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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12694681
log Bayes Factor = <0.0001
Chromosome 2   position 226,609,241  (GRCh37) Explore rs12694681 on Ensembl!
Variant rs12694681 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
R21 Rash and other nonspecific skin eruption
0.116 0.884 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.063 0.937 0.000
R23 Other skin changes
0.062 0.938 0.000
R23.8 Other and unspecified skin changes
0.059 0.941 0.000
R23.4 Changes in skin texture
0.053 0.947 0.000
R23.0 Cyanosis
0.047 0.953 0.000
R23.1 Pallor
0.046 0.954 0.000
R23.3 Spontaneous ecchymoses
0.046 0.954 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.039 0.961 0.000
R22.0 Localised swelling, mass and lump, head
0.035 0.965 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.034 0.966 0.000
R23.2 Flushing
0.033 0.966 0.000
R22.2 Localised swelling, mass and lump, trunk
0.033 0.967 0.000
H50.9 Strabismus, unspecified
0.022 0.978 0.000
H50 Other strabismus
0.022 0.978 0.000
Z90.1 Acquired absence of breast(s)
0.021 0.979 0.000
H52.0 Hypermetropia
0.021 0.979 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.021 0.979 0.000
H50.1 Divergent concomitant strabismus
0.021 0.979 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.020 0.980 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.019 0.981 0.000
H50.2 Vertical strabismus
0.018 0.982 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.018 0.982 0.000
H50.5 Heterophoria
0.018 0.982 0.000
M06.9 Rheumatoid arthritis, unspecified
0.018 0.982 0.000
H50.4 Other and unspecified heterotropia
0.017 0.983 0.000
H50.8 Other specified strabismus
0.017 0.983 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.016 0.984 0.000
H52 Disorders of refraction and accommodation
0.016 0.984 0.000
H50.6 Mechanical strabismus
0.016 0.984 0.000
H50.3 Intermittent heterotropia
0.016 0.984 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.014 0.986 0.000
M06 Other rheumatoid arthritis
0.014 0.986 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.013 0.986 0.000
H52.4 Presbyopia
0.013 0.987 0.000
M06.4 Inflammatory polyarthropathy
0.013 0.987 0.000
M06.0 Seronegative rheumatoid arthritis
0.013 0.987 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.013 0.987 0.000
H51 Other disorders of binocular movement
0.012 0.987 0.000
R22.1 Localised swelling, mass and lump, neck
0.012 0.988 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.012 0.988 0.000
H52.6 Other disorders of refraction
0.012 0.988 0.000
H52.5 Disorders of accommodation
0.012 0.988 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.012 0.988 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.012 0.988 0.000
H52.7 Disorder of refraction, unspecified
0.011 0.988 0.000
H52.3 Anisometropia and aniseikonia
0.012 0.988 0.000
J98.4 Other disorders of lung
0.012 0.988 0.000
R20 Disturbances of skin sensation
0.011 0.989 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.011 0.989 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.011 0.989 0.000
M06.2 Rheumatoid bursitis
0.010 0.989 0.000
M06.1 Adult-onset Still's disease
0.010 0.989 0.000
H49 Paralytic strabismus
0.011 0.989 0.000
W25.9 Unspecified place
0.000 0.989 0.011
M06.8 Other specified rheumatoid arthritis
0.010 0.989 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.010 0.990 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.010 0.990 0.000
H52.2 Astigmatism
0.010 0.990 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.010 0.990 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.010 0.990 0.000
H51.2 Internuclear ophthalmoplegia
0.010 0.990 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.009 0.990 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.009 0.990 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.009 0.990 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.009 0.990 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.009 0.990 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.009 0.990 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.009 0.990 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.009 0.990 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.009 0.990 0.000
M81 Osteoporosis without pathological fracture
0.009 0.991 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.009 0.991 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.009 0.991 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.009 0.991 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.009 0.991 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.009 0.991 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.009 0.991 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.009 0.991 0.000
H51.9 Disorder of binocular movement, unspecified
0.009 0.991 0.000
H51.8 Other specified disorders of binocular movement
0.009 0.991 0.000
H51.1 Convergence insufficiency and excess
0.009 0.991 0.000
H51.0 Palsy of conjugate gaze
0.009 0.991 0.000
M62.8 Other specified disorders of muscle
0.009 0.991 0.000
H49.9 Paralytic strabismus, unspecified
0.009 0.991 0.000
M81.98 Osteoporosis, unspecified (Other)
0.009 0.991 0.000
H49.0 Third [oculomotor] nerve palsy
0.009 0.991 0.000
R20.1 Hypoaesthesia of skin
0.009 0.991 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.008 0.991 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.009 0.991 0.000
M81.4 Drug-induced osteoporosis
0.008 0.991 0.000
M81.2 Osteoporosis of disuse
0.008 0.991 0.000
H90.3 Sensorineural hearing loss, bilateral
0.008 0.992 0.000
J98 Other respiratory disorders
0.008 0.992 0.000
M81.9 Osteoporosis, unspecified
0.008 0.992 0.000
M62 Other disorders of muscle
0.008 0.992 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.008 0.992 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.008 0.992 0.000
H49.4 Progressive external ophthalmoplegia
0.008 0.992 0.000
J98.9 Respiratory disorder, unspecified
0.008 0.992 0.000
M62.88 Other specified disorders of muscle (Other)
0.008 0.992 0.000
M06.3 Rheumatoid nodule
0.008 0.992 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.008 0.992 0.000
M06.18 Adult-onset Still's disease (Other)
0.008 0.992 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.008 0.992 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.008 0.992 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.008 0.992 0.000
M06.14 Adult-onset Still's disease (Hand)
0.008 0.992 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.008 0.992 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.008 0.992 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.008 0.992 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.008 0.992 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.008 0.992 0.000
M06.28 Rheumatoid bursitis (Other)
0.008 0.992 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.008 0.992 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.008 0.992 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.008 0.992 0.000
M06.24 Rheumatoid bursitis (Hand)
0.008 0.992 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.008 0.992 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.008 0.992 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.008 0.992 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.008 0.992 0.000
H49.8 Other paralytic strabismus
0.008 0.992 0.000
H49.3 Total (external) ophthalmoplegia
0.008 0.992 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.008 0.992 0.000
M62.84 Other specified disorders of muscle (Hand)
0.008 0.992 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.008 0.992 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.008 0.992 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.008 0.992 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.008 0.992 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.008 0.992 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.008 0.992 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.008 0.992 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.008 0.992 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.008 0.992 0.000
R20.0 Anaesthesia of skin
0.008 0.992 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.008 0.992 0.000
J98.2 Interstitial emphysema
0.008 0.992 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.007 0.992 0.000
M81.0 Postmenopausal osteoporosis
0.008 0.992 0.000
M05-M14 Inflammatory polyarthropathies
0.008 0.992 0.000
M81.1 Postoophorectomy osteoporosis
0.007 0.992 0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.007 0.993 0.000
Z80.3 Family history of malignant neoplasm of breast
0.007 0.993 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.007 0.993 0.000
M62.6 Muscle strain
0.007 0.993 0.000
R20.3 Hyperaesthesia
0.007 0.993 0.000
C71.9 Brain, unspecified
0.007 0.993 0.000
M81.8 Other osteoporosis
0.007 0.993 0.000
M81.6 Localised osteoporosis [Lequesne]
0.007 0.993 0.000
M81.5 Idiopathic osteoporosis
0.007 0.993 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.007 0.993 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.007 0.993 0.000
M80-M85 Disorders of bone density and structure
0.007 0.993 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.007 0.993 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.007 0.993 0.000
M62.0 Diastasis of muscle
0.007 0.993 0.000
M85.0 Fibrous dysplasia (monostotic)
0.007 0.993 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.006 0.993 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.007 0.993 0.000
M85 Other disorders of bone density and structure
0.007 0.993 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.006 0.993 0.000
M65.8 Other synovitis and tenosynovitis
0.007 0.993 0.000
M05 Seropositive rheumatoid arthritis
0.006 0.993 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.006 0.994 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.006 0.994 0.000
M62.9 Disorder of muscle, unspecified
0.006 0.994 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.006 0.994 0.000
M81.28 Osteoporosis of disuse (Other)
0.006 0.994 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.006 0.994 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.006 0.994 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.006 0.994 0.000
M81.24 Osteoporosis of disuse (Hand)
0.006 0.994 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.006 0.994 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.006 0.994 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.006 0.994 0.000
M81.48 Drug-induced osteoporosis (Other)
0.006 0.994 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.006 0.994 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.006 0.994 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.006 0.994 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.006 0.994 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.006 0.994 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.006 0.994 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.006 0.994 0.000
J98.8 Other specified respiratory disorders
0.006 0.994 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.006 0.994 0.000
J98.3 Compensatory emphysema
0.006 0.994 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.006 0.994 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.006 0.994 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.006 0.994 0.000
M62.4 Contracture of muscle
0.006 0.994 0.000
M62.3 Immobility syndrome (paraplegic)
0.006 0.994 0.000
M62.2 Ischaemic infarction of muscle
0.006 0.994 0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.006 0.994 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.006 0.994 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.006 0.994 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.006 0.994 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.006 0.994 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.006 0.994 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.006 0.994 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.006 0.994 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.006 0.994 0.000
M62.65 Muscle strain (Pelvic region and thigh)
0.006 0.994 0.000
E27 Other disorders of adrenal gland
0.006 0.994 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.006 0.994 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.006 0.994 0.000
M60-M63 Disorders of muscles
0.006 0.994 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.006 0.994 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.006 0.994 0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck
0.006 0.994 0.000
A40.9 Streptococcal septicaemia, unspecified
0.000 0.994 0.006
H66.3 Other chronic suppurative otitis media
0.000 0.994 0.006
J98.6 Disorders of diaphragm
0.006 0.994 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.006 0.994 0.000
M06.38 Rheumatoid nodule (Other)
0.006 0.994 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.006 0.994 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.006 0.994 0.000
M06.33 Rheumatoid nodule (Forearm)
0.006 0.994 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.006 0.994 0.000
H49.1 Fourth [trochlear] nerve palsy
0.006 0.994 0.000
E27.8 Other specified disorders of adrenal gland
0.006 0.994 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.006 0.994 0.000
M12 Other specific arthropathies
0.006 0.994 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.006 0.994 0.000
M85.8 Other specified disorders of bone density and structure
0.006 0.994 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.006 0.994 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.006 0.994 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.006 0.994 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.006 0.994 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.006 0.994 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.006 0.994 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.006 0.994 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.006 0.994 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.006 0.994 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.006 0.994 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.006 0.994 0.000
M86 Osteomyelitis
0.006 0.994 0.000
M62.68 Muscle strain (Other)
0.006 0.994 0.000
M62.66 Muscle strain (Lower leg)
0.006 0.994 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.006 0.994 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.006 0.994 0.000
M08 Juvenile arthritis
0.006 0.994 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.006 0.994 0.000
E27.2 Addisonian crisis
0.006 0.994 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.005 0.994 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.005 0.994 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.005 0.994 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.005 0.994 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.005 0.994 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.005 0.994 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.005 0.994 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.005 0.994 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.005 0.994 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.005 0.994 0.000
M83 Adult osteomalacia
0.006 0.994 0.000
E27.9 Disorder of adrenal gland, unspecified
0.006 0.994 0.000
M85.4 Solitary bone cyst
0.006 0.994 0.000
M89.0 Algoneurodystrophy
0.006 0.994 0.000
M07 Psoriatic and enteropathic arthropathies
0.006 0.994 0.000
E27.1 Primary adrenocortical insufficiency
0.006 0.994 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.005 0.994 0.000
M86-M90 Other osteopathies
0.006 0.994 0.000
M62.69 Muscle strain (Site unspecified)
0.005 0.995 0.000
M62.67 Muscle strain (Ankle and foot)
0.005 0.995 0.000
M62.64 Muscle strain (Hand)
0.005 0.995 0.000
M62.63 Muscle strain (Forearm)
0.005 0.995 0.000
M62.62 Muscle strain (Upper arm)
0.005 0.995 0.000
M62.61 Muscle strain (Shoulder region)
0.005 0.995 0.000
M62.60 Muscle strain (Multiple sites)
0.005 0.995 0.000
M89 Other disorders of bone
0.005 0.995 0.000
M14 Arthropathies in other diseases classified elsewhere
0.005 0.995 0.000
M62.08 Diastasis of muscle (Other)
0.005 0.995 0.000
M10 Gout
0.005 0.995 0.000
S13.4 Sprain and strain of cervical spine
0.005 0.995 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.005 0.995 0.000
M81.58 Idiopathic osteoporosis (Other)
0.005 0.995 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.005 0.995 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.005 0.995 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.005 0.995 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.005 0.995 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.005 0.995 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.005 0.995 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.005 0.995 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.005 0.995 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.005 0.995 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.005 0.995 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.005 0.995 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.005 0.995 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.005 0.995 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.005 0.995 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.005 0.995 0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.005 0.995 0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.005 0.995 0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.005 0.995 0.000
M81.89 Other osteoporosis (Site unspecified)
0.005 0.995 0.000
M81.88 Other osteoporosis (Other)
0.005 0.995 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.005 0.995 0.000
M81.86 Other osteoporosis (Lower leg)
0.005 0.995 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.005 0.995 0.000
M81.84 Other osteoporosis (Hand)
0.005 0.995 0.000
M81.83 Other osteoporosis (Forearm)
0.005 0.995 0.000
M81.82 Other osteoporosis (Upper arm)
0.005 0.995 0.000
M81.81 Other osteoporosis (Shoulder region)
0.005 0.995 0.000
M81.80 Other osteoporosis (Multiple sites)
0.005 0.995 0.000
M86.9 Osteomyelitis, unspecified
0.005 0.995 0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)
0.005 0.995 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.005 0.995 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.005 0.995 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.005 0.995 0.000
M05.8 Other seropositive rheumatoid arthritis
0.005 0.995 0.000
M11 Other crystal arthropathies
0.005 0.995 0.000
J98.1 Pulmonary collapse
0.005 0.995 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.005 0.995 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.005 0.995 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.005 0.995 0.000
H50.0 Convergent concomitant strabismus
0.005 0.995 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.005 0.995 0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.005 0.995 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.005 0.995 0.000
H49.2 Sixth [abducent] nerve palsy
0.005 0.995 0.000
W25 Contact with sharp glass
0.000 0.995 0.005
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.005 0.995 0.000
M05.1 Rheumatoid lung disease
0.005 0.995 0.000
M62.09 Diastasis of muscle (Site unspecified)
0.005 0.995 0.000
M62.07 Diastasis of muscle (Ankle and foot)
0.005 0.995 0.000
M62.06 Diastasis of muscle (Lower leg)
0.005 0.995 0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)
0.005 0.995 0.000
M62.04 Diastasis of muscle (Hand)
0.005 0.995 0.000
M62.03 Diastasis of muscle (Forearm)
0.005 0.995 0.000
M62.02 Diastasis of muscle (Upper arm)
0.005 0.995 0.000
M62.01 Diastasis of muscle (Shoulder region)
0.005 0.995 0.000
M62.00 Diastasis of muscle (Multiple sites)
0.005 0.995 0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)
0.005 0.995 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.005 0.995 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.005 0.995 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.005 0.995 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.005 0.995 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.005 0.995 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.005 0.995 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.005 0.995 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.005 0.995 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.005 0.995 0.000
M86.8 Other osteomyelitis
0.005 0.995 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.005 0.995 0.000
M85.5 Aneurysmal bone cyst
0.005 0.995 0.000
M85.3 Osteitis condensans
0.005 0.995 0.000
M85.1 Skeletal fluorosis
0.005 0.995 0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)
0.005 0.995 0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)
0.005 0.995 0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)
0.005 0.995 0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)
0.005 0.995 0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)
0.005 0.995 0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)
0.005 0.995 0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)
0.005 0.995 0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)
0.005 0.995 0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)
0.005 0.995 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.005 0.995 0.000
Q60.0 Renal agenesis, unilateral
0.005 0.995 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.005 0.995 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.005 0.995 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.005 0.995 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.005 0.995 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.005 0.995 0.000
M66 Spontaneous rupture of synovium and tendon
0.005 0.995 0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)
0.005 0.995 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.005 0.995 0.000
M65-M68 Disorders of synovium and tendon
0.005 0.995 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.005 0.995 0.000
M05.2 Rheumatoid vasculitis
0.005 0.995 0.000
M05.0 Felty's syndrome
0.005 0.995 0.000
M86.6 Other chronic osteomyelitis
0.005 0.995 0.000
M89.8 Other specified disorders of bone
0.005 0.995 0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)
0.005 0.995 0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)
0.005 0.995 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.005 0.995 0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)
0.005 0.995 0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)
0.005 0.995 0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)
0.005 0.995 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.005 0.995 0.000
M62.98 Disorder of muscle, unspecified (Other)
0.005 0.995 0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)
0.005 0.995 0.000
M62.96 Disorder of muscle, unspecified (Lower leg)
0.005 0.995 0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M62.94 Disorder of muscle, unspecified (Hand)
0.005 0.995 0.000
M62.93 Disorder of muscle, unspecified (Forearm)
0.005 0.995 0.000
M62.92 Disorder of muscle, unspecified (Upper arm)
0.005 0.995 0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)
0.005 0.995 0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)
0.005 0.995 0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.005 0.995 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.005 0.995 0.000
Z71.3 Dietary counselling and surveillance
0.000 0.995 0.005
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.005 0.995 0.000
M00-M03 Infectious arthropathies
0.005 0.995 0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)
0.005 0.995 0.000
M62.28 Ischaemic infarction of muscle (Other)
0.005 0.995 0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)
0.005 0.995 0.000
M62.26 Ischaemic infarction of muscle (Lower leg)
0.005 0.995 0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)
0.005 0.995 0.000
M62.24 Ischaemic infarction of muscle (Hand)
0.005 0.995 0.000
M62.23 Ischaemic infarction of muscle (Forearm)
0.005 0.995 0.000
M62.22 Ischaemic infarction of muscle (Upper arm)
0.005 0.995 0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)
0.005 0.995 0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)
0.005 0.995 0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)
0.005 0.995 0.000
M62.38 Immobility syndrome (paraplegic) (Other)
0.005 0.995 0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)
0.005 0.995 0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)
0.005 0.995 0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)
0.005 0.995 0.000
M62.34 Immobility syndrome (paraplegic) (Hand)
0.005 0.995 0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)
0.005 0.995 0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)
0.005 0.995 0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)
0.005 0.995 0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)
0.005 0.995 0.000
M62.49 Contracture of muscle (Site unspecified)
0.005 0.995 0.000
M62.48 Contracture of muscle (Other)
0.005 0.995 0.000
M62.47 Contracture of muscle (Ankle and foot)
0.005 0.995 0.000
M62.46 Contracture of muscle (Lower leg)
0.005 0.995 0.000
M62.45 Contracture of muscle (Pelvic region and thigh)
0.005 0.995 0.000
M62.44 Contracture of muscle (Hand)
0.005 0.995 0.000
M62.43 Contracture of muscle (Forearm)
0.005 0.995 0.000
M62.42 Contracture of muscle (Upper arm)
0.005 0.995 0.000
M62.41 Contracture of muscle (Shoulder region)
0.005 0.995 0.000
M62.40 Contracture of muscle (Multiple sites)
0.005 0.995 0.000
E27.5 Adrenomedullary hyperfunction
0.005 0.995 0.000
E27.0 Other adrenocortical overactivity
0.005 0.995 0.000
M65 Synovitis and tenosynovitis
0.005 0.995 0.000
M83.9 Adult osteomalacia, unspecified
0.005 0.995 0.000
M85.9 Disorder of bone density and structure, unspecified
0.005 0.995 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.005 0.995 0.000
M61 Calcification and ossification of muscle
0.005 0.995 0.000
M82 Osteoporosis in diseases classified elsewhere
0.005 0.995 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.005 0.995 0.000
G81.9 Hemiplegia, unspecified
0.005 0.995 0.000
M12.2 Villonodular synovitis (pigmented)
0.004 0.995 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.004 0.995 0.000
M66.3 Spontaneous rupture of flexor tendons
0.005 0.995 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.005 0.995 0.000
M85.2 Hyperostosis of skull
0.004 0.995 0.000
S13.1 Dislocation of cervical vertebra
0.005 0.995 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.004 0.995 0.000
J18.1 Lobar pneumonia, unspecified
0.005 0.995 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.004 0.995 0.000
M86.87 Other osteomyelitis (Ankle and foot)
0.004 0.995 0.000
M12.5 Traumatic arthropathy
0.004 0.995 0.000
M12.4 Intermittent hydrarthrosis
0.004 0.995 0.000
M12.1 Kaschin-Beck disease
0.004 0.995 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.004 0.995 0.000
M10.90 Gout, unspecified (Multiple sites)
0.005 0.995 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.004 0.995 0.000
M83.1 Senile osteomalacia
0.004 0.995 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.004 0.996 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.004 0.996 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.004 0.996 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.004 0.996 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.004 0.996 0.000
M07.6 Other enteropathic arthropathies
0.004 0.996 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.004 0.996 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.004 0.996 0.000
M66.2 Spontaneous rupture of extensor tendons
0.004 0.996 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.004 0.996 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.004 0.996 0.000
M86.3 Chronic multifocal osteomyelitis
0.004 0.996 0.000
M86.2 Subacute osteomyelitis
0.004 0.996 0.000
M86.1 Other acute osteomyelitis
0.004 0.996 0.000
M86.0 Acute haematogenous osteomyelitis
0.004 0.996 0.000
M89.3 Hypertrophy of bone
0.004 0.996 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.004 0.996 0.000
M08.9 Juvenile arthritis, unspecified
0.004 0.996 0.000
M08.8 Other juvenile arthritis
0.004 0.996 0.000
M08.4 Pauciarticular juvenile arthritis
0.004 0.996 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.004 0.996 0.000
M08.2 Juvenile arthritis with systemic onset
0.004 0.996 0.000
M08.1 Juvenile ankylosing spondylitis
0.004 0.996 0.000
M08.0 Juvenile rheumatoid arthritis
0.004 0.996 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.004 0.996 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.004 0.996 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.004 0.996 0.000
M09.0 Juvenile arthritis in psoriasis
0.004 0.996 0.000
M83.8 Other adult osteomalacia
0.004 0.996 0.000
M83.5 Other drug-induced osteomalacia in adults
0.004 0.996 0.000
M83.4 Aluminum bone disease
0.004 0.996 0.000
M83.3 Adult osteomalacia due to malnutrition
0.004 0.996 0.000
M83.2 Adult osteomalacia due to malabsorption
0.004 0.996 0.000
M83.0 Puerperal osteomalacia
0.004 0.996 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.004 0.996 0.000
M85.49 Solitary bone cyst (Site unspecified)
0.004 0.996 0.000
M85.48 Solitary bone cyst (Other)
0.004 0.996 0.000
M85.46 Solitary bone cyst (Lower leg)
0.004 0.996 0.000
M85.44 Solitary bone cyst (Hand)
0.004 0.996 0.000
M85.43 Solitary bone cyst (Forearm)
0.004 0.996 0.000
M85.42 Solitary bone cyst (Upper arm)
0.004 0.996 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.004 0.996 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.004 0.996 0.000
M89.08 Algoneurodystrophy (Other)
0.004 0.996 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.004 0.996 0.000
M89.03 Algoneurodystrophy (Forearm)
0.004 0.996 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.004 0.996 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.004 0.996 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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