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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12978748
log Bayes Factor = 5.98606
Chromosome 19   position 52,296,815  (GRCh37) Explore rs12978748 on Ensembl!
Variant rs12978748 is part of Cluster X0101

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M23 Internal derangement of knee
1.000 0.000 0.000
M23.2 Derangement of meniscus due to old tear or injury
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
M15-M19 Arthrosis
0.991 0.009 0.000
M17 Gonarthrosis [arthrosis of knee]
0.990 0.010 0.000
M17.9 Gonarthrosis, unspecified
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.980 0.020 0.000
M06.9 Rheumatoid arthritis, unspecified
0.976 0.024 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
M23.3 Other meniscus derangements
0.958 0.042 0.000
M23.8 Other internal derangements of knee
0.953 0.047 0.000
M80-M85 Disorders of bone density and structure
0.950 0.050 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.944 0.056 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.935 0.065 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.934 0.066 0.000
M24 Other specific joint derangements
0.924 0.076 0.000
M86-M90 Other osteopathies
0.922 0.078 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.907 0.093 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.906 0.094 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.898 0.102 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.895 0.105 0.000
M23.5 Chronic instability of knee
0.888 0.112 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.885 0.115 0.000
M84 Disorders of continuity of bone
0.884 0.116 0.000
M17.5 Other secondary gonarthrosis
0.863 0.137 0.000
M89 Other disorders of bone
0.862 0.138 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.862 0.138 0.000
M17.0 Primary gonarthrosis, bilateral
0.859 0.141 0.000
M23.4 Loose body in knee
0.837 0.163 0.000
M30 Polyarteritis nodosa and related conditions
0.834 0.166 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.834 0.166 0.000
M25.5 Pain in joint
0.832 0.168 0.000
M85 Other disorders of bone density and structure
0.828 0.172 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.828 0.172 0.000
M24.5 Contracture of joint
0.816 0.184 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.815 0.185 0.000
M25.56 Pain in joint (Lower leg)
0.811 0.189 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.809 0.191 0.000
M15 Polyarthrosis
0.804 0.196 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.792 0.208 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.792 0.208 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.789 0.211 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.788 0.212 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.788 0.212 0.000
M25.4 Effusion of joint
0.786 0.214 0.000
M89.9 Disorder of bone, unspecified
0.785 0.215 0.000
M60-M63 Disorders of muscles
0.784 0.216 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.781 0.219 0.000
M91-M94 Chondropathies
0.778 0.222 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.776 0.223 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.775 0.225 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.768 0.232 0.000
M24.7 Protrusio acetabuli
0.766 0.234 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.763 0.237 0.000
M25.51 Pain in joint (Shoulder region)
0.757 0.243 0.000
M17.3 Other posttraumatic gonarthrosis
0.751 0.249 0.000
M00-M03 Infectious arthropathies
0.751 0.249 0.000
M84.0 Malunion of fracture
0.750 0.250 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.747 0.253 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.744 0.256 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.743 0.257 0.000
M06.3 Rheumatoid nodule
0.743 0.257 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.739 0.261 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.735 0.265 0.000
M05 Seropositive rheumatoid arthritis
0.734 0.266 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.733 0.267 0.000
M25.8 Other specified joint disorders
0.733 0.267 0.000
M85.6 Other cyst of bone
0.727 0.273 0.000
M24.1 Other articular cartilage disorders
0.717 0.283 0.000
M23.1 Discoid meniscus (congenital)
0.717 0.283 0.000
M23.0 Cystic meniscus
0.717 0.283 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.716 0.284 0.000
M33 Dermatopolymyositis
0.714 0.285 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.714 0.286 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.710 0.290 0.000
M80 Osteoporosis with pathological fracture
0.708 0.292 0.000
M12 Other specific arthropathies
0.706 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.293 0.000
M08 Juvenile arthritis
0.706 0.293 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.705 0.295 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.297 0.000
M06.2 Rheumatoid bursitis
0.702 0.297 0.000
M06.1 Adult-onset Still's disease
0.702 0.297 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.702 0.298 0.000
M40-M43 Deforming dorsopathies
0.701 0.299 0.000
M10 Gout
0.700 0.300 0.000
M86 Osteomyelitis
0.700 0.300 0.000
M25.3 Other instability of joint
0.700 0.300 0.000
M06.4 Inflammatory polyarthropathy
0.699 0.301 0.000
M34 Systemic sclerosis
0.695 0.305 0.000
M23.9 Internal derangement of knee, unspecified
0.694 0.305 0.000
M25.2 Flail joint
0.693 0.307 0.000
M25.1 Fistula of joint
0.693 0.307 0.000
M90 Osteopathies in diseases classified elsewhere
0.692 0.308 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.692 0.308 0.000
M11 Other crystal arthropathies
0.692 0.308 0.000
M24.51 Contracture of joint (Shoulder region)
0.690 0.310 0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.687 0.313 0.000
M23.37 Other meniscus derangements-Capsular lig
0.687 0.313 0.000
M31 Other necrotising vasculopathies
0.686 0.314 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.684 0.316 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.684 0.316 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.684 0.316 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.684 0.316 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.684 0.316 0.000
M83 Adult osteomalacia
0.681 0.319 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.678 0.322 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.676 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.675 0.325 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.675 0.325 0.000
M24.54 Contracture of joint (Hand)
0.674 0.326 0.000
M87 Osteonecrosis
0.672 0.328 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.669 0.330 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.669 0.330 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.669 0.330 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.669 0.330 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.669 0.330 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.669 0.330 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.669 0.330 0.000
M82 Osteoporosis in diseases classified elsewhere
0.669 0.331 0.000
M89.0 Algoneurodystrophy
0.668 0.332 0.000
M25.46 Effusion of joint (Lower leg)
0.668 0.332 0.000
M24.9 Joint derangement, unspecified
0.662 0.337 0.000
M24.6 Ankylosis of joint
0.662 0.337 0.000
M85.0 Fibrous dysplasia (monostotic)
0.661 0.339 0.000
M25.59 Pain in joint (Site unspecified)
0.659 0.340 0.000
M07 Psoriatic and enteropathic arthropathies
0.659 0.341 0.000
M24.2 Disorder of ligament
0.658 0.342 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.655 0.345 0.000
M84.4 Pathological fracture, not elsewhere classified
0.654 0.346 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.654 0.346 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.653 0.347 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.653 0.347 0.000
M24.0 Loose body in joint
0.652 0.347 0.000
M15.8 Other polyarthrosis
0.651 0.348 0.000
M89.8 Other specified disorders of bone
0.649 0.351 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.649 0.351 0.000
M25.9 Joint disorder, unspecified
0.649 0.351 0.000
M89.3 Hypertrophy of bone
0.648 0.351 0.000
M23.49 Loose body in knee-Unspec lig/men
0.646 0.354 0.000
M22 Disorders of patella
0.645 0.355 0.000
M25.0 Haemarthrosis
0.645 0.355 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.644 0.356 0.000
M17.1 Other primary gonarthrosis
0.643 0.357 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.642 0.358 0.000
M89.5 Osteolysis
0.638 0.361 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.637 0.363 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.637 0.363 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.637 0.363 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.637 0.363 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.637 0.363 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.637 0.363 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.637 0.363 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.635 0.365 0.000
M84.9 Disorder of continuity of bone, unspecified
0.634 0.366 0.000
M84.8 Other disorders of continuity of bone
0.634 0.366 0.000
M84.3 Stress fracture, not elsewhere classified
0.634 0.366 0.000
M84.2 Delayed union of fracture
0.634 0.366 0.000
M21 Other acquired deformities of limbs
0.631 0.369 0.000
M13 Other arthritis
0.626 0.374 0.000
M93 Other osteochondropathies
0.624 0.376 0.000
M06.0 Seronegative rheumatoid arthritis
0.619 0.381 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.618 0.382 0.000
M89.6 Osteopathy after poliomyelitis
0.618 0.382 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.618 0.382 0.000
M89.2 Other disorders of bone development and growth
0.618 0.382 0.000
M89.1 Epiphyseal arrest
0.618 0.382 0.000
M81 Osteoporosis without pathological fracture
0.614 0.386 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.613 0.387 0.000
M84.01 Malunion of fracture (Shoulder region)
0.610 0.389 0.000
M84.02 Malunion of fracture (Upper arm)
0.606 0.393 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.606 0.394 0.000
M23.47 Loose body in knee-Capsular lig
0.600 0.400 0.000
M23.46 Loose body in knee-O/unsp lat men
0.600 0.400 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.600 0.400 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.600 0.400 0.000
M23.43 Loose body in knee-Med lig/oth men
0.600 0.400 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.600 0.400 0.000
M23.40 Loose body in knee-Mult sites
0.600 0.400 0.000
M62 Other disorders of muscle
0.600 0.400 0.000
M25.52 Pain in joint (Upper arm)
0.599 0.401 0.000
M60 Myositis
0.599 0.401 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.598 0.402 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.598 0.402 0.000
M30.2 Juvenile polyarteritis
0.598 0.402 0.000
M30.0 Polyarteritis nodosa
0.598 0.402 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.597 0.403 0.000
M85.9 Disorder of bone density and structure, unspecified
0.594 0.406 0.000
M85.5 Aneurysmal bone cyst
0.594 0.406 0.000
M85.4 Solitary bone cyst
0.594 0.406 0.000
M85.3 Osteitis condensans
0.594 0.406 0.000
M85.2 Hyperostosis of skull
0.594 0.406 0.000
M85.1 Skeletal fluorosis
0.594 0.406 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.591 0.409 0.000
M92 Other juvenile osteochondrosis
0.588 0.412 0.000
M88 Paget's disease of bone [osteitis deformans]
0.586 0.414 0.000
M24.59 Contracture of joint (Site unspecified)
0.585 0.415 0.000
M24.58 Contracture of joint (Other)
0.585 0.415 0.000
M24.57 Contracture of joint (Ankle and foot)
0.585 0.415 0.000
M24.56 Contracture of joint (Lower leg)
0.585 0.415 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.585 0.415 0.000
M24.53 Contracture of joint (Forearm)
0.585 0.415 0.000
M24.52 Contracture of joint (Upper arm)
0.585 0.415 0.000
M24.50 Contracture of joint (Multiple sites)
0.585 0.415 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.584 0.416 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.581 0.419 0.000
M15.9 Polyarthrosis, unspecified
0.577 0.423 0.000
M15.0 Primary generalised (osteo)arthrosis
0.577 0.423 0.000
M15.4 Erosive (osteo)arthrosis
0.577 0.423 0.000
M15.3 Secondary multiple arthrosis
0.577 0.423 0.000
M15.1 Heberden's nodes (with arthropathy)
0.577 0.423 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.576 0.424 0.000
M50-M54 Other dorsopathies
0.576 0.424 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.573 0.426 0.000
M00 Pyogenic arthritis
0.573 0.427 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.571 0.429 0.000
M25.58 Pain in joint (Other)
0.571 0.429 0.000
M65-M68 Disorders of synovium and tendon
0.569 0.431 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.565 0.435 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.565 0.435 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.565 0.435 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.564 0.436 0.000
M25.49 Effusion of joint (Site unspecified)
0.564 0.436 0.000
M25.48 Effusion of joint (Other)
0.564 0.436 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.564 0.436 0.000
M25.44 Effusion of joint (Hand)
0.564 0.436 0.000
M25.43 Effusion of joint (Forearm)
0.564 0.436 0.000
M25.42 Effusion of joint (Upper arm)
0.564 0.436 0.000
M25.41 Effusion of joint (Shoulder region)
0.564 0.436 0.000
M25.40 Effusion of joint (Multiple sites)
0.564 0.436 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.563 0.437 0.000
M89.98 Disorder of bone, unspecified (Other)
0.563 0.437 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.563 0.437 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.563 0.437 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.563 0.437 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.563 0.437 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.562 0.438 0.000
M61 Calcification and ossification of muscle
0.562 0.438 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.561 0.439 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.558 0.442 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.553 0.447 0.000
M24.79 Protrusio acetabuli-Site unspec
0.549 0.450 0.000
M24.78 Protrusio acetabuli-Other
0.549 0.450 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.549 0.450 0.000
M24.76 Protrusio acetabuli-Lower leg
0.549 0.450 0.000
M24.74 Protrusio acetabuli-Hand
0.549 0.450 0.000
M24.73 Protrusio acetabuli-Forearm
0.549 0.450 0.000
M24.72 Protrusio acetabuli-Upper arm
0.549 0.450 0.000
M24.71 Protrusio acetabuli-Shldr region
0.549 0.450 0.000
M24.70 Protrusio acetabuli-Mult sites
0.549 0.450 0.000
M25.36 Other instability of joint (Lower leg)
0.548 0.452 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.547 0.453 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.547 0.453 0.000
M85.8 Other specified disorders of bone density and structure
0.545 0.455 0.000
M41 Scoliosis
0.543 0.457 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.542 0.457 0.000
M25.47 Effusion of joint (Ankle and foot)
0.542 0.458 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.541 0.459 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.541 0.459 0.000
M86.9 Osteomyelitis, unspecified
0.541 0.459 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.538 0.462 0.000
M02 Reactive arthropathies
0.538 0.462 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.538 0.462 0.000
M25.86 Other specified joint disorders (Lower leg)
0.538 0.462 0.000
M84.09 Malunion of fracture (Site unspecified)
0.538 0.462 0.000
M84.08 Malunion of fracture (Other)
0.538 0.462 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.538 0.462 0.000
M84.06 Malunion of fracture (Lower leg)
0.538 0.462 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.538 0.462 0.000
M84.04 Malunion of fracture (Hand)
0.538 0.462 0.000
M84.00 Malunion of fracture (Multiple sites)
0.538 0.462 0.000
M13.0 Polyarthritis, unspecified
0.536 0.464 0.000
M31.3 Wegener's granulomatosis
0.534 0.465 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.533 0.466 0.000
M18 Arthrosis of first carpometacarpal joint
0.533 0.467 0.000
M84.03 Malunion of fracture (Forearm)
0.533 0.467 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.533 0.467 0.000
M06.38 Rheumatoid nodule (Other)
0.533 0.467 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.533 0.467 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.533 0.467 0.000
M06.33 Rheumatoid nodule (Forearm)
0.533 0.467 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.533 0.467 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.533 0.467 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.533 0.467 0.000
M51 Other intervertebral disk disorders
0.528 0.472 0.000
M90.7 Fracture of bone in neoplastic disease
0.528 0.472 0.000
M05.8 Other seropositive rheumatoid arthritis
0.526 0.474 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.526 0.474 0.000
M05.2 Rheumatoid vasculitis
0.526 0.474 0.000
M05.1 Rheumatoid lung disease
0.526 0.474 0.000
M05.0 Felty's syndrome
0.526 0.474 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.526 0.474 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.526 0.474 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.526 0.474 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.526 0.474 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.526 0.474 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.526 0.474 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.526 0.474 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.526 0.474 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.526 0.474 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.525 0.475 0.000
M25.88 Other specified joint disorders (Other)
0.525 0.475 0.000
M25.83 Other specified joint disorders (Forearm)
0.525 0.475 0.000
M25.82 Other specified joint disorders (Upper arm)
0.525 0.475 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.525 0.475 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.525 0.475 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.524 0.475 0.000
M06.34 Rheumatoid nodule (Hand)
0.522 0.478 0.000
M85.69 Other cyst of bone (Site unspecified)
0.521 0.478 0.000
M85.68 Other cyst of bone (Other)
0.521 0.478 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.521 0.478 0.000
M85.66 Other cyst of bone (Lower leg)
0.521 0.478 0.000
M85.64 Other cyst of bone (Hand)
0.521 0.478 0.000
M85.63 Other cyst of bone (Forearm)
0.521 0.478 0.000
M85.62 Other cyst of bone (Upper arm)
0.521 0.478 0.000
M85.61 Other cyst of bone (Shoulder region)
0.521 0.478 0.000
M85.60 Other cyst of bone (Multiple sites)
0.521 0.478 0.000
M94 Other disorders of cartilage
0.515 0.484 0.000
M21.0 Valgus deformity, not elsewhere classified
0.515 0.485 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.514 0.485 0.000
M24.18 Other articular cartilage disorders (Other)
0.514 0.485 0.000
M24.14 Other articular cartilage disorders (Hand)
0.514 0.485 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.514 0.485 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.514 0.485 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.514 0.485 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.514 0.486 0.000
M23.07 Cystic meniscus-Capsular lig
0.514 0.486 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.514 0.486 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.514 0.486 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.514 0.486 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.514 0.486 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.514 0.486 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.514 0.486 0.000
M23.00 Cystic meniscus (Multiple sites)
0.514 0.486 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.514 0.486 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.514 0.486 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.514 0.486 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.514 0.486 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.514 0.486 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.514 0.486 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.514 0.486 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.514 0.486 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.514 0.486 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.514 0.486 0.000
M32.8 Other forms of systemic lupus erythematosus
0.514 0.486 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.514 0.486 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.514 0.486 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.514 0.486 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.514 0.486 0.000
M36.3 Arthropathy in other blood disorders
0.514 0.486 0.000
M36.2 Haemophilic arthropathy
0.514 0.486 0.000
M36.1 Arthropathy in neoplastic disease
0.514 0.486 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.514 0.486 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.513 0.486 0.000
M93.9 Osteochondropathy, unspecified
0.513 0.487 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.513 0.487 0.000
M33.9 Dermatopolymyositis, unspecified
0.512 0.488 0.000
M33.2 Polymyositis
0.512 0.488 0.000
M33.0 Juvenile dermatomyositis
0.512 0.488 0.000
M24.01 Loose body in joint (Shoulder region)
0.510 0.489 0.000
M33.1 Other dermatomyositis
0.510 0.490 0.000
M80.8 Other osteoporosis with pathological fracture
0.508 0.492 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.508 0.492 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.508 0.492 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.508 0.492 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.508 0.492 0.000
M08.9 Juvenile arthritis, unspecified
0.506 0.493 0.000
M08.8 Other juvenile arthritis
0.506 0.493 0.000
M08.4 Pauciarticular juvenile arthritis
0.506 0.493 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.506 0.493 0.000
M08.2 Juvenile arthritis with systemic onset
0.506 0.493 0.000
M08.1 Juvenile ankylosing spondylitis
0.506 0.493 0.000
M08.0 Juvenile rheumatoid arthritis
0.506 0.493 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.506 0.493 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.506 0.493 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.506 0.493 0.000
M09.0 Juvenile arthritis in psoriasis
0.506 0.493 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.506 0.493 0.000
M12.5 Traumatic arthropathy
0.506 0.493 0.000
M12.4 Intermittent hydrarthrosis
0.506 0.493 0.000
M12.3 Palindromic rheumatism
0.506 0.493 0.000
M12.2 Villonodular synovitis (pigmented)
0.506 0.493 0.000
M12.1 Kaschin-Beck disease
0.506 0.493 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.506 0.493 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.504 0.496 0.000
M06.18 Adult-onset Still's disease (Other)
0.504 0.496 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.504 0.496 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.504 0.496 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.504 0.496 0.000
M06.14 Adult-onset Still's disease (Hand)
0.504 0.496 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.504 0.496 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.504 0.496 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.504 0.496 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.504 0.496 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.504 0.496 0.000
M06.28 Rheumatoid bursitis (Other)
0.504 0.496 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.504 0.496 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.504 0.496 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.504 0.496 0.000
M06.24 Rheumatoid bursitis (Hand)
0.504 0.496 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.504 0.496 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.504 0.496 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.504 0.496 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.504 0.496 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.504 0.496 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.504 0.496 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.504 0.496 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.504 0.496 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.504 0.496 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.504 0.496 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.504 0.496 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.504 0.496 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.504 0.496 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.504 0.496 0.000
M25.31 Other instability of joint (Shoulder region)
0.503 0.497 0.000
M42 Spinal osteochondrosis
0.503 0.497 0.000
M40 Kyphosis and lordosis
0.503 0.497 0.000
M10.4 Other secondary gout
0.502 0.498 0.000
M10.3 Gout due to impairment of renal function
0.502 0.498 0.000
M10.2 Drug-induced gout
0.502 0.498 0.000
M10.1 Lead-induced gout
0.502 0.498 0.000
M10.0 Idiopathic gout
0.502 0.498 0.000
M86.8 Other osteomyelitis
0.502 0.498 0.000
M86.6 Other chronic osteomyelitis
0.502 0.498 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.502 0.498 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.502 0.498 0.000
M86.3 Chronic multifocal osteomyelitis
0.502 0.498 0.000
M86.2 Subacute osteomyelitis
0.502 0.498 0.000
M86.1 Other acute osteomyelitis
0.502 0.498 0.000
M86.0 Acute haematogenous osteomyelitis
0.502 0.498 0.000
M25.39 Other instability of joint (Site unspecified)
0.502 0.498 0.000
M25.38 Other instability of joint (Other)
0.502 0.498 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.502 0.498 0.000
M25.34 Other instability of joint (Hand)
0.502 0.498 0.000
M25.33 Other instability of joint (Forearm)
0.502 0.498 0.000
M25.32 Other instability of joint (Upper arm)
0.502 0.498 0.000
M25.30 Other instability of joint (Multiple sites)
0.502 0.498 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.501 0.499 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.501 0.499 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.501 0.499 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.501 0.499 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.501 0.499 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.501 0.499 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.501 0.499 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.501 0.499 0.000
M22.2 Patellofemoral disorders
0.501 0.499 0.000
M25.50 Pain in joint (Multiple sites)
0.500 0.500 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.499 0.501 0.000
M34.8 Other forms of systemic sclerosis
0.498 0.501 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.498 0.501 0.000
M34.1 CR(E)ST syndrome
0.498 0.501 0.000
M34.0 Progressive systemic sclerosis
0.498 0.501 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.498 0.502 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.498 0.502 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.498 0.502 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.498 0.502 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.498 0.502 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.498 0.502 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.498 0.502 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.498 0.502 0.000
M25.19 Fistula of joint (Site unspecified)
0.497 0.503 0.000
M25.18 Fistula of joint (Other)
0.497 0.503 0.000
M25.17 Fistula of joint (Ankle and foot)
0.497 0.503 0.000
M25.16 Fistula of joint (Lower leg)
0.497 0.503 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.497 0.503 0.000
M25.14 Fistula of joint (Hand)
0.497 0.503 0.000
M25.13 Fistula of joint (Forearm)
0.497 0.503 0.000
M25.12 Fistula of joint (Upper arm)
0.497 0.503 0.000
M25.11 Fistula of joint (Shoulder region)
0.497 0.503 0.000
M25.10 Fistula of joint (Multiple sites)
0.497 0.503 0.000
M25.29 Flail joint (Site unspecified)
0.497 0.503 0.000
M25.28 Flail joint (Other)
0.497 0.503 0.000
M25.27 Flail joint (Ankle and foot)
0.497 0.503 0.000
M25.26 Flail joint (Lower leg)
0.497 0.503 0.000
M25.25 Flail joint (Pelvic region and thigh)
0.497 0.503 0.000
M25.24 Flail joint (Hand)
0.497 0.503 0.000
M25.23 Flail joint (Forearm)
0.497 0.503 0.000
M25.22 Flail joint (Upper arm)
0.497 0.503 0.000
M25.21 Flail joint (Shoulder region)
0.497 0.503 0.000
M25.20 Flail joint (Multiple sites)
0.497 0.503 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.496 0.504 0.000
M90.6 Osteitis deformans in neoplastic disease
0.496 0.504 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.496 0.504 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.496 0.504 0.000
M90.3 Osteonecrosis in caisson disease
0.496 0.504 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.496 0.504 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.496 0.504 0.000
M90.0 Tuberculosis of bone
0.496 0.504 0.000
M11.9 Crystal arthropathy, unspecified
0.496 0.504 0.000
M11.8 Other specified crystal arthropathies
0.496 0.504 0.000
M11.1 Familial chondrocalcinosis
0.496 0.504 0.000
M11.0 Hydroxyapatite deposition disease
0.496 0.504 0.000
M10.9 Gout, unspecified
0.496 0.504 0.000
M22.3 Other derangements of patella
0.496 0.504 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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