TreeWAS – Variant ID: rs12973620

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65.3 Chronic mucoid otitis media	0.067	0.933	0.000
H65 Nonsuppurative otitis media	0.047	0.953	0.000
H65.4 Other chronic nonsuppurative otitis media	0.045	0.955	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.037	0.963	0.000
H65.1 Other acute nonsuppurative otitis media	0.034	0.966	0.000
H65.0 Acute serous otitis media	0.030	0.970	0.000
H65.2 Chronic serous otitis media	0.025	0.975	0.000
H65-H75 Diseases of middle ear and mastoid	0.012	0.988	0.000
H69 Other disorders of Eustachian tube	0.009	0.991	0.000
H70 Mastoiditis and related conditions	0.009	0.991	0.000
H90 Conductive and sensorineural hearing loss	0.009	0.991	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H68 Eustachian salpingitis and obstruction	0.009	0.991	0.000
H67 Otitis media in diseases classified elsewhere	0.009	0.991	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.009	0.991	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.009	0.991	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.008	0.992	0.000
H73 Other disorders of tympanic membrane	0.008	0.992	0.000
H69.8 Other specified disorders of Eustachian tube	0.008	0.992	0.000
H90-H95 Other disorders of ear	0.008	0.992	0.000
H70.8 Other mastoiditis and related conditions	0.008	0.992	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.008	0.992	0.000
H74 Other disorders of middle ear and mastoid	0.007	0.993	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.007	0.993	0.000
J94.2 Haemothorax	0.007	0.993	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.007	0.993	0.000
H69.0 Patulous Eustachian tube	0.007	0.993	0.000
H90.0 Conductive hearing loss, bilateral	0.007	0.993	0.000
H90.3 Sensorineural hearing loss, bilateral	0.007	0.993	0.000
H70.1 Chronic mastoiditis	0.007	0.993	0.000
Chapter VIII Diseases of the ear and mastoid process	0.007	0.993	0.000
H70.2 Petrositis	0.007	0.993	0.000
H70.0 Acute mastoiditis	0.007	0.993	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.007	0.993	0.000
R01.1 Cardiac murmur, unspecified	0.007	0.993	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.007	0.993	0.000
H92 Otalgia and effusion of ear	0.007	0.993	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.006	0.993	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.006	0.993	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.006	0.993	0.000
H68.1 Obstruction of Eustachian tube	0.006	0.993	0.000
H68.0 Eustachian salpingitis	0.006	0.993	0.000
H73.8 Other specified disorders of tympanic membrane	0.006	0.993	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.993	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.006	0.994	0.000
H69.9 Eustachian tube disorder, unspecified	0.006	0.994	0.000
H73.1 Chronic myringitis	0.006	0.994	0.000
H73.0 Acute myringitis	0.006	0.994	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
H70.9 Mastoiditis, unspecified	0.006	0.994	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.006	0.994	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.006	0.994	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
H92.0 Otalgia	0.006	0.994	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.006	0.994	0.000
H74.1 Adhesive middle ear disease	0.006	0.994	0.000
H74.4 Polyp of middle ear	0.006	0.994	0.000
H93 Other disorders of ear, not elsewhere classified	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
E89.2 Postprocedural hypoparathyroidism	0.006	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.994	0.000
H66.0 Acute suppurative otitis media	0.005	0.994	0.000
H92.2 Otorrhagia	0.005	0.995	0.000
H95.1 Other disorders following mastoidectomy	0.005	0.995	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.005	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
H91 Other hearing loss	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.005	0.995	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.005	0.995	0.000
J94 Other pleural conditions	0.005	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
H93.2 Other abnormal auditory perceptions	0.005	0.995	0.000
S27.0 Traumatic pneumothorax	0.005	0.995	0.000
E89.0 Postprocedural hypothyroidism	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
J94.8 Other specified pleural conditions	0.005	0.995	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.004	0.995	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
Z36.8 Other antenatal screening	0.005	0.995	0.000
H91.2 Sudden idiopathic hearing loss	0.005	0.995	0.000
J94.1 Fibrothorax	0.004	0.995	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
H91.1 Presbycusis	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
H93.0 Degenerative and vascular disorders of ear	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
H91.0 Ototoxic hearing loss	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
I95.1 Orthostatic hypotension	0.004	0.996	0.000
J94.9 Pleural condition, unspecified	0.004	0.996	0.000
J94.0 Chylous effusion	0.004	0.996	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
T91.3 Sequelae of injury of spinal cord	0.004	0.996	0.000
H91.9 Hearing loss, unspecified	0.004	0.996	0.000
H91.3 Deaf mutism, not elsewhere classified	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.004	0.996	0.000
T91.1 Sequelae of fracture of spine	0.004	0.996	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.004	0.996	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.004	0.996	0.000
H93.1 Tinnitus	0.004	0.996	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.996	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.997	0.003
Z45.8 Adjustment and management of other implanted devices	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.003	0.997	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.003	0.997	0.000
T90.5 Sequelae of intracranial injury	0.003	0.997	0.000
Z45 Adjustment and management of implanted device	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
H91.8 Other specified hearing loss	0.003	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
Z45.1 Adjustment and management of infusion pump	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
E89.4 Postprocedural ovarian failure	0.003	0.997	0.000
Z36 Antenatal screening	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.003	0.997	0.000
R63.0 Anorexia	0.000	0.997	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.003	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.997	0.003
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Z45.3 Adjustment and management of implanted hearing device	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.003	0.997	0.000
R01 Cardiac murmurs and other cardiac sounds	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.997	0.003
T90.0 Sequelae of superficial injury of head	0.002	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
O42 Premature rupture of membranes	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.000	0.998	0.002
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
R01.2 Other cardiac sounds	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
K83.0 Cholangitis	0.000	0.998	0.002
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.002	0.998	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.002	0.998	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.002	0.998	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.002	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
R01.0 Benign and innocent cardiac murmurs	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
M77.1 Lateral epicondylitis	0.000	0.998	0.002
Y53.4 Other laxatives	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
W19.9 Unspecified place	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.998	0.002
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
R73 Elevated blood glucose level	0.000	0.998	0.002
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.998	0.001
M77.18 Lateral epicondylitis-Other	0.000	0.998	0.001
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.998	0.001
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.998	0.001
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.998	0.001
M77.14 Lateral epicondylitis-Hand	0.000	0.998	0.001
M77.13 Lateral epicondylitis-Forearm	0.000	0.998	0.001
M77.11 Lateral epicondylitis-Shldr region	0.000	0.998	0.001
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.998	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.001	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.001
D07.5 Prostate	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.001	0.998	0.000
D69.1 Qualitative platelet defects	0.001	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
G93.0 Cerebral cysts	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.001	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
E14.3 With ophthalmic complications	0.002	0.998	0.000
J30.3 Other allergic rhinitis	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
H40.1 Primary open-angle glaucoma	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.998	0.000
T51.0 Ethanol	0.000	0.998	0.002
Z63.0 Problems in relationship with spouse or partner	0.001	0.998	0.000
K83 Other diseases of biliary tract	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.001	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.001	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.998	0.000
D26.9 Uterus, unspecified	0.001	0.998	0.000
H81.2 Vestibular neuronitis	0.001	0.998	0.000
Y46.8 Antispasticity drugs	0.001	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.998	0.000
Y46.5 Valproic acid	0.001	0.998	0.000
Y46.3 Deoxybarbiturates	0.001	0.998	0.000
Y46.1 Oxazolidinediones	0.001	0.998	0.000
Y46.0 Succinimides	0.001	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.999	0.001
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.001	0.999	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.999	0.001
Y48.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.001	0.999	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
N75.1 Abscess of Bartholin's gland	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
Z63.7 Other stressful life events affecting family and household	0.001	0.999	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.999	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.999	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.999	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.999	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.999	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.999	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.999	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.001	0.999	0.000
H61.2 Impacted cerumen	0.001	0.999	0.000
M00.9 Pyogenic arthritis, unspecified	0.000	0.999	0.001
R44.3 Hallucinations, unspecified	0.001	0.999	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.999	0.000
Y48.3 Local anaesthetics	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.001	0.999	0.000
R04.0 Epistaxis	0.001	0.999	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.999	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.999	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
Y47.1 Benzodiazepines	0.001	0.999	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
I38 Endocarditis, valve unspecified	0.000	0.999	0.001
I95 Hypotension	0.001	0.999	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
I95.0 Idiopathic hypotension	0.001	0.999	0.000
K83.5 Biliary cyst	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.999	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.999	0.000
Y47.4 Bromine compounds	0.001	0.999	0.000
Y47.3 Paraldehyde	0.001	0.999	0.000
Y47.2 Chloral derivatives	0.001	0.999	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
Y59.0 Viral vaccines	0.001	0.999	0.000
H60 Otitis externa	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.999	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.001	0.999	0.000
H61.9 Disorder of external ear, unspecified	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.999	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.999	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.999	0.000
Y58.5 Diphtheria vaccine	0.001	0.999	0.000
Y58.4 Tetanus vaccine	0.001	0.999	0.000
Y58.3 Plague vaccine	0.001	0.999	0.000
Y58.2 Cholera vaccine	0.001	0.999	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.999	0.000
Y58.0 BCG vaccine	0.001	0.999	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.999	0.001
H81.0 Meniere's disease	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.999	0.001
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.999	0.001
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.999	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.999	0.001
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations