TreeWAS – Variant ID: rs12821256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D03.3 Melanoma in situ of other and unspecified parts of face	0.019	0.980	0.000
H33.0 Retinal detachment with retinal break	0.018	0.982	0.000
S62.60 Fracture of other finger (closed)	0.000	0.984	0.016
H33 Retinal detachments and breaks	0.016	0.984	0.000
H33.3 Retinal breaks without detachment	0.016	0.984	0.000
D03 Melanoma in situ	0.015	0.985	0.000
H33.5 Other retinal detachments	0.014	0.986	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.013	0.987	0.000
H33.4 Traction detachment of retina	0.013	0.987	0.000
Z72.1 Alcohol use	0.000	0.987	0.013
D03.5 Melanoma in situ of trunk	0.013	0.987	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.987	0.013
S62.6 Fracture of other finger	0.000	0.988	0.012
H33.1 Retinoschisis and retinal cysts	0.012	0.988	0.000
S62.61 Fracture of other finger (open)	0.000	0.988	0.012
D03.6 Melanoma in situ of upper limb, including shoulder	0.012	0.988	0.000
D03.9 Melanoma in situ, unspecified	0.011	0.989	0.000
D03.8 Melanoma in situ of other sites	0.011	0.989	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.011	0.989	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.011	0.989	0.000
D03.0 Melanoma in situ of lip	0.011	0.989	0.000
D03.4 Melanoma in situ of scalp and neck	0.009	0.991	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.991	0.009
H33.2 Serous retinal detachment	0.007	0.993	0.000
O80.9 Single spontaneous delivery, unspecified	0.006	0.994	0.000
Z72 Problems related to lifestyle	0.000	0.995	0.005
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.995	0.005
Z72.2 Drug use	0.000	0.995	0.005
Y45.1 Salicylates	0.005	0.995	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.996	0.004
M47.87 Other spondylosis (Lumbosacral region)	0.004	0.996	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.996	0.004
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.996	0.004
Z72.9 Problem related to lifestyle, unspecified	0.000	0.996	0.004
Z72.8 Other problems related to lifestyle	0.000	0.996	0.004
Z72.6 Gambling and betting	0.000	0.996	0.004
Z72.5 High-risk sexual behaviour	0.000	0.996	0.004
Z72.3 Lack of physical exercise	0.000	0.996	0.004
Z72.4 Inappropriate diet and eating habits	0.000	0.996	0.004
C77.3 Axillary and upper limb lymph nodes	0.004	0.996	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
Z97.8 Presence of other specified devices	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.000	0.996	0.004
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.996	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
M80 Osteoporosis with pathological fracture	0.000	0.997	0.003
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.997	0.003
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
R29.4 Clicking hip	0.000	0.997	0.003
R29.3 Abnormal posture	0.000	0.997	0.003
R29.2 Abnormal reflex	0.000	0.997	0.003
R29.1 Meningismus	0.000	0.997	0.003
R29.0 Tetany	0.000	0.997	0.003
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.997	0.003
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.997	0.003
O12.1 Gestational proteinuria	0.003	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.997	0.003
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.997	0.003
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.997	0.003
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.997	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
C77.1 Intrathoracic lymph nodes	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
N87 Dysplasia of cervix uteri	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.998	0.002
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Z97 Presence of other devices	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
Z97.0 Presence of artificial eye	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
R63.4 Abnormal weight loss	0.000	0.998	0.002
D68 Other coagulation defects	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.002	0.998	0.000
Y83.6 Removal of other organ (partial) (total)	0.000	0.998	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
Z97.1 Presence of artificial limb (complete)(partial)	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.002
R60.0 Localised oedema	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.000	0.998	0.002
Z70-Z76 Persons encountering health services in other circumstances	0.000	0.998	0.002
I51.7 Cardiomegaly	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
S92.1 Fracture of talus	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
Z97.3 Presence of spectacles and contact lenses	0.002	0.998	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
N76.4 Abscess of vulva	0.000	0.998	0.002
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
O80 Single spontaneous delivery	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
O12.0 Gestational oedema	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.002	0.998	0.000
Z76 Persons encountering health services in other circumstances	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
C53.9 Cervix uteri, unspecified	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
R80 Isolated proteinuria	0.000	0.998	0.002
Z75 Problems related to medical facilities and other health care	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.001
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.001
C71.1 Frontal lobe	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
Z74.1 Need for assistance with personal care	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.000	0.998	0.002
Z70 Counselling related to sexual attitude, behaviour and orientation	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
Z75.8 Other problems related to medical facilities and other health care	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.001
R26.0 Ataxic gait	0.000	0.998	0.002
S92.4 Fracture of great toe	0.001	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.001
S92.5 Fracture of other toe	0.001	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.000	0.998	0.001
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.001	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.001
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.001
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.001
M85 Other disorders of bone density and structure	0.000	0.998	0.002
R25.2 Cramp and spasm	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.001
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.000	0.998	0.001
N76.0 Acute vaginitis	0.000	0.998	0.002
O80.1 Spontaneous breech delivery	0.001	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.002	0.998	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.998	0.001
Z74.3 Need for continuous supervision	0.000	0.998	0.001
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.998	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.998	0.000
R26.1 Paralytic gait	0.000	0.998	0.001
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.001
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.998	0.001
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.001
Z76.5 Malingerer [conscious situation]	0.000	0.998	0.001
Z76.4 Other boarder in health-care facility	0.000	0.998	0.001
Z76.2 Health supervision and care of other healthy infant and child	0.000	0.998	0.001
Z76.1 Health supervision and care of foundling	0.000	0.998	0.001
Z76.0 Issue of repeat prescription	0.000	0.998	0.001
G20 Parkinson's disease	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.000	0.998	0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.001
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.998	0.001
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.998	0.001
Z75.0 Medical services not available in home	0.000	0.998	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.001
H57.0 Anomalies of pupillary function	0.000	0.998	0.001
Z76.8 Persons encountering health services in other specified circumstances	0.000	0.998	0.001
S72.10 Pertrochanteric fracture (closed)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
K12.1 Other forms of stomatitis	0.000	0.999	0.001
H57 Other disorders of eye and adnexa	0.000	0.999	0.001
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.999	0.001
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.999	0.001
N76.5 Ulceration of vagina	0.000	0.999	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.999	0.001
Z70.9 Sex counselling, unspecified	0.000	0.999	0.001
Z70.8 Other sex counselling	0.000	0.999	0.001
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.000	0.999	0.001
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.000	0.999	0.001
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.000	0.999	0.001
Z70.0 Counselling related to sexual attitude	0.000	0.999	0.001
Z75.2 Other waiting period for investigation and treatment	0.000	0.999	0.001
Z73 Problems related to life-management difficulty	0.000	0.999	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.999	0.001
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.999	0.001
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.999	0.001
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.999	0.001
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.999	0.001
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.999	0.001
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.999	0.001
M35.0 Sicca syndrome [Sjogren]	0.000	0.999	0.001
O80.8 Other single spontaneous delivery	0.001	0.999	0.000
S62.5 Fracture of thumb	0.000	0.999	0.001
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.999	0.001
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
R17 Unspecified jaundice	0.000	0.999	0.001
N76.6 Ulceration of vulva	0.000	0.999	0.001
R25.3 Fasciculation	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
Z74.0 Reduced mobility	0.000	0.999	0.001
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.999	0.001
K82.1 Hydrops of gallbladder	0.000	0.999	0.001
M85.9 Disorder of bone density and structure, unspecified	0.000	0.999	0.001
M85.5 Aneurysmal bone cyst	0.000	0.999	0.001
M85.4 Solitary bone cyst	0.000	0.999	0.001
M85.3 Osteitis condensans	0.000	0.999	0.001
M85.2 Hyperostosis of skull	0.000	0.999	0.001
M85.1 Skeletal fluorosis	0.000	0.999	0.001
Y83.9 Surgical procedure, unspecified	0.001	0.999	0.000
Z73.8 Other problems related to life-management difficulty	0.000	0.999	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.999	0.001
C67.4 Posterior wall of bladder	0.001	0.999	0.000
K29.1 Other acute gastritis	0.001	0.999	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.999	0.001
M83 Adult osteomalacia	0.000	0.999	0.001
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.999	0.001
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.999	0.001
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.999	0.001
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.999	0.001
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.999	0.001
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.999	0.001
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.999	0.001
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.999	0.001
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.999	0.001
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
K05.6 Periodontal disease, unspecified	0.001	0.999	0.000
R25.0 Abnormal head movements	0.000	0.999	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
D38.1 Trachea, bronchus and lung	0.001	0.999	0.000
I51.4 Myocarditis, unspecified	0.000	0.999	0.001
M81.9 Osteoporosis, unspecified	0.000	0.999	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
C67.1 Dome of bladder	0.001	0.999	0.000
L40.0 Psoriasis vulgaris	0.000	0.999	0.001
Z73.6 Limitation of activities due to disability	0.000	0.999	0.001
Z73.5 Social role conflict, not elsewhere classified	0.000	0.999	0.001
Z73.4 Inadequate social skills, not elsewhere classified	0.000	0.999	0.001
Z73.2 Lack of relaxation and leisure	0.000	0.999	0.001
Z73.1 Accentuation of personality traits	0.000	0.999	0.001
Z73.0 Burn-out	0.000	0.999	0.001
M81 Osteoporosis without pathological fracture	0.000	0.999	0.001
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.999	0.001
N76.3 Subacute and chronic vulvitis	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.999	0.001
M85.18 Skeletal fluorosis (Other)	0.000	0.999	0.001
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.999	0.001
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.999	0.001
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.999	0.001
M85.14 Skeletal fluorosis (Hand)	0.000	0.999	0.001
M85.13 Skeletal fluorosis (Forearm)	0.000	0.999	0.001
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.999	0.001
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.999	0.001
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.999	0.001
M85.29 Hyperostosis of skull-Site unspec	0.000	0.999	0.001
M85.28 Hyperostosis of skull-Other	0.000	0.999	0.001
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.999	0.001
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.999	0.001
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.999	0.001
M85.24 Hyperostosis of skull-Hand	0.000	0.999	0.001
M85.23 Hyperostosis of skull-Forearm	0.000	0.999	0.001
M85.22 Hyperostosis of skull-Upper arm	0.000	0.999	0.001
M85.21 Hyperostosis of skull-Shldr region	0.000	0.999	0.001
M85.20 Hyperostosis of skull-Mult sites	0.000	0.999	0.001
M85.39 Osteitis condensans (Site unspecified)	0.000	0.999	0.001
M85.38 Osteitis condensans (Other)	0.000	0.999	0.001
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.999	0.001
M85.36 Osteitis condensans (Lower leg)	0.000	0.999	0.001
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.999	0.001
M85.34 Osteitis condensans (Hand)	0.000	0.999	0.001
M85.33 Osteitis condensans (Forearm)	0.000	0.999	0.001
M85.32 Osteitis condensans (Upper arm)	0.000	0.999	0.001
M85.31 Osteitis condensans (Shoulder region)	0.000	0.999	0.001
M85.30 Osteitis condensans (Multiple sites)	0.000	0.999	0.001
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.999	0.001
M85.48 Solitary bone cyst (Other)	0.000	0.999	0.001
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.999	0.001
M85.46 Solitary bone cyst (Lower leg)	0.000	0.999	0.001
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.999	0.001
M85.44 Solitary bone cyst (Hand)	0.000	0.999	0.001
M85.43 Solitary bone cyst (Forearm)	0.000	0.999	0.001
M85.42 Solitary bone cyst (Upper arm)	0.000	0.999	0.001
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.999	0.001
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.999	0.001
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.999	0.001
M85.58 Aneurysmal bone cyst (Other)	0.000	0.999	0.001
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.999	0.001
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.999	0.001
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.999	0.001
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.999	0.001
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.999	0.001
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.999	0.001
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.999	0.001
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.999	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.999	0.001
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.999	0.001
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.999	0.001
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.999	0.001
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.999	0.001
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.999	0.001
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.999	0.001
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.999	0.001
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.999	0.001
Z75.5 Holiday relief care	0.000	0.999	0.001
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
M35.3 Polymyalgia rheumatica	0.000	0.999	0.001
N70.1 Chronic salpingitis and oophoritis	0.001	0.999	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.999	0.001
R27 Other lack of coordination	0.000	0.999	0.001
J84.9 Interstitial pulmonary disease, unspecified	0.001	0.999	0.000
M83.9 Adult osteomalacia, unspecified	0.000	0.999	0.001
M83.8 Other adult osteomalacia	0.000	0.999	0.001
M83.5 Other drug-induced osteomalacia in adults	0.000	0.999	0.001
M83.4 Aluminum bone disease	0.000	0.999	0.001
M83.3 Adult osteomalacia due to malnutrition	0.000	0.999	0.001
M83.2 Adult osteomalacia due to malabsorption	0.000	0.999	0.001
M83.1 Senile osteomalacia	0.000	0.999	0.001
M83.0 Puerperal osteomalacia	0.000	0.999	0.001
M85.6 Other cyst of bone	0.000	0.999	0.001
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
S90.0 Contusion of ankle	0.001	0.999	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.001	0.999	0.000
H30-H36 Disorders of choroid and retina	0.001	0.999	0.000
C77.5 Intrapelvic lymph nodes	0.001	0.999	0.000
H54.5 Low vision, one eye	0.001	0.999	0.000
N87.0 Mild cervical dysplasia	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.001	0.999	0.000
Z34.8 Supervision of other normal pregnancy	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.999	0.001
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.999	0.001
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.999	0.001
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.999	0.001
C67.3 Anterior wall of bladder	0.001	0.999	0.000
D35.2 Pituitary gland	0.000	0.999	0.001
M81.8 Other osteoporosis	0.000	0.999	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.999	0.001
M81.5 Idiopathic osteoporosis	0.000	0.999	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.999	0.001
M81.1 Postoophorectomy osteoporosis	0.000	0.999	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.999	0.001
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.999	0.001
K82 Other diseases of gallbladder	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.000	0.999	0.001
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.001	0.999	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.999	0.001
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.999	0.001
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
H30 Chorioretinal inflammation	0.001	0.999	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.999	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.999	0.001
M83.08 Puerperal osteomalacia (Other)	0.000	0.999	0.001
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.999	0.001
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations