TreeWAS – Variant ID: rs12748152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.222	0.778	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.182	0.818	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.177	0.823	0.000
E78.8 Other disorders of lipoprotein metabolism	0.156	0.844	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.146	0.854	0.000
E78.6 Lipoprotein deficiency	0.127	0.873	0.000
E78.3 Hyperchylomicronaemia	0.127	0.873	0.000
E78.1 Pure hyperglyceridaemia	0.127	0.873	0.000
E78.4 Other hyperlipidaemia	0.126	0.873	0.000
E78.2 Mixed hyperlipidaemia	0.120	0.880	0.000
E70-E90 Metabolic disorders	0.114	0.886	0.000
E83 Disorders of mineral metabolism	0.105	0.895	0.000
E83.4 Disorders of magnesium metabolism	0.103	0.897	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.098	0.902	0.000
E74 Other disorders of carbohydrate metabolism	0.096	0.904	0.000
E78.5 Hyperlipidaemia, unspecified	0.094	0.906	0.000
E88 Other metabolic disorders	0.091	0.909	0.000
J30-J39 Other diseases of upper respiratory tract	0.089	0.911	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.088	0.912	0.000
Z42 Follow-up care involving plastic surgery	0.087	0.913	0.000
J34 Other disorders of nose and nasal sinuses	0.087	0.913	0.000
J34.3 Hypertrophy of nasal turbinates	0.086	0.914	0.000
E85 Amyloidosis	0.084	0.916	0.000
J38.3 Other diseases of vocal cords	0.084	0.916	0.000
J32 Chronic sinusitis	0.084	0.916	0.000
E83.3 Disorders of phosphorus metabolism	0.084	0.916	0.000
E73 Lactose intolerance	0.083	0.917	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.083	0.917	0.000
E84 Cystic fibrosis	0.082	0.918	0.000
E79 Disorders of purine and pyrimidine metabolism	0.082	0.918	0.000
E77 Disorders of glycoprotein metabolism	0.082	0.918	0.000
E76 Disorders of glycosaminoglycan metabolism	0.082	0.918	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.082	0.918	0.000
E72 Other disorders of amino-acid metabolism	0.082	0.918	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.082	0.918	0.000
E70 Disorders of aromatic amino-acid metabolism	0.082	0.918	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.082	0.918	0.000
J32.9 Chronic sinusitis, unspecified	0.082	0.918	0.000
E80.4 Gilbert's syndrome	0.081	0.918	0.000
H65.3 Chronic mucoid otitis media	0.000	0.918	0.082
J33 Nasal polyp	0.081	0.919	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.081	0.919	0.000
J38.2 Nodules of vocal cords	0.078	0.922	0.000
E80.2 Other porphyria	0.078	0.922	0.000
J33.0 Polyp of nasal cavity	0.077	0.923	0.000
J38.4 Oedema of larynx	0.076	0.923	0.000
H65 Nonsuppurative otitis media	0.000	0.924	0.076
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.076	0.924	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.076	0.924	0.000
E83.8 Other disorders of mineral metabolism	0.076	0.924	0.000
E83.2 Disorders of zinc metabolism	0.076	0.924	0.000
E83.0 Disorders of copper metabolism	0.076	0.924	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.925	0.075
J34.2 Deviated nasal septum	0.075	0.925	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.074	0.926	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.074	0.926	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.073	0.927	0.000
J33.9 Nasal polyp, unspecified	0.072	0.928	0.000
J38.6 Stenosis of larynx	0.070	0.929	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.070	0.930	0.000
E80.6 Other disorders of bilirubin metabolism	0.070	0.930	0.000
E80.5 Crigler-Najjar syndrome	0.070	0.930	0.000
E80.3 Defects of catalase and peroxydase	0.070	0.930	0.000
E80.1 Porphyria cutanea tarda	0.070	0.930	0.000
E80.0 Hereditary erythropoietic porphyria	0.070	0.930	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.070	0.930	0.000
J32.1 Chronic frontal sinusitis	0.069	0.931	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.069	0.931	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.069	0.931	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.069	0.931	0.000
E74.2 Disorders of galactose metabolism	0.069	0.931	0.000
E74.1 Disorders of fructose metabolism	0.069	0.931	0.000
E74.0 Glycogen storage disease	0.069	0.931	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.932	0.068
J31.0 Chronic rhinitis	0.067	0.933	0.000
J32.4 Chronic pansinusitis	0.066	0.933	0.000
H71 Cholesteatoma of middle ear	0.000	0.933	0.067
J38.5 Laryngeal spasm	0.065	0.934	0.000
J35 Chronic diseases of tonsils and adenoids	0.065	0.935	0.000
E88.9 Metabolic disorder, unspecified	0.065	0.935	0.000
E88.8 Other specified metabolic disorders	0.065	0.935	0.000
E88.3 Tumour lysis syndrome	0.065	0.935	0.000
E88.2 Lipomatosis, not elsewhere classified	0.065	0.935	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.065	0.935	0.000
J38.1 Polyp of vocal cord and larynx	0.065	0.935	0.000
J36 Peritonsillar abscess	0.065	0.935	0.000
H80-H83 Diseases of inner ear	0.000	0.935	0.065
H69 Other disorders of Eustachian tube	0.000	0.936	0.064
E85.4 Organ-limited amyloidosis	0.064	0.936	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.064	0.936	0.000
E89.3 Postprocedural hypopituitarism	0.063	0.936	0.000
H83 Other diseases of inner ear	0.000	0.937	0.063
H83.0 Labyrinthitis	0.000	0.937	0.063
Z42.9 Follow-up care involving plastic surgery, unspecified	0.063	0.937	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.063	0.937	0.000
H72 Perforation of tympanic membrane	0.000	0.939	0.061
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.061	0.939	0.000
E73.9 Lactose intolerance, unspecified	0.061	0.939	0.000
E85.8 Other amyloidosis	0.060	0.939	0.000
E85.3 Secondary systemic amyloidosis	0.060	0.939	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.060	0.939	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.060	0.939	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.060	0.939	0.000
J32.3 Chronic sphenoidal sinusitis	0.060	0.940	0.000
E73.8 Other lactose intolerance	0.060	0.940	0.000
E73.1 Secondary lactase deficiency	0.060	0.940	0.000
E73.0 Congenital lactase deficiency	0.060	0.940	0.000
H66 Suppurative and unspecified otitis media	0.000	0.940	0.060
H60-H62 Diseases of external ear	0.000	0.940	0.060
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.059	0.941	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.059	0.941	0.000
E70.3 Albinism	0.059	0.941	0.000
E70.2 Disorders of tyrosine metabolism	0.059	0.941	0.000
E70.1 Other hyperphenylalaninaemias	0.059	0.941	0.000
E70.0 Classical phenylketonuria	0.059	0.941	0.000
E71.3 Disorders of fatty-acid metabolism	0.059	0.941	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.059	0.941	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.059	0.941	0.000
E71.0 Maple-syrup-urine disease	0.059	0.941	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.059	0.941	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.059	0.941	0.000
E72.5 Disorders of glycine metabolism	0.059	0.941	0.000
E72.4 Disorders of ornithine metabolism	0.059	0.941	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.059	0.941	0.000
E72.2 Disorders of urea cycle metabolism	0.059	0.941	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.059	0.941	0.000
E72.0 Disorders of amino-acid transport	0.059	0.941	0.000
E75.6 Lipid storage disorder, unspecified	0.059	0.941	0.000
E75.5 Other lipid storage disorders	0.059	0.941	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.059	0.941	0.000
E75.3 Sphingolipidosis, unspecified	0.059	0.941	0.000
E75.2 Other sphingolipidosis	0.059	0.941	0.000
E75.1 Other gangliosidosis	0.059	0.941	0.000
E75.0 GM2 gangliosidosis	0.059	0.941	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.059	0.941	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.059	0.941	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.059	0.941	0.000
E76.2 Other mucopolysaccharidoses	0.059	0.941	0.000
E76.1 Mucopolysaccharidosis, type II	0.059	0.941	0.000
E76.0 Mucopolysaccharidosis, type I	0.059	0.941	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.059	0.941	0.000
E77.8 Other disorders of glycoprotein metabolism	0.059	0.941	0.000
E77.1 Defects in glycoprotein degradation	0.059	0.941	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.059	0.941	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.059	0.941	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.059	0.941	0.000
E79.1 Lesch-Nyhan syndrome	0.059	0.941	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.059	0.941	0.000
E84.9 Cystic fibrosis, unspecified	0.059	0.941	0.000
E84.8 Cystic fibrosis with other manifestations	0.059	0.941	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.059	0.941	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.059	0.941	0.000
E85.9 Amyloidosis, unspecified	0.059	0.941	0.000
J33.1 Polypoid sinus degeneration	0.058	0.942	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.058	0.942	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.058	0.942	0.000
E89.5 Postprocedural testicular hypofunction	0.058	0.942	0.000
E89.4 Postprocedural ovarian failure	0.058	0.942	0.000
E89.1 Postprocedural hypoinsulinaemia	0.058	0.942	0.000
E83.1 Disorders of iron metabolism	0.058	0.942	0.000
J32.8 Other chronic sinusitis	0.057	0.943	0.000
J37 Chronic laryngitis and laryngotracheitis	0.057	0.943	0.000
E83.5 Disorders of calcium metabolism	0.057	0.943	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.943	0.057
J31.2 Chronic pharyngitis	0.055	0.945	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.945	0.055
H65.0 Acute serous otitis media	0.000	0.945	0.055
J34.0 Abscess, furuncle and carbuncle of nose	0.055	0.945	0.000
E89.0 Postprocedural hypothyroidism	0.055	0.945	0.000
J31.1 Chronic nasopharyngitis	0.055	0.945	0.000
H61 Other disorders of external ear	0.000	0.945	0.055
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.946	0.054
H70 Mastoiditis and related conditions	0.000	0.946	0.054
H68 Eustachian salpingitis and obstruction	0.000	0.946	0.054
H67 Otitis media in diseases classified elsewhere	0.000	0.946	0.054
H69.9 Eustachian tube disorder, unspecified	0.000	0.946	0.054
J38.0 Paralysis of vocal cords and larynx	0.053	0.946	0.000
J39 Other diseases of upper respiratory tract	0.053	0.947	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.052	0.947	0.000
J32.0 Chronic maxillary sinusitis	0.052	0.948	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.948	0.052
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.949	0.051
H74 Other disorders of middle ear and mastoid	0.000	0.950	0.050
H90-H95 Other disorders of ear	0.000	0.950	0.050
H66.3 Other chronic suppurative otitis media	0.000	0.950	0.050
H65.2 Chronic serous otitis media	0.000	0.950	0.049
E89.2 Postprocedural hypoparathyroidism	0.049	0.951	0.000
H80 Otosclerosis	0.000	0.951	0.049
H69.8 Other specified disorders of Eustachian tube	0.000	0.951	0.049
H66.9 Otitis media, unspecified	0.000	0.951	0.049
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.047	0.953	0.000
J35.2 Hypertrophy of adenoids	0.047	0.953	0.000
J38.7 Other diseases of larynx	0.047	0.953	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.953	0.046
J35.1 Hypertrophy of tonsils	0.046	0.954	0.000
H69.0 Patulous Eustachian tube	0.000	0.954	0.046
J35.0 Chronic tonsillitis	0.046	0.954	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.954	0.046
H83.8 Other specified diseases of inner ear	0.000	0.954	0.046
H83.3 Noise effects on inner ear	0.000	0.954	0.046
H83.2 Labyrinthine dysfunction	0.000	0.954	0.046
H83.1 Labyrinthine fistula	0.000	0.954	0.046
H61.2 Impacted cerumen	0.000	0.954	0.045
H61.8 Other specified disorders of external ear	0.000	0.954	0.045
H61.1 Non-infective disorders of pinna	0.000	0.955	0.045
H72.2 Other marginal perforations of tympanic membrane	0.000	0.956	0.044
H72.1 Attic perforation of tympanic membrane	0.000	0.956	0.044
H61.0 Perichondritis of external ear	0.000	0.956	0.044
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.044	0.956	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.957	0.043
Chapter IV Endocrine, nutritional and metabolic diseases	0.043	0.957	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.957	0.043
H66.0 Acute suppurative otitis media	0.000	0.957	0.043
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.957	0.043
J32.2 Chronic ethmoidal sinusitis	0.042	0.958	0.000
H92 Otalgia and effusion of ear	0.000	0.958	0.042
H73 Other disorders of tympanic membrane	0.000	0.958	0.042
J37.1 Chronic laryngotracheitis	0.041	0.959	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.041	0.959	0.000
H60 Otitis externa	0.000	0.959	0.041
H72.0 Central perforation of tympanic membrane	0.000	0.959	0.041
H74.0 Tympanosclerosis	0.000	0.959	0.040
H81 Disorders of vestibular function	0.000	0.960	0.039
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.960	0.039
H61.9 Disorder of external ear, unspecified	0.000	0.961	0.039
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.961	0.039
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.961	0.039
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.961	0.039
H68.1 Obstruction of Eustachian tube	0.000	0.961	0.039
H68.0 Eustachian salpingitis	0.000	0.961	0.039
H70.9 Mastoiditis, unspecified	0.000	0.961	0.039
H70.8 Other mastoiditis and related conditions	0.000	0.961	0.039
H70.2 Petrositis	0.000	0.961	0.039
H70.1 Chronic mastoiditis	0.000	0.961	0.039
H70.0 Acute mastoiditis	0.000	0.961	0.039
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.961	0.039
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.961	0.039
H92.0 Otalgia	0.000	0.961	0.039
E00-E07 Disorders of thyroid gland	0.039	0.961	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.038	0.961	0.000
H80.9 Otosclerosis, unspecified	0.000	0.962	0.038
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.962	0.038
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.038	0.962	0.000
J39.1 Other abscess of pharynx	0.038	0.962	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.038	0.962	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.962	0.038
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.963	0.037
E03 Other hypothyroidism	0.037	0.963	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.037	0.963	0.000
J39.8 Other specified diseases of upper respiratory tract	0.036	0.964	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.964	0.036
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.964	0.036
H66.4 Suppurative otitis media, unspecified	0.000	0.964	0.036
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.964	0.036
E03.9 Hypothyroidism, unspecified	0.036	0.964	0.000
H80.8 Other otosclerosis	0.000	0.964	0.035
H80.2 Cochlear otosclerosis	0.000	0.964	0.035
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.964	0.035
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.964	0.035
E20-E35 Disorders of other endocrine glands	0.036	0.964	0.000
H81.0 Meniere's disease	0.000	0.965	0.035
J30 Vasomotor and allergic rhinitis	0.035	0.965	0.000
J37.0 Chronic laryngitis	0.034	0.965	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.966	0.034
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.967	0.033
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.967	0.033
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.967	0.032
E05 Thyrotoxicosis [hyperthyroidism]	0.032	0.968	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.032	0.968	0.000
H74.4 Polyp of middle ear	0.000	0.968	0.032
H74.1 Adhesive middle ear disease	0.000	0.968	0.032
H72.8 Other perforations of tympanic membrane	0.000	0.968	0.031
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.968	0.032
H90.0 Conductive hearing loss, bilateral	0.000	0.968	0.031
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.969	0.031
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.969	0.031
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.969	0.031
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.969	0.031
H62.2 Otitis externa in mycoses	0.000	0.969	0.031
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.969	0.031
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.969	0.031
E10-E14 Diabetes mellitus	0.031	0.969	0.000
H60.1 Cellulitis of external ear	0.000	0.970	0.030
E29 Testicular dysfunction	0.030	0.970	0.000
E22 Hyperfunction of pituitary gland	0.030	0.970	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.030	0.970	0.000
H92.2 Otorrhagia	0.000	0.970	0.030
H61.3 Acquired stenosis of external ear canal	0.000	0.970	0.030
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.970	0.030
H73.1 Chronic myringitis	0.000	0.970	0.030
H73.0 Acute myringitis	0.000	0.970	0.030
E50-E64 Other nutritional deficiencies	0.030	0.970	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.970	0.029
H60.8 Other otitis externa	0.000	0.970	0.029
H60.5 Acute otitis externa, non-infective	0.000	0.970	0.029
H60.4 Cholesteatoma of external ear	0.000	0.970	0.029
H60.3 Other infective otitis externa	0.000	0.970	0.029
H60.2 Malignant otitis externa	0.000	0.970	0.029
H60.0 Abscess of external ear	0.000	0.970	0.029
E14 Unspecified diabetes mellitus	0.029	0.970	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.971	0.029
H81.8 Other disorders of vestibular function	0.000	0.971	0.028
H81.4 Vertigo of central origin	0.000	0.971	0.028
H81.3 Other peripheral vertigo	0.000	0.971	0.028
E06 Thyroiditis	0.029	0.971	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.971	0.028
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.028	0.972	0.000
E00 Congenital iodine-deficiency syndrome	0.028	0.972	0.000
E27 Other disorders of adrenal gland	0.028	0.972	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.972	0.027
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.972	0.027
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.972	0.027
E20 Hypoparathyroidism	0.027	0.973	0.000
E14.9 Without complications	0.027	0.973	0.000
E34 Other endocrine disorders	0.027	0.973	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.027	0.973	0.000
E29.1 Testicular hypofunction	0.027	0.973	0.000
E03.8 Other specified hypothyroidism	0.026	0.973	0.000
E03.5 Myxoedema coma	0.026	0.973	0.000
E03.4 Atrophy of thyroid (acquired)	0.026	0.973	0.000
E03.3 Postinfectious hypothyroidism	0.026	0.973	0.000
E03.1 Congenital hypothyroidism without goitre	0.026	0.973	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.026	0.973	0.000
E22.0 Acromegaly and pituitary gigantism	0.026	0.974	0.000
H60.9 Otitis externa, unspecified	0.000	0.974	0.026
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.974	0.026
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.974	0.026
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.026	0.974	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.026	0.974	0.000
E32 Diseases of thymus	0.026	0.974	0.000
E31 Polyglandular dysfunction	0.026	0.974	0.000
E30 Disorders of puberty, not elsewhere classified	0.026	0.974	0.000
E25 Adrenogenital disorders	0.026	0.974	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.026	0.974	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.026	0.974	0.000
J30.2 Other seasonal allergic rhinitis	0.025	0.975	0.000
J30.0 Vasomotor rhinitis	0.025	0.975	0.000
E22.1 Hyperprolactinaemia	0.025	0.975	0.000
E40-E46 Malnutrition	0.025	0.975	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.975	0.025
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.025	0.975	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.975	0.024
J39.2 Other diseases of pharynx	0.024	0.976	0.000
E14.8 With unspecified complications	0.024	0.976	0.000
J30.4 Allergic rhinitis, unspecified	0.024	0.976	0.000
E14.3 With ophthalmic complications	0.024	0.976	0.000
H81.2 Vestibular neuronitis	0.000	0.976	0.023
E24 Cushing's syndrome	0.024	0.976	0.000
E05.8 Other thyrotoxicosis	0.023	0.976	0.000
E05.5 Thyroid crisis or storm	0.023	0.976	0.000
E05.4 Thyrotoxicosis factitia	0.023	0.976	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.023	0.976	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.023	0.976	0.000
H91 Other hearing loss	0.000	0.976	0.023
E26 Hyperaldosteronism	0.023	0.977	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.023	0.977	0.000
E13 Other specified diabetes mellitus	0.023	0.977	0.000
E27.9 Disorder of adrenal gland, unspecified	0.023	0.977	0.000
E23 Hypofunction and other disorders of pituitary gland	0.022	0.977	0.000
E12 Malnutrition-related diabetes mellitus	0.022	0.978	0.000
E55 Vitamin D deficiency	0.022	0.978	0.000
E29.9 Testicular dysfunction, unspecified	0.022	0.978	0.000
E29.8 Other testicular dysfunction	0.022	0.978	0.000
E29.0 Testicular hyperfunction	0.022	0.978	0.000
J30.3 Other allergic rhinitis	0.022	0.978	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.022	0.978	0.000
E22.8 Other hyperfunction of pituitary gland	0.022	0.978	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.021	0.978	0.000
E63 Other nutritional deficiencies	0.021	0.978	0.000
E56 Other vitamin deficiencies	0.021	0.978	0.000
E51 Thiamine deficiency	0.021	0.978	0.000
E50 Vitamin A deficiency	0.021	0.978	0.000
E60 Dietary zinc deficiency	0.021	0.978	0.000
E59 Dietary selenium deficiency	0.021	0.978	0.000
E58 Dietary calcium deficiency	0.021	0.978	0.000
E54 Ascorbic acid deficiency	0.021	0.978	0.000
E52 Niacin deficiency [pellagra]	0.021	0.978	0.000
E06.3 Autoimmune thyroiditis	0.021	0.978	0.000
E20.9 Hypoparathyroidism, unspecified	0.021	0.979	0.000
E14.7 With multiple complications	0.021	0.979	0.000
E14.6 With other specified complications	0.021	0.979	0.000
E14.5 With peripheral circulatory complications	0.021	0.979	0.000
E14.4 With neurological complications	0.021	0.979	0.000
E14.2 Withrenal complications	0.021	0.979	0.000
E14.1 With ketoacidosis	0.021	0.979	0.000
E14.0 With coma	0.021	0.979	0.000
E34.9 Endocrine disorder, unspecified	0.021	0.979	0.000
E65-E68 Obesity and other hyperalimentation	0.021	0.979	0.000
E27.2 Addisonian crisis	0.021	0.979	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.021	0.979	0.000
E53 Deficiency of other B group vitamins	0.021	0.979	0.000
E06.5 Other chronic thyroiditis	0.021	0.979	0.000
E06.4 Drug-induced thyroiditis	0.021	0.979	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.021	0.979	0.000
E06.1 Subacute thyroiditis	0.021	0.979	0.000
E06.0 Acute thyroiditis	0.021	0.979	0.000
E06.9 Thyroiditis, unspecified	0.020	0.979	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.020	0.980	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.020	0.980	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.020	0.980	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.020	0.980	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.020	0.980	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.020	0.980	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.020	0.980	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.020	0.980	0.000
E28 Ovarian dysfunction	0.020	0.980	0.000
H92.1 Otorrhoea	0.000	0.980	0.020
E27.5 Adrenomedullary hyperfunction	0.020	0.980	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.020	0.980	0.000
E27.0 Other adrenocortical overactivity	0.020	0.980	0.000
E07 Other disorders of thyroid	0.020	0.980	0.000
E61 Deficiency of other nutrient elements	0.020	0.980	0.000
E20.8 Other hypoparathyroidism	0.020	0.980	0.000
E20.1 Pseudohypoparathyroidism	0.020	0.980	0.000
E20.0 Idiopathic hypoparathyroidism	0.020	0.980	0.000
E34.8 Other specified endocrine disorders	0.020	0.980	0.000
E34.5 Androgen resistance syndrome	0.020	0.980	0.000
E34.4 Constitutional tall stature	0.020	0.980	0.000
E34.3 Short stature, not elsewhere classified	0.020	0.980	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.020	0.980	0.000
E34.1 Other hypersecretion of intestinal hormones	0.020	0.980	0.000
E34.0 Carcinoid syndrome	0.020	0.980	0.000
E27.1 Primary adrenocortical insufficiency	0.019	0.980	0.000
E21.3 Hyperparathyroidism, unspecified	0.019	0.981	0.000
E15 Nondiabetic hypoglycaemic coma	0.019	0.981	0.000
E25.9 Adrenogenital disorder, unspecified	0.019	0.981	0.000
E25.8 Other adrenogenital disorders	0.019	0.981	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.019	0.981	0.000
E30.9 Disorder of puberty, unspecified	0.019	0.981	0.000
E30.8 Other disorders of puberty	0.019	0.981	0.000
E30.1 Precocious puberty	0.019	0.981	0.000
E30.0 Delayed puberty	0.019	0.981	0.000
E31.9 Polyglandular dysfunction, unspecified	0.019	0.981	0.000
E31.8 Other polyglandular dysfunction	0.019	0.981	0.000
E31.1 Polyglandular hyperfunction	0.019	0.981	0.000
E31.0 Autoimmune polyglandular failure	0.019	0.981	0.000
E32.9 Disease of thymus, unspecified	0.019	0.981	0.000
E32.8 Other diseases of thymus	0.019	0.981	0.000
E32.1 Abscess of thymus	0.019	0.981	0.000
E32.0 Persistent hyperplasia of thymus	0.019	0.981	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.019	0.981	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.019	0.981	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.019	0.981	0.000
J33.8 Other polyp of sinus	0.018	0.981	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.018	0.982	0.000
E45 Retarded development following protein-energy malnutrition	0.018	0.982	0.000
E43 Unspecified severe protein-energy malnutrition	0.018	0.982	0.000
E42 Marasmic kwashiorkor	0.018	0.982	0.000
E41 Nutritional marasmus	0.018	0.982	0.000
E40 Kwashiorkor	0.018	0.982	0.000
H91.8 Other specified hearing loss	0.000	0.982	0.018
E21.5 Disorder of parathyroid gland, unspecified	0.018	0.982	0.000
E21.4 Other specified disorders of parathyroid gland	0.018	0.982	0.000
E21.2 Other hyperparathyroidism	0.018	0.982	0.000
E13.9 Without complications	0.018	0.982	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.018	0.982	0.000
H93.9 Disorder of ear, unspecified	0.000	0.982	0.018
H93.2 Other abnormal auditory perceptions	0.000	0.982	0.018
H93.0 Degenerative and vascular disorders of ear	0.000	0.982	0.018
H73.8 Other specified disorders of tympanic membrane	0.000	0.982	0.017
E23.0 Hypopituitarism	0.017	0.983	0.000
E24.8 Other Cushing's syndrome	0.017	0.983	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.017	0.983	0.000
E24.3 Ectopic ACTH syndrome	0.017	0.983	0.000
E24.2 Drug-induced Cushing's syndrome	0.017	0.983	0.000
E24.1 Nelson's syndrome	0.017	0.983	0.000
E24.0 Pituitary-dependent Cushing's disease	0.017	0.983	0.000
E86 Volume depletion	0.017	0.983	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.983	0.017
H91.1 Presbycusis	0.000	0.983	0.017
H91.0 Ototoxic hearing loss	0.000	0.983	0.017
E26.9 Hyperaldosteronism, unspecified	0.017	0.983	0.000
E26.8 Other hyperaldosteronism	0.017	0.983	0.000
E26.1 Secondary hyperaldosteronism	0.017	0.983	0.000
H93.8 Other specified disorders of ear	0.000	0.983	0.017
E13.8 With unspecified complications	0.017	0.983	0.000
E13.7 With multiple complications	0.017	0.983	0.000
E13.6 With other specified complications	0.017	0.983	0.000
E13.5 With peripheral circulatory complications	0.017	0.983	0.000
E13.4 With neurological complications	0.017	0.983	0.000
E13.3 With ophthalmic complications	0.017	0.983	0.000
E13.2 With renal complications	0.017	0.983	0.000
E13.1 With ketoacidosis	0.017	0.983	0.000
E13.0 With coma	0.017	0.983	0.000
E55.9 Vitamin D deficiency, unspecified	0.017	0.983	0.000
E23.7 Disorder of pituitary gland, unspecified	0.016	0.983	0.000
E23.6 Other disorders of pituitary gland	0.016	0.984	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.016	0.984	0.000
E23.1 Drug-induced hypopituitarism	0.016	0.984	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.984	0.016
E12.9 Without complications	0.016	0.984	0.000
E12.8 With unspecified complications	0.016	0.984	0.000
E12.7 With multiple complications	0.016	0.984	0.000
E12.6 With other specified complications	0.016	0.984	0.000
E12.5 With peripheral circulatory complications	0.016	0.984	0.000
E12.4 With neurological complications	0.016	0.984	0.000
E12.3 With ophthalmic complications	0.016	0.984	0.000
E12.2 With renal complications	0.016	0.984	0.000
E12.1 With ketoacidosis	0.016	0.984	0.000
E12.0 With coma	0.016	0.984	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations