TreeWAS – Variant ID: rs12659622

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.347	0.653	0.000
T81 Complications of procedures, not elsewhere classified	0.345	0.655	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.344	0.656	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.329	0.671	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.715	0.285
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.717	0.283
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.278	0.722	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.729	0.271
T39.0 Salicylates	0.000	0.742	0.258
T39.1 4-Aminophenol derivatives	0.000	0.743	0.257
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.744	0.256
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.255	0.744	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.745	0.255
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.748	0.252
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.247	0.752	0.000
T81.9 Unspecified complication of procedure	0.240	0.760	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.765	0.235
T45.0 Antiallergic and antiemetic drugs	0.000	0.766	0.234
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.774	0.225
T81.8 Other complications of procedures, not elsewhere classified	0.225	0.775	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.775	0.225
T81.7 Vascular complications following a procedure, not elsewhere classified	0.223	0.777	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.780	0.220
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.782	0.218
T40.2 Other opioids	0.000	0.783	0.217
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.790	0.210
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.791	0.209
T40.4 Other synthetic narcotics	0.000	0.791	0.209
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.795	0.204
T39.4 Antirheumatics, not elsewhere classified	0.000	0.795	0.204
T39.2 Pyrazolone derivatives	0.000	0.795	0.204
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.796	0.203
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.797	0.203
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.797	0.203
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.797	0.203
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.797	0.203
T36 Poisoning by systemic antibiotics	0.000	0.797	0.203
T40.6 Other and unspecified narcotics	0.000	0.799	0.201
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.799	0.201
T46.1 Calcium-channel blockers	0.000	0.808	0.192
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.809	0.191
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.810	0.190
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.816	0.184
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.816	0.184
T40.8 Lysergide [LSD]	0.000	0.816	0.184
T40.7 Cannabis (derivatives)	0.000	0.816	0.184
T40.5 Cocaine	0.000	0.816	0.184
T40.3 Methadone	0.000	0.816	0.184
T40.1 Heroin	0.000	0.816	0.184
T40.0 Opium	0.000	0.816	0.184
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.817	0.183
T45.8 Other primarily systemic and haematological agents	0.000	0.817	0.183
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.817	0.183
T45.6 Fibrinolysis-affecting drugs	0.000	0.817	0.183
T45.4 Iron and its compounds	0.000	0.817	0.183
T45.3 Enzymes, not elsewhere classified	0.000	0.817	0.183
T45.2 Vitamins, not elsewhere classified	0.000	0.817	0.183
T45.5 Anticoagulants	0.000	0.819	0.181
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.819	0.181
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.819	0.181
T46.7 Peripheral vasodilators	0.000	0.819	0.181
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.819	0.181
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.819	0.181
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.819	0.181
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.819	0.181
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.820	0.180
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.825	0.175
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.828	0.172
T42.1 Iminostilbenes	0.000	0.829	0.171
T50.8 Diagnostic agents	0.000	0.831	0.169
T50.7 Analeptics and opioid receptor antagonists	0.000	0.831	0.169
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.831	0.169
T50.5 Appetite depressants	0.000	0.831	0.169
T50.4 Drugs affecting uric acid metabolism	0.000	0.831	0.169
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.831	0.169
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.831	0.169
T50.1 Loop [high-ceiling] diuretics	0.000	0.831	0.169
T50.0 Mineralocorticoids and their antagonists	0.000	0.831	0.169
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.837	0.163
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.838	0.162
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.838	0.162
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.838	0.162
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.838	0.162
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.838	0.162
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.838	0.162
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.838	0.162
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.838	0.162
T44.0 Anticholinesterase agents	0.000	0.838	0.162
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.838	0.161
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.838	0.161
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.838	0.161
T42.3 Barbiturates	0.000	0.838	0.161
T42.2 Succinimides and oxazolidinediones	0.000	0.838	0.161
T42.0 Hydantoin derivatives	0.000	0.838	0.161
T43.9 Psychotropic drug, unspecified	0.000	0.842	0.158
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.842	0.158
T43.6 Psychostimulants with abuse potential	0.000	0.842	0.158
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.842	0.158
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.842	0.158
T43.2 Other and unspecified antidepressants	0.000	0.843	0.157
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.843	0.157
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.843	0.157
T47.7 Emetics	0.000	0.843	0.157
T47.6 Antidiarrhoeal drugs	0.000	0.843	0.157
T47.5 Digestants	0.000	0.843	0.157
T47.4 Other laxatives	0.000	0.843	0.157
T47.3 Saline and osmotic laxatives	0.000	0.843	0.157
T47.2 Stimulant laxatives	0.000	0.843	0.157
T47.0 Histamine H(2)-receptor antagonists	0.000	0.843	0.157
T36.9 Systemic antibiotic, unspecified	0.000	0.854	0.146
T36.8 Other systemic antibiotics	0.000	0.854	0.146
T36.7 Antifungal antibiotics, systemically used	0.000	0.854	0.146
T36.6 Rifamycins	0.000	0.854	0.146
T36.5 Aminoglycosides	0.000	0.854	0.146
T36.4 Tetracyclines	0.000	0.854	0.146
T36.3 Macrolides	0.000	0.854	0.146
T36.2 Chloramphenicol group	0.000	0.854	0.146
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.854	0.146
T36.0 Penicillins	0.000	0.854	0.146
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.854	0.146
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.854	0.146
T37.5 Antiviral drugs	0.000	0.854	0.146
T37.4 Anthelminthics	0.000	0.854	0.146
T37.3 Other antiprotozoal drugs	0.000	0.854	0.146
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.854	0.146
T37.1 Antimycobacterial drugs	0.000	0.854	0.146
T37.0 Sulphonamides	0.000	0.854	0.146
T41.5 Therapeutic gases	0.000	0.854	0.146
T41.4 Anaesthetic, unspecified	0.000	0.854	0.146
T41.3 Local anaesthetics	0.000	0.854	0.146
T41.2 Other and unspecified general anaesthetics	0.000	0.854	0.146
T41.1 Intravenous anaesthetics	0.000	0.854	0.146
T41.0 Inhaled anaesthetics	0.000	0.854	0.146
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.854	0.146
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.854	0.146
T48.5 Anti-common-cold drugs	0.000	0.854	0.146
T48.4 Expectorants	0.000	0.854	0.146
T48.3 Antitussives	0.000	0.854	0.146
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.854	0.146
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.854	0.146
T48.0 Oxytocic drugs	0.000	0.854	0.146
T49.9 Topical agent, unspecified	0.000	0.854	0.146
T49.8 Other topical agents	0.000	0.854	0.146
T49.7 Dental drugs, topically applied	0.000	0.854	0.146
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.854	0.146
T49.5 Ophthalmological drugs and preparations	0.000	0.854	0.146
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.854	0.146
T49.3 Emollients, demulcents and protectants	0.000	0.854	0.146
T49.2 Local astringents and local detergents	0.000	0.854	0.146
T49.1 Antipruritics	0.000	0.854	0.146
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.854	0.146
T42.4 Benzodiazepines	0.000	0.864	0.136
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.135	0.865	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.131	0.869	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.874	0.126
T38.9 Other and unspecified hormone antagonists	0.000	0.883	0.117
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.883	0.117
T38.7 Androgens and anabolic congeners	0.000	0.883	0.117
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.883	0.117
T38.5 Other oestrogens and progestogens	0.000	0.883	0.117
T38.4 Oral contraceptives	0.000	0.883	0.117
T38.2 Antithyroid drugs	0.000	0.883	0.117
T38.0 Glucocorticoids and synthetic analogues	0.000	0.883	0.117
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.113	0.887	0.000
T86 Failure and rejection of transplanted organs and tissues	0.111	0.889	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.891	0.109
T88 Other complications of surgical and medical care, not elsewhere classified	0.106	0.894	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.099	0.901	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.098	0.902	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.097	0.903	0.000
T82.3 Mechanical complication of other vascular grafts	0.096	0.904	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.094	0.906	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.094	0.906	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.093	0.907	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.909	0.090
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.089	0.911	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.087	0.913	0.000
T86.4 Liver transplant failure and rejection	0.085	0.915	0.000
T87 Complications peculiar to reattachment and amputation	0.085	0.915	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.084	0.916	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.082	0.918	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.081	0.919	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.080	0.920	0.000
T86.3 Heart-lung transplant failure and rejection	0.080	0.920	0.000
T86.2 Heart transplant failure and rejection	0.080	0.920	0.000
T86.0 Bone-marrow transplant rejection	0.079	0.921	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.078	0.922	0.000
T88.4 Failed or difficult intubation	0.077	0.923	0.000
T88.9 Complication of surgical and medical care, unspecified	0.076	0.923	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.076	0.923	0.000
T88.2 Shock due to anaesthesia	0.076	0.923	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.076	0.923	0.000
T88.0 Infection following immunisation	0.076	0.923	0.000
S80-S89 Injuries to the knee and lower leg	0.076	0.924	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.076	0.924	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.075	0.925	0.000
T86.1 Kidney transplant failure and rejection	0.074	0.925	0.000
S60-S69 Injuries to the wrist and hand	0.074	0.926	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.073	0.927	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.073	0.927	0.000
S80 Superficial injury of lower leg	0.072	0.928	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.070	0.930	0.000
S70-S79 Injuries to the hip and thigh	0.070	0.930	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.070	0.930	0.000
S69 Other and unspecified injuries of wrist and hand	0.070	0.930	0.000
S20-S29 Injuries to the thorax	0.069	0.931	0.000
S90-S99 Injuries to the ankle and foot	0.068	0.932	0.000
S64 Injury of nerves at wrist and hand level	0.068	0.932	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.067	0.933	0.000
S69.9 Unspecified injury of wrist and hand	0.067	0.933	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.067	0.933	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.066	0.934	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.066	0.934	0.000
T85.2 Mechanical complication of intraocular lens	0.066	0.934	0.000
T00-T07 Injuries involving multiple body regions	0.066	0.934	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.065	0.934	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.065	0.935	0.000
S68 Traumatic amputation of wrist and hand	0.065	0.935	0.000
S60 Superficial injury of wrist and hand	0.065	0.935	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.065	0.935	0.000
S80.9 Superficial injury of lower leg, unspecified	0.065	0.935	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.064	0.936	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.064	0.936	0.000
S22.20 Fracture of sternum (closed)	0.064	0.936	0.000
S22.2 Fracture of sternum	0.064	0.936	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.063	0.937	0.000
T87.4 Infection of amputation stump	0.062	0.938	0.000
T87.5 Necrosis of amputation stump	0.061	0.939	0.000
T87.3 Neuroma of amputation stump	0.061	0.939	0.000
T87.2 Complications of other reattached body part	0.061	0.939	0.000
T87.1 Complications of reattached (part of) lower extremity	0.061	0.939	0.000
T87.0 Complications of reattached (part of) upper extremity	0.061	0.939	0.000
S86 Injury of muscle and tendon at lower leg level	0.061	0.939	0.000
S83.3 Tear of articular cartilage of knee, current	0.060	0.940	0.000
S92 Fracture of foot, except ankle	0.060	0.940	0.000
S83.2 Tear of meniscus, current	0.060	0.940	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.059	0.941	0.000
T82.1 Mechanical complication of cardiac electronic device	0.059	0.941	0.000
S64.3 Injury of digital nerve of thumb	0.059	0.941	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.059	0.941	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.059	0.941	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.059	0.941	0.000
S79 Other and unspecified injuries of hip and thigh	0.059	0.941	0.000
S80.0 Contusion of knee	0.058	0.942	0.000
S72 Fracture of femur	0.058	0.942	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.057	0.943	0.000
T23 Burn and corrosion of wrist and hand	0.057	0.943	0.000
T88.5 Other complications of anaesthesia	0.057	0.943	0.000
S22.1 Multiple fractures of thoracic spine	0.057	0.943	0.000
S67 Crushing injury of wrist and hand	0.057	0.943	0.000
S64.1 Injury of median nerve at wrist and hand level	0.057	0.943	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.056	0.943	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.056	0.944	0.000
T33-T35 Frostbite	0.056	0.944	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.056	0.944	0.000
S20 Superficial injury of thorax	0.056	0.944	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.056	0.944	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.055	0.945	0.000
S64.4 Injury of digital nerve of other finger	0.055	0.945	0.000
S88 Traumatic amputation of lower leg	0.055	0.945	0.000
S87 Crushing injury of lower leg	0.055	0.945	0.000
S85 Injury of blood vessels at lower leg level	0.055	0.945	0.000
S84 Injury of nerves at lower leg level	0.055	0.945	0.000
S60.8 Other superficial injuries of wrist and hand	0.055	0.945	0.000
S83.7 Injury to multiple structures of knee	0.054	0.945	0.000
S83.1 Dislocation of knee	0.054	0.945	0.000
S83.0 Dislocation of patella	0.054	0.945	0.000
S65 Injury of blood vessels at wrist and hand level	0.054	0.946	0.000
S70 Superficial injury of hip and thigh	0.054	0.946	0.000
S92.0 Fracture of calcaneus	0.054	0.946	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.054	0.946	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.054	0.946	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.053	0.947	0.000
T02 Fractures involving multiple body regions	0.053	0.947	0.000
S93.1 Dislocation of toe(s)	0.053	0.947	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.052	0.947	0.000
S63.0 Dislocation of wrist	0.052	0.948	0.000
S80.7 Multiple superficial injuries of lower leg	0.052	0.948	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.052	0.948	0.000
S90 Superficial injury of ankle and foot	0.052	0.948	0.000
S10-S19 Injuries to the neck	0.052	0.948	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.051	0.948	0.000
T01 Open wounds involving multiple body regions	0.051	0.949	0.000
T25 Burn and corrosion of ankle and foot	0.051	0.949	0.000
S78 Traumatic amputation of hip and thigh	0.050	0.949	0.000
S77 Crushing injury of hip and thigh	0.050	0.949	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.050	0.949	0.000
S75 Injury of blood vessels at hip and thigh level	0.050	0.949	0.000
S74 Injury of nerves at hip and thigh level	0.050	0.949	0.000
S72.1 Pertrochanteric fracture	0.051	0.949	0.000
T00 Superficial injuries involving multiple body regions	0.050	0.949	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.050	0.950	0.000
T80.6 Other serum reactions	0.050	0.950	0.000
T80.5 Anaphylactic shock due to serum	0.050	0.950	0.000
T80.4 Rh incompatibility reaction	0.050	0.950	0.000
T80.3 ABO incompatibility reaction	0.050	0.950	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.050	0.950	0.000
S79.8 Other specified injuries of hip and thigh	0.050	0.950	0.000
S69.8 Other specified injuries of wrist and hand	0.050	0.950	0.000
S69.7 Multiple injuries of wrist and hand	0.050	0.950	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.050	0.950	0.000
S92.00 Fracture of calcaneus (closed)	0.050	0.950	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.050	0.950	0.000
S26 Injury of heart	0.050	0.950	0.000
S25 Injury of blood vessels of thorax	0.050	0.950	0.000
S24 Injury of nerves and spinal cord at thorax level	0.050	0.950	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.050	0.950	0.000
S92.5 Fracture of other toe	0.050	0.950	0.000
S71 Open wound of hip and thigh	0.049	0.950	0.000
S21 Open wound of thorax	0.049	0.951	0.000
S98 Traumatic amputation of ankle and foot	0.049	0.951	0.000
S97 Crushing injury of ankle and foot	0.049	0.951	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.049	0.951	0.000
S95 Injury of blood vessels at ankle and foot level	0.049	0.951	0.000
S94 Injury of nerves at ankle and foot level	0.049	0.951	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.049	0.951	0.000
S64.8 Injury of other nerves at wrist and hand level	0.049	0.951	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.049	0.951	0.000
T66-T78 Other and unspecified effects of external causes	0.049	0.951	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.049	0.951	0.000
S72.2 Subtrochanteric fracture	0.049	0.951	0.000
T20 Burn and corrosion of head and neck	0.048	0.952	0.000
T79-T79 Certain early complications of trauma	0.048	0.952	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.046	0.952	0.002
T23.2 Burn of second degree of wrist and hand	0.047	0.952	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.047	0.952	0.000
T05 Traumatic amputations involving multiple body regions	0.047	0.952	0.000
T04 Crushing injuries involving multiple body regions	0.047	0.952	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.047	0.952	0.000
T07 Unspecified multiple injuries	0.047	0.952	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.047	0.953	0.000
T87.6 Other and unspecified complications of amputation stump	0.047	0.953	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.047	0.953	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.047	0.953	0.000
T21 Burn and corrosion of trunk	0.047	0.953	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.047	0.953	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.047	0.953	0.000
S68.4 Traumatic amputation of hand at wrist level	0.047	0.953	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.047	0.953	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.047	0.953	0.000
S60.2 Contusion of other parts of wrist and hand	0.047	0.953	0.000
S60.1 Contusion of finger(s) with damage to nail	0.047	0.953	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.047	0.953	0.000
T23.3 Burn of third degree of wrist and hand	0.047	0.953	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.046	0.953	0.000
S22.9 Fracture of bony thorax, part unspecified	0.046	0.953	0.000
S22.8 Fracture of other parts of bony thorax	0.046	0.953	0.000
S22.5 Flail chest	0.046	0.953	0.000
S80.8 Other superficial injuries of lower leg	0.046	0.954	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.046	0.954	0.000
S60.0 Contusion of finger(s) without damage to nail	0.046	0.954	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.046	0.954	0.000
S23.4 Sprain and strain of ribs and sternum	0.046	0.954	0.000
S22.21 Fracture of sternum (open)	0.046	0.954	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.046	0.954	0.000
S72.10 Pertrochanteric fracture (closed)	0.045	0.955	0.000
T31 Burns classified according to extent of body surface involved	0.045	0.955	0.000
S92.7 Multiple fractures of foot	0.045	0.955	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.045	0.955	0.000
S65.1 Injury of radial artery at wrist and hand level	0.045	0.955	0.000
S20.3 Other superficial injuries of front wall of thorax	0.045	0.955	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.045	0.955	0.000
S91 Open wound of ankle and foot	0.045	0.955	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.044	0.955	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.044	0.956	0.000
S20.4 Other superficial injuries of back wall of thorax	0.044	0.956	0.000
S86.0 Injury of Achilles tendon	0.044	0.956	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.044	0.956	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.044	0.956	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.044	0.956	0.000
S92.1 Fracture of talus	0.043	0.956	0.000
S92.9 Fracture of foot, unspecified	0.043	0.957	0.000
S63.1 Dislocation finger	0.043	0.957	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.043	0.957	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.043	0.957	0.000
S63.2 Multiple dislocations of fingers	0.043	0.957	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.043	0.957	0.000
S79.9 Unspecified injury of hip and thigh	0.043	0.957	0.000
S92.4 Fracture of great toe	0.042	0.957	0.000
S50-S59 Injuries to the elbow and forearm	0.043	0.957	0.000
T32 Corrosions classified according to extent of body surface involved	0.042	0.958	0.000
T30 Burn and corrosion, body region unspecified	0.042	0.958	0.000
T29 Burns and corrosions of multiple body regions	0.042	0.958	0.000
S93.4 Sprain and strain of ankle	0.042	0.958	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.042	0.958	0.000
S93.5 Sprain and strain of toe(s)	0.042	0.958	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.042	0.958	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.042	0.958	0.000
S79.7 Multiple injuries of hip and thigh	0.042	0.958	0.000
S29 Other and unspecified injuries of thorax	0.042	0.958	0.000
S72.20 Subtrochanteric fracture (closed)	0.042	0.958	0.000
S22.3 Fracture of rib	0.042	0.958	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.042	0.958	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.042	0.958	0.000
S72.9 Fracture of femur, part unspecified	0.042	0.958	0.000
S72.8 Fractures of other parts of femur	0.042	0.958	0.000
S72.7 Multiple fractures of femur	0.042	0.958	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.041	0.959	0.000
S90.0 Contusion of ankle	0.041	0.959	0.000
S20.2 Contusion of thorax	0.041	0.959	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.041	0.959	0.000
T23.7 Corrosion of third degree of wrist and hand	0.041	0.959	0.000
T23.6 Corrosion of second degree of wrist and hand	0.041	0.959	0.000
T23.5 Corrosion of first degree of wrist and hand	0.041	0.959	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.041	0.959	0.000
T23.1 Burn of first degree of wrist and hand	0.041	0.959	0.000
S81 Open wound of lower leg	0.041	0.959	0.000
T18 Foreign body in alimentary tract	0.041	0.959	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.041	0.959	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.041	0.959	0.000
S20.1 Other and unspecified superficial injuries of breast	0.041	0.959	0.000
S63.5 Sprain and strain of wrist	0.041	0.959	0.000
S72.4 Fracture of lower end of femur	0.041	0.959	0.000
T02.5 Fractures involving multiple regions of both lower limbs	0.040	0.959	0.000
T28 Burn and corrosion of other internal organs	0.040	0.959	0.000
T27 Burn and corrosion of respiratory tract	0.040	0.959	0.000
T26 Burn and corrosion confined to eye and adnexa	0.040	0.959	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.040	0.959	0.000
T34 Frostbite with tissue necrosis	0.040	0.959	0.000
T33 Superficial frostbite	0.040	0.959	0.000
S72.3 Fracture of shaft of femur	0.040	0.960	0.000
S20.7 Multiple superficial injuries of thorax	0.040	0.960	0.000
S20.0 Contusion of breast	0.040	0.960	0.000
S92.51 Fracture of other toe (open)	0.040	0.960	0.000
S92.3 Fracture of metatarsal bone	0.040	0.960	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.040	0.960	0.000
S23.3 Sprain and strain of thoracic spine	0.040	0.960	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.040	0.960	0.000
S23.1 Dislocation of thoracic vertebra	0.040	0.960	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.040	0.960	0.000
S93.0 Dislocation of ankle joint	0.040	0.960	0.000
S19 Other and unspecified injuries of neck	0.040	0.960	0.000
S73.0 Dislocation of hip	0.040	0.960	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.040	0.960	0.000
T19 Foreign body in genito-urinary tract	0.040	0.960	0.000
T15 Foreign body on external eye	0.040	0.960	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.039	0.960	0.000
S84.8 Injury of other nerves at lower leg level	0.039	0.960	0.000
S84.7 Injury of multiple nerves at lower leg level	0.039	0.960	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.039	0.960	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.039	0.960	0.000
S84.0 Injury of tibial nerve at lower leg level	0.039	0.960	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.039	0.960	0.000
S85.8 Injury of other blood vessels at lower leg level	0.039	0.960	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.039	0.960	0.000
S85.5 Injury of popliteal vein	0.039	0.960	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.039	0.960	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.039	0.960	0.000
S85.2 Injury of peroneal artery	0.039	0.960	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.039	0.960	0.000
S85.0 Injury of popliteal artery	0.039	0.960	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.039	0.960	0.000
S87.0 Crushing injury of knee	0.039	0.960	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.039	0.960	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.039	0.960	0.000
S88.0 Traumatic amputation at knee level	0.039	0.960	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.039	0.961	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.039	0.961	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.039	0.961	0.000
S65.4 Injury of blood vessel(s) of thumb	0.039	0.961	0.000
S65.3 Injury of deep palmar arch	0.039	0.961	0.000
S65.2 Injury of superficial palmar arch	0.039	0.961	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.039	0.961	0.000
S92.01 Fracture of calcaneus (open)	0.039	0.961	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.039	0.961	0.000
T25.2 Burn of second degree of ankle and foot	0.039	0.961	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.039	0.961	0.000
T17 Foreign body in respiratory tract	0.039	0.961	0.000
S92.50 Fracture of other toe (closed)	0.038	0.961	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.038	0.961	0.000
T02.9 Multiple fractures, unspecified	0.038	0.962	0.000
T02.8 Fractures involving other combinations of body regions	0.038	0.962	0.000
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.038	0.962	0.000
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.038	0.962	0.000
T02.3 Fractures involving multiple regions of one lower limb	0.038	0.962	0.000
T02.2 Fractures involving multiple regions of one upper limb	0.038	0.962	0.000
T02.1 Fractures involving thorax with lower back and pelvis	0.038	0.962	0.000
T02.0 Fractures involving head with neck	0.038	0.962	0.000
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.038	0.962	0.000
T63 Toxic effect of contact with venomous animals	0.037	0.962	0.001
T68 Hypothermia	0.038	0.962	0.000
T16 Foreign body in ear	0.038	0.962	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.038	0.962	0.000
S73.1 Sprain and strain of hip	0.038	0.962	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.038	0.962	0.000
S89 Other and unspecified injuries of lower leg	0.037	0.962	0.000
S70.8 Other superficial injuries of hip and thigh	0.037	0.962	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.037	0.962	0.000
S99 Other and unspecified injuries of ankle and foot	0.037	0.962	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.037	0.962	0.000
S90.2 Contusion of toe(s) with damage to nail	0.037	0.962	0.000
S90.1 Contusion of toe(s) without damage to nail	0.037	0.962	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.037	0.963	0.000
S17 Crushing injury of neck	0.037	0.963	0.000
S15 Injury of blood vessels at neck level	0.037	0.963	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations