TreeWAS – Variant ID: rs12641856

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O70.0 First degree perineal laceration during delivery	0.109	0.891	0.000
O70 Perineal laceration during delivery	0.105	0.895	0.000
O60-O75 Complications of labour and delivery	0.100	0.900	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.095	0.905	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.093	0.907	0.000
O70.9 Perineal laceration during delivery, unspecified	0.092	0.908	0.000
O63 Long labour	0.090	0.910	0.000
O63.0 Prolonged first stage (of labour)	0.090	0.910	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.086	0.914	0.000
O61 Failed induction of labour	0.085	0.915	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.084	0.916	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.083	0.917	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.083	0.917	0.000
O73 Retained placenta and membranes, without haemorrhage	0.082	0.918	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.080	0.920	0.000
O69.8 Labour and delivery complicated by other cord complications	0.076	0.924	0.000
O71 Other obstetric trauma	0.076	0.924	0.000
O70.3 Fourth degree perineal laceration during delivery	0.075	0.924	0.000
O61.0 Failed medical induction of labour	0.074	0.926	0.000
O64.1 Obstructed labour due to breech presentation	0.073	0.927	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.073	0.927	0.000
O74 Complications of anaesthesia during labour and delivery	0.072	0.928	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.072	0.928	0.000
O60 Preterm delivery	0.072	0.928	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.070	0.930	0.000
O70.1 Second degree perineal laceration during delivery	0.070	0.930	0.000
O75.0 Maternal distress during labour and delivery	0.070	0.930	0.000
O70.2 Third degree perineal laceration during delivery	0.069	0.931	0.000
O62 Abnormalities of forces of labour	0.069	0.931	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.068	0.931	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.068	0.931	0.000
O69.3 Labour and delivery complicated by short cord	0.068	0.931	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.068	0.931	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.068	0.932	0.000
O75.9 Complication of labour and delivery, unspecified	0.067	0.933	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.067	0.933	0.000
O75.4 Other complications of obstetric surgery and procedures	0.067	0.933	0.000
O75.3 Other infection during labour	0.067	0.933	0.000
O75.1 Shock during or following labour and delivery	0.067	0.933	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.065	0.935	0.000
O61.9 Failed induction of labour, unspecified	0.061	0.939	0.000
O61.8 Other failed induction of labour	0.061	0.939	0.000
O61.1 Failed instrumental induction of labour	0.061	0.939	0.000
O71.7 Obstetric haematoma of pelvis	0.060	0.940	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.060	0.940	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.060	0.940	0.000
O64.5 Obstructed labour due to compound presentation	0.060	0.940	0.000
O64.4 Obstructed labour due to shoulder presentation	0.060	0.940	0.000
O64.3 Obstructed labour due to brow presentation	0.060	0.940	0.000
O64.2 Obstructed labour due to face presentation	0.060	0.940	0.000
O73.0 Retained placenta, without haemorrhage	0.059	0.941	0.000
O71.4 Obstetric high vaginal laceration alone	0.058	0.942	0.000
O62.3 Precipitate labour	0.056	0.944	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.055	0.944	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.055	0.945	0.000
O71.9 Obstetric trauma, unspecified	0.054	0.945	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.054	0.945	0.000
O71.5 Other obstetric injury to pelvic organs	0.054	0.945	0.000
O71.3 Obstetric laceration of cervix	0.054	0.945	0.000
O71.2 Postpartum inversion of uterus	0.054	0.945	0.000
O71.1 Rupture of uterus during labour	0.054	0.945	0.000
O71.0 Rupture of uterus before onset of labour	0.054	0.945	0.000
O66 Other obstructed labour	0.053	0.947	0.000
O60.3 Preterm delivery without spontaneous labour	0.052	0.948	0.000
O60.2 Preterm spontaneous labour with term delivery	0.052	0.948	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.052	0.948	0.000
O60.0 Preterm labour without delivery	0.052	0.948	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.052	0.948	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.052	0.948	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.052	0.948	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.052	0.948	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.052	0.948	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.052	0.948	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.052	0.948	0.000
O65.0 Obstructed labour due to deformed pelvis	0.052	0.948	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.052	0.948	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.052	0.948	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.052	0.948	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.052	0.948	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.052	0.948	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.052	0.948	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.052	0.948	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.052	0.948	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.052	0.948	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.052	0.948	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.051	0.949	0.000
O75.8 Other specified complications of labour and delivery	0.051	0.949	0.000
O67.8 Other intrapartum haemorrhage	0.050	0.950	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.050	0.950	0.000
O62.9 Abnormality of forces of labour, unspecified	0.050	0.950	0.000
O62.8 Other abnormalities of forces of labour	0.050	0.950	0.000
O62.1 Secondary uterine inertia	0.048	0.952	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.048	0.952	0.000
O71.8 Other specified obstetric trauma	0.047	0.953	0.000
O63.1 Prolonged second stage (of labour)	0.046	0.953	0.000
O63.9 Long labour, unspecified	0.044	0.956	0.000
O62.0 Primary inadequate contractions	0.043	0.957	0.000
O62.2 Other uterine inertia	0.043	0.957	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.042	0.958	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.039	0.961	0.000
O66.9 Obstructed labour, unspecified	0.038	0.962	0.000
O66.8 Other specified obstructed labour	0.038	0.962	0.000
O66.4 Failed trial of labour, unspecified	0.038	0.962	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.038	0.962	0.000
O66.2 Obstructed labour due to unusually large foetus	0.038	0.962	0.000
O66.1 Obstructed labour due to locked twins	0.038	0.962	0.000
O72 Postpartum haemorrhage	0.035	0.965	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.032	0.968	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.032	0.968	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.030	0.970	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.028	0.971	0.000
O72.3 Postpartum coagulation defects	0.025	0.975	0.000
H92.0 Otalgia	0.025	0.975	0.000
T85.2 Mechanical complication of intraocular lens	0.024	0.976	0.000
H92 Otalgia and effusion of ear	0.023	0.977	0.000
H90-H95 Other disorders of ear	0.022	0.978	0.000
O72.0 Third-stage haemorrhage	0.021	0.978	0.000
H93 Other disorders of ear, not elsewhere classified	0.021	0.979	0.000
H93.1 Tinnitus	0.020	0.980	0.000
H60-H62 Diseases of external ear	0.020	0.980	0.000
H61 Other disorders of external ear	0.019	0.980	0.000
Chapter VIII Diseases of the ear and mastoid process	0.019	0.981	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.019	0.981	0.000
H61.2 Impacted cerumen	0.019	0.981	0.000
H90 Conductive and sensorineural hearing loss	0.018	0.982	0.000
H65-H75 Diseases of middle ear and mastoid	0.018	0.982	0.000
H71 Cholesteatoma of middle ear	0.018	0.982	0.000
H61.3 Acquired stenosis of external ear canal	0.017	0.983	0.000
H90.5 Sensorineural hearing loss, unspecified	0.017	0.983	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.017	0.983	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.017	0.983	0.000
H61.9 Disorder of external ear, unspecified	0.017	0.983	0.000
H93.8 Other specified disorders of ear	0.017	0.983	0.000
H60 Otitis externa	0.017	0.983	0.000
H92.2 Otorrhagia	0.016	0.983	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.016	0.984	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.016	0.984	0.000
H66 Suppurative and unspecified otitis media	0.016	0.984	0.000
H93.3 Disorders of acoustic nerve	0.015	0.985	0.000
H93.2 Other abnormal auditory perceptions	0.015	0.985	0.000
H93.0 Degenerative and vascular disorders of ear	0.015	0.985	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.015	0.985	0.000
H92.1 Otorrhoea	0.015	0.985	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.015	0.985	0.000
H66.3 Other chronic suppurative otitis media	0.014	0.985	0.000
H93.9 Disorder of ear, unspecified	0.014	0.986	0.000
H61.0 Perichondritis of external ear	0.014	0.986	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.014	0.986	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.014	0.986	0.000
H73 Other disorders of tympanic membrane	0.014	0.986	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.014	0.986	0.000
O72.1 Other immediate postpartum haemorrhage	0.014	0.986	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.014	0.986	0.000
H61.1 Non-infective disorders of pinna	0.014	0.986	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.014	0.986	0.000
H60.9 Otitis externa, unspecified	0.013	0.987	0.000
H60.8 Other otitis externa	0.013	0.987	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.013	0.987	0.000
H90.0 Conductive hearing loss, bilateral	0.013	0.987	0.000
H60.1 Cellulitis of external ear	0.013	0.987	0.000
H74 Other disorders of middle ear and mastoid	0.013	0.987	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.013	0.987	0.000
H68 Eustachian salpingitis and obstruction	0.013	0.987	0.000
H67 Otitis media in diseases classified elsewhere	0.013	0.987	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.013	0.987	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.987	0.013
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.013	0.987	0.000
H90.3 Sensorineural hearing loss, bilateral	0.012	0.987	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.012	0.988	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.012	0.988	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.012	0.988	0.000
H60.5 Acute otitis externa, non-infective	0.012	0.988	0.000
H60.4 Cholesteatoma of external ear	0.012	0.988	0.000
H60.2 Malignant otitis externa	0.012	0.988	0.000
H60.0 Abscess of external ear	0.012	0.988	0.000
H66.4 Suppurative otitis media, unspecified	0.012	0.988	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.012	0.988	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.012	0.988	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.012	0.988	0.000
J84 Other interstitial pulmonary diseases	0.000	0.988	0.012
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.012	0.988	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.988	0.012
H95.1 Other disorders following mastoidectomy	0.012	0.988	0.000
H60.3 Other infective otitis externa	0.012	0.988	0.000
H69 Other disorders of Eustachian tube	0.011	0.988	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.011	0.988	0.000
H66.0 Acute suppurative otitis media	0.011	0.988	0.000
H73.8 Other specified disorders of tympanic membrane	0.011	0.989	0.000
H70 Mastoiditis and related conditions	0.011	0.989	0.000
H74.4 Polyp of middle ear	0.011	0.989	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.010	0.989	0.001
H62.8 Other disorders of external ear in diseases classified elsewhere	0.010	0.989	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.010	0.989	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.010	0.989	0.000
H62.2 Otitis externa in mycoses	0.010	0.989	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.010	0.989	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.010	0.989	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.010	0.990	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.010	0.990	0.000
H73.1 Chronic myringitis	0.010	0.990	0.000
H73.0 Acute myringitis	0.010	0.990	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.010	0.990	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.010	0.990	0.000
H65 Nonsuppurative otitis media	0.010	0.990	0.000
H66.9 Otitis media, unspecified	0.010	0.990	0.000
H61.8 Other specified disorders of external ear	0.009	0.990	0.000
H74.1 Adhesive middle ear disease	0.009	0.990	0.000
H72 Perforation of tympanic membrane	0.009	0.990	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.009	0.990	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.009	0.990	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.009	0.990	0.000
H68.1 Obstruction of Eustachian tube	0.009	0.990	0.000
H68.0 Eustachian salpingitis	0.009	0.990	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.990	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.009	0.990	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.009	0.991	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.009	0.991	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.009	0.991	0.000
H90.2 Conductive hearing loss, unspecified	0.009	0.991	0.000
H91 Other hearing loss	0.009	0.991	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.009	0.991	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.009	0.991	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.991	0.009
J84.0 Alveolar and parietoalveolar conditions	0.000	0.991	0.009
H69.0 Patulous Eustachian tube	0.008	0.991	0.000
H70.8 Other mastoiditis and related conditions	0.008	0.991	0.000
H70.2 Petrositis	0.008	0.991	0.000
H70.1 Chronic mastoiditis	0.008	0.991	0.000
H70.0 Acute mastoiditis	0.008	0.991	0.000
H69.8 Other specified disorders of Eustachian tube	0.008	0.992	0.000
K01.1 Impacted teeth	0.000	0.992	0.008
H65.3 Chronic mucoid otitis media	0.008	0.992	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.992	0.008
H74.0 Tympanosclerosis	0.007	0.993	0.000
H91.1 Presbycusis	0.007	0.993	0.000
H65.1 Other acute nonsuppurative otitis media	0.007	0.993	0.000
H65.0 Acute serous otitis media	0.007	0.993	0.000
H69.9 Eustachian tube disorder, unspecified	0.007	0.993	0.000
H72.1 Attic perforation of tympanic membrane	0.007	0.993	0.000
H70.9 Mastoiditis, unspecified	0.007	0.993	0.000
H72.2 Other marginal perforations of tympanic membrane	0.007	0.993	0.000
H91.3 Deaf mutism, not elsewhere classified	0.007	0.993	0.000
H91.2 Sudden idiopathic hearing loss	0.007	0.993	0.000
H91.0 Ototoxic hearing loss	0.007	0.993	0.000
H72.0 Central perforation of tympanic membrane	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
H65.2 Chronic serous otitis media	0.006	0.993	0.000
J80 Adult respiratory distress syndrome	0.000	0.994	0.006
Q61.2 Polycystic kidney, adult type	0.006	0.994	0.000
J81 Pulmonary oedema	0.000	0.994	0.006
H80-H83 Diseases of inner ear	0.006	0.994	0.000
Q61 Cystic kidney disease	0.006	0.994	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
N35.9 Urethral stricture, unspecified	0.000	0.994	0.006
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.994	0.006
H72.9 Perforation of tympanic membrane, unspecified	0.006	0.994	0.000
H52.1 Myopia	0.006	0.994	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.994	0.000
H91.8 Other specified hearing loss	0.006	0.994	0.000
K90.0 Coeliac disease	0.000	0.995	0.005
H43.8 Other disorders of vitreous body	0.005	0.995	0.000
O85-O92 Complications predominantly related to the puerperium	0.005	0.995	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C34.3 Lower lobe, bronchus or lung	0.005	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
H43.1 Vitreous haemorrhage	0.005	0.995	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.005	0.995	0.000
Q61.9 Cystic kidney disease, unspecified	0.005	0.995	0.000
Q61.8 Other cystic kidney diseases	0.005	0.995	0.000
Q61.5 Medullary cystic kidney	0.005	0.995	0.000
Q61.4 Renal dysplasia	0.005	0.995	0.000
Q61.1 Polycystic kidney, infantile type	0.005	0.995	0.000
O86 Other puerperal infections	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
K01 Embedded and impacted teeth	0.000	0.995	0.005
I84.6 Residual haemorrhoidal skin tags	0.005	0.995	0.000
C34.1 Upper lobe, bronchus or lung	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
H43 Disorders of vitreous body	0.004	0.996	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
C34 Malignant neoplasm of bronchus and lung	0.004	0.996	0.000
D13.1 Stomach	0.000	0.996	0.004
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.000	0.996	0.004
K01.0 Embedded teeth	0.000	0.996	0.004
O86.1 Other infection of genital tract following delivery	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
N94.6 Dysmenorrhoea, unspecified	0.000	0.996	0.004
O91 Infections of breast associated with childbirth	0.004	0.996	0.000
O89 Complications of anaesthesia during the puerperium	0.004	0.996	0.000
O88 Obstetric embolism	0.004	0.996	0.000
O85 Puerperal sepsis	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
H80 Otosclerosis	0.004	0.996	0.000
O90.1 Disruption of perineal obstetric wound	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
O86.8 Other specified puerperal infections	0.004	0.996	0.000
O86.4 Pyrexia of unknown origin following delivery	0.004	0.996	0.000
O86.3 Other genito-urinary tract infections following delivery	0.004	0.996	0.000
O86.2 Urinary tract infection following delivery	0.004	0.996	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
O87 Venous complications in the puerperium	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
O90.9 Complication of the puerperium, unspecified	0.004	0.996	0.000
C34.0 Main bronchus	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
O90.5 Postpartum thyroiditis	0.003	0.996	0.000
O90.4 Postpartum acute renal failure	0.003	0.996	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.996	0.000
O90.2 Haematoma of obstetric wound	0.003	0.996	0.000
O90.0 Disruption of Caesarean section wound	0.003	0.996	0.000
Q63 Other congenital malformations of kidney	0.003	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.996	0.000
H43.9 Disorder of vitreous body, unspecified	0.003	0.996	0.000
W02.9 Unspecified place	0.003	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
H43.2 Crystalline deposits in vitreous body	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
C34.8 Overlapping lesion of bronchus and lung	0.003	0.997	0.000
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
H83 Other diseases of inner ear	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
C34.9 Bronchus or lung, unspecified	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
L72.0 Epidermal cyst	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
H81 Disorders of vestibular function	0.003	0.997	0.000
O41.0 Oligohydramnios	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
O88.8 Other obstetric embolism	0.003	0.997	0.000
O88.3 Obstetric pyaemic and septic embolism	0.003	0.997	0.000
O88.2 Obstetric blood-clot embolism	0.003	0.997	0.000
O88.1 Amniotic fluid embolism	0.003	0.997	0.000
O88.0 Obstetric air embolism	0.003	0.997	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.997	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.997	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.997	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.003	0.997	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.997	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.997	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.003	0.997	0.000
O91.1 Abscess of breast associated with childbirth	0.003	0.997	0.000
O91.0 Infection of nipple associated with childbirth	0.003	0.997	0.000
O80-O84 Delivery	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
H80.8 Other otosclerosis	0.003	0.997	0.000
H80.2 Cochlear otosclerosis	0.003	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.003	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
C71.1 Frontal lobe	0.000	0.997	0.003
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
O87.9 Venous complication in the puerperium, unspecified	0.003	0.997	0.000
O87.8 Other venous complications in the puerperium	0.003	0.997	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.003	0.997	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.003	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.5 Duplication of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
W06.0 Home	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.997	0.000
Q78.6 Multiple congenital exostoses	0.002	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.997	0.000
Q78.4 Enchondromatosis	0.002	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.997	0.000
Q78.2 Osteopetrosis	0.002	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.997	0.000
H83.8 Other specified diseases of inner ear	0.002	0.997	0.000
H83.3 Noise effects on inner ear	0.002	0.997	0.000
H83.2 Labyrinthine dysfunction	0.002	0.997	0.000
H83.1 Labyrinthine fistula	0.002	0.997	0.000
O87.2 Haemorrhoids in the puerperium	0.002	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.002	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.997	0.000
H81.3 Other peripheral vertigo	0.002	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations