TreeWAS – Variant ID: rs12637471

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G20 Parkinson's disease	0.000	0.751	0.249
G20-G26 Extrapyramidal and movement disorders	0.000	0.934	0.066
H50.1 Divergent concomitant strabismus	0.000	0.934	0.066
G23 Other degenerative diseases of basal ganglia	0.000	0.952	0.048
G21 Secondary Parkinsonism	0.000	0.952	0.048
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.952	0.048
G22 Parkinsonism in diseases classified elsewhere	0.000	0.952	0.048
G24 Dystonia	0.000	0.953	0.047
H50 Other strabismus	0.000	0.961	0.039
G24.8 Other dystonia	0.000	0.965	0.035
G21.9 Secondary Parkinsonism, unspecified	0.000	0.965	0.034
G21.8 Other secondary Parkinsonism	0.000	0.965	0.034
G21.4 Vascular parkinsonism	0.000	0.965	0.034
G21.3 Postencephalitic Parkinsonism	0.000	0.965	0.034
G21.2 Secondary Parkinsonism due to other external agents	0.000	0.965	0.034
G21.1 Other drug-induced secondary Parkinsonism	0.000	0.965	0.034
G21.0 Malignant neuroleptic syndrome	0.000	0.965	0.034
G23.9 Degenerative disease of basal ganglia, unspecified	0.000	0.965	0.034
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.965	0.034
G23.3 Multiple system atrophy, cerebellar type	0.000	0.965	0.034
G23.2 Striatonigral degeneration	0.000	0.965	0.034
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.000	0.965	0.034
G23.0 Hallervorden-Spatz disease	0.000	0.965	0.034
G24.3 Spasmodic torticollis	0.000	0.966	0.034
G24.4 Idiopathic orofacial dystonia	0.000	0.966	0.034
G24.2 Idiopathic nonfamilial dystonia	0.000	0.966	0.034
G24.1 Idiopathic familial dystonia	0.000	0.966	0.034
G24.0 Drug-induced dystonia	0.000	0.966	0.034
H50.2 Vertical strabismus	0.000	0.966	0.034
G24.9 Dystonia, unspecified	0.000	0.967	0.033
H50.4 Other and unspecified heterotropia	0.000	0.968	0.032
R05 Cough	0.000	0.968	0.032
G24.5 Blepharospasm	0.000	0.968	0.032
H50.5 Heterophoria	0.000	0.969	0.031
G25 Other extrapyramidal and movement disorders	0.000	0.969	0.031
H50.8 Other specified strabismus	0.000	0.971	0.029
H50.6 Mechanical strabismus	0.000	0.971	0.028
H50.3 Intermittent heterotropia	0.000	0.971	0.028
G25.3 Myoclonus	0.000	0.974	0.026
G25.2 Other specified forms of tremor	0.000	0.976	0.024
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.977	0.022
G25.5 Other chorea	0.000	0.977	0.022
G25.4 Drug-induced chorea	0.000	0.977	0.022
G25.1 Drug-induced tremor	0.000	0.977	0.022
H50.0 Convergent concomitant strabismus	0.000	0.977	0.022
N28.1 Cyst of kidney, acquired	0.021	0.979	0.000
H50.9 Strabismus, unspecified	0.000	0.981	0.019
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.982	0.018
N28 Other disorders of kidney and ureter, not elsewhere classified	0.017	0.983	0.000
N28.8 Other specified disorders of kidney and ureter	0.017	0.983	0.000
N28.0 Ischaemia and infarction of kidney	0.015	0.984	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.985	0.015
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.986	0.014
G25.0 Essential tremor	0.000	0.986	0.013
L57.0 Actinic keratosis	0.012	0.988	0.000
H49 Paralytic strabismus	0.000	0.989	0.011
H51 Other disorders of binocular movement	0.000	0.990	0.010
N25-N29 Other disorders of kidney and ureter	0.009	0.991	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.991	0.009
H49.0 Third [oculomotor] nerve palsy	0.000	0.992	0.008
H49.8 Other paralytic strabismus	0.000	0.992	0.008
H49.4 Progressive external ophthalmoplegia	0.000	0.992	0.008
H49.3 Total (external) ophthalmoplegia	0.000	0.992	0.008
N26 Unspecified contracted kidney	0.008	0.992	0.000
H52 Disorders of refraction and accommodation	0.000	0.992	0.008
H51.9 Disorder of binocular movement, unspecified	0.000	0.992	0.007
H51.8 Other specified disorders of binocular movement	0.000	0.992	0.007
H51.2 Internuclear ophthalmoplegia	0.000	0.992	0.007
H51.1 Convergence insufficiency and excess	0.000	0.992	0.007
H51.0 Palsy of conjugate gaze	0.000	0.992	0.007
H49.1 Fourth [trochlear] nerve palsy	0.000	0.993	0.007
H49.9 Paralytic strabismus, unspecified	0.000	0.993	0.007
N27 Small kidney of unknown cause	0.007	0.993	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.007	0.993	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.993	0.007
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.993	0.007
K59.8 Other specified functional intestinal disorders	0.000	0.993	0.007
Z97.4 Presence of external hearing-aid	0.007	0.993	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.994	0.006
L57 Skin changes due to chronic exposure to nonionising radiation	0.006	0.994	0.000
H47.2 Optic atrophy	0.006	0.994	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.006	0.994	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.006	0.994	0.000
H52.2 Astigmatism	0.000	0.994	0.006
N28.9 Disorder of kidney and ureter, unspecified	0.006	0.994	0.000
H52.6 Other disorders of refraction	0.000	0.994	0.006
H52.5 Disorders of accommodation	0.000	0.994	0.006
N27.9 Small kidney, unspecified	0.006	0.994	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.994	0.006
N25 Disorders resulting from impaired renal tubular function	0.005	0.994	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.994	0.005
H47.5 Disorders of other visual pathways	0.005	0.995	0.000
N27.0 Small kidney, unilateral	0.005	0.995	0.000
H52.0 Hypermetropia	0.000	0.995	0.005
H52.4 Presbyopia	0.000	0.995	0.005
N27.1 Small kidney, bilateral	0.005	0.995	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.995	0.005
H52.3 Anisometropia and aniseikonia	0.000	0.995	0.005
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.005	0.995	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.005	0.995	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.995	0.005
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.995	0.005
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.995	0.005
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.995	0.005
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.995	0.005
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.995	0.005
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.995	0.005
L57.5 Actinic granuloma	0.005	0.995	0.000
L57.3 Poikiloderma of Civatte	0.005	0.995	0.000
L57.2 Cutis rhomboidalis nuchae	0.005	0.995	0.000
L57.1 Actinic reticuloid	0.005	0.995	0.000
H52.1 Myopia	0.000	0.995	0.005
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
N29.0 Late syphilis of kidney	0.005	0.995	0.000
H47.7 Disorder of visual pathways, unspecified	0.005	0.995	0.000
H47.6 Disorders of visual cortex	0.005	0.995	0.000
H47.4 Disorders of optic chiasm	0.005	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.004	0.995	0.000
H47.3 Other disorders of optic disk	0.004	0.996	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.004	0.996	0.000
N25.1 Nephrogenic diabetes insipidus	0.004	0.996	0.000
N25.0 Renal osteodystrophy	0.004	0.996	0.000
L57.4 Cutis laxa senilis	0.004	0.996	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.996	0.004
H47.1 Papilloedema, unspecified	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.000	0.996	0.004
H46 Optic neuritis	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.996	0.003
O03.9 Complete or unspecified, without complication	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
K37 Unspecified appendicitis	0.000	0.997	0.003
N25.8 Other disorders resulting from impaired renal tubular function	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.997	0.003
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
G72.0 Drug-induced myopathy	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.997	0.003
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.997	0.003
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.997	0.003
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
R90.0 Intracranial space-occupying lesion	0.003	0.997	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
C71.1 Frontal lobe	0.003	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.997	0.003
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
O03 Spontaneous abortion	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.997	0.003
D35.2 Pituitary gland	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.003	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.997	0.002
Q65 Congenital deformities of hip	0.003	0.997	0.000
M70.6 Trochanteric bursitis	0.000	0.997	0.003
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.002	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
C15.5 Lower third of oesophagus	0.000	0.997	0.003
Q66.7 Pes cavus	0.002	0.997	0.000
C71 Malignant neoplasm of brain	0.002	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.998	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.998	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
G72 Other myopathies	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.998	0.002
O02 Other abnormal products of conception	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.002	0.998	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
O03.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
O02.1 Missed abortion	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
L58 Radiodermatitis	0.002	0.998	0.000
L55 Sunburn	0.002	0.998	0.000
O03.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
L56 Other acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
M70.69 Trochanteric bursitis-Site unspec	0.000	0.998	0.002
M70.68 Trochanteric bursitis-Other	0.000	0.998	0.002
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.998	0.002
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.998	0.002
M70.64 Trochanteric bursitis-Hand	0.000	0.998	0.002
M70.63 Trochanteric bursitis-Forearm	0.000	0.998	0.002
M70.62 Trochanteric bursitis-Upper arm	0.000	0.998	0.002
M70.61 Trochanteric bursitis-Shldr region	0.000	0.998	0.002
M70.60 Trochanteric bursitis-Mult sites	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
G72.8 Other specified myopathies	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
G72.3 Periodic paralysis	0.002	0.998	0.000
G72.2 Myopathy due to other toxic agents	0.002	0.998	0.000
G72.1 Alcoholic myopathy	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.002	0.998	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O00-O08 Pregnancy with abortive outcome	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.000	0.998	0.002
L55.9 Sunburn, unspecified	0.002	0.998	0.000
L55.8 Other sunburn	0.002	0.998	0.000
L55.2 Sunburn of third degree	0.002	0.998	0.000
L55.1 Sunburn of second degree	0.002	0.998	0.000
L55.0 Sunburn of first degree	0.002	0.998	0.000
L58.9 Radiodermatitis, unspecified	0.002	0.998	0.000
L58.1 Chronic radiodermatitis	0.002	0.998	0.000
L58.0 Acute radiodermatitis	0.002	0.998	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.002	0.998	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
Z97.1 Presence of artificial limb (complete)(partial)	0.002	0.998	0.000
L56.4 Polymorphous light eruption	0.002	0.998	0.000
L56.3 Solar urticaria	0.002	0.998	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.002	0.998	0.000
L56.1 Drug photoallergic response	0.002	0.998	0.000
L56.0 Drug phototoxic response	0.002	0.998	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
T71 Asphyxiation	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Z97 Presence of other devices	0.002	0.998	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
T68 Hypothermia	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
H34 Retinal vascular occlusions	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O07 Failed attempted abortion	0.002	0.998	0.000
O06 Unspecified abortion	0.002	0.998	0.000
O05 Other abortion	0.002	0.998	0.000
O01 Hydatidiform mole	0.002	0.998	0.000
O00 Ectopic pregnancy	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations