TreeWAS – Variant ID: rs12598357

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	0.987	0.013	0.000
E66 Obesity	0.511	0.489	0.000
E66.8 Other obesity	0.426	0.574	0.000
E66.1 Drug-induced obesity	0.366	0.634	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.354	0.646	0.000
E66.0 Obesity due to excess calories	0.300	0.700	0.000
E65-E68 Obesity and other hyperalimentation	0.144	0.856	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.126	0.874	0.000
E67 Other hyperalimentation	0.103	0.897	0.000
E68 Sequelae of hyperalimentation	0.103	0.897	0.000
E67.8 Other specified hyperalimentation	0.074	0.926	0.000
E67.3 Hypervitaminosis D	0.074	0.926	0.000
E67.2 Megavitamin-B6 syndrome	0.074	0.926	0.000
E67.1 Hypercarotenaemia	0.074	0.926	0.000
E67.0 Hypervitaminosis A	0.074	0.926	0.000
E65 Localised adiposity	0.069	0.931	0.000
I83 Varicose veins of lower extremities	0.050	0.950	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.043	0.957	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.037	0.963	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.019	0.981	0.000
J18.9 Pneumonia, unspecified	0.018	0.982	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.984	0.016
R60.9 Oedema, unspecified	0.016	0.984	0.000
R60.0 Localised oedema	0.016	0.984	0.000
J18 Pneumonia, organism unspecified	0.015	0.985	0.000
J17 Pneumonia in diseases classified elsewhere	0.015	0.985	0.000
J09-J18 Influenza and pneumonia	0.015	0.985	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.014	0.986	0.000
J33.0 Polyp of nasal cavity	0.014	0.986	0.000
J17.3 Pneumonia in parasitic diseases	0.014	0.986	0.000
R60 Oedema, not elsewhere classified	0.014	0.986	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.013	0.987	0.000
L57.0 Actinic keratosis	0.013	0.987	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.013	0.987	0.000
J15.1 Pneumonia due to Pseudomonas	0.013	0.987	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.012	0.988	0.000
J15.5 Pneumonia due to Escherichia coli	0.012	0.988	0.000
J11 Influenza, virus not identified	0.012	0.988	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.012	0.988	0.000
J18.2 Hypostatic pneumonia, unspecified	0.012	0.988	0.000
J17.2 Pneumonia in mycoses	0.012	0.988	0.000
J18.0 Bronchopneumonia, unspecified	0.012	0.988	0.000
J15.9 Bacterial pneumonia, unspecified	0.012	0.988	0.000
J18.8 Other pneumonia, organism unspecified	0.011	0.988	0.000
J09 Influenza due to certain identified influenza virus	0.011	0.989	0.000
J15.2 Pneumonia due to staphylococcus	0.011	0.989	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.011	0.989	0.000
N42.9 Disorder of prostate, unspecified	0.011	0.989	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.011	0.989	0.000
J15.3 Pneumonia due to streptococcus, group B	0.010	0.990	0.000
J11.8 Influenza with other manifestations, virus not identified	0.010	0.990	0.000
J11.0 Influenza with pneumonia, virus not identified	0.010	0.990	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.010	0.990	0.000
J12 Viral pneumonia, not elsewhere classified	0.010	0.990	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.010	0.990	0.000
R60.1 Generalised oedema	0.010	0.990	0.000
J15.8 Other bacterial pneumonia	0.009	0.991	0.000
J14 Pneumonia due to Haemophilus influenzae	0.009	0.991	0.000
J10 Influenza due to identified influenza virus	0.009	0.991	0.000
E10.3 With ophthalmic complications	0.000	0.991	0.009
J15.4 Pneumonia due to other streptococci	0.009	0.991	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.992	0.008
Z93.5 Cystostomy status	0.008	0.992	0.000
N42.8 Other specified disorders of prostate	0.008	0.992	0.000
J33 Nasal polyp	0.008	0.992	0.000
N42 Other disorders of prostate	0.008	0.992	0.000
J33.9 Nasal polyp, unspecified	0.008	0.992	0.000
J12.1 Respiratory syncytial virus pneumonia	0.008	0.992	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.008	0.992	0.000
J12.8 Other viral pneumonia	0.007	0.993	0.000
J12.3 Human metapneumovirus pneumonia	0.007	0.993	0.000
J12.0 Adenoviral pneumonia	0.007	0.993	0.000
J16.0 Chlamydial pneumonia	0.007	0.993	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.007	0.993	0.000
G60.0 Hereditary motor and sensory neuropathy	0.007	0.993	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.007	0.993	0.000
D04.7 Skin of lower limb, including hip	0.007	0.993	0.000
J12.9 Viral pneumonia, unspecified	0.007	0.993	0.000
G31.2 Degeneration of nervous system due to alcohol	0.007	0.993	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.007	0.993	0.000
J12.2 Parainfluenza virus pneumonia	0.006	0.993	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.006	0.993	0.000
N42.2 Atrophy of prostate	0.007	0.993	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.006	0.994	0.000
N42.3 Dysplasia of prostate	0.006	0.994	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.006	0.994	0.000
J43.9 Emphysema, unspecified	0.006	0.994	0.000
K91.3 Postoperative intestinal obstruction	0.006	0.994	0.000
L43.9 Lichen planus, unspecified	0.000	0.994	0.006
G31.1 Senile degeneration of brain, not elsewhere classified	0.005	0.995	0.000
J33.1 Polypoid sinus degeneration	0.005	0.995	0.000
C78.2 Secondary malignant neoplasm of pleura	0.005	0.995	0.000
N42.0 Calculus of prostate	0.005	0.995	0.000
C56 Malignant neoplasm of ovary	0.005	0.995	0.000
J33.8 Other polyp of sinus	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.005	0.995	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.005	0.995	0.000
F60.9 Personality disorder, unspecified	0.000	0.995	0.005
N42.1 Congestion and haemorrhage of prostate	0.005	0.995	0.000
G31.8 Other specified degenerative diseases of nervous system	0.005	0.995	0.000
K11.2 Sialoadenitis	0.005	0.995	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.005	0.995	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.005	0.995	0.000
F60 Specific personality disorders	0.000	0.995	0.005
I49.0 Ventricular fibrillation and flutter	0.000	0.995	0.005
H83.0 Labyrinthitis	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.000	0.996	0.004
B80 Enterobiasis	0.000	0.996	0.004
G31.0 Circumscribed brain atrophy	0.004	0.996	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.996	0.004
R22.3 Localised swelling, mass and lump, upper limb	0.004	0.996	0.000
R22.2 Localised swelling, mass and lump, trunk	0.004	0.996	0.000
I81 Portal vein thrombosis	0.004	0.996	0.000
R23 Other skin changes	0.004	0.996	0.000
F60.5 Anankastic personality disorder	0.000	0.996	0.004
I87 Other disorders of veins	0.004	0.996	0.000
R23.0 Cyanosis	0.004	0.996	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.004	0.996	0.000
R23.3 Spontaneous ecchymoses	0.004	0.996	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.996	0.004
E16 Other disorders of pancreatic internal secretion	0.000	0.996	0.003
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
J43 Emphysema	0.004	0.996	0.000
F60.7 Dependent personality disorder	0.000	0.996	0.004
I87.1 Compression of vein	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
F60.4 Histrionic personality disorder	0.000	0.996	0.004
F60.2 Dissocial personality disorder	0.000	0.996	0.004
F60.1 Schizoid personality disorder	0.000	0.996	0.004
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
D38.1 Trachea, bronchus and lung	0.004	0.996	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.004	0.996	0.000
C52 Malignant neoplasm of vagina	0.004	0.996	0.000
F60.8 Other specific personality disorders	0.000	0.996	0.003
J43.2 Centrilobular emphysema	0.004	0.996	0.000
R22.0 Localised swelling, mass and lump, head	0.004	0.996	0.000
G60 Hereditary and idiopathic neuropathy	0.004	0.996	0.000
C51-C58 Malignant neoplasms of female genital organs	0.004	0.996	0.000
Q12.0 Congenital cataract	0.003	0.997	0.000
R23.1 Pallor	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
J43.8 Other emphysema	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.003	0.997	0.000
C53 Malignant neoplasm of cervix uteri	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
I85 Oesophageal varices	0.003	0.997	0.000
C54.9 Corpus uteri, unspecified	0.003	0.997	0.000
A46 Erysipelas	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
G45.4 Transient global amnesia	0.000	0.997	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
L43 Lichen planus	0.000	0.997	0.003
Q12 Congenital lens malformations	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.997	0.003
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.997	0.003
E16.4 Abnormal secretion of gastrin	0.000	0.997	0.003
E16.3 Increased secretion of glucagon	0.000	0.997	0.003
C54 Malignant neoplasm of corpus uteri	0.003	0.997	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
J43.1 Panlobular emphysema	0.003	0.997	0.000
J43.0 MacLeod's syndrome	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
I88 Nonspecific lymphadenitis	0.003	0.997	0.000
H83.8 Other specified diseases of inner ear	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
H83 Other diseases of inner ear	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
E16.1 Other hypoglycaemia	0.000	0.997	0.002
A39 Meningococcal infection	0.003	0.997	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
A39.4 Meningococcaemia, unspecified	0.003	0.997	0.000
G60.3 Idiopathic progressive neuropathy	0.003	0.997	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.003	0.997	0.000
G60.1 Refsum's disease	0.003	0.997	0.000
A48 Other bacterial diseases, not elsewhere classified	0.003	0.997	0.000
C58 Malignant neoplasm of placenta	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
C51 Malignant neoplasm of vulva	0.003	0.997	0.000
Z58.1 Exposure to air pollution	0.003	0.997	0.000
B99 Other and unspecified infectious diseases	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
L43.8 Other lichen planus	0.000	0.997	0.003
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
R53 Malaise and fatigue	0.003	0.997	0.000
A30-A49 Other bacterial diseases	0.003	0.997	0.000
A48.1 Legionnaires' disease	0.003	0.997	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.003	0.997	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.003	0.997	0.000
C53.8 Overlapping lesion of cervix uteri	0.002	0.997	0.000
C53.1 Exocervix	0.002	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.997	0.000
Q64.0 Epispadias	0.002	0.997	0.000
B02.3 Zoster ocular disease	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
N25 Disorders resulting from impaired renal tubular function	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
A48.8 Other specified bacterial diseases	0.003	0.997	0.000
B59 Pneumocystosis	0.003	0.997	0.000
B65-B83 Helminthiases	0.001	0.997	0.002
A39.0 Meningococcal meningitis	0.003	0.997	0.000
Q05 Spina bifida	0.002	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.997	0.002
I88.8 Other nonspecific lymphadenitis	0.002	0.997	0.000
J18.1 Lobar pneumonia, unspecified	0.003	0.997	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.997	0.000
Q84 Other congenital malformations of integument	0.002	0.997	0.000
Q81 Epidermolysis bullosa	0.002	0.997	0.000
Q80 Congenital ichthyosis	0.002	0.997	0.000
R23.2 Flushing	0.002	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
H83.2 Labyrinthine dysfunction	0.002	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.997	0.000
L43.3 Subacute (active) lichen planus	0.000	0.997	0.002
L43.2 Lichenoid drug reaction	0.000	0.997	0.002
L43.1 Bullous lichen planus	0.000	0.997	0.002
L43.0 Hypertrophic lichen planus	0.000	0.997	0.002
Q12.9 Congenital lens malformation, unspecified	0.002	0.997	0.000
Q12.8 Other congenital lens malformations	0.002	0.997	0.000
Q12.4 Spherophakia	0.002	0.997	0.000
Q12.3 Congenital aphakia	0.002	0.997	0.000
Q12.2 Coloboma of lens	0.002	0.997	0.000
Q12.1 Congenital displaced lens	0.002	0.997	0.000
G30-G32 Other degenerative diseases of the nervous system	0.003	0.997	0.000
C54.8 Overlapping lesion of corpus uteri	0.002	0.997	0.000
C54.3 Fundus uteri	0.002	0.997	0.000
C54.2 Myometrium	0.002	0.997	0.000
C54.0 Isthmus uteri	0.002	0.997	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.997	0.003
L57.3 Poikiloderma of Civatte	0.002	0.997	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.997	0.000
L57.1 Actinic reticuloid	0.002	0.997	0.000
Q05.9 Spina bifida, unspecified	0.002	0.997	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
A40 Streptococcal septicaemia	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
A40.2 Septicaemia due to streptococcus, group D	0.002	0.998	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
K59.1 Functional diarrhoea	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
C53.0 Endocervix	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
C51.0 Labium majus	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.998	0.001
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
A39.9 Meningococcal infection, unspecified	0.002	0.998	0.000
A39.8 Other meningococcal infections	0.002	0.998	0.000
A39.5 Meningococcal heart disease	0.002	0.998	0.000
A39.3 Chronic meningococcaemia	0.002	0.998	0.000
A39.2 Acute meningococcaemia	0.002	0.998	0.000
A39.1 Waterhouse-Friderichsen syndrome	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
N25-N29 Other disorders of kidney and ureter	0.002	0.998	0.000
A48.4 Brazilian purpuric fever	0.002	0.998	0.000
A48.3 Toxic shock syndrome	0.002	0.998	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.002	0.998	0.000
A48.0 Gas gangrene	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
C51.8 Overlapping lesion of vulva	0.002	0.998	0.000
C51.2 Clitoris	0.002	0.998	0.000
C51.1 Labium minus	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.002	0.998	0.000
A40.8 Other streptococcal septicaemia	0.002	0.998	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.002	0.998	0.000
K11 Diseases of salivary glands	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
N25.1 Nephrogenic diabetes insipidus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
A44 Bartonellosis	0.002	0.998	0.000
A43 Nocardiosis	0.002	0.998	0.000
A42 Actinomycosis	0.002	0.998	0.000
A37 Whooping cough	0.002	0.998	0.000
A36 Diphtheria	0.002	0.998	0.000
A32 Listeriosis	0.002	0.998	0.000
A30 Leprosy [Hansen's disease]	0.002	0.998	0.000
A38 Scarlet fever	0.002	0.998	0.000
A35 Other tetanus	0.002	0.998	0.000
A34 Obstetrical tetanus	0.002	0.998	0.000
A33 Tetanus neonatorum	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
B99-B99 Other infectious diseases	0.002	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
B50-B64 Protozoal diseases	0.002	0.998	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.998	0.002
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
E13.9 Without complications	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.002	0.998	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.002	0.998	0.000
B50 Plasmodium falciparum malaria	0.002	0.998	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
N25.0 Renal osteodystrophy	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
B82 Unspecified intestinal parasitism	0.001	0.998	0.001
B81 Other intestinal helminthiases, not elsewhere classified	0.001	0.998	0.001
B78 Strongyloidiasis	0.001	0.998	0.001
B77 Ascariasis	0.001	0.998	0.001
B76 Hookworm diseases	0.001	0.998	0.001
B74 Filariasis	0.001	0.998	0.001
B71 Other cestode infections	0.001	0.998	0.001
B70 Diphyllobothriasis and sparganosis	0.001	0.998	0.001
B69 Cysticercosis	0.001	0.998	0.001
B68 Taeniasis	0.001	0.998	0.001
B67 Echinococcosis	0.001	0.998	0.001
B66 Other fluke infections	0.001	0.998	0.001
B65 Schistosomiasis [bilharziasis]	0.001	0.998	0.001
B79 Trichuriasis	0.001	0.998	0.001
B75 Trichinellosis	0.001	0.998	0.001
B73 Onchocerciasis	0.001	0.998	0.001
B72 Dracunculiasis	0.001	0.998	0.001
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
N27 Small kidney of unknown cause	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
A31 Infection due to other mycobacteria	0.002	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
B83 Other helminthiases	0.001	0.998	0.001
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.998	0.002
K11.3 Abscess of salivary gland	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.001	0.998	0.001
Q11.1 Other anophthalmos	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
C57.8 Overlapping lesion of female genital organs	0.002	0.998	0.000
C57.7 Other specified female genital organs	0.002	0.998	0.000
C57.4 Uterine adnexa, unspecified	0.002	0.998	0.000
C57.3 Parametrium	0.002	0.998	0.000
C57.2 Round ligament	0.002	0.998	0.000
C57.1 Broad ligament	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
N27.0 Small kidney, unilateral	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
I80 Phlebitis and thrombophlebitis	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.998	0.002
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
A15-A19 Tuberculosis	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.000	0.998	0.002
L57.4 Cutis laxa senilis	0.002	0.998	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations