TreeWAS – Variant ID: rs12818741

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000	0.000
D12.5 Sigmoid colon	1.000	0.000	0.000
D12.3 Transverse colon	0.999	0.001	0.000
D12.2 Ascending colon	0.998	0.002	0.000
D12.7 Rectosigmoid junction	0.957	0.043	0.000
D12.8 Rectum	0.932	0.068	0.000
D12.0 Caecum	0.895	0.105	0.000
D12.1 Appendix	0.724	0.276	0.000
D12.4 Descending colon	0.546	0.454	0.000
D12.9 Anus and anal canal	0.370	0.629	0.001
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.166	0.834	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.839	0.161
D22 Melanocytic naevi	0.000	0.840	0.160
D22.5 Melanocytic naevi of trunk	0.000	0.846	0.154
D22.0 Melanocytic naevi of lip	0.000	0.847	0.153
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.853	0.147
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.864	0.136
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.871	0.129
D12.6 Colon, unspecified	0.107	0.893	0.000
D22.9 Melanocytic naevi, unspecified	0.000	0.912	0.088
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.918	0.082
D22.4 Melanocytic naevi of scalp and neck	0.000	0.925	0.075
I83 Varicose veins of lower extremities	0.069	0.931	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.064	0.936	0.000
N21.0 Calculus in bladder	0.043	0.957	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.040	0.960	0.000
C67.9 Bladder, unspecified	0.030	0.970	0.000
C67 Malignant neoplasm of bladder	0.027	0.973	0.000
C67.4 Posterior wall of bladder	0.024	0.976	0.000
C67.1 Dome of bladder	0.024	0.976	0.000
N21 Calculus of lower urinary tract	0.023	0.977	0.000
C67.5 Bladder neck	0.022	0.978	0.000
C67.2 Lateral wall of bladder	0.021	0.979	0.000
N32.0 Bladder-neck obstruction	0.021	0.979	0.000
C67.0 Trigone of bladder	0.021	0.979	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.021	0.979	0.000
N32 Other disorders of bladder	0.021	0.979	0.000
G47.3 Sleep apnoea	0.020	0.980	0.000
N32.3 Diverticulum of bladder	0.020	0.980	0.000
N21.1 Calculus in urethra	0.020	0.980	0.000
C67.7 Urachus	0.019	0.980	0.000
N32.9 Bladder disorder, unspecified	0.019	0.981	0.000
N32.1 Vesicointestinal fistula	0.019	0.981	0.000
C67.6 Ureteric orifice	0.019	0.981	0.000
C67.8 Overlapping lesion of bladder	0.018	0.981	0.000
C67.3 Anterior wall of bladder	0.018	0.982	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.017	0.983	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.017	0.983	0.000
N21.8 Other lower urinary tract calculus	0.017	0.983	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.985	0.015
N32.4 Rupture of bladder, nontraumatic	0.015	0.985	0.000
R41.3 Other amnesia	0.014	0.986	0.000
N32.2 Vesical fistula, not elsewhere classified	0.013	0.986	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.013	0.987	0.000
K60.3 Anal fistula	0.000	0.987	0.013
S22.40 Multiple fractures of ribs (closed)	0.000	0.987	0.013
R41.2 Retrograde amnesia	0.012	0.988	0.000
K60.0 Acute anal fissure	0.000	0.988	0.012
N30-N39 Other diseases of urinary system	0.012	0.988	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.011	0.989	0.000
N35 Urethral stricture	0.011	0.989	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.989	0.011
N35.9 Urethral stricture, unspecified	0.011	0.989	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.010	0.990	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.010	0.990	0.000
N39.8 Other specified disorders of urinary system	0.010	0.990	0.000
R41.1 Anterograde amnesia	0.009	0.991	0.000
N35.0 Posttraumatic urethral stricture	0.009	0.991	0.000
K60.2 Anal fissure, unspecified	0.000	0.991	0.009
N37 Urethral disorders in diseases classified elsewhere	0.009	0.991	0.000
N33 Bladder disorders in diseases classified elsewhere	0.009	0.991	0.000
C92.0 Acute myeloid leukaemia	0.000	0.991	0.009
C64-C68 Malignant neoplasms of urinary tract	0.009	0.991	0.000
K60.5 Anorectal fistula	0.000	0.991	0.009
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.008	0.991	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.008	0.992	0.000
N34 Urethritis and urethral syndrome	0.008	0.992	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.008	0.992	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.008	0.992	0.000
K60.4 Rectal fistula	0.000	0.992	0.008
C65 Malignant neoplasm of renal pelvis	0.008	0.992	0.000
N39 Other disorders of urinary system	0.008	0.992	0.000
S22.4 Multiple fractures of ribs	0.000	0.992	0.008
S52.10 Fracture of upper end of radius (closed)	0.008	0.992	0.000
C15.5 Lower third of oesophagus	0.007	0.993	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.007	0.993	0.000
N35.8 Other urethral stricture	0.007	0.993	0.000
L30.9 Dermatitis, unspecified	0.007	0.993	0.000
N39.1 Persistent proteinuria, unspecified	0.007	0.993	0.000
N30 Cystitis	0.007	0.993	0.000
G47 Sleep disorders	0.007	0.993	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.007	0.993	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.007	0.993	0.000
N33.8 Bladder disorders in other diseases classified elsewhere	0.006	0.993	0.000
N33.0 Tuberculous cystitis	0.006	0.993	0.000
N37.8 Other urethral disorders in diseases classified elsewhere	0.006	0.993	0.000
N37.0 Urethritis in diseases classified elsewhere	0.006	0.993	0.000
N34.3 Urethral syndrome, unspecified	0.006	0.994	0.000
C68.0 Urethra	0.006	0.994	0.000
C15.3 Upper third of oesophagus	0.006	0.994	0.000
N30.9 Cystitis, unspecified	0.006	0.994	0.000
C15 Malignant neoplasm of oesophagus	0.006	0.994	0.000
N34.0 Urethral abscess	0.006	0.994	0.000
N34.1 Nonspecific urethritis	0.006	0.994	0.000
N30.2 Other chronic cystitis	0.006	0.994	0.000
N39.2 Orthostatic proteinuria, unspecified	0.006	0.994	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.994	0.006
K60.1 Chronic anal fissure	0.000	0.994	0.006
C15.9 Oesophagus, unspecified	0.006	0.994	0.000
N34.2 Other urethritis	0.006	0.994	0.000
G47.2 Disorders of the sleep-wake schedule	0.005	0.994	0.000
N30.4 Irradiation cystitis	0.005	0.994	0.000
C68.8 Overlapping lesion of urinary organs	0.005	0.995	0.000
C68.1 Paraurethral glands	0.005	0.995	0.000
C15.1 Thoracic part of oesophagus	0.005	0.995	0.000
C68.9 Urinary organ, unspecified	0.005	0.995	0.000
N39.4 Other specified urinary incontinence	0.005	0.995	0.000
M88.9 Paget's disease of bone, unspecified	0.005	0.995	0.000
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
C15.8 Overlapping lesion of oesophagus	0.005	0.995	0.000
C15.2 Abdominal part of oesophagus	0.005	0.995	0.000
G47.8 Other sleep disorders	0.005	0.995	0.000
N30.0 Acute cystitis	0.005	0.995	0.000
C66 Malignant neoplasm of ureter	0.004	0.996	0.000
C15.4 Middle third of oesophagus	0.004	0.996	0.000
F31.7 Bipolar affective disorder, currently in remission	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.996	0.004
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
E78.5 Hyperlipidaemia, unspecified	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.004	0.996	0.000
F31 Bipolar affective disorder	0.004	0.996	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.996	0.004
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.004
L30 Other dermatitis	0.004	0.996	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.004	0.996	0.000
S22.2 Fracture of sternum	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
M88.98 Paget's disease of bone, unspecified (Other)	0.004	0.996	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.004	0.996	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.004	0.996	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.004	0.996	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.004	0.996	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.004	0.996	0.000
N39.9 Disorder of urinary system, unspecified	0.004	0.996	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
F31.8 Other bipolar affective disorders	0.004	0.996	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.004	0.996	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.004	0.996	0.000
G47.4 Narcolepsy and cataplexy	0.003	0.996	0.000
F31.9 Bipolar affective disorder, unspecified	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.000	0.996	0.004
M23.49 Loose body in knee-Unspec lig/men	0.004	0.996	0.000
L30.4 Erythema intertrigo	0.003	0.996	0.000
L30.1 Dyshidrosis [pompholyx]	0.003	0.997	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.997	0.003
N30.3 Trigonitis	0.003	0.997	0.000
R41.0 Disorientation, unspecified	0.003	0.997	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.003
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
L30.5 Pityriasis alba	0.003	0.997	0.000
L30.2 Cutaneous autosensitisation	0.003	0.997	0.000
L30.0 Nummular dermatitis	0.003	0.997	0.000
J91 Pleural effusion in conditions classified elsewhere	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.000	0.997	0.003
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.003
L30.8 Other specified dermatitis	0.003	0.997	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.003	0.997	0.000
S52.1 Fracture of upper end of radius	0.003	0.997	0.000
K14.0 Glossitis	0.003	0.997	0.000
N36 Other disorders of urethra	0.003	0.997	0.000
L30.3 Infective dermatitis	0.003	0.997	0.000
N30.1 Interstitial cystitis (chronic)	0.003	0.997	0.000
S22.3 Fracture of rib	0.000	0.997	0.003
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
S22.5 Flail chest	0.000	0.997	0.003
I24.9 Acute ischaemic heart disease, unspecified	0.003	0.997	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.997	0.003
T25.2 Burn of second degree of ankle and foot	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.997	0.000
I24.8 Other forms of acute ischaemic heart disease	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.003	0.997	0.000
C92 Myeloid leukaemia	0.000	0.997	0.003
I24 Other acute ischaemic heart diseases	0.003	0.997	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
Z03.3 Observation for suspected nervous system disorder	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.002	0.998	0.000
I24.1 Dressler's syndrome	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
N30.8 Other cystitis	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.998	0.002
N36.9 Urethral disorder, unspecified	0.002	0.998	0.000
S22.51 Flail chest (open)	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
X23.9 Unspecified place	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
K62.7 Radiation proctitis	0.002	0.998	0.000
N36.1 Urethral diverticulum	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
M23.4 Loose body in knee	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.001
N36.3 Prolapsed urethral mucosa	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.002	0.998	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
K56.1 Intussusception	0.002	0.998	0.000
M88.8 Paget's disease of other bones	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
M88.0 Paget's disease of skull	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.002
M23.40 Loose body in knee-Mult sites	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.000	0.998	0.002
Z03.6 Observation for suspected toxic effect from ingested substance	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.002	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.002	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.998	0.000
N36.2 Urethral caruncle	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.002	0.998	0.000
D37.4 Colon	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
X23.0 Home	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.001
T25.3 Burn of third degree of ankle and foot	0.002	0.998	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.002	0.998	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.001	0.998	0.000
M88.88 Paget's disease of other bones (Other)	0.001	0.998	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.001	0.998	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.001	0.998	0.000
M88.84 Paget's disease of other bones (Hand)	0.001	0.998	0.000
M88.83 Paget's disease of other bones (Forearm)	0.001	0.998	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.001	0.998	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.001	0.998	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.001	0.998	0.000
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
M88.09 Paget's disease of skull-Site unspec	0.001	0.998	0.000
M88.08 Paget's disease of skull-Other	0.001	0.998	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.001	0.998	0.000
M88.06 Paget's disease of skull-Lower Leg	0.001	0.998	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.001	0.998	0.000
M88.04 Paget's disease of skull-Hand	0.001	0.998	0.000
M88.03 Paget's disease of skull-Forearm	0.001	0.998	0.000
M88.02 Paget's disease of skull-Upper arm	0.001	0.998	0.000
M88.01 Paget's disease of skull-Shldr region	0.001	0.998	0.000
M88.00 Paget's disease of skull-Mult sites	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.000	0.998	0.002
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.998	0.000
N36.0 Urethral fistula	0.001	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.001	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.001	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.001	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.001	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.001	0.998	0.000
N20-N23 Urolithiasis	0.002	0.998	0.000
E11.9 Without complications	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
S02.6 Fracture of mandible	0.002	0.998	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
R46 Symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.000	0.998	0.001
X23.8 Other specified place	0.001	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.998	0.002
R46.0 Very low level of personal hygiene	0.001	0.998	0.000
H44.4 Hypotony of eye	0.000	0.998	0.001
Z31.2 In vitro fertilisation	0.000	0.998	0.001
H44.2 Degenerative myopia	0.000	0.998	0.001
X23.7 Farm	0.001	0.998	0.000
X23.6 Industrial and construction area	0.001	0.998	0.000
X23.5 Trade and service area	0.001	0.998	0.000
X23.4 Street and highway	0.001	0.998	0.000
X23.3 Sports and athletics area	0.001	0.998	0.000
X23.2 School, other institution and public administrative area	0.001	0.998	0.000
X23.1 Residential institution	0.001	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.999	0.001
N32.8 Other specified disorders of bladder	0.001	0.999	0.000
R46.2 Strange and inexplicable behaviour	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.001	0.999	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.001	0.999	0.000
S02 Fracture of skull and facial bones	0.001	0.999	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.999	0.000
A08.4 Viral intestinal infection, unspecified	0.001	0.999	0.000
K14.8 Other diseases of tongue	0.001	0.999	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
C84.5 Other and unspecified T-cell lymphomas	0.001	0.999	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.000	0.999	0.001
D07.5 Prostate	0.001	0.999	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.999	0.001
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.001	0.999	0.000
R46.6 Undue concern and preoccupation with stressful events	0.001	0.999	0.000
R46.5 Suspiciousness and marked evasiveness	0.001	0.999	0.000
R46.3 Overactivity	0.001	0.999	0.000
R46.1 Bizarre personal appearance	0.001	0.999	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
S02.5 Fracture of tooth	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.999	0.001
I71.0 Dissection of aorta [any part]	0.001	0.999	0.000
I77.0 Arteriovenous fistula, acquired	0.001	0.999	0.000
J93.8 Other pneumothorax	0.000	0.999	0.001
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.001	0.999	0.000
S19.9 Unspecified injury of neck	0.001	0.999	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.999	0.001
B44.1 Other pulmonary aspergillosis	0.001	0.999	0.000
K14.3 Hypertrophy of tongue papillae	0.001	0.999	0.000
N90.5 Atrophy of vulva	0.001	0.999	0.000
U89 Agent resistant to other and unspecified antibiotics	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.999	0.001
T17.3 Foreign body in larynx	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.999	0.001
K14 Diseases of tongue	0.001	0.999	0.000
U84 Resistance to other antimicrobial drugs	0.001	0.999	0.000
U83 Resistance to other antibiotics	0.001	0.999	0.000
U82 Resistance to betalactam antibiotics	0.001	0.999	0.000
U85 Resistance to antineoplastic drugs	0.001	0.999	0.000
H66.9 Otitis media, unspecified	0.000	0.999	0.001
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.001	0.999	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.001	0.999	0.000
Z03.2 Observation for suspected mental and behavioural disorders	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.999	0.001
S32.5 Fracture of pubis	0.000	0.999	0.001
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.001	0.999	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
S02.01 Fracture of vault of skull (open)	0.001	0.999	0.000
S02.00 Fracture of vault of skull (closed)	0.001	0.999	0.000
S02.50 Fracture of tooth (closed)	0.001	0.999	0.000
U89.9 Agent resistant to unspecified antibiotic	0.001	0.999	0.000
X63.0 Home	0.000	0.999	0.001
S02.51 Fracture of tooth (open)	0.001	0.999	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
R44.2 Other hallucinations	0.001	0.999	0.000
S65.5 Injury of blood vessel(s) of other finger	0.000	0.999	0.001
X10.0 Home	0.001	0.999	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.999	0.001
Z97 Presence of other devices	0.000	0.999	0.001
C38.4 Pleura	0.001	0.999	0.000
K14.6 Glossodynia	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
S02.4 Fracture of malar and maxillary bones	0.001	0.999	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.001	0.999	0.000
U82.8 Resistance to other betalactam antibiotics	0.001	0.999	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.001	0.999	0.000
U82.1 Resistance to methicillin	0.001	0.999	0.000
U82.0 Resistance to penicillin	0.001	0.999	0.000
U83.9 Resistance to unspecified antibiotic	0.001	0.999	0.000
U83.8 Resistance to other single specified antibiotic	0.001	0.999	0.000
U83.7 Resistance to multiple antibiotics	0.001	0.999	0.000
U83.2 Resistance to quinolones	0.001	0.999	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.001	0.999	0.000
U83.0 Resistance to vancomycin	0.001	0.999	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.001	0.999	0.000
U84.8 Resistance to other specified antimicrobial drug	0.001	0.999	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.001	0.999	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.001	0.999	0.000
U84.2 Resistance to antiviral drug(s)	0.001	0.999	0.000
U84.1 Resistance to antifungal drug(s)	0.001	0.999	0.000
U84.0 Resistance to antiparasitic drug(s)	0.001	0.999	0.000
Z43.3 Attention to colostomy	0.001	0.999	0.000
I22 Subsequent myocardial infarction	0.001	0.999	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.999	0.001
K14.5 Plicated tongue	0.001	0.999	0.000
K14.4 Atrophy of tongue papillae	0.001	0.999	0.000
K14.2 Median rhomboid glossitis	0.001	0.999	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.999	0.000
Z97.4 Presence of external hearing-aid	0.000	0.999	0.001
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.999	0.001
H55 Nystagmus and other irregular eye movements	0.000	0.999	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
H44.0 Purulent endophthalmitis	0.000	0.999	0.001
N90.1 Moderate vulvar dysplasia	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
Z03.0 Observation for suspected tuberculosis	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
G82.5 Tetraplegia, unspecified	0.001	0.999	0.000
K14.1 Geographic tongue	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.999	0.000
S02.1 Fracture of base of skull	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.001	0.999	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
D48.7 Other specified sites	0.000	0.999	0.001
R46.4 Slowness and poor responsiveness	0.001	0.999	0.000
O72.1 Other immediate postpartum haemorrhage	0.001	0.999	0.000
X59.3 Sports and athletics area	0.001	0.999	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.001	0.999	0.000
N85.2 Hypertrophy of uterus	0.001	0.999	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
R42 Dizziness and giddiness	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.999	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.999	0.001
O75.0 Maternal distress during labour and delivery	0.001	0.999	0.000
Q44.6 Cystic disease of liver	0.000	0.999	0.001
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.999	0.001
S02.40 Fracture of malar and maxillary bones (closed)	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.000	0.999	0.001
Z12.0 Special screening examination for neoplasm of stomach	0.000	0.999	0.001
C45.9 Mesothelioma, unspecified	0.000	0.999	0.001
C60.9 Penis, unspecified	0.001	0.999	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.999	0.001
N64.8 Other specified disorders of breast	0.000	0.999	0.001
T17.5 Foreign body in bronchus	0.001	0.999	0.000
Z97.0 Presence of artificial eye	0.000	0.999	0.001
R43 Disturbances of smell and taste	0.001	0.999	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.001	0.999	0.000
E78.8 Other disorders of lipoprotein metabolism	0.001	0.999	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.001	0.999	0.000
S83.3 Tear of articular cartilage of knee, current	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.999	0.001
Z97.3 Presence of spectacles and contact lenses	0.000	0.999	0.001
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.999	0.001
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
R43.2 Parageusia	0.001	0.999	0.000
Z31.8 Other procreative management	0.000	0.999	0.001
H44 Disorders of globe	0.000	0.999	0.001
H66 Suppurative and unspecified otitis media	0.000	0.999	0.001
M25.54 Pain in joint (Hand)	0.000	0.999	0.001
S02.11 Fracture of base of skull (open)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations