TreeWAS – Variant ID: rs12601558

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z43.2 Attention to ileostomy	0.000	0.786	0.214
R47.0 Dysphasia and aphasia	0.000	0.939	0.061
J35.1 Hypertrophy of tonsils	0.028	0.972	0.000
R41.0 Disorientation, unspecified	0.000	0.975	0.025
R47 Speech disturbances, not elsewhere classified	0.000	0.976	0.024
J35.0 Chronic tonsillitis	0.022	0.978	0.000
J35 Chronic diseases of tonsils and adenoids	0.020	0.980	0.000
R47.1 Dysarthria and anarthria	0.000	0.984	0.016
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.014	0.986	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.986	0.014
J35.2 Hypertrophy of adenoids	0.013	0.987	0.000
C78.2 Secondary malignant neoplasm of pleura	0.013	0.987	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.012	0.988	0.000
S82.20 Fracture of shaft of tibia (closed)	0.011	0.989	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.990	0.010
R47-R49 Symptoms and signs involving speech and voice	0.000	0.991	0.009
Q61.3 Polycystic kidney, unspecified	0.008	0.992	0.000
Q61 Cystic kidney disease	0.008	0.992	0.000
Z43 Attention to artificial openings	0.000	0.992	0.008
Q66.8 Other congenital deformities of feet	0.008	0.992	0.000
K74.3 Primary biliary cirrhosis	0.008	0.992	0.000
K74.0 Hepatic fibrosis	0.008	0.992	0.000
H36.0 Diabetic retinopathy	0.007	0.993	0.000
Q61.5 Medullary cystic kidney	0.007	0.993	0.000
K74 Fibrosis and cirrhosis of liver	0.007	0.993	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.993	0.007
Q61.0 Congenital single renal cyst	0.007	0.993	0.000
Q61.9 Cystic kidney disease, unspecified	0.007	0.993	0.000
Q61.4 Renal dysplasia	0.006	0.993	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.006	0.994	0.000
Q61.2 Polycystic kidney, adult type	0.006	0.994	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.994	0.006
Q66 Congenital deformities of feet	0.006	0.994	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.006	0.994	0.000
K74.6 Other and unspecified cirrhosis of liver	0.006	0.994	0.000
H52.1 Myopia	0.006	0.994	0.000
Q61.8 Other cystic kidney diseases	0.006	0.994	0.000
Q61.1 Polycystic kidney, infantile type	0.006	0.994	0.000
Z43.9 Attention to unspecified artificial opening	0.000	0.994	0.006
Z43.7 Attention to artificial vagina	0.000	0.994	0.006
Z43.0 Attention to tracheostomy	0.000	0.994	0.006
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.994	0.006
S22.30 Fracture of rib (closed)	0.000	0.994	0.006
K74.5 Biliary cirrhosis, unspecified	0.005	0.994	0.000
R49 Voice disturbances	0.000	0.994	0.006
K74.4 Secondary biliary cirrhosis	0.005	0.994	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.005	0.994	0.000
K74.1 Hepatic sclerosis	0.005	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.995	0.005
Z43.5 Attention to cyctostomy	0.000	0.995	0.005
S22.3 Fracture of rib	0.000	0.995	0.005
Z35.0 Supervision of pregnancy with history of infertility	0.005	0.995	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.995	0.005
Q66.0 Talipes equinovarus	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
H36 Retinal disorders in diseases classified elsewhere	0.005	0.995	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.995	0.005
R48.2 Apraxia	0.000	0.995	0.005
R48.1 Agnosia	0.000	0.995	0.005
R48.0 Dyslexia and alexia	0.000	0.995	0.005
Z43.8 Attention to other artificial openings	0.000	0.995	0.005
C78.0 Secondary malignant neoplasm of lung	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.995	0.005
C20 Malignant neoplasm of rectum	0.000	0.995	0.005
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.995	0.000
S22.5 Flail chest	0.000	0.996	0.004
R49.8 Other and unspecified voice disturbances	0.000	0.996	0.004
Z43.1 Attention to gastrostomy	0.000	0.996	0.004
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
H33.2 Serous retinal detachment	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
R49.2 Hypernasality and hyponasality	0.000	0.996	0.004
F22.0 Delusional disorder	0.000	0.996	0.004
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
S22.31 Fracture of rib (open)	0.000	0.996	0.004
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.996	0.004
S22.8 Fracture of other parts of bony thorax	0.000	0.996	0.004
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.000	0.996	0.004
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q70.3 Webbed toes	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
R49.0 Dysphonia	0.000	0.996	0.004
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.996	0.004
D27 Benign neoplasm of ovary	0.000	0.996	0.004
R49.1 Aphonia	0.000	0.996	0.003
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q51.3 Bicornate uterus	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.996	0.000
Q53 Undescended testicle	0.003	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.996	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
S22.51 Flail chest (open)	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
I74.8 Embolism and thrombosis of other arteries	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.997	0.003
Q65 Congenital deformities of hip	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
H30-H36 Disorders of choroid and retina	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
Q62.5 Duplication of ureter	0.003	0.997	0.000
H52.2 Astigmatism	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.003
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.003
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.003
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.003
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
N20.2 Calculus of kidney with calculus of ureter	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
K08.3 Retained dental root	0.000	0.997	0.003
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
S22.2 Fracture of sternum	0.000	0.997	0.003
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
H31 Other disorders of choroid	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
K76 Other diseases of liver	0.003	0.997	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
H33 Retinal detachments and breaks	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
K76.9 Liver disease, unspecified	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.997	0.003
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
H52 Disorders of refraction and accommodation	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
M24.2 Disorder of ligament	0.000	0.997	0.003
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.997	0.003
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.997	0.003
Q74.1 Congenital malformation of knee	0.002	0.997	0.000
G95 Other diseases of spinal cord	0.000	0.997	0.003
K70-K77 Diseases of liver	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
F22 Persistent delusional disorders	0.000	0.997	0.003
Q65.9 Congenital deformity of hip, unspecified	0.002	0.997	0.000
Q65.6 Unstable hip	0.002	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.997	0.000
Q33 Congenital malformations of lung	0.002	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.997	0.000
Q31 Congenital malformations of larynx	0.002	0.997	0.000
Q30 Congenital malformations of nose	0.002	0.997	0.000
Q37 Cleft palate with cleft lip	0.002	0.997	0.000
Q36 Cleft lip	0.002	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q54.8 Other hypospadias	0.002	0.997	0.000
Q54.4 Congenital chordee	0.002	0.997	0.000
Q54.3 Hypospadias, perineal	0.002	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.997	0.000
Q98.5 Karyotype 47,XYY	0.002	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.002	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.002	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.997	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.003	0.997	0.000
H34.0 Transient retinal artery occlusion	0.002	0.997	0.000
O72.0 Third-stage haemorrhage	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.002	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q03 Congenital hydrocephalus	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.002	0.997	0.000
Z43.3 Attention to colostomy	0.000	0.997	0.002
H32 Chorioretinal disorders in diseases classified elsewhere	0.002	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.997	0.000
E11.3 With ophthalmic complications	0.003	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.997	0.000
Q07 Other congenital malformations of nervous system	0.002	0.997	0.000
H30 Chorioretinal inflammation	0.002	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.997	0.000
Q52.3 Imperforate hymen	0.002	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.997	0.000
Q52.1 Doubling of vagina	0.002	0.997	0.000
Q52.0 Congenital absence of vagina	0.002	0.997	0.000
Q54.0 Hypospadias, balanic	0.002	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.997	0.000
Q10.0 Congenital ptosis	0.002	0.997	0.000
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
M24 Other specific joint derangements	0.000	0.998	0.002
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
M24.1 Other articular cartilage disorders	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.000	0.998	0.002
H31.9 Disorder of choroid, unspecified	0.002	0.998	0.000
H31.4 Choroidal detachment	0.002	0.998	0.000
H31.2 Hereditary choroidal dystrophy	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.000	0.998	0.002
K76.5 Hepatic veno-occlusive disease	0.002	0.998	0.000
K76.4 Peliosis hepatis	0.002	0.998	0.000
K76.3 Infarction of liver	0.002	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.998	0.002
H52.4 Presbyopia	0.002	0.998	0.000
M24.5 Contracture of joint	0.000	0.998	0.002
H31.0 Chorioretinal scars	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.998	0.000
Q91.6 Trisomy 13, translocation	0.002	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.998	0.000
Q91.2 Trisomy 18, translocation	0.002	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.998	0.000
Q92.7 Triploidy and polyploidy	0.002	0.998	0.000
Q92.6 Extra marker chromosomes	0.002	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.998	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.998	0.000
Q92.3 Minor partial trisomy	0.002	0.998	0.000
Q92.2 Major partial trisomy	0.002	0.998	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.002	0.998	0.000
Q93.9 Deletion from autosomes, unspecified	0.002	0.998	0.000
Q93.8 Other deletions from the autosomes	0.002	0.998	0.000
Q93.7 Deletions with other complex rearrangements	0.002	0.998	0.000
Q93.6 Deletions seen only at prometaphase	0.002	0.998	0.000
Q93.5 Other deletions of part of a chromosome	0.002	0.998	0.000
Q93.4 Deletion of short arm of chromosome 5	0.002	0.998	0.000
Q93.3 Deletion of short arm of chromosome 4	0.002	0.998	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.002	0.998	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.002	0.998	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.002	0.998	0.000
Q95.8 Other balanced rearrangements and structural markers	0.002	0.998	0.000
Q95.5 Individuals with autosomal fragile site	0.002	0.998	0.000
Q95.4 Individuals with marker heterochromatin	0.002	0.998	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.002	0.998	0.000
Q95.1 Chromosome inversion in normal individual	0.002	0.998	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.002	0.998	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.002	0.998	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.002	0.998	0.000
Q97.3 Female with 46,XY karyotype	0.002	0.998	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.002	0.998	0.000
Q97.1 Female with more than three X chromosomes	0.002	0.998	0.000
Q97.0 Karyotype 47,XXX	0.002	0.998	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.998	0.000
Q99.2 Fragile X chromosome	0.002	0.998	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.998	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations