.0 Abnormal results of function studies of central nervous system	0.057	0.943	0.000
M16.1 Other primary coxarthrosis	0.055	0.945	0.000
R94.3 Abnormal results of cardiovascular function studies	0.052	0.948	0.000
M16.3 Other dysplastic coxarthrosis	0.041	0.959	0.000
M16 Coxarthrosis [arthrosis of hip]	0.041	0.959	0.000
M16.7 Other secondary coxarthrosis	0.031	0.969	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.030	0.970	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.029	0.971	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.029	0.971	0.000
M16.5 Other posttraumatic coxarthrosis	0.025	0.974	0.000
M16.0 Primary coxarthrosis, bilateral	0.025	0.975	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.980	0.020
S82.10 Fracture of upper end of tibia (closed)	0.000	0.982	0.018
E53.8 Deficiency of other specified B group vitamins	0.000	0.983	0.017
M15-M19 Arthrosis	0.016	0.984	0.000
M79.66 Pain in limb (Lower leg)	0.000	0.985	0.015
H25.0 Senile incipient cataract	0.015	0.985	0.000
M15 Polyarthrosis	0.014	0.986	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.013	0.987	0.000
S42.2 Fracture of upper end of humerus	0.000	0.987	0.012
H25 Senile cataract	0.012	0.988	0.000
H25.9 Senile cataract, unspecified	0.012	0.988	0.000
M15.3 Secondary multiple arthrosis	0.011	0.989	0.000
H25.1 Senile nuclear cataract	0.011	0.989	0.000
M19 Other arthrosis	0.011	0.989	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.011	0.989	0.000
M15.9 Polyarthrosis, unspecified	0.010	0.989	0.000
M15.0 Primary generalised (osteo)arthrosis	0.010	0.989	0.000
M15.8 Other polyarthrosis	0.010	0.989	0.000
M15.4 Erosive (osteo)arthrosis	0.010	0.989	0.000
M15.1 Heberden's nodes (with arthropathy)	0.010	0.989	0.000
M17 Gonarthrosis [arthrosis of knee]	0.010	0.990	0.000
K76.9 Liver disease, unspecified	0.010	0.990	0.000
M19.2 Other secondary arthrosis	0.010	0.990	0.000
M17.0 Primary gonarthrosis, bilateral	0.010	0.990	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.991	0.009
M19.1 Posttraumatic arthrosis of other joints	0.009	0.991	0.000
H25.2 Senile cataract, morgagnian type	0.009	0.991	0.000
M18 Arthrosis of first carpometacarpal joint	0.009	0.991	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.991	0.009
C78.7 Secondary malignant neoplasm of liver	0.009	0.991	0.000
E53 Deficiency of other B group vitamins	0.000	0.991	0.009
H02.1 Ectropion of eyelid	0.000	0.991	0.009
M17.5 Other secondary gonarthrosis	0.008	0.992	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.008	0.992	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.008	0.992	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.008	0.992	0.000
M19.8 Other specified arthrosis	0.008	0.992	0.000
S82.1 Fracture of upper end of tibia	0.000	0.992	0.008
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.008	0.992	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.008	0.992	0.000
M15.99 Polyosteoarthritis, unspecified	0.008	0.992	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.008	0.992	0.000
M17.3 Other posttraumatic gonarthrosis	0.008	0.992	0.000
M16.9 Coxarthrosis, unspecified	0.008	0.992	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.008	0.992	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.008	0.992	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.007	0.993	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.007	0.993	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.007	0.993	0.000
M19.28 Other secondary arthrosis (Other)	0.007	0.993	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.007	0.993	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.007	0.993	0.000
M19.24 Other secondary arthrosis (Hand)	0.007	0.993	0.000
M19.23 Other secondary arthrosis (Forearm)	0.007	0.993	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.007	0.993	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.007	0.993	0.000
S42 Fracture of shoulder and upper arm	0.000	0.993	0.007
K76 Other diseases of liver	0.007	0.993	0.000
M19.0 Primary arthrosis of other joints	0.007	0.993	0.000
H25.8 Other senile cataract	0.007	0.993	0.000
Z34 Supervision of normal pregnancy	0.000	0.993	0.007
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.007	0.993	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.007	0.993	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.007	0.993	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.007	0.993	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.007	0.993	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.007	0.993	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.007	0.993	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.007	0.993	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.007	0.993	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.007	0.993	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.007	0.993	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.007	0.993	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.993	0.006
E53.1 Pyridoxine deficiency	0.000	0.993	0.006
E53.0 Riboflavin deficiency	0.000	0.993	0.006
S42.4 Fracture of lower end of humerus	0.000	0.994	0.006
Z34.8 Supervision of other normal pregnancy	0.000	0.994	0.006
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.006	0.994	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.994	0.006
K76.1 Chronic passive congestion of liver	0.006	0.994	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.006	0.994	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.006	0.994	0.000
M19.88 Other specified arthrosis (Other)	0.006	0.994	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.006	0.994	0.000
M19.86 Other specified arthrosis (Lower leg)	0.006	0.994	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.006	0.994	0.000
M19.84 Other specified arthrosis (Hand)	0.006	0.994	0.000
M19.83 Other specified arthrosis (Forearm)	0.006	0.994	0.000
M19.82 Other specified arthrosis (Upper arm)	0.006	0.994	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.006	0.994	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.006	0.994	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.994	0.006
M19.06 Primary arthrosis of other joints-Lower leg	0.006	0.994	0.000
M20.2 Hallux rigidus	0.006	0.994	0.000
K76.6 Portal hypertension	0.006	0.994	0.000
M17.9 Gonarthrosis, unspecified	0.006	0.994	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.994	0.006
K76.7 Hepatorenal syndrome	0.006	0.994	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.995	0.005
Z35 Supervision of high-risk pregnancy	0.000	0.995	0.005
K76.5 Hepatic veno-occlusive disease	0.005	0.995	0.000
K76.4 Peliosis hepatis	0.005	0.995	0.000
K76.3 Infarction of liver	0.005	0.995	0.000
K76.2 Central haemorrhagic necrosis of liver	0.005	0.995	0.000
M19.08 Primary arthrosis of other joints (Other)	0.005	0.995	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.005	0.995	0.000
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.995	0.005
Q65 Congenital deformities of hip	0.005	0.995	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.995	0.005
Z35.5 Supervision of elderly primigravida	0.000	0.995	0.005
S42.1 Fracture of scapula	0.000	0.995	0.005
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.995	0.005
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.995	0.005
M19.03 Primary arthrosis of other joints (Forearm)	0.005	0.995	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.005	0.995	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.995	0.005
M19.09 Primary arthrosis of other joints (Site unspecified)	0.005	0.995	0.000
K76.8 Other specified diseases of liver	0.005	0.995	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.995	0.004
S42.0 Fracture of clavicle	0.000	0.995	0.005
Z34.0 Supervision of normal first pregnancy	0.000	0.995	0.004
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.995	0.000
S42.3 Fracture of shaft of humerus	0.000	0.995	0.004
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.004	0.995	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.996	0.004
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.996	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.996	0.004
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.004	0.996	0.000
K70-K77 Diseases of liver	0.004	0.996	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.004	0.996	0.000
Z31 Procreative management	0.000	0.996	0.004
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.996	0.004
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.996	0.004
K70 Alcoholic liver disease	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.996	0.004
Z35.6 Supervision of very young primigravida	0.000	0.996	0.004
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.996	0.004
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.000	0.996	0.004
K70.1 Alcoholic hepatitis	0.004	0.996	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.996	0.004
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.996	0.004
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.000	0.996	0.004
Q74.1 Congenital malformation of knee	0.004	0.996	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.004	0.996	0.000
Z40 Prophylactic surgery	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.996	0.000
Z31.2 In vitro fertilisation	0.000	0.996	0.004
Z33 Pregnant state, incidental	0.000	0.996	0.004
M20.0 Deformity of finger(s)	0.004	0.996	0.000
S42.11 Fracture of scapula (open)	0.000	0.996	0.004
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.996	0.004
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.996	0.004
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Z31.4 Procreative investigation and testing	0.000	0.996	0.004
K72 Hepatic failure, not elsewhere classified	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.004	0.996	0.000
E87.5 Hyperkalaemia	0.000	0.996	0.004
L73.2 Hidradenitis suppurativa	0.004	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
S42.01 Fracture of clavicle (open)	0.000	0.996	0.003
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
M20 Acquired deformities of fingers and toes	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.996	0.004
K83.8 Other specified diseases of biliary tract	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.996	0.003
S42.31 Fracture of shaft of humerus (open)	0.000	0.996	0.003
Z40.8 Other prophylactic surgery	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
K70.4 Alcoholic hepatic failure	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.997	0.000
K77 Liver disorders in diseases classified elsewhere	0.003	0.997	0.000
K71 Toxic liver disease	0.003	0.997	0.000
Z31.9 Procreative management, unspecified	0.000	0.997	0.003
Z31.6 General counselling and advice on procreation	0.000	0.997	0.003
Z31.5 Genetic counselling	0.000	0.997	0.003
Z31.3 Other assisted fertilisation methods	0.000	0.997	0.003
Z31.1 Artifical insemination	0.000	0.997	0.003
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.997	0.003
S40 Superficial injury of shoulder and upper arm	0.000	0.997	0.003
Z32 Pregnancy examination and test	0.000	0.997	0.003
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
S41 Open wound of shoulder and upper arm	0.000	0.997	0.003
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Z38 Liveborn infants according to place of birth	0.000	0.997	0.003
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.997	0.003
Z40.9 Prophylactic surgery, unspecified	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.003	0.997	0.000
M20.1 Hallux valgus (acquired)	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.997	0.003
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
K72.1 Chronic hepatic failure	0.003	0.997	0.000
Z31.8 Other procreative management	0.000	0.997	0.003
Q53 Undescended testicle	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
S41.1 Open wound of upper arm	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.000	0.997	0.003
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.997	0.003
S44 Injury of nerves at shoulder and upper arm level	0.000	0.997	0.003
S47 Crushing injury of shoulder and upper arm	0.000	0.997	0.003
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.003	0.997	0.000
L73.9 Follicular disorder, unspecified	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
S42.00 Fracture of clavicle (closed)	0.000	0.997	0.003
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
K71.9 Toxic liver disease, unspecified	0.002	0.997	0.000
K71.8 Toxic liver disease with other disorders of liver	0.002	0.997	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.002	0.997	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.997	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.002	0.997	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.002	0.997	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.002	0.997	0.000
K71.2 Toxic liver disease with acute hepatitis	0.002	0.997	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.002	0.997	0.000
K71.0 Toxic liver disease with cholestasis	0.002	0.997	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.997	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.003	0.997	0.000
Z37 Outcome of delivery	0.000	0.997	0.003
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.997	0.002
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.997	0.002
L73 Other follicular disorders	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.002	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.997	0.003
S42.30 Fracture of shaft of humerus (closed)	0.000	0.997	0.002
K70.0 Alcoholic fatty liver	0.002	0.997	0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.000	0.997	0.002
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.997	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.997	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.997	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.000	0.997	0.002
S41.7 Multiple open wounds of shoulder and upper arm	0.000	0.997	0.002
S41.0 Open wound of shoulder	0.000	0.997	0.002
Z32.1 Pregnancy confirmed	0.000	0.997	0.002
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.997	0.002
Q39 Congenital malformations of oesophagus	0.002	0.997	0.000
Q55.6 Other congenital malformations of penis	0.002	0.997	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.997	0.003
Z38.8 Other multiple, unspecified as to place of birth	0.000	0.997	0.002
Z38.7 Other multiple, born outside hospital	0.000	0.997	0.002
Z38.6 Other multiple, born in hospital	0.000	0.997	0.002
Z38.5 Twin, unspecified as to place of birth	0.000	0.997	0.002
Z38.4 Twin, born outside hospital	0.000	0.997	0.002
Z38.3 Twin, born in hospital	0.000	0.997	0.002
Z38.2 Singleton, unspecified as to place of birth	0.000	0.997	0.002
Z38.1 Singleton, born outside hospital	0.000	0.997	0.002
S40.0 Contusion of shoulder and upper arm	0.000	0.997	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
Z39 Postpartum care and examination	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Z37.0 Single live birth	0.000	0.998	0.002
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
H25-H28 Disorders of lens	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.002	0.998	0.000
Z38.0 Singleton, born in hospital	0.000	0.998	0.002
Q17.5 Prominent ear	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations