TreeWAS – Variant ID: rs12933472

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I73.9 Peripheral vascular disease, unspecified	0.031	0.969	0.000
I73 Other peripheral vascular diseases	0.025	0.975	0.000
I77.8 Other specified disorders of arteries and arterioles	0.024	0.976	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.023	0.977	0.000
I77 Other disorders of arteries and arterioles	0.023	0.977	0.000
I74 Arterial embolism and thrombosis	0.022	0.978	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.021	0.979	0.000
I77.6 Arteritis, unspecified	0.020	0.980	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.018	0.982	0.000
H18.8 Other specified disorders of cornea	0.018	0.982	0.000
I70 Atherosclerosis	0.018	0.982	0.000
H18 Other disorders of cornea	0.017	0.983	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.017	0.983	0.000
H18.5 Hereditary corneal dystrophies	0.017	0.983	0.000
I71 Aortic aneurysm and dissection	0.017	0.983	0.000
I72 Other aneurysm	0.017	0.983	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.017	0.983	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.017	0.983	0.000
I73.0 Raynaud's syndrome	0.017	0.983	0.000
I77.5 Necrosis of artery	0.016	0.983	0.000
I77.4 Coeliac artery compression syndrome	0.016	0.983	0.000
I77.3 Arterial fibromuscular dysplasia	0.016	0.983	0.000
I77.2 Rupture of artery	0.016	0.983	0.000
I74.8 Embolism and thrombosis of other arteries	0.016	0.984	0.000
I74.5 Embolism and thrombosis of iliac artery	0.016	0.984	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.016	0.984	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.016	0.984	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.016	0.984	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.016	0.984	0.000
H18.9 Disorder of cornea, unspecified	0.015	0.985	0.000
I70.1 Atherosclerosis of renal artery	0.015	0.985	0.000
I73.8 Other specified peripheral vascular diseases	0.014	0.986	0.000
H18.2 Other corneal oedema	0.014	0.986	0.000
I72.3 Aneurysm of iliac artery	0.014	0.986	0.000
I77.0 Arteriovenous fistula, acquired	0.014	0.986	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.014	0.986	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.013	0.987	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.013	0.987	0.000
I70.9 Generalised and unspecified atherosclerosis	0.013	0.987	0.000
I70.8 Atherosclerosis of other arteries	0.013	0.987	0.000
H18.7 Other corneal deformities	0.013	0.987	0.000
H18.3 Changes in corneal membranes	0.013	0.987	0.000
H18.0 Corneal pigmentations and deposits	0.013	0.987	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.013	0.987	0.000
I79.1 Aortitis in diseases classified elsewhere	0.013	0.987	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.013	0.987	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.013	0.987	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.013	0.987	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.013	0.987	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.012	0.987	0.000
I72.0 Aneurysm of carotid artery	0.012	0.987	0.000
I70.0 Atherosclerosis of aorta	0.012	0.987	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.012	0.987	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.012	0.987	0.000
I72.2 Aneurysm of renal artery	0.012	0.987	0.000
I72.1 Aneurysm of artery of upper extremity	0.012	0.987	0.000
I72.8 Aneurysm of other specified arteries	0.012	0.988	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.012	0.988	0.000
H18.1 Bullous keratopathy	0.012	0.988	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.012	0.988	0.000
I78 Diseases of capillaries	0.012	0.988	0.000
I72.9 Aneurysm of unspecified site	0.012	0.988	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.012	0.988	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.011	0.988	0.000
H16 Keratitis	0.011	0.989	0.000
I71.0 Dissection of aorta [any part]	0.011	0.989	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.011	0.989	0.000
H18.6 Keratoconus	0.011	0.989	0.000
I72.4 Aneurysm of artery of lower extremity	0.011	0.989	0.000
H15 Disorders of sclera	0.011	0.989	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.011	0.989	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.010	0.990	0.000
H16.0 Corneal ulcer	0.010	0.990	0.000
I77.1 Stricture of artery	0.010	0.990	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.990	0.010
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.010	0.990	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.009	0.990	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.009	0.990	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.009	0.990	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.009	0.990	0.000
H16.2 Keratoconjunctivitis	0.009	0.991	0.000
H18.4 Corneal degeneration	0.009	0.991	0.000
K75.8 Other specified inflammatory liver diseases	0.009	0.991	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.009	0.991	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.991	0.009
H15.8 Other disorders of sclera	0.009	0.991	0.000
I78.8 Other diseases of capillaries	0.009	0.991	0.000
I78.9 Disease of capillaries, unspecified	0.009	0.991	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.009	0.991	0.000
K75 Other inflammatory liver diseases	0.009	0.991	0.000
H16.9 Keratitis, unspecified	0.009	0.991	0.000
K75.9 Inflammatory liver disease, unspecified	0.009	0.991	0.000
H15.1 Episcleritis	0.009	0.991	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.009	0.991	0.000
H20 Iridocyclitis	0.009	0.991	0.000
H16.8 Other keratitis	0.008	0.991	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.008	0.991	0.000
H16.4 Corneal neovascularisation	0.008	0.992	0.000
H16.3 Interstitial and deep keratitis	0.008	0.992	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.008	0.992	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.008	0.992	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.008	0.992	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.008	0.992	0.000
H15.9 Disorder of sclera, unspecified	0.008	0.992	0.000
H15.0 Scleritis	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.008	0.992	0.000
H17 Corneal scars and opacities	0.008	0.992	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.008	0.992	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.008	0.992	0.000
K75.0 Abscess of liver	0.008	0.992	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.007	0.993	0.000
H20.0 Acute and subacute iridocyclitis	0.007	0.993	0.000
K75.4 Autoimmune hepatitis	0.007	0.993	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.007	0.993	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
K75.2 Nonspecific reactive hepatitis	0.007	0.993	0.000
K75.1 Phlebitis of portal vein	0.007	0.993	0.000
H20.2 Lens-induced iridocyclitis	0.006	0.993	0.000
H20.1 Chronic iridocyclitis	0.006	0.994	0.000
H17.1 Other central corneal opacity	0.006	0.994	0.000
H17.0 Adherent leukoma	0.006	0.994	0.000
H17.8 Other corneal scars and opacities	0.005	0.994	0.000
Y57 Other and unspecified drugs and medicaments	0.006	0.994	0.000
H20.8 Other iridocyclitis	0.005	0.994	0.000
H20.9 Iridocyclitis, unspecified	0.006	0.994	0.000
H21 Other disorders of iris and ciliary body	0.005	0.995	0.000
Y57.5 X-ray contrast media	0.005	0.995	0.000
G51.0 Bell's palsy	0.005	0.995	0.000
H17.9 Corneal scar and opacity, unspecified	0.005	0.995	0.000
Y57.8 Other drugs and medicaments	0.005	0.995	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.004	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.996	0.000
Y57.6 Other diagnostic agents	0.004	0.996	0.000
Y57.4 Pharmaceutical excipients	0.004	0.996	0.000
Y57.3 Alcohol deterrents	0.004	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
Y57.1 Lipotropic drugs	0.004	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.996	0.000
H21.4 Pupillary membranes	0.004	0.996	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.004	0.996	0.000
H21.2 Degeneration of iris and ciliary body	0.004	0.996	0.000
D23.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.996	0.001
Y40.0 Penicillins	0.000	0.996	0.004
H21.8 Other specified disorders of iris and ciliary body	0.003	0.996	0.000
D73.0 Hyposplenism	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
H21.0 Hyphaema	0.003	0.996	0.001
N60.0 Solitary cyst of breast	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
H02.8 Other specified disorders of eyelid	0.003	0.997	0.000
D35.1 Parathyroid gland	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
Z02.9 Examination for administrative purposes, unspecified	0.000	0.997	0.003
Z02.7 Issue of medical certificate	0.000	0.997	0.003
Z02.6 Examination for insurance purposes	0.000	0.997	0.003
Z02.5 Examination for participation in sport	0.000	0.997	0.003
Z02.4 Examination for driving licence	0.000	0.997	0.003
Z02.3 Examination for recruitment to armed forces	0.000	0.997	0.003
Z02.2 Examination for admission to residential institution	0.000	0.997	0.003
Z02.1 Pre-employment examination	0.000	0.997	0.003
Z02.0 Examination for admission to educational institution	0.000	0.997	0.003
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.997	0.001
S40.0 Contusion of shoulder and upper arm	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
Y83.3 Surgical operation with formation of external stoma	0.003	0.997	0.000
Z48.0 Attention to surgical dressings and sutures	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.003	0.997	0.000
C01 Malignant neoplasm of base of tongue	0.003	0.997	0.000
C71.4 Occipital lobe	0.002	0.997	0.000
C71.8 Overlapping lesion of brain	0.002	0.997	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.003	0.997	0.000
C71.7 Brain stem	0.002	0.997	0.000
C71.6 Cerebellum	0.002	0.997	0.000
C71.5 Cerebral ventricle	0.002	0.997	0.000
F40.2 Specific (isolated) phobias	0.000	0.997	0.002
S42.1 Fracture of scapula	0.002	0.997	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
G51 Facial nerve disorders	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S40 Superficial injury of shoulder and upper arm	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
G51.3 Clonic hemifacial spasm	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
B37.0 Candidal stomatitis	0.002	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.998	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
G51.4 Facial myokymia	0.002	0.998	0.000
G51.2 Melkersson's syndrome	0.002	0.998	0.000
G51.1 Geniculate ganglionitis	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y40 Systemic antibiotics	0.001	0.998	0.001
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
G51.9 Disorder of facial nerve, unspecified	0.002	0.998	0.000
K29.2 Alcoholic gastritis	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
C05 Malignant neoplasm of palate	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
C05.1 Soft palate	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
G51.8 Other disorders of facial nerve	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
C05.0 Hard palate	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
C05.9 Palate, unspecified	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
D32.1 Spinal meninges	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.001	0.998	0.001
Y40.6 Rifamycins	0.001	0.998	0.001
Y40.5 Aminoglycosides	0.001	0.998	0.001
Y40.4 Tetracyclines	0.001	0.998	0.001
Y40.2 Chloramphenicol group	0.001	0.998	0.001
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
C05.8 Overlapping lesion of palate	0.001	0.998	0.000
C05.2 Uvula	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
G20 Parkinson's disease	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.001	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y54.7 Agents affecting calcification	0.001	0.998	0.000
L40 Psoriasis	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
D26.9 Uterus, unspecified	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
Y54.5 Other diuretics	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
S90.0 Contusion of ankle	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
D73.1 Hypersplenism	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.998	0.000
S93.1 Dislocation of toe(s)	0.001	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.001	0.998	0.000
C13 Malignant neoplasm of hypopharynx	0.001	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.001	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
Y40.3 Macrolides	0.001	0.998	0.001
Y58.0 BCG vaccine	0.001	0.998	0.000
C04 Malignant neoplasm of floor of mouth	0.001	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Z88.5 Personal history of allergy to narcotic agent	0.002	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
L40.8 Other psoriasis	0.001	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.998	0.000
Y43 Primarily systemic agents	0.001	0.998	0.000
C09.8 Overlapping lesion of tonsil	0.001	0.999	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.001	0.999	0.000
C09.0 Tonsillar fossa	0.001	0.999	0.000
K38.1 Appendicular concretions	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.999	0.000
Y41.4 Anthelminthics	0.001	0.999	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.999	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.999	0.000
Y41.1 Antimycobacterial drugs	0.001	0.999	0.000
Y41.0 Sulphonamides	0.001	0.999	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
Y59.0 Viral vaccines	0.001	0.999	0.000
Y83.6 Removal of other organ (partial) (total)	0.001	0.999	0.000
R82 Other abnormal findings in urine	0.001	0.999	0.000
C13.0 Postcricoid region	0.001	0.999	0.000
D73.9 Disease of spleen, unspecified	0.001	0.999	0.000
D73.4 Cyst of spleen	0.001	0.999	0.000
D73.3 Abscess of spleen	0.001	0.999	0.000
D73.2 Chronic congestive splenomegaly	0.001	0.999	0.000
Q82.2 Mastocytosis	0.001	0.999	0.000
Y41.5 Antiviral drugs	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
C11 Malignant neoplasm of nasopharynx	0.001	0.999	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.001	0.999	0.000
C03 Malignant neoplasm of gum	0.001	0.999	0.000
C00 Malignant neoplasm of lip	0.001	0.999	0.000
C12 Malignant neoplasm of pyriform sinus	0.001	0.999	0.000
S48 Traumatic amputation of shoulder and upper arm	0.001	0.999	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations