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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12591531
log Bayes Factor = 5.81695
Chromosome 15   position 28,427,916  (GRCh37) Explore rs12591531 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H25 Senile cataract
1.000 0.000 0.000
H25-H28 Disorders of lens
1.000 0.000 0.000
H25.8 Other senile cataract
1.000 0.000 0.000
H25.1 Senile nuclear cataract
0.999 0.001 0.000
H26 Other cataract
0.999 0.001 0.000
H26.9 Cataract, unspecified
0.998 0.002 0.000
H40 Glaucoma
0.945 0.055 0.000
H40-H42 Glaucoma
0.937 0.063 0.000
H40.9 Glaucoma, unspecified
0.936 0.064 0.000
Chapter VII Diseases of the eye and adnexa
0.932 0.068 0.000
H26.8 Other specified cataract
0.930 0.070 0.000
H40.2 Primary angle-closure glaucoma
0.918 0.082 0.000
H25.9 Senile cataract, unspecified
0.881 0.119 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.870 0.130 0.000
H40.5 Glaucoma secondary to other eye disorders
0.812 0.188 0.000
H40.1 Primary open-angle glaucoma
0.804 0.196 0.000
M35 Other systemic involvement of connective tissue
0.790 0.210 0.000
M35.3 Polymyalgia rheumatica
0.786 0.214 0.000
H52 Disorders of refraction and accommodation
0.783 0.217 0.000
M20-M25 Other joint disorders
0.782 0.218 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.776 0.224 0.000
H26.2 Complicated cataract
0.773 0.227 0.000
H40.4 Glaucoma secondary to eye inflammation
0.769 0.231 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.767 0.233 0.000
M35.0 Sicca syndrome [Sjogren]
0.766 0.234 0.000
H26.0 Infantile, juvenile and presenile cataract
0.758 0.242 0.000
M05-M14 Inflammatory polyarthropathies
0.748 0.252 0.000
M34 Systemic sclerosis
0.743 0.257 0.000
M25 Other joint disorders, not elsewhere classified
0.731 0.269 0.000
H49 Paralytic strabismus
0.730 0.270 0.000
M06 Other rheumatoid arthritis
0.728 0.272 0.000
M15-M19 Arthrosis
0.727 0.273 0.000
M16 Coxarthrosis [arthrosis of hip]
0.726 0.274 0.000
M05 Seropositive rheumatoid arthritis
0.723 0.277 0.000
H52.3 Anisometropia and aniseikonia
0.718 0.282 0.000
H25.2 Senile cataract, morgagnian type
0.717 0.283 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.717 0.283 0.000
H26.3 Drug-induced cataract
0.716 0.284 0.000
M16.0 Primary coxarthrosis, bilateral
0.716 0.284 0.000
M06.9 Rheumatoid arthritis, unspecified
0.707 0.293 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.705 0.295 0.000
M25.7 Osteophyte
0.699 0.301 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.692 0.308 0.000
M16.1 Other primary coxarthrosis
0.691 0.309 0.000
M25.76 Osteophyte (Lower leg)
0.688 0.312 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.680 0.320 0.000
H27 Other disorders of lens
0.678 0.322 0.000
H40.6 Glaucoma secondary to drugs
0.677 0.322 0.000
H40.3 Glaucoma secondary to eye trauma
0.677 0.322 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
H42 Glaucoma in diseases classified elsewhere
0.672 0.328 0.000
H26.1 Traumatic cataract
0.668 0.331 0.000
H18 Other disorders of cornea
0.665 0.335 0.000
M34.9 Systemic sclerosis, unspecified
0.664 0.336 0.000
M80-M85 Disorders of bone density and structure
0.662 0.338 0.000
H50 Other strabismus
0.651 0.349 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.646 0.354 0.000
M25.8 Other specified joint disorders
0.644 0.356 0.000
H52.1 Myopia
0.640 0.360 0.000
M24 Other specific joint derangements
0.634 0.366 0.000
M91-M94 Chondropathies
0.628 0.372 0.000
H49.0 Third [oculomotor] nerve palsy
0.627 0.373 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.626 0.374 0.000
H40.0 Glaucoma suspect
0.626 0.374 0.000
M34.1 CR(E)ST syndrome
0.626 0.374 0.000
H51 Other disorders of binocular movement
0.624 0.376 0.000
M22 Disorders of patella
0.624 0.376 0.000
M35.8 Other specified systemic involvement of connective tissue
0.622 0.378 0.000
H15 Disorders of sclera
0.620 0.380 0.000
M35.2 Behcet's disease
0.619 0.381 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.612 0.388 0.000
M34.8 Other forms of systemic sclerosis
0.609 0.391 0.000
H20 Iridocyclitis
0.609 0.391 0.000
M25.78 Osteophyte (Other)
0.606 0.394 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.597 0.402 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.595 0.405 0.000
H17 Corneal scars and opacities
0.595 0.405 0.000
M89 Other disorders of bone
0.591 0.409 0.000
H40.8 Other glaucoma
0.574 0.426 0.000
M30 Polyarteritis nodosa and related conditions
0.573 0.427 0.000
H18.4 Corneal degeneration
0.571 0.429 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.571 0.429 0.000
M06.0 Seronegative rheumatoid arthritis
0.569 0.431 0.000
M14 Arthropathies in other diseases classified elsewhere
0.567 0.433 0.000
M50-M54 Other dorsopathies
0.567 0.433 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.567 0.433 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.566 0.433 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.566 0.433 0.000
M35.5 Multifocal fibrosclerosis
0.566 0.433 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.566 0.433 0.000
H18.9 Disorder of cornea, unspecified
0.565 0.435 0.000
M00-M03 Infectious arthropathies
0.565 0.435 0.000
M16.7 Other secondary coxarthrosis
0.562 0.438 0.000
H52.7 Disorder of refraction, unspecified
0.561 0.439 0.000
H52.6 Other disorders of refraction
0.561 0.439 0.000
H52.5 Disorders of accommodation
0.561 0.439 0.000
H52.4 Presbyopia
0.561 0.439 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.561 0.439 0.000
M33 Dermatopolymyositis
0.558 0.442 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.557 0.443 0.000
M32 Systemic lupus erythematosus
0.557 0.443 0.000
M85 Other disorders of bone density and structure
0.557 0.443 0.000
M25.74 Osteophyte (Hand)
0.555 0.444 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.555 0.445 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.555 0.445 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.554 0.445 0.000
M84 Disorders of continuity of bone
0.552 0.448 0.000
M06.3 Rheumatoid nodule
0.552 0.448 0.000
M60-M63 Disorders of muscles
0.549 0.451 0.000
M86 Osteomyelitis
0.546 0.453 0.000
M54 Dorsalgia
0.543 0.457 0.000
M25.9 Joint disorder, unspecified
0.542 0.458 0.000
M94 Other disorders of cartilage
0.542 0.458 0.000
H49.1 Fourth [trochlear] nerve palsy
0.538 0.462 0.000
M12 Other specific arthropathies
0.537 0.463 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.537 0.463 0.000
M08 Juvenile arthritis
0.537 0.463 0.000
M24.2 Disorder of ligament
0.535 0.465 0.000
M22.8 Other disorders of patella
0.533 0.467 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.533 0.467 0.000
M34.0 Progressive systemic sclerosis
0.533 0.467 0.000
M40-M43 Deforming dorsopathies
0.532 0.468 0.000
M15 Polyarthrosis
0.532 0.468 0.000
M35.1 Other overlap syndromes
0.530 0.469 0.000
H50.0 Convergent concomitant strabismus
0.529 0.471 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.529 0.471 0.000
M88 Paget's disease of bone [osteitis deformans]
0.529 0.471 0.000
M82 Osteoporosis in diseases classified elsewhere
0.529 0.471 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.527 0.473 0.000
M54.3 Sciatica
0.526 0.474 0.000
M25.2 Flail joint
0.524 0.476 0.000
M25.1 Fistula of joint
0.524 0.476 0.000
H49.9 Paralytic strabismus, unspecified
0.523 0.477 0.000
H49.8 Other paralytic strabismus
0.523 0.477 0.000
H49.4 Progressive external ophthalmoplegia
0.523 0.477 0.000
H49.3 Total (external) ophthalmoplegia
0.523 0.477 0.000
M06.8 Other specified rheumatoid arthritis
0.522 0.478 0.000
M06.2 Rheumatoid bursitis
0.522 0.478 0.000
M06.1 Adult-onset Still's disease
0.522 0.478 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.520 0.480 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.520 0.480 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.520 0.480 0.000
M05.8 Other seropositive rheumatoid arthritis
0.518 0.481 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.518 0.481 0.000
M05.2 Rheumatoid vasculitis
0.518 0.481 0.000
M05.1 Rheumatoid lung disease
0.518 0.481 0.000
M05.0 Felty's syndrome
0.518 0.481 0.000
H52.2 Astigmatism
0.518 0.481 0.000
M16.3 Other dysplastic coxarthrosis
0.518 0.482 0.000
H18.5 Hereditary corneal dystrophies
0.517 0.483 0.000
H20.0 Acute and subacute iridocyclitis
0.516 0.484 0.000
M06.4 Inflammatory polyarthropathy
0.516 0.484 0.000
H28.8 Other disorders of lens in diseases classified elsewhere
0.514 0.486 0.000
H28.2 Cataract in other diseases classified elsewhere
0.514 0.486 0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.514 0.486 0.000
H28.0 Diabetic cataract
0.514 0.486 0.000
H49.2 Sixth [abducent] nerve palsy
0.512 0.488 0.000
M16.5 Other posttraumatic coxarthrosis
0.509 0.491 0.000
H15.0 Scleritis
0.509 0.491 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.508 0.492 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.507 0.493 0.000
H52.0 Hypermetropia
0.506 0.493 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.506 0.494 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.506 0.494 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.506 0.494 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.506 0.494 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.506 0.494 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.506 0.494 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.506 0.494 0.000
M17 Gonarthrosis [arthrosis of knee]
0.505 0.495 0.000
M25.84 Other specified joint disorders (Hand)
0.502 0.498 0.000
M80 Osteoporosis with pathological fracture
0.502 0.498 0.000
M25.79 Osteophyte (Site unspecified)
0.501 0.499 0.000
M25.73 Osteophyte (Forearm)
0.501 0.499 0.000
M25.70 Osteophyte (Multiple sites)
0.501 0.499 0.000
H18.2 Other corneal oedema
0.497 0.503 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.494 0.506 0.000
M54.39 Sciatica (Site unspecified)
0.493 0.507 0.000
M24.5 Contracture of joint
0.492 0.508 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.491 0.509 0.000
H50.5 Heterophoria
0.490 0.509 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.488 0.512 0.000
M89.8 Other specified disorders of bone
0.488 0.512 0.000
H43-H45 Disorders of vitreous body and globe
0.487 0.512 0.000
H27.9 Disorder of lens, unspecified
0.486 0.514 0.000
H27.0 Aphakia
0.485 0.515 0.000
M89.0 Algoneurodystrophy
0.484 0.516 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.483 0.517 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.482 0.518 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.482 0.518 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.482 0.518 0.000
H27.8 Other specified disorders of lens
0.480 0.520 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.479 0.521 0.000
H18.1 Bullous keratopathy
0.479 0.521 0.000
M22.4 Chondromalacia patellae
0.478 0.521 0.000
M94.2 Chondromalacia
0.478 0.522 0.000
M25.3 Other instability of joint
0.478 0.522 0.000
M31 Other necrotising vasculopathies
0.477 0.522 0.000
H18.7 Other corneal deformities
0.477 0.523 0.000
H18.3 Changes in corneal membranes
0.477 0.523 0.000
H18.0 Corneal pigmentations and deposits
0.477 0.523 0.000
M54.5 Low back pain
0.477 0.523 0.000
M83 Adult osteomalacia
0.474 0.525 0.000
M85.8 Other specified disorders of bone density and structure
0.474 0.526 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.473 0.527 0.000
M24.7 Protrusio acetabuli
0.472 0.528 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.469 0.530 0.000
H18.6 Keratoconus
0.468 0.532 0.000
H50.8 Other specified strabismus
0.467 0.533 0.000
H50.6 Mechanical strabismus
0.467 0.533 0.000
H50.4 Other and unspecified heterotropia
0.467 0.533 0.000
H50.3 Intermittent heterotropia
0.467 0.533 0.000
M17.1 Other primary gonarthrosis
0.466 0.534 0.000
M11 Other crystal arthropathies
0.463 0.536 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.463 0.537 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.463 0.537 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.463 0.537 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.463 0.537 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.463 0.537 0.000
M24.24 Disorder of ligament (Hand)
0.463 0.537 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.462 0.538 0.000
M25.88 Other specified joint disorders (Other)
0.462 0.538 0.000
M25.83 Other specified joint disorders (Forearm)
0.462 0.538 0.000
M25.82 Other specified joint disorders (Upper arm)
0.462 0.538 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.462 0.538 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.462 0.538 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.462 0.538 0.000
M90 Osteopathies in diseases classified elsewhere
0.459 0.541 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.459 0.541 0.000
M25.0 Haemarthrosis
0.459 0.541 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.459 0.541 0.000
M24.0 Loose body in joint
0.459 0.541 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.458 0.542 0.000
H27.1 Dislocation of lens
0.456 0.544 0.000
M24.9 Joint derangement, unspecified
0.454 0.545 0.000
M24.6 Ankylosis of joint
0.454 0.545 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.454 0.546 0.000
H17.8 Other corneal scars and opacities
0.454 0.546 0.000
M86.9 Osteomyelitis, unspecified
0.453 0.547 0.000
H50.2 Vertical strabismus
0.453 0.547 0.000
M92 Other juvenile osteochondrosis
0.451 0.549 0.000
M22.2 Patellofemoral disorders
0.448 0.552 0.000
H51.9 Disorder of binocular movement, unspecified
0.447 0.552 0.000
H51.8 Other specified disorders of binocular movement
0.447 0.552 0.000
H51.2 Internuclear ophthalmoplegia
0.447 0.552 0.000
H51.1 Convergence insufficiency and excess
0.447 0.552 0.000
H51.0 Palsy of conjugate gaze
0.447 0.552 0.000
M22.1 Recurrent subluxation of patella
0.447 0.552 0.000
M22.9 Disorder of patella, unspecified
0.447 0.552 0.000
M22.0 Recurrent dislocation of patella
0.447 0.552 0.000
H15.9 Disorder of sclera, unspecified
0.445 0.555 0.000
H15.8 Other disorders of sclera
0.445 0.555 0.000
H15.1 Episcleritis
0.445 0.555 0.000
H50.1 Divergent concomitant strabismus
0.445 0.555 0.000
M54.59 Low back pain (Site unspecified)
0.444 0.556 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.443 0.557 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.442 0.558 0.000
M89.5 Osteolysis
0.442 0.558 0.000
M07 Psoriatic and enteropathic arthropathies
0.440 0.560 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.440 0.560 0.000
H17.9 Corneal scar and opacity, unspecified
0.439 0.561 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.439 0.561 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.437 0.562 0.000
M14.6 Neuropathic arthropathy
0.437 0.563 0.000
H20.2 Lens-induced iridocyclitis
0.436 0.563 0.000
H20.1 Chronic iridocyclitis
0.436 0.563 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.436 0.564 0.000
M82.1 Osteoporosis in endocrine disorders
0.433 0.567 0.000
M17.3 Other posttraumatic gonarthrosis
0.433 0.567 0.000
M94.26 Chondromalacia (Lower leg)
0.433 0.567 0.000
M87 Osteonecrosis
0.432 0.567 0.000
M65-M68 Disorders of synovium and tendon
0.431 0.569 0.000
M54.37 Sciatica (Lumbosacral region)
0.430 0.570 0.000
H16 Keratitis
0.429 0.571 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.428 0.571 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.428 0.571 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.428 0.571 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.428 0.571 0.000
M53 Other dorsopathies, not elsewhere classified
0.428 0.572 0.000
M02 Reactive arthropathies
0.427 0.573 0.000
M99 Biomechanical lesions, not elsewhere classified
0.427 0.573 0.000
M25.72 Osteophyte (Upper arm)
0.427 0.573 0.000
M89.9 Disorder of bone, unspecified
0.427 0.573 0.000
H17.1 Other central corneal opacity
0.426 0.573 0.000
H17.0 Adherent leukoma
0.426 0.573 0.000
M85.0 Fibrous dysplasia (monostotic)
0.426 0.573 0.000
M84.8 Other disorders of continuity of bone
0.426 0.574 0.000
H50.9 Strabismus, unspecified
0.425 0.575 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.424 0.576 0.000
M89.6 Osteopathy after poliomyelitis
0.424 0.576 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.424 0.576 0.000
M89.2 Other disorders of bone development and growth
0.424 0.576 0.000
M89.1 Epiphyseal arrest
0.424 0.576 0.000
M88.9 Paget's disease of bone, unspecified
0.423 0.577 0.000
H20.8 Other iridocyclitis
0.423 0.577 0.000
M35.7 Hypermobility syndrome
0.420 0.580 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.420 0.580 0.000
H10-H13 Disorders of conjunctiva
0.415 0.585 0.000
M84.0 Malunion of fracture
0.414 0.586 0.000
M89.3 Hypertrophy of bone
0.412 0.588 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.411 0.589 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.411 0.589 0.000
M30.2 Juvenile polyarteritis
0.411 0.589 0.000
M30.0 Polyarteritis nodosa
0.411 0.589 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.411 0.589 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.411 0.589 0.000
M54.1 Radiculopathy
0.409 0.591 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.408 0.592 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.408 0.592 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.408 0.592 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.408 0.592 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.408 0.592 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.408 0.592 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.408 0.592 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.408 0.592 0.000
M21 Other acquired deformities of limbs
0.408 0.592 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.407 0.593 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.407 0.593 0.000
M14.4 Arthropathy in amyloidosis
0.407 0.593 0.000
M14.3 Lipoid dermatoarthritis
0.407 0.593 0.000
M14.2 Diabetic arthropathy
0.407 0.593 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.407 0.593 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.407 0.593 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.406 0.594 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.406 0.594 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.405 0.595 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.405 0.595 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.402 0.598 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.402 0.598 0.000
M36.3 Arthropathy in other blood disorders
0.402 0.598 0.000
M36.2 Haemophilic arthropathy
0.402 0.598 0.000
M36.1 Arthropathy in neoplastic disease
0.402 0.598 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.402 0.598 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.402 0.598 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.402 0.598 0.000
H20.9 Iridocyclitis, unspecified
0.401 0.598 0.000
M54.6 Pain in thoracic spine
0.400 0.600 0.000
M33.9 Dermatopolymyositis, unspecified
0.400 0.600 0.000
M33.1 Other dermatomyositis
0.400 0.600 0.000
M33.0 Juvenile dermatomyositis
0.400 0.600 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.399 0.601 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.399 0.601 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.399 0.601 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.399 0.601 0.000
M32.8 Other forms of systemic lupus erythematosus
0.399 0.601 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.399 0.601 0.000
M85.9 Disorder of bone density and structure, unspecified
0.399 0.601 0.000
M85.5 Aneurysmal bone cyst
0.399 0.601 0.000
M85.4 Solitary bone cyst
0.399 0.601 0.000
M85.3 Osteitis condensans
0.399 0.601 0.000
M85.2 Hyperostosis of skull
0.399 0.601 0.000
M85.1 Skeletal fluorosis
0.399 0.601 0.000
M00 Pyogenic arthritis
0.397 0.603 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.397 0.603 0.000
M33.2 Polymyositis
0.397 0.603 0.000
M84.9 Disorder of continuity of bone, unspecified
0.396 0.604 0.000
M84.4 Pathological fracture, not elsewhere classified
0.396 0.604 0.000
M84.3 Stress fracture, not elsewhere classified
0.396 0.604 0.000
M84.2 Delayed union of fracture
0.396 0.604 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.396 0.604 0.000
M06.38 Rheumatoid nodule (Other)
0.396 0.604 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.396 0.604 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.396 0.604 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.396 0.604 0.000
M06.33 Rheumatoid nodule (Forearm)
0.396 0.604 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.396 0.604 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.396 0.604 0.000
M54.8 Other dorsalgia
0.396 0.604 0.000
M40 Kyphosis and lordosis
0.396 0.604 0.000
M25.71 Osteophyte (Shoulder region)
0.395 0.605 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.395 0.605 0.000
M25.86 Other specified joint disorders (Lower leg)
0.394 0.606 0.000
M62 Other disorders of muscle
0.394 0.606 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.393 0.606 0.000
M61 Calcification and ossification of muscle
0.393 0.606 0.000
H21 Other disorders of iris and ciliary body
0.393 0.607 0.000
M15.1 Heberden's nodes (with arthropathy)
0.392 0.608 0.000
M86.8 Other osteomyelitis
0.392 0.608 0.000
M86.6 Other chronic osteomyelitis
0.392 0.608 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.392 0.608 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.392 0.608 0.000
M86.3 Chronic multifocal osteomyelitis
0.392 0.608 0.000
M86.2 Subacute osteomyelitis
0.392 0.608 0.000
M86.1 Other acute osteomyelitis
0.392 0.608 0.000
M86.0 Acute haematogenous osteomyelitis
0.392 0.608 0.000
M60 Myositis
0.392 0.608 0.000
M24.56 Contracture of joint (Lower leg)
0.391 0.609 0.000
M94.8 Other specified disorders of cartilage
0.390 0.610 0.000
M54.0 Panniculitis affecting regions of neck and back
0.390 0.610 0.000
M43 Other deforming dorsopathies
0.389 0.610 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.389 0.610 0.000
M94.9 Disorder of cartilage, unspecified
0.389 0.611 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.389 0.611 0.000
M10 Gout
0.389 0.611 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.388 0.611 0.000
M25.98 Joint disorder, unspecified (Other)
0.388 0.611 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.388 0.611 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.388 0.611 0.000
M25.94 Joint disorder, unspecified (Hand)
0.388 0.611 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.388 0.611 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.388 0.611 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.388 0.611 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.388 0.611 0.000
M94.3 Chondrolysis
0.388 0.612 0.000
M94.1 Relapsing polychondritis
0.388 0.612 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.388 0.612 0.000
M89.04 Algoneurodystrophy (Hand)
0.386 0.614 0.000
M54.36 Sciatica (Lumbar region)
0.385 0.615 0.000
M08.9 Juvenile arthritis, unspecified
0.385 0.615 0.000
M08.8 Other juvenile arthritis
0.385 0.615 0.000
M08.4 Pauciarticular juvenile arthritis
0.385 0.615 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.385 0.615 0.000
M08.2 Juvenile arthritis with systemic onset
0.385 0.615 0.000
M08.1 Juvenile ankylosing spondylitis
0.385 0.615 0.000
M08.0 Juvenile rheumatoid arthritis
0.385 0.615 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.385 0.615 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.385 0.615 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.385 0.615 0.000
M09.0 Juvenile arthritis in psoriasis
0.385 0.615 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.385 0.615 0.000
M12.5 Traumatic arthropathy
0.385 0.615 0.000
M12.4 Intermittent hydrarthrosis
0.385 0.615 0.000
M12.3 Palindromic rheumatism
0.385 0.615 0.000
M12.2 Villonodular synovitis (pigmented)
0.385 0.615 0.000
M12.1 Kaschin-Beck disease
0.385 0.615 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.385 0.615 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.384 0.616 0.000
M24.29 Disorder of ligament (Site unspecified)
0.384 0.616 0.000
M24.28 Disorder of ligament (Other)
0.384 0.616 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.384 0.616 0.000
M24.22 Disorder of ligament (Upper arm)
0.384 0.616 0.000
M24.21 Disorder of ligament (Shoulder region)
0.384 0.616 0.000
M24.20 Disorder of ligament (Multiple sites)
0.384 0.616 0.000
M24.1 Other articular cartilage disorders
0.383 0.617 0.000
M42 Spinal osteochondrosis
0.382 0.618 0.000
M85.6 Other cyst of bone
0.382 0.618 0.000
M15.9 Polyarthrosis, unspecified
0.381 0.618 0.000
M15.0 Primary generalised (osteo)arthrosis
0.381 0.618 0.000
M15.8 Other polyarthrosis
0.381 0.618 0.000
M15.4 Erosive (osteo)arthrosis
0.381 0.618 0.000
M15.3 Secondary multiple arthrosis
0.381 0.618 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.381 0.618 0.000
M93 Other osteochondropathies
0.380 0.619 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.380 0.620 0.000
M88.8 Paget's disease of other bones
0.379 0.620 0.000
M88.0 Paget's disease of skull
0.379 0.620 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.379 0.621 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.379 0.621 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.379 0.621 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.379 0.621 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.379 0.621 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.379 0.621 0.000
M91.2 Coxa plana
0.378 0.622 0.000
M54.4 Lumbago with sciatica
0.378 0.622 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.378 0.622 0.000
H46 Optic neuritis
0.378 0.622 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.378 0.622 0.000
M54.35 Sciatica (Thoracolumbar region)
0.377 0.622 0.000
M54.34 Sciatica-Thoracic
0.377 0.622 0.000
M54.33 Sciatica-Cervicothoracic
0.377 0.622 0.000
M54.32 Sciatica-Cervical
0.377 0.622 0.000
M54.31 Sciatica-Occipit-atl-axl
0.377 0.622 0.000
M54.30 Sciatica (Multiple sites in spine)
0.377 0.622 0.000
M25.19 Fistula of joint (Site unspecified)
0.376 0.624 0.000
M25.18 Fistula of joint (Other)
0.376 0.624 0.000
M25.17 Fistula of joint (Ankle and foot)
0.376 0.624 0.000
M25.16 Fistula of joint (Lower leg)
0.376 0.624 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.376 0.624 0.000
M25.14 Fistula of joint (Hand)
0.376 0.624 0.000
M25.13 Fistula of joint (Forearm)
0.376 0.624 0.000
M25.12 Fistula of joint (Upper arm)
0.376 0.624 0.000
M25.11 Fistula of joint (Shoulder region)
0.376 0.624 0.000
M25.10 Fistula of joint (Multiple sites)
0.376 0.624 0.000
M25.29 Flail joint (Site unspecified)
0.376 0.624 0.000
M25.28 Flail joint (Other)
0.376 0.624 0.000
M25.27 Flail joint (Ankle and foot)
0.376 0.624 0.000
M25.26 Flail joint (Lower leg)
0.376 0.624 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.376 0.624 0.000
M25.24 Flail joint (Hand)
0.376 0.624 0.000
M25.23 Flail joint (Forearm)
0.376 0.624 0.000
M25.22 Flail joint (Upper arm)
0.376 0.624 0.000
M25.21 Flail joint (Shoulder region)
0.376 0.624 0.000
M25.20 Flail joint (Multiple sites)
0.376 0.624 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.376 0.624 0.000
M24.26 Disorder of ligament (Lower leg)
0.376 0.624 0.000
H25.0 Senile incipient cataract
0.375 0.625 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.374 0.625 0.000
M06.18 Adult-onset Still's disease (Other)
0.374 0.625 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.374 0.625 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.374 0.625 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.374 0.625 0.000
M06.14 Adult-onset Still's disease (Hand)
0.374 0.625 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.374 0.625 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.374 0.625 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.374 0.625 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.374 0.625 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.374 0.625 0.000
M06.28 Rheumatoid bursitis (Other)
0.374 0.625 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.374 0.625 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.374 0.625 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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