TreeWAS – Variant ID: rs12621256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.901	0.099
J84 Other interstitial pulmonary diseases	0.000	0.924	0.076
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.931	0.069
H33.2 Serous retinal detachment	0.066	0.934	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.942	0.058
J84.0 Alveolar and parietoalveolar conditions	0.000	0.945	0.055
H33 Retinal detachments and breaks	0.053	0.947	0.000
H33.0 Retinal detachment with retinal break	0.052	0.948	0.000
H33.1 Retinoschisis and retinal cysts	0.047	0.953	0.000
H33.5 Other retinal detachments	0.040	0.960	0.000
H33.4 Traction detachment of retina	0.037	0.963	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.983	0.017
D73.0 Hyposplenism	0.000	0.986	0.014
N17.9 Acute renal failure, unspecified	0.000	0.987	0.013
E87.2 Acidosis	0.000	0.987	0.013
H36.0 Diabetic retinopathy	0.000	0.987	0.013
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.012	0.988	0.000
O47 False labour	0.011	0.989	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.011	0.989	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.989	0.011
O30 Multiple gestation	0.011	0.989	0.000
O43.1 Malformation of placenta	0.011	0.989	0.000
O43 Placental disorders	0.011	0.989	0.000
J81 Pulmonary oedema	0.000	0.989	0.011
O30.0 Twin pregnancy	0.011	0.989	0.000
O41 Other disorders of amniotic fluid and membranes	0.011	0.989	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.010	0.990	0.000
O41.0 Oligohydramnios	0.010	0.990	0.000
O32.0 Maternal care for unstable lie	0.010	0.990	0.000
O47.0 False labour before 37 completed weeks of gestation	0.010	0.990	0.000
O32.3 Maternal care for face, brow and chin presentation	0.010	0.990	0.000
J80 Adult respiratory distress syndrome	0.000	0.990	0.010
O32.4 Maternal care for high head at term	0.010	0.990	0.000
O40 Polyhydramnios	0.009	0.991	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.009	0.991	0.000
O36 Maternal care for other known or suspected foetal problems	0.009	0.991	0.000
S42.20 Fracture of upper end of humerus (closed)	0.009	0.991	0.000
O33 Maternal care for known or suspected disproportion	0.009	0.991	0.000
O32.2 Maternal care for transverse and oblique lie	0.009	0.991	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.009	0.991	0.000
O31 Complications specific to multiple gestation	0.008	0.991	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.009	0.991	0.000
O32.6 Maternal care for compound presentation	0.008	0.992	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.008	0.992	0.000
O30.9 Multiple gestation, unspecified	0.008	0.992	0.000
O30.8 Other multiple gestation	0.008	0.992	0.000
O30.2 Quadruplet pregnancy	0.008	0.992	0.000
O30.1 Triplet pregnancy	0.008	0.992	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.008	0.992	0.000
O43.9 Placental disorder, unspecified	0.008	0.992	0.000
O43.2 Morbidly adherent placenta	0.008	0.992	0.000
O43.0 Placental transfusion syndromes	0.008	0.992	0.000
O45 Premature separation of placenta [abruptio placentae]	0.008	0.992	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.008	0.992	0.000
O41.1 Infection of amniotic sac and membranes	0.008	0.992	0.000
S42.2 Fracture of upper end of humerus	0.008	0.992	0.000
O32.8 Maternal care for other malpresentation of foetus	0.008	0.992	0.000
O48 Prolonged pregnancy	0.008	0.992	0.000
O42 Premature rupture of membranes	0.008	0.992	0.000
O47.9 False labour, unspecified	0.007	0.992	0.000
O36.1 Maternal care for other isoimmunisation	0.007	0.993	0.000
S42.00 Fracture of clavicle (closed)	0.007	0.993	0.000
O36.6 Maternal care for excessive foetal growth	0.007	0.993	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.007	0.993	0.000
O36.5 Maternal care for poor foetal growth	0.007	0.993	0.000
O44 Placenta praevia	0.007	0.993	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.007	0.993	0.000
S42.0 Fracture of clavicle	0.007	0.993	0.000
S42 Fracture of shoulder and upper arm	0.007	0.993	0.000
O33.9 Maternal care for disproportion, unspecified	0.007	0.993	0.000
O46.8 Other antepartum haemorrhage	0.007	0.993	0.000
O36.4 Maternal care for intra-uterine death	0.007	0.993	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.007	0.993	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.007	0.993	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.007	0.993	0.000
O36.2 Maternal care for hydrops foetalis	0.007	0.993	0.000
O33.8 Maternal care for disproportion of other origin	0.006	0.993	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.006	0.993	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.006	0.993	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.006	0.993	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.006	0.993	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.006	0.993	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.006	0.993	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.006	0.993	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.006	0.993	0.000
H36 Retinal disorders in diseases classified elsewhere	0.001	0.993	0.006
O36.9 Maternal care for foetal problem, unspecified	0.006	0.994	0.000
O31.8 Other complications specific to multiple gestation	0.006	0.994	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.006	0.994	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.006	0.994	0.000
O31.0 Papyraceous foetus	0.006	0.994	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.006	0.994	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.006	0.994	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.006	0.994	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.006	0.994	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.006	0.994	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.006	0.994	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.006	0.994	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.006	0.994	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.006	0.994	0.000
O43.8 Other placental disorders	0.006	0.994	0.000
O34.4 Maternal care for other abnormalities of cervix	0.006	0.994	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.006	0.994	0.000
N17 Acute renal failure	0.000	0.994	0.006
S46 Injury of muscle and tendon at shoulder and upper arm level	0.006	0.994	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.006	0.994	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.006	0.994	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.006	0.994	0.000
O34.6 Maternal care for abnormality of vagina	0.006	0.994	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.006	0.994	0.000
O34.0 Maternal care for congenital malformation of uterus	0.006	0.994	0.000
O34.3 Maternal care for cervical incompetence	0.006	0.994	0.000
O45.8 Other premature separation of placenta	0.006	0.994	0.000
O45.0 Premature separation of placenta with coagulation defect	0.006	0.994	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.006	0.994	0.000
S42.21 Fracture of upper end of humerus (open)	0.006	0.994	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.006	0.994	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.006	0.994	0.000
N39.3 Stress incontinence	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.006	0.994	0.000
O34.1 Maternal care for tumour of corpus uteri	0.006	0.994	0.000
O36.8 Maternal care for other specified foetal problems	0.006	0.994	0.000
O32.1 Maternal care for breech presentation	0.006	0.994	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.006	0.994	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.006	0.994	0.000
D73 Diseases of spleen	0.000	0.994	0.006
S42.01 Fracture of clavicle (open)	0.005	0.995	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.005	0.995	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.995	0.005
O45.9 Premature separation of placenta, unspecified	0.005	0.995	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.005	0.995	0.000
S40-S49 Injuries to the shoulder and upper arm	0.005	0.995	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.005	0.995	0.000
S42.3 Fracture of shaft of humerus	0.005	0.995	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.005	0.995	0.000
O44.1 Placenta praevia with haemorrhage	0.005	0.995	0.000
N20.0 Calculus of kidney	0.000	0.995	0.005
H36.8 Other retinal disorders in diseases classified elsewhere	0.001	0.995	0.004
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.005	0.995	0.000
S42.1 Fracture of scapula	0.005	0.995	0.000
N17.2 Acute renal failure with medullary necrosis	0.000	0.995	0.005
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.995	0.005
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.005	0.995	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.005	0.995	0.000
S46.3 Injury of muscle and tendon of triceps	0.005	0.995	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.005	0.995	0.000
H33.3 Retinal breaks without detachment	0.004	0.995	0.000
Z01.6 Radiological examination, not elsewhere classified	0.005	0.995	0.000
N17.8 Other acute renal failure	0.000	0.995	0.005
Y40.8 Other systemic antibiotics	0.005	0.995	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.004	0.995	0.000
M54.22 Cervicalgia (Cervical region)	0.005	0.995	0.000
Y40.0 Penicillins	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.000	0.996	0.004
D73.4 Cyst of spleen	0.000	0.996	0.004
D73.3 Abscess of spleen	0.000	0.996	0.004
D73.2 Chronic congestive splenomegaly	0.000	0.996	0.004
D73.5 Infarction of spleen	0.000	0.996	0.004
S41 Open wound of shoulder and upper arm	0.004	0.996	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.004	0.996	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.004	0.996	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.996	0.004
S40 Superficial injury of shoulder and upper arm	0.004	0.996	0.000
S48 Traumatic amputation of shoulder and upper arm	0.004	0.996	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S44 Injury of nerves at shoulder and upper arm level	0.004	0.996	0.000
S47 Crushing injury of shoulder and upper arm	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
S42.31 Fracture of shaft of humerus (open)	0.004	0.996	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.004	0.996	0.000
M22.2 Patellofemoral disorders	0.004	0.996	0.000
Z93.3 Colostomy status	0.004	0.996	0.000
S42.4 Fracture of lower end of humerus	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.000	0.996	0.004
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
D73.1 Hypersplenism	0.000	0.996	0.004
S42.11 Fracture of scapula (open)	0.004	0.996	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.003	0.996	0.000
S41.1 Open wound of upper arm	0.004	0.996	0.000
N20 Calculus of kidney and ureter	0.000	0.996	0.004
Y40.6 Rifamycins	0.003	0.996	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
N20.9 Urinary calculus, unspecified	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.003	0.997	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.003	0.997	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.003	0.997	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.003	0.997	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.003	0.997	0.000
S44.4 Injury of musculocutaneous nerve	0.003	0.997	0.000
S44.3 Injury of axillary nerve	0.003	0.997	0.000
S44.2 Injury of radial nerve at upper arm level	0.003	0.997	0.000
S44.1 Injury of median nerve at upper arm level	0.003	0.997	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.003	0.997	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.003	0.997	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.003	0.997	0.000
S45.2 Injury of axillary or brachial vein	0.003	0.997	0.000
S45.1 Injury of brachial artery	0.003	0.997	0.000
S45.0 Injury of axillary artery	0.003	0.997	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.003	0.997	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.003	0.997	0.000
S48.0 Traumatic amputation at shoulder joint	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
Z01.8 Other specified special examinations	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
N19 Unspecified renal failure	0.000	0.997	0.003
N20.2 Calculus of kidney with calculus of ureter	0.000	0.997	0.003
Z93.5 Cystostomy status	0.003	0.997	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.003	0.997	0.000
C56 Malignant neoplasm of ovary	0.003	0.997	0.000
S42.41 Fracture of lower end of humerus (open)	0.003	0.997	0.000
Z93.1 Gastrostomy status	0.003	0.997	0.000
S41.0 Open wound of shoulder	0.003	0.997	0.000
S40.0 Contusion of shoulder and upper arm	0.003	0.997	0.000
M54.2 Cervicalgia	0.003	0.997	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
Z93 Artificial opening status	0.003	0.997	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.003	0.997	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.003	0.997	0.000
N20.1 Calculus of ureter	0.000	0.997	0.003
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
N17-N19 Renal failure	0.000	0.997	0.003
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.997	0.003
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.002	0.997	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
Z01.2 Dental examination	0.002	0.997	0.000
Z93.0 Tracheostomy status	0.002	0.997	0.000
H30-H36 Disorders of choroid and retina	0.002	0.997	0.001
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.29 Cervicalgia-Site unspe	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.998	0.000
M54.27 Cervicalgia-Lumbosacral	0.002	0.998	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.998	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.998	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.998	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.20 Cervicalgia-Mult site	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
Z93.8 Other artificial opening status	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
Z01.3 Examination of blood pressure	0.002	0.998	0.000
Z01.1 Examination of ears and hearing	0.002	0.998	0.000
Z01.0 Examination of eyes and vision	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
Z93.9 Artificial opening status, unspecified	0.002	0.998	0.000
Z01.7 Laboratory examination	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
M22.0 Recurrent dislocation of patella	0.002	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.001	0.998	0.001
H30 Chorioretinal inflammation	0.001	0.998	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
G30.8 Other Alzheimer's disease	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
M54.6 Pain in thoracic spine	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.001	0.998	0.001
M22.8 Other disorders of patella	0.002	0.998	0.000
H31 Other disorders of choroid	0.001	0.998	0.001
D07.5 Prostate	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
H30.9 Chorioretinal inflammation, unspecified	0.001	0.998	0.001
H30.8 Other chorioretinal inflammations	0.001	0.998	0.001
H30.2 Posterior cyclitis	0.001	0.998	0.001
H30.1 Disseminated chorioretinal inflammation	0.001	0.998	0.001
H30.0 Focal chorioretinal inflammation	0.001	0.998	0.001
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.001	0.998	0.001
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.001
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
N39.4 Other specified urinary incontinence	0.002	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.001
H16.0 Corneal ulcer	0.002	0.998	0.000
M22.3 Other derangements of patella	0.002	0.998	0.000
C95.9 Leukaemia, unspecified	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
Z01.9 Special examination, unspecified	0.002	0.998	0.000
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.001	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.001	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.001	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.001	0.998	0.000
H16.3 Interstitial and deep keratitis	0.001	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
H31.9 Disorder of choroid, unspecified	0.001	0.998	0.001
H31.4 Choroidal detachment	0.001	0.998	0.001
H31.3 Choroidal haemorrhage and rupture	0.001	0.998	0.001
H31.2 Hereditary choroidal dystrophy	0.001	0.998	0.001
H31.1 Choroidal degeneration	0.001	0.998	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
H21.0 Hyphaema	0.001	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.001
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.001	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
K55.8 Other vascular disorders of intestine	0.000	0.998	0.002
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.001	0.998	0.000
D74 Methaemoglobinaemia	0.000	0.998	0.001
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.998	0.001
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.998	0.001
H31.8 Other specified disorders of choroid	0.001	0.998	0.001
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.001	0.998	0.000
O03.4 Incomplete, without complication	0.000	0.998	0.001
H20.2 Lens-induced iridocyclitis	0.001	0.999	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.001	0.999	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.001	0.999	0.000
Y42.5 Other oestrogens and progestogens	0.001	0.999	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.999	0.001
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.999	0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.999	0.001
M54.8 Other dorsalgia	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
Z48.9 Surgical follow-up care, unspecified	0.001	0.999	0.000
I61 Intracerebral haemorrhage	0.001	0.999	0.000
H31.0 Chorioretinal scars	0.001	0.999	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.999	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.999	0.001
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.999	0.001
M54.84 Other dorsalgia (Thoracic region)	0.001	0.999	0.000
H20.0 Acute and subacute iridocyclitis	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000
K55.2 Angiodysplasia of colon	0.000	0.999	0.001
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
G83.8 Other specified paralytic syndromes	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.999	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.001	0.999	0.000
O14.2 HELLP syndrome	0.000	0.999	0.001
O14.1 Severe preeclampsia	0.000	0.999	0.001
D68 Other coagulation defects	0.000	0.999	0.001
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H15 Disorders of sclera	0.001	0.999	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.999	0.001
D74.9 Methaemoglobinaemia, unspecified	0.000	0.999	0.001
D74.8 Other methaemoglobinaemias	0.000	0.999	0.001
D74.0 Congenital methaemoglobinaemia	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.999	0.001
I27 Other pulmonary heart diseases	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.999	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
C71.9 Brain, unspecified	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
H34 Retinal vascular occlusions	0.001	0.999	0.001
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.999	0.001
D68.6 Other Thrombophilia	0.000	0.999	0.001
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.999	0.001
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.999	0.001
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.999	0.001
F41.8 Other specified anxiety disorders	0.001	0.999	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.001	0.999	0.000
H20.1 Chronic iridocyclitis	0.001	0.999	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.001	0.999	0.000
M54.86 Other dorsalgia (Lumbar region)	0.001	0.999	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.001	0.999	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.001	0.999	0.000
M54.82 Other dorsalgia (Cervical region)	0.001	0.999	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.999	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
K55 Vascular disorders of intestine	0.000	0.999	0.001
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.001	0.999	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.001	0.999	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.001	0.999	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.001	0.999	0.000
H52.2 Astigmatism	0.000	0.999	0.001
S43.0 Dislocation of shoulder joint	0.001	0.999	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.001	0.999	0.000
Z93.6 Other artificial openings of urinary tract status	0.001	0.999	0.000
D75.0 Familial erythrocytosis	0.000	0.999	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.999	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.999	0.001
K60.2 Anal fissure, unspecified	0.000	0.999	0.001
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.999	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.001	0.999	0.000
H18 Other disorders of cornea	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.999	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.000	0.999	0.001
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
H15.9 Disorder of sclera, unspecified	0.001	0.999	0.000
H15.8 Other disorders of sclera	0.001	0.999	0.000
H15.1 Episcleritis	0.001	0.999	0.000
H15.0 Scleritis	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.999	0.001
I27.1 Kyphoscoliotic heart disease	0.000	0.999	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.999	0.001
D72 Other disorders of white blood cells	0.000	0.999	0.001
F00 Dementia in Alzheimer's disease	0.000	0.999	0.001
H17 Corneal scars and opacities	0.001	0.999	0.000
D76.3 Other histiocytosis syndromes	0.000	0.999	0.001
N39 Other disorders of urinary system	0.001	0.999	0.000
D75.2 Essential thrombocytosis	0.000	0.999	0.001
H34.9 Retinal vascular occlusion, unspecified	0.001	0.999	0.001
H34.0 Transient retinal artery occlusion	0.001	0.999	0.001
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.999	0.000
W20.0 Home	0.001	0.999	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.999	0.001
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.999	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.999	0.001
S06.5 Traumatic subdural haemorrhage	0.001	0.999	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.999	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.999	0.001
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
H34.1 Central retinal artery occlusion	0.001	0.999	0.001
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.999	0.001
R06.8 Other and unspecified abnormalities of breathing	0.000	0.999	0.001
O03 Spontaneous abortion	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.999	0.001
D72.0 Genetic anomalies of leukocytes	0.000	0.999	0.001
E11.3 With ophthalmic complications	0.000	0.999	0.001
H17.1 Other central corneal opacity	0.001	0.999	0.000
H17.0 Adherent leukoma	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations