TreeWAS – Variant ID: rs12703441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C77.0 Lymph nodes of head, face and neck	0.000	0.463	0.537
C77.1 Intrathoracic lymph nodes	0.000	0.485	0.515
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.486	0.514
C77.4 Inguinal and lower limb lymph nodes	0.000	0.506	0.494
C77.5 Intrapelvic lymph nodes	0.000	0.578	0.422
C77.8 Lymph nodes of multiple regions	0.000	0.593	0.407
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.915	0.085
C77.9 Lymph node, unspecified	0.000	0.917	0.083
C80 Malignant neoplasm without specification of site	0.000	0.922	0.078
C77.3 Axillary and upper limb lymph nodes	0.000	0.924	0.076
C80.9 Malignant neoplasm, unspecified	0.000	0.925	0.075
F33.1 Recurrent depressive disorder, current episode moderate	0.072	0.928	0.000
F33 Recurrent depressive disorder	0.068	0.932	0.000
F33.9 Recurrent depressive disorder, unspecified	0.060	0.940	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.059	0.941	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.942	0.058
F33.0 Recurrent depressive disorder, current episode mild	0.058	0.942	0.000
F33.8 Other recurrent depressive disorders	0.057	0.943	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.052	0.948	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.050	0.950	0.000
C76.2 Abdomen	0.000	0.953	0.046
C76.3 Pelvis	0.000	0.956	0.044
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.956	0.044
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.958	0.042
C76.7 Other ill-defined sites	0.000	0.958	0.042
C76.5 Lower limb	0.000	0.958	0.042
C76.4 Upper limb	0.000	0.958	0.042
C76.1 Thorax	0.000	0.961	0.038
C77.2 Intra-abdominal lymph nodes	0.000	0.964	0.036
C76.0 Head, face and neck	0.000	0.967	0.033
F30-F39 Mood [affective] disorders	0.020	0.980	0.000
I38 Endocarditis, valve unspecified	0.018	0.982	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.983	0.017
F34 Persistent mood [affective] disorders	0.017	0.983	0.000
F38 Other mood [affective] disorders	0.017	0.983	0.000
F30 Manic episode	0.015	0.985	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.985	0.015
F34.1 Dysthymia	0.014	0.986	0.000
F30.9 Manic episode, unspecified	0.013	0.987	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.987	0.013
F38.8 Other specified mood [affective] disorders	0.013	0.987	0.000
F38.0 Other single mood [affective] disorders	0.013	0.987	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.987	0.013
F34.0 Cyclothymia	0.013	0.987	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.987	0.013
F39 Unspecified mood [affective] disorder	0.013	0.987	0.000
F31 Bipolar affective disorder	0.012	0.988	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.012	0.988	0.000
F34.8 Other persistent mood [affective] disorders	0.012	0.988	0.000
F38.1 Other recurrent mood [affective] disorders	0.012	0.988	0.000
F30.1 Mania without psychotic symptoms	0.012	0.988	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.988	0.012
F30.8 Other manic episodes	0.011	0.989	0.000
F30.2 Mania with psychotic symptoms	0.011	0.989	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.989	0.011
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.011	0.989	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
F31.7 Bipolar affective disorder, currently in remission	0.010	0.990	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.010	0.990	0.000
K13.0 Diseases of lips	0.000	0.990	0.010
F31.6 Bipolar affective disorder, current episode mixed	0.010	0.990	0.000
F31.8 Other bipolar affective disorders	0.010	0.990	0.000
O32.1 Maternal care for breech presentation	0.000	0.991	0.009
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.009	0.991	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.992	0.008
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.992	0.008
F32 Depressive episode	0.008	0.992	0.000
F32.0 Mild depressive episode	0.008	0.992	0.000
F30.0 Hypomania	0.007	0.993	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.993	0.007
O32.3 Maternal care for face, brow and chin presentation	0.000	0.993	0.007
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.993	0.007
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.006	0.994	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.001	0.994	0.006
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.994	0.006
O32.0 Maternal care for unstable lie	0.000	0.994	0.006
N60.3 Fibrosclerosis of breast	0.006	0.994	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.006	0.994	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.006	0.994	0.000
F32.1 Moderate depressive episode	0.006	0.994	0.000
O32.6 Maternal care for compound presentation	0.000	0.994	0.005
F32.2 Severe depressive episode without psychotic symptoms	0.005	0.995	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.005	0.995	0.000
L53.9 Erythematous condition, unspecified	0.005	0.995	0.000
O32.2 Maternal care for transverse and oblique lie	0.000	0.995	0.005
F31.9 Bipolar affective disorder, unspecified	0.005	0.995	0.000
Z45.8 Adjustment and management of other implanted devices	0.005	0.995	0.000
F32.8 Other depressive episodes	0.005	0.995	0.000
O20.0 Threatened abortion	0.005	0.995	0.000
S61.7 Multiple open wounds of wrist and hand	0.005	0.995	0.000
O32.4 Maternal care for high head at term	0.000	0.995	0.005
T42.4 Benzodiazepines	0.005	0.995	0.000
K90.0 Coeliac disease	0.000	0.995	0.005
O70.2 Third degree perineal laceration during delivery	0.000	0.995	0.005
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.004	0.996	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.996	0.004
M79.19 Myalgia (Site unspecified)	0.000	0.996	0.004
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
M79.1 Myalgia	0.000	0.996	0.004
M79.16 Myalgia (Lower leg)	0.000	0.996	0.004
Z40.8 Other prophylactic surgery	0.000	0.996	0.004
C09.9 Tonsil, unspecified	0.000	0.996	0.004
M79.18 Myalgia (Other)	0.000	0.996	0.004
F32.3 Severe depressive episode with psychotic symptoms	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.997	0.003
Z94.0 Kidney transplant status	0.000	0.997	0.003
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.997	0.003
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.997	0.003
M79.14 Myalgia (Hand)	0.000	0.997	0.003
M79.13 Myalgia (Forearm)	0.000	0.997	0.003
M79.12 Myalgia (Upper arm)	0.000	0.997	0.003
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.997	0.003
D04.7 Skin of lower limb, including hip	0.003	0.997	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.997	0.003
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.997	0.003
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
W19.9 Unspecified place	0.003	0.997	0.000
K90 Intestinal malabsorption	0.000	0.997	0.003
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.997	0.003
Z40 Prophylactic surgery	0.000	0.997	0.003
L53 Other erythematous conditions	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.997	0.003
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.997	0.003
T36.3 Macrolides	0.003	0.997	0.000
N86 Erosion and ectropion of cervix uteri	0.003	0.997	0.000
H27.0 Aphakia	0.003	0.997	0.000
L53.8 Other specified erythematous conditions	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.998	0.002
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.998	0.002
K90.3 Pancreatic steatorrhoea	0.000	0.998	0.002
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.998	0.002
K90.1 Tropical sprue	0.000	0.998	0.002
K90.8 Other intestinal malabsorption	0.000	0.998	0.002
B50.9 Plasmodium falciparum malaria, unspecified	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
L53.3 Other chronic figurate erythema	0.002	0.998	0.000
L53.2 Erythema marginatum	0.002	0.998	0.000
L53.1 Erythema annulare centrifugum	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
R09.1 Pleurisy	0.000	0.998	0.002
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.998	0.002
C09 Malignant neoplasm of tonsil	0.000	0.998	0.002
G90.2 Horner's syndrome	0.002	0.998	0.000
Z40.9 Prophylactic surgery, unspecified	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
L53.0 Toxic erythema	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
Y60.4 During endoscopic examination	0.002	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.000	0.998	0.002
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.002	0.998	0.000
L73.9 Follicular disorder, unspecified	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
K13.5 Oral submucous fibrosis	0.000	0.998	0.002
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
C09.8 Overlapping lesion of tonsil	0.000	0.998	0.002
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.998	0.002
C09.0 Tonsillar fossa	0.000	0.998	0.002
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.002	0.998	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.998	0.002
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.998	0.002
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
D04.5 Skin of trunk	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y60.8 During other surgical and medical care	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
G40.9 Epilepsy, unspecified	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
C02.4 Lingual tonsil	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
T42.1 Iminostilbenes	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.998	0.002
O22.0 Varicose veins of lower extremity in pregnancy	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
O86.8 Other specified puerperal infections	0.002	0.998	0.000
Y61.0 During surgical operation	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
D04.9 Skin, unspecified	0.001	0.998	0.000
S32.5 Fracture of pubis	0.000	0.998	0.001
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Y65 Other misadventures during surgical and medical care	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
G90.3 Multisystem degeneration	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.002	0.998	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.998	0.001
K13.3 Hairy leukoplakia	0.000	0.998	0.001
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
B50 Plasmodium falciparum malaria	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.001	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.998	0.001
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
G90.4 Autonomic dysreflexia	0.001	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.001	0.998	0.000
O21.2 Late vomiting of pregnancy	0.001	0.998	0.000
S01.9 Open wound of head, part unspecified	0.000	0.998	0.002
X23.9 Unspecified place	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.001	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
Y65.4 Failure to introduce or to remove other tube or instrument	0.001	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
D23.9 Skin, unspecified	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
O22.4 Haemorrhoids in pregnancy	0.001	0.998	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.001	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.001	0.998	0.000
M66.0 Rupture of popliteal cyst	0.001	0.998	0.000
Y60.9 During unspecified surgical and medical care	0.001	0.998	0.000
Y60.7 During administration of enema	0.001	0.998	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.001	0.998	0.000
Y60.5 During heart catheterisation	0.001	0.998	0.000
Y60.3 During injection or immunisation	0.001	0.998	0.000
Y60.2 During kidney dialysis or other perfusion	0.001	0.998	0.000
Y60.1 During infusion or transfusion	0.001	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.998	0.000
K38 Other diseases of appendix	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.001	0.999	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.999	0.001
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.999	0.001
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
B37.1 Pulmonary candidiasis	0.001	0.999	0.000
I47.2 Ventricular tachycardia	0.001	0.999	0.000
R25.1 Tremor, unspecified	0.000	0.999	0.001
O86 Other puerperal infections	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
C78.7 Secondary malignant neoplasm of liver	0.000	0.999	0.001
K38.9 Disease of appendix, unspecified	0.001	0.999	0.000
N36.8 Other specified disorders of urethra	0.001	0.999	0.000
N42.0 Calculus of prostate	0.001	0.999	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M41 Scoliosis	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.999	0.001
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
K13.1 Cheek and lip biting	0.000	0.999	0.001
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
Y65.5 Performance of inappropriate operation	0.001	0.999	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.001	0.999	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.001	0.999	0.000
Y65.1 Wrong fluid used in infusion	0.001	0.999	0.000
Y65.0 Mismatched blood used in transfusion	0.001	0.999	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.001	0.999	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.999	0.001
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.999	0.001
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.999	0.001
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.999	0.001
B50.8 Other severe and complicated Plasmodium falciparum malaria	0.001	0.999	0.000
B50.0 Plasmodium falciparum malaria with cerebral complications	0.001	0.999	0.000
C04.9 Floor of mouth, unspecified	0.000	0.999	0.001
N08.5 Glomerular disorders in systemic connective tissue disorders	0.000	0.999	0.001
O22.9 Venous complication in pregnancy, unspecified	0.001	0.999	0.000
O22.8 Other venous complications in pregnancy	0.001	0.999	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.999	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.999	0.000
O22.1 Genital varices in pregnancy	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
C90.0 Multiple myeloma	0.001	0.999	0.000
K38.1 Appendicular concretions	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.000	0.999	0.001
Q18.8 Other specified congenital malformations of face and neck	0.000	0.999	0.001
Q18.7 Microcheilia	0.000	0.999	0.001
Q18.6 Macrocheilia	0.000	0.999	0.001
Q18.5 Microstomia	0.000	0.999	0.001
Q18.4 Macrostomia	0.000	0.999	0.001
Q18.3 Webbing of neck	0.000	0.999	0.001
Q18.2 Other branchial cleft malformations	0.000	0.999	0.001
T47.2 Stimulant laxatives	0.001	0.999	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
C18.2 Ascending colon	0.001	0.999	0.000
K38.0 Hyperplasia of appendix	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D39.1 Ovary	0.001	0.999	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.001	0.999	0.000
K38.3 Fistula of appendix	0.001	0.999	0.000
K38.2 Diverticulum of appendix	0.001	0.999	0.000
M40.5 Lordosis, unspecified	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.999	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
Y61.9 During unspecified surgical and medical care	0.001	0.999	0.000
Y61.8 During other surgical and medical care	0.001	0.999	0.000
Y61.7 During removal of catheter or packing	0.001	0.999	0.000
Y61.6 During aspiration, puncture and other catheterisation	0.001	0.999	0.000
Y61.5 During heart catheterisation	0.001	0.999	0.000
Y61.4 During endoscopic examination	0.001	0.999	0.000
Y61.3 During injection or immunisation	0.001	0.999	0.000
Y61.2 During kidney dialysis or other perfusion	0.001	0.999	0.000
Y61.1 During infusion or transfusion	0.001	0.999	0.000
Y76.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y76.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Z49.2 Other dialysis	0.000	0.999	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.999	0.001
O92 Other disorders of breast and lactation associated with childbirth	0.001	0.999	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.001	0.999	0.000
M66.08 Rupture of popliteal cyst-Other	0.001	0.999	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.001	0.999	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.001	0.999	0.000
M66.04 Rupture of popliteal cyst-Hand	0.001	0.999	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.001	0.999	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.001	0.999	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.001	0.999	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.999	0.001
H18.1 Bullous keratopathy	0.001	0.999	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
T41.5 Therapeutic gases	0.001	0.999	0.000
T41.4 Anaesthetic, unspecified	0.001	0.999	0.000
T41.3 Local anaesthetics	0.001	0.999	0.000
T41.1 Intravenous anaesthetics	0.001	0.999	0.000
T41.0 Inhaled anaesthetics	0.001	0.999	0.000
T47.4 Other laxatives	0.001	0.999	0.000
O29 Complications of anaesthesia during pregnancy	0.001	0.999	0.000
O25 Malnutrition in pregnancy	0.001	0.999	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.999	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.999	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.999	0.000
O86.4 Pyrexia of unknown origin following delivery	0.001	0.999	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.000	0.999	0.001
M41.4 Neuromuscular scoliosis	0.001	0.999	0.000
M41.3 Thoracogenic scoliosis	0.001	0.999	0.000
M41.2 Other idiopathic scoliosis	0.001	0.999	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.999	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.999	0.000
O86.3 Other genito-urinary tract infections following delivery	0.001	0.999	0.000
H17 Corneal scars and opacities	0.001	0.999	0.000
O21 Excessive vomiting in pregnancy	0.001	0.999	0.000
M40.52 Lordosis, unspecified (Cervical region)	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.999	0.001
M66.4 Spontaneous rupture of other tendons	0.001	0.999	0.000
R23.1 Pallor	0.001	0.999	0.000
Y64 Contaminated medical or biological substances	0.001	0.999	0.000
Y63 Failure in dosage during surgical and medical care	0.001	0.999	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.001	0.999	0.000
Y69 Unspecified misadventure during surgical and medical care	0.001	0.999	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.999	0.001
B08.1 Molluscum contagiosum	0.000	0.999	0.001
D04.4 Skin of scalp and neck	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.999	0.001
H18.9 Disorder of cornea, unspecified	0.001	0.999	0.000
M41.5 Other secondary scoliosis	0.001	0.999	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
Y66 Nonadministration of surgical and medical care	0.001	0.999	0.000
Z83 Family history of other specific disorders	0.000	0.999	0.001
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.999	0.000
M40.59 Lordosis, unspecified (Site unspecified)	0.001	0.999	0.000
M40.58 Lordosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M40.57 Lordosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M40.55 Lordosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M40.54 Lordosis, unspecified (Thoracic region)	0.001	0.999	0.000
M40.53 Lordosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M40.51 Lordosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M40.50 Lordosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.999	0.000
C02.8 Overlapping lesion of tongue	0.000	0.999	0.001
C02.2 Ventral surface of tongue	0.000	0.999	0.001
C02.0 Dorsal surface of tongue	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.999	0.001
O92.7 Other and unspecified disorders of lactation	0.001	0.999	0.000
O92.6 Galactorrhoea	0.001	0.999	0.000
O92.5 Suppressed lactation	0.001	0.999	0.000
O92.4 Hypogalactia	0.001	0.999	0.000
O92.3 Agalactia	0.001	0.999	0.000
O92.0 Retracted nipple associated with childbirth	0.001	0.999	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.999	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations