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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12591452
log Bayes Factor = 11.8657
Chromosome 15   position 49,273,619  (GRCh37) Explore rs12591452 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E04.2 Non-toxic multinodular goitre
1.000 0.000 0.000
E04 Other non-toxic goitre
1.000 0.000 0.000
E04.9 Non-toxic goitre, unspecified
1.000 0.000 0.000
E04.1 Non-toxic single thyroid nodule
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.934 0.066 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.927 0.073 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.910 0.090 0.000
E04.0 Non-toxic diffuse goitre
0.866 0.134 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.850 0.150 0.000
E07 Other disorders of thyroid
0.776 0.224 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.759 0.241 0.000
E04.8 Other specified non-toxic goitre
0.717 0.283 0.000
E06 Thyroiditis
0.714 0.286 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.670 0.330 0.000
E00 Congenital iodine-deficiency syndrome
0.670 0.330 0.000
E05.5 Thyroid crisis or storm
0.664 0.335 0.000
E05.4 Thyrotoxicosis factitia
0.664 0.335 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.664 0.335 0.000
E07.9 Disorder of thyroid, unspecified
0.659 0.341 0.000
E05.9 Thyrotoxicosis, unspecified
0.620 0.380 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.612 0.388 0.000
E06.5 Other chronic thyroiditis
0.564 0.436 0.000
E07.8 Other specified disorders of thyroid
0.563 0.437 0.000
E07.1 Dyshormogenetic goitre
0.556 0.444 0.000
E07.0 Hypersecretion of calcitonin
0.556 0.444 0.000
E06.1 Subacute thyroiditis
0.543 0.457 0.000
E05.8 Other thyrotoxicosis
0.536 0.464 0.000
E06.9 Thyroiditis, unspecified
0.524 0.476 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.516 0.484 0.000
E06.4 Drug-induced thyroiditis
0.512 0.488 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.512 0.488 0.000
E06.0 Acute thyroiditis
0.512 0.488 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.480 0.519 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.480 0.519 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.480 0.519 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.480 0.519 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.480 0.519 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.480 0.519 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.480 0.519 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.480 0.519 0.000
E06.3 Autoimmune thyroiditis
0.448 0.552 0.000
E03 Other hypothyroidism
0.366 0.633 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.300 0.699 0.000
E03.5 Myxoedema coma
0.263 0.737 0.000
E03.4 Atrophy of thyroid (acquired)
0.263 0.737 0.000
E03.3 Postinfectious hypothyroidism
0.263 0.737 0.000
E03.1 Congenital hypothyroidism without goitre
0.263 0.737 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.263 0.737 0.000
E03.8 Other specified hypothyroidism
0.185 0.814 0.000
E89.0 Postprocedural hypothyroidism
0.055 0.945 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.028 0.972 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.023 0.977 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.021 0.979 0.000
L89.1 Stage II decubitus ulcer
0.000 0.980 0.020
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.020 0.980 0.000
E89.5 Postprocedural testicular hypofunction
0.020 0.980 0.000
E89.1 Postprocedural hypoinsulinaemia
0.020 0.980 0.000
L89 Decubitus ulcer
0.000 0.981 0.019
E89.4 Postprocedural ovarian failure
0.019 0.981 0.000
E89.2 Postprocedural hypoparathyroidism
0.019 0.981 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.019 0.981 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.981 0.019
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.983 0.017
L89.2 Stage III decubitus ulcer
0.000 0.984 0.016
F00 Dementia in Alzheimer's disease
0.016 0.984 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.016 0.984 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.016 0.984 0.000
F03 Unspecified dementia
0.016 0.984 0.000
E89.3 Postprocedural hypopituitarism
0.015 0.985 0.000
L89.3 Stage IV decubitus ulcer
0.000 0.985 0.015
F02 Dementia in other diseases classified elsewhere
0.014 0.986 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.014 0.986 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.014 0.986 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.013 0.987 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.013 0.987 0.000
F02.3 Dementia in Parkinson's disease
0.013 0.987 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.013 0.987 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.012 0.988 0.000
F09 Unspecified organic or symptomatic mental disorder
0.012 0.988 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.012 0.988 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.012 0.988 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.012 0.988 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.012 0.988 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.011 0.988 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.011 0.988 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.989 0.011
C82.3 Follicular lymphoma grade IIIa
0.011 0.989 0.000
C82.0 Small cleaved cell, follicular
0.011 0.989 0.000
F06.2 Organic delusional [schizophrenia-like] disorder
0.011 0.989 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.010 0.989 0.000
F02.2 Dementia in Huntington's disease
0.010 0.989 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.010 0.989 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.010 0.990 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.010 0.990 0.000
F01 Vascular dementia
0.010 0.990 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.010 0.990 0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.010 0.990 0.000
E70-E90 Metabolic disorders
0.010 0.990 0.000
F02.0 Dementia in Pick's disease
0.010 0.990 0.000
C82.6 Cutaneous follicle centre lymphoma
0.010 0.990 0.000
C82.5 Diffuse follicle centre lymphoma
0.010 0.990 0.000
C82.4 Follicular lymphoma grade IIIb
0.010 0.990 0.000
E40-E46 Malnutrition
0.010 0.990 0.000
F06.6 Organic emotionally labile [asthenic] disorder
0.010 0.990 0.000
F06.5 Organic dissociative disorder
0.010 0.990 0.000
F06.4 Organic anxiety disorder
0.010 0.990 0.000
F06.3 Organic mood [affective] disorders
0.010 0.990 0.000
F06.1 Organic catatonic disorder
0.010 0.990 0.000
F06.0 Organic hallucinosis
0.010 0.990 0.000
F07.2 Postconcussional syndrome
0.009 0.990 0.000
F07.0 Organic personality disorder
0.009 0.990 0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.009 0.991 0.000
F07.1 Postencephalitic syndrome
0.009 0.991 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.000 0.991 0.009
E83.4 Disorders of magnesium metabolism
0.009 0.991 0.000
E83 Disorders of mineral metabolism
0.009 0.991 0.000
E83.3 Disorders of phosphorus metabolism
0.009 0.991 0.000
F05.9 Delirium, unspecified
0.008 0.992 0.000
E70 Disorders of aromatic amino-acid metabolism
0.008 0.992 0.000
F01.1 Multi-infarct dementia
0.008 0.992 0.000
E46 Unspecified protein-energy malnutrition
0.008 0.992 0.000
C82.2 Large cell, follicular
0.008 0.992 0.000
E84 Cystic fibrosis
0.008 0.992 0.000
F01.8 Other vascular dementia
0.007 0.992 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.007 0.992 0.000
F01.2 Subcortical vascular dementia
0.007 0.992 0.000
F01.0 Vascular dementia of acute onset
0.007 0.992 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.007 0.992 0.000
E76 Disorders of glycosaminoglycan metabolism
0.007 0.992 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.007 0.992 0.000
E72 Other disorders of amino-acid metabolism
0.007 0.992 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.007 0.992 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.007 0.992 0.000
F05.8 Other delirium
0.007 0.992 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.007 0.993 0.000
E45 Retarded development following protein-energy malnutrition
0.007 0.993 0.000
E43 Unspecified severe protein-energy malnutrition
0.007 0.993 0.000
E42 Marasmic kwashiorkor
0.007 0.993 0.000
E41 Nutritional marasmus
0.007 0.993 0.000
E40 Kwashiorkor
0.007 0.993 0.000
E79 Disorders of purine and pyrimidine metabolism
0.007 0.993 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.007 0.993 0.000
F06.7 Mild cognitive disorder
0.007 0.993 0.000
E74 Other disorders of carbohydrate metabolism
0.007 0.993 0.000
F05.0 Delirium not superimposed on dementia, so described
0.007 0.993 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.007 0.993 0.000
E83.8 Other disorders of mineral metabolism
0.007 0.993 0.000
E83.2 Disorders of zinc metabolism
0.007 0.993 0.000
E83.0 Disorders of copper metabolism
0.007 0.993 0.000
F05.1 Delirium superimposed on dementia
0.007 0.993 0.000
E70.3 Albinism
0.007 0.993 0.000
E85 Amyloidosis
0.007 0.993 0.000
E73 Lactose intolerance
0.006 0.993 0.000
E80.2 Other porphyria
0.006 0.994 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.006 0.994 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.994 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.994 0.000
E70.2 Disorders of tyrosine metabolism
0.006 0.994 0.000
E70.1 Other hyperphenylalaninaemias
0.006 0.994 0.000
E70.0 Classical phenylketonuria
0.006 0.994 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.006 0.994 0.000
E80.6 Other disorders of bilirubin metabolism
0.006 0.994 0.000
E84.8 Cystic fibrosis with other manifestations
0.006 0.994 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.006 0.994 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.994 0.000
E71.3 Disorders of fatty-acid metabolism
0.005 0.994 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.005 0.994 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.005 0.994 0.000
E71.0 Maple-syrup-urine disease
0.005 0.994 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.005 0.994 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.005 0.994 0.000
E72.5 Disorders of glycine metabolism
0.005 0.994 0.000
E72.4 Disorders of ornithine metabolism
0.005 0.994 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.005 0.994 0.000
E72.2 Disorders of urea cycle metabolism
0.005 0.994 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.005 0.994 0.000
E72.0 Disorders of amino-acid transport
0.005 0.994 0.000
E75.6 Lipid storage disorder, unspecified
0.005 0.994 0.000
E75.5 Other lipid storage disorders
0.005 0.994 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.005 0.994 0.000
E75.3 Sphingolipidosis, unspecified
0.005 0.994 0.000
E75.2 Other sphingolipidosis
0.005 0.994 0.000
E75.1 Other gangliosidosis
0.005 0.994 0.000
E75.0 GM2 gangliosidosis
0.005 0.994 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.005 0.994 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.005 0.994 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.005 0.994 0.000
E76.2 Other mucopolysaccharidoses
0.005 0.994 0.000
E76.1 Mucopolysaccharidosis, type II
0.005 0.994 0.000
E76.0 Mucopolysaccharidosis, type I
0.005 0.994 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.005 0.994 0.000
E77.8 Other disorders of glycoprotein metabolism
0.005 0.994 0.000
E77.1 Defects in glycoprotein degradation
0.005 0.994 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.005 0.994 0.000
F01.9 Vascular dementia, unspecified
0.006 0.994 0.000
E85.4 Organ-limited amyloidosis
0.005 0.994 0.000
E44.1 Mild protein-energy malnutrition
0.005 0.994 0.000
E44.0 Moderate protein-energy malnutrition
0.005 0.994 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.005 0.994 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.005 0.994 0.000
E79.1 Lesch-Nyhan syndrome
0.005 0.994 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.005 0.995 0.000
E80.5 Crigler-Najjar syndrome
0.005 0.995 0.000
E80.3 Defects of catalase and peroxydase
0.005 0.995 0.000
E80.1 Porphyria cutanea tarda
0.005 0.995 0.000
E80.0 Hereditary erythropoietic porphyria
0.005 0.995 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.995 0.005
E85.8 Other amyloidosis
0.005 0.995 0.000
E88 Other metabolic disorders
0.005 0.995 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.005 0.995 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.005 0.995 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.005 0.995 0.000
E74.2 Disorders of galactose metabolism
0.005 0.995 0.000
E74.1 Disorders of fructose metabolism
0.005 0.995 0.000
E74.0 Glycogen storage disease
0.005 0.995 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.005 0.995 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.005 0.995 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.005 0.995 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.005 0.995 0.000
H65.3 Chronic mucoid otitis media
0.000 0.995 0.005
E50-E64 Other nutritional deficiencies
0.005 0.995 0.000
E73.8 Other lactose intolerance
0.005 0.995 0.000
E73.1 Secondary lactase deficiency
0.005 0.995 0.000
E73.0 Congenital lactase deficiency
0.005 0.995 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.995 0.005
E15 Nondiabetic hypoglycaemic coma
0.005 0.995 0.000
E88.2 Lipomatosis, not elsewhere classified
0.005 0.995 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.005 0.995 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.995 0.004
D51.2 Transcobalamin II deficiency
0.000 0.995 0.004
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.995 0.004
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.004 0.996 0.000
M86.9 Osteomyelitis, unspecified
0.004 0.996 0.000
E85.3 Secondary systemic amyloidosis
0.004 0.996 0.000
E83.5 Disorders of calcium metabolism
0.004 0.996 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.004 0.996 0.000
E65-E68 Obesity and other hyperalimentation
0.004 0.996 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.996 0.004
E88.3 Tumour lysis syndrome
0.004 0.996 0.000
E56 Other vitamin deficiencies
0.004 0.996 0.000
E73.9 Lactose intolerance, unspecified
0.004 0.996 0.000
E88.9 Metabolic disorder, unspecified
0.004 0.996 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.004 0.996 0.000
E63 Other nutritional deficiencies
0.004 0.996 0.000
E51 Thiamine deficiency
0.004 0.996 0.000
E50 Vitamin A deficiency
0.004 0.996 0.000
E60 Dietary zinc deficiency
0.004 0.996 0.000
E59 Dietary selenium deficiency
0.004 0.996 0.000
E54 Ascorbic acid deficiency
0.004 0.996 0.000
E52 Niacin deficiency [pellagra]
0.004 0.996 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.004 0.996 0.000
E88.8 Other specified metabolic disorders
0.004 0.996 0.000
E85.9 Amyloidosis, unspecified
0.004 0.996 0.000
H65 Nonsuppurative otitis media
0.000 0.996 0.004
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.003 0.996 0.000
E58 Dietary calcium deficiency
0.003 0.996 0.000
G45.4 Transient global amnesia
0.000 0.996 0.004
M86 Osteomyelitis
0.004 0.996 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.003 0.997 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.003 0.997 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.003 0.997 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.003 0.997 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.003 0.997 0.000
G30.9 Alzheimer's disease, unspecified
0.003 0.997 0.000
E56.1 Deficiency of vitamin K
0.003 0.997 0.000
J95.0 Tracheostomy malfunction
0.000 0.997 0.003
E67 Other hyperalimentation
0.003 0.997 0.000
E68 Sequelae of hyperalimentation
0.003 0.997 0.000
M86.8 Other osteomyelitis
0.003 0.997 0.000
E56.9 Vitamin deficiency, unspecified
0.003 0.997 0.000
E56.8 Deficiency of other vitamins
0.003 0.997 0.000
E56.0 Deficiency of vitamin E
0.003 0.997 0.000
R15 Faecal incontinence
0.000 0.997 0.003
J95.8 Other postprocedural respiratory disorders
0.000 0.997 0.003
X23.9 Unspecified place
0.000 0.997 0.003
E55 Vitamin D deficiency
0.003 0.997 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.000 0.997 0.003
E50.9 Vitamin A deficiency, unspecified
0.003 0.997 0.000
E50.8 Other manifestations of vitamin A deficiency
0.003 0.997 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.003 0.997 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.003 0.997 0.000
E50.5 Vitamin A deficiency with night blindness
0.003 0.997 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.003 0.997 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.003 0.997 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.003 0.997 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.003 0.997 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.003 0.997 0.000
E51.9 Thiamine deficiency, unspecified
0.003 0.997 0.000
E51.8 Other manifestations of thiamine deficiency
0.003 0.997 0.000
E51.2 Wernicke's encephalopathy
0.003 0.997 0.000
E51.1 Beriberi
0.003 0.997 0.000
E63.9 Nutritional deficiency, unspecified
0.003 0.997 0.000
E63.8 Other specified nutritional deficiencies
0.003 0.997 0.000
E63.1 Imbalance of constituents of food intake
0.003 0.997 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.003 0.997 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.003 0.997 0.000
E64.8 Sequelae of other nutritional deficiencies
0.003 0.997 0.000
E64.3 Sequelae of rickets
0.003 0.997 0.000
E64.2 Sequelae of vitamin C deficiency
0.003 0.997 0.000
E64.1 Sequelae of vitamin A deficiency
0.003 0.997 0.000
E64.0 Sequelae of protein-energy malnutrition
0.003 0.997 0.000
H65.1 Other acute nonsuppurative otitis media
0.000 0.997 0.003
Z31.2 In vitro fertilisation
0.000 0.997 0.003
E61 Deficiency of other nutrient elements
0.003 0.997 0.000
M86.86 Other osteomyelitis (Lower leg)
0.003 0.997 0.000
M86.6 Other chronic osteomyelitis
0.003 0.997 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.003 0.997 0.000
S02.50 Fracture of tooth (closed)
0.003 0.997 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.000 0.997 0.003
C85.1 B-cell lymphoma, unspecified
0.000 0.997 0.003
Z31 Procreative management
0.000 0.997 0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.997 0.003
H65.2 Chronic serous otitis media
0.000 0.997 0.003
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.997 0.003
M86.96 Osteomyelitis, unspecified (Lower leg)
0.003 0.997 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.003 0.997 0.000
M86.3 Chronic multifocal osteomyelitis
0.003 0.997 0.000
M86.2 Subacute osteomyelitis
0.003 0.997 0.000
M86.1 Other acute osteomyelitis
0.003 0.997 0.000
M86.0 Acute haematogenous osteomyelitis
0.003 0.997 0.000
E53 Deficiency of other B group vitamins
0.003 0.997 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.997 0.003
Z31.8 Other procreative management
0.000 0.997 0.003
Z31.4 Procreative investigation and testing
0.000 0.997 0.003
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.003 0.997 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.003 0.997 0.000
E80.4 Gilbert's syndrome
0.003 0.997 0.000
H65.4 Other chronic nonsuppurative otitis media
0.000 0.997 0.003
M89.04 Algoneurodystrophy (Hand)
0.003 0.997 0.000
S82.20 Fracture of shaft of tibia (closed)
0.003 0.997 0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.002 0.997 0.000
E67.8 Other specified hyperalimentation
0.002 0.997 0.000
E67.3 Hypervitaminosis D
0.002 0.997 0.000
E67.2 Megavitamin-B6 syndrome
0.002 0.997 0.000
E67.1 Hypercarotenaemia
0.002 0.997 0.000
E67.0 Hypervitaminosis A
0.002 0.997 0.000
M86.89 Other osteomyelitis (Site unspecified)
0.002 0.997 0.000
M86.88 Other osteomyelitis (Other)
0.002 0.997 0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)
0.002 0.997 0.000
M86.84 Other osteomyelitis (Hand)
0.002 0.997 0.000
M86.83 Other osteomyelitis (Forearm)
0.002 0.997 0.000
M86.82 Other osteomyelitis (Upper arm)
0.002 0.997 0.000
M86.81 Other osteomyelitis (Shoulder region)
0.002 0.997 0.000
M86.80 Other osteomyelitis (Multiple sites)
0.002 0.997 0.000
M86.87 Other osteomyelitis (Ankle and foot)
0.002 0.997 0.000
E55.0 Rickets, active
0.002 0.997 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.002 0.997 0.000
E61.9 Deficiency of nutrient element, unspecified
0.002 0.998 0.000
E61.8 Deficiency of other specified nutrient elements
0.002 0.998 0.000
E61.7 Deficiency of multiple nutrient elements
0.002 0.998 0.000
E61.6 Vanadium deficiency
0.002 0.998 0.000
E61.5 Molybdenum deficiency
0.002 0.998 0.000
E61.4 Chromium deficiency
0.002 0.998 0.000
E61.3 Manganese deficiency
0.002 0.998 0.000
E61.0 Copper deficiency
0.002 0.998 0.000
L95.9 Vasculitis limited to skin, unspecified
0.000 0.998 0.002
M86.68 Other chronic osteomyelitis (Other)
0.002 0.998 0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.64 Other chronic osteomyelitis (Hand)
0.002 0.998 0.000
M86.63 Other chronic osteomyelitis (Forearm)
0.002 0.998 0.000
M86.62 Other chronic osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.61 Other chronic osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.60 Other chronic osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)
0.002 0.998 0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)
0.002 0.998 0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)
0.002 0.998 0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)
0.002 0.998 0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)
0.002 0.998 0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)
0.002 0.998 0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)
0.002 0.998 0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)
0.002 0.998 0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)
0.002 0.998 0.000
N99.2 Postprocedural adhesions of vagina
0.000 0.998 0.002
E65 Localised adiposity
0.002 0.998 0.000
G30 Alzheimer's disease
0.002 0.998 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.000 0.998 0.002
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.998 0.002
Z31.9 Procreative management, unspecified
0.000 0.998 0.002
Z31.6 General counselling and advice on procreation
0.000 0.998 0.002
Z31.5 Genetic counselling
0.000 0.998 0.002
Z31.3 Other assisted fertilisation methods
0.000 0.998 0.002
Z31.1 Artifical insemination
0.000 0.998 0.002
M86.66 Other chronic osteomyelitis (Lower leg)
0.002 0.998 0.000
J95.5 Postprocedural subglottic stenosis
0.000 0.998 0.002
J95.4 Mendelson's syndrome
0.000 0.998 0.002
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.998 0.002
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.998 0.002
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.998 0.002
N99.0 Postprocedural renal failure
0.000 0.998 0.002
E61.2 Magnesium deficiency
0.002 0.998 0.000
H65.0 Acute serous otitis media
0.000 0.998 0.002
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.08 Acute haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.04 Acute haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.19 Other acute osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.18 Other acute osteomyelitis (Other)
0.002 0.998 0.000
M86.17 Other acute osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.16 Other acute osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.14 Other acute osteomyelitis (Hand)
0.002 0.998 0.000
M86.13 Other acute osteomyelitis (Forearm)
0.002 0.998 0.000
M86.12 Other acute osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.11 Other acute osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.10 Other acute osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.29 Subacute osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.28 Subacute osteomyelitis (Other)
0.002 0.998 0.000
M86.27 Subacute osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.26 Subacute osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.24 Subacute osteomyelitis (Hand)
0.002 0.998 0.000
M86.23 Subacute osteomyelitis (Forearm)
0.002 0.998 0.000
M86.22 Subacute osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.21 Subacute osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.20 Subacute osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.38 Chronic multifocal osteomyelitis (Other)
0.002 0.998 0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.34 Chronic multifocal osteomyelitis (Hand)
0.002 0.998 0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)
0.002 0.998 0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)
0.002 0.998 0.000
G30.8 Other Alzheimer's disease
0.002 0.998 0.000
N99.5 Malfunction of external stoma of urinary tract
0.000 0.998 0.002
E53.1 Pyridoxine deficiency
0.002 0.998 0.000
E53.0 Riboflavin deficiency
0.002 0.998 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.000 0.998 0.002
W08.0 Home
0.000 0.998 0.002
I33.0 Acute and subacute infective endocarditis
0.002 0.998 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.000 0.998 0.002
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.998 0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.002 0.998 0.000
M23.3 Other meniscus derangements
0.002 0.998 0.000
H95.1 Other disorders following mastoidectomy
0.002 0.998 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.998 0.002
C56 Malignant neoplasm of ovary
0.000 0.998 0.002
G30.0 Alzheimer's disease with early onset
0.002 0.998 0.000
E53.9 Vitamin B deficiency, unspecified
0.002 0.998 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.998 0.002
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.002 0.998 0.000
M51.9 Intervertebral disk disorder, unspecified
0.000 0.998 0.002
E28.2 Polycystic ovarian syndrome
0.002 0.998 0.000
E28 Ovarian dysfunction
0.002 0.998 0.000
E28.3 Primary ovarian failure
0.002 0.998 0.000
L03.0 Cellulitis of finger and toe
0.000 0.998 0.002
D32.0 Cerebral meninges
0.000 0.998 0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.002 0.998 0.000
K70.4 Alcoholic hepatic failure
0.002 0.998 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.000 0.998 0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.000 0.998 0.002
M89.94 Disorder of bone, unspecified (Hand)
0.002 0.998 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.998 0.002
M89.9 Disorder of bone, unspecified
0.002 0.998 0.000
D68.2 Hereditary deficiency of other clotting factors
0.000 0.998 0.002
M89.0 Algoneurodystrophy
0.002 0.998 0.000
M23.37 Other meniscus derangements-Capsular lig
0.002 0.998 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.002 0.998 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.002 0.998 0.000
O62.2 Other uterine inertia
0.000 0.998 0.002
N99.1 Postprocedural urethral stricture
0.000 0.998 0.002
E16 Other disorders of pancreatic internal secretion
0.002 0.998 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.998 0.002
T20.2 Burn of second degree of head and neck
0.002 0.998 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.998 0.002
G30.1 Alzheimer's disease with late onset
0.002 0.998 0.000
M89 Other disorders of bone
0.002 0.998 0.000
E61.1 Iron deficiency
0.002 0.998 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.002 0.998 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.002 0.998 0.000
G35 Multiple sclerosis
0.002 0.998 0.000
E28.9 Ovarian dysfunction, unspecified
0.002 0.998 0.000
E28.8 Other ovarian dysfunction
0.002 0.998 0.000
E28.1 Androgen excess
0.002 0.998 0.000
E28.0 Oestrogen excess
0.002 0.998 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.002 0.998 0.000
E20-E35 Disorders of other endocrine glands
0.002 0.998 0.000
M25.76 Osteophyte (Lower leg)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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