TreeWAS – Variant ID: rs12999373

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.5 Other deformities of toe(s) (acquired)	0.000	0.949	0.051
C92 Myeloid leukaemia	0.047	0.953	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.046	0.954	0.000
C91 Lymphoid leukaemia	0.045	0.955	0.000
C81 Hodgkin's disease	0.042	0.958	0.000
C91.1 Chronic lymphocytic leukaemia	0.042	0.958	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.042	0.958	0.000
C92.0 Acute myeloid leukaemia	0.041	0.959	0.000
C92.1 Chronic myeloid leukaemia	0.040	0.960	0.000
C90.0 Multiple myeloma	0.039	0.961	0.000
C92.7 Other myeloid leukaemia	0.039	0.961	0.000
C93 Monocytic leukaemia	0.039	0.961	0.000
C92.5 Acute myelomonocytic leukaemia	0.038	0.962	0.000
C92.9 Myeloid leukaemia, unspecified	0.037	0.963	0.000
C81.0 Lymphocytic predominance	0.037	0.963	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.036	0.964	0.000
C91.0 Acute lymphoblastic leukaemia	0.036	0.964	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.035	0.965	0.000
C95 Leukaemia of unspecified cell type	0.035	0.965	0.000
C92.4 Acute promyelocytic leukaemia	0.035	0.965	0.000
C91.4 Hairy-cell leukaemia	0.035	0.965	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.034	0.966	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.034	0.966	0.000
C92.3 Myeloid sarcoma	0.034	0.966	0.000
C92.2 Subacute myeloid leukaemia	0.034	0.966	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.034	0.966	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.033	0.966	0.000
C94 Other leukaemias of specified cell type	0.033	0.966	0.000
C86 Other specified types of T/NK-cell lymphoma	0.033	0.966	0.000
C93.1 Chronic monocytic leukaemia	0.033	0.967	0.000
C81.9 Hodgkin's disease, unspecified	0.033	0.967	0.000
C91.5 Adult T-cell leukaemia	0.033	0.967	0.000
C81.1 Nodular sclerosis	0.033	0.967	0.000
C81.7 Other Hodgkin's disease	0.032	0.968	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.032	0.968	0.000
C91.7 Other lymphoid leukaemia	0.032	0.968	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.032	0.968	0.000
C91.3 Prolymphocytic leukaemia	0.032	0.968	0.000
C91.2 Subacute lymphocytic leukaemia	0.032	0.968	0.000
C91.9 Lymphoid leukaemia, unspecified	0.032	0.968	0.000
C90.1 Plasma cell leukaemia	0.031	0.968	0.000
C88 Malignant immunoproliferative diseases	0.031	0.969	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.030	0.969	0.000
C81.3 Lymphocytic depletion	0.030	0.969	0.000
C81.2 Mixed cellularity	0.030	0.969	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.031	0.969	0.000
C90.2 Plasmacytoma, extramedullary	0.030	0.970	0.000
C82.0 Small cleaved cell, follicular	0.030	0.970	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.030	0.970	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.028	0.972	0.000
C93.9 Monocytic leukaemia, unspecified	0.028	0.972	0.000
C93.7 Other monocytic leukaemia	0.028	0.972	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.028	0.972	0.000
C93.2 Subacute monocytic leukaemia	0.028	0.972	0.000
C93.0 Acute monocytic leukaemia	0.028	0.972	0.000
C95.0 Acute leukaemia of unspecified cell type	0.028	0.972	0.000
C84.4 Peripheral T-cell lymphoma	0.027	0.973	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.027	0.973	0.000
C82.6 Cutaneous follicle centre lymphoma	0.026	0.974	0.000
C82.5 Diffuse follicle centre lymphoma	0.026	0.974	0.000
C82.4 Follicular lymphoma grade IIIb	0.026	0.974	0.000
C82.2 Large cell, follicular	0.026	0.974	0.000
K55.0 Acute vascular disorders of intestine	0.026	0.974	0.000
C82.3 Follicular lymphoma grade IIIa	0.026	0.974	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.025	0.974	0.000
C85.0 Lymphosarcoma	0.025	0.974	0.000
C95.7 Other leukaemia of unspecified cell type	0.025	0.975	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.025	0.975	0.000
C90.3 Solitary plasmacytoma	0.025	0.975	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.024	0.976	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.024	0.976	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.024	0.976	0.000
C84.3 Lymphoepithelioid lymphoma	0.024	0.976	0.000
C84.2 T-zone lymphoma	0.024	0.976	0.000
C84.1 Sezary's diease	0.024	0.976	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.024	0.976	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.024	0.976	0.000
C86.4 Blastic NK-cell lymphoma	0.024	0.976	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.024	0.976	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.024	0.976	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.024	0.976	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.024	0.976	0.000
C94.7 Other specified leukaemias	0.024	0.976	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.024	0.976	0.000
C94.5 Acute myelofibrosis	0.024	0.976	0.000
C94.4 Acute panmyelosis	0.024	0.976	0.000
C94.3 Mast cell leukaemia	0.024	0.976	0.000
C94.2 Acute megakaryoblastic leukaemia	0.024	0.976	0.000
C94.1 Chronic erythraemia	0.024	0.976	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.024	0.976	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.024	0.976	0.000
C96.8 Histiocytic sarcoma	0.024	0.976	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.024	0.976	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.024	0.976	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.024	0.976	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.024	0.976	0.000
C96.3 True histiocytic lymphoma	0.024	0.976	0.000
C96.2 Malignant mast cell tumour	0.024	0.976	0.000
C96.1 Malignant histiocytosis	0.024	0.976	0.000
C96.0 Letterer-Siwe disease	0.024	0.976	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.024	0.976	0.000
C84.0 Mycosis fungoides	0.024	0.976	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.024	0.976	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.022	0.978	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.022	0.978	0.000
C88.7 Other malignant immunoproliferative diseases	0.022	0.978	0.000
C88.3 Immunoproliferative small intestinal disease	0.022	0.978	0.000
C88.2 Gamma heavy chain disease	0.022	0.978	0.000
C88.1 Alpha heavy chain disease	0.022	0.978	0.000
C84.5 Other and unspecified T-cell lymphomas	0.022	0.978	0.000
C85.1 B-cell lymphoma, unspecified	0.022	0.978	0.000
C95.9 Leukaemia, unspecified	0.020	0.980	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.020	0.980	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.019	0.981	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.017	0.983	0.000
C83.3 Large cell (diffuse)	0.015	0.985	0.000
C83.6 Undifferentiated (diffuse)	0.012	0.987	0.000
C83.5 Lymphoblastic (diffuse)	0.012	0.987	0.000
C83.4 Immunoblastic (diffuse)	0.012	0.987	0.000
C83.2 Mixed small and large cell (diffuse)	0.012	0.987	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.012	0.988	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.011	0.989	0.000
C83.7 Burkitt's tumour	0.010	0.989	0.000
E14.3 With ophthalmic complications	0.000	0.990	0.010
Y45.0 Opioids and related analgesics	0.010	0.990	0.000
C83.1 Small cleaved cell (diffuse)	0.010	0.990	0.000
K75.9 Inflammatory liver disease, unspecified	0.007	0.993	0.000
Z50.1 Other physical therapy	0.000	0.993	0.007
N42.8 Other specified disorders of prostate	0.000	0.993	0.007
L27.0 Generalised skin eruption due to drugs and medicaments	0.006	0.994	0.000
N84.1 Polyp of cervix uteri	0.006	0.994	0.000
K76.8 Other specified diseases of liver	0.006	0.994	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.006	0.994	0.000
C83.0 Small cell (diffuse)	0.005	0.995	0.001
Q23.1 Congenital insufficiency of aortic valve	0.000	0.995	0.005
D27 Benign neoplasm of ovary	0.000	0.995	0.005
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.005	0.995	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
Y45.2 Propionic acid derivatives	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.004	0.996	0.000
T90.4 Sequelae of injury of eye and orbit	0.004	0.996	0.000
E14 Unspecified diabetes mellitus	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
K75 Other inflammatory liver diseases	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.996	0.004
N70.1 Chronic salpingitis and oophoritis	0.000	0.996	0.004
K76 Other diseases of liver	0.004	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.004	0.996	0.000
K55 Vascular disorders of intestine	0.004	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.004	0.996	0.000
Y45.4 Antirheumatics	0.004	0.996	0.000
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.996	0.004
N42 Other disorders of prostate	0.000	0.996	0.004
K22.4 Dyskinesia of oesophagus	0.004	0.996	0.000
E14.4 With neurological complications	0.000	0.996	0.004
K29.1 Other acute gastritis	0.004	0.996	0.000
E14.6 With other specified complications	0.000	0.996	0.004
E28.2 Polycystic ovarian syndrome	0.000	0.996	0.004
N64.5 Other signs and symptoms in breast	0.004	0.996	0.000
K70 Alcoholic liver disease	0.004	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.996	0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.003	0.997	0.000
E14.5 With peripheral circulatory complications	0.000	0.997	0.003
K55.8 Other vascular disorders of intestine	0.003	0.997	0.000
R45.1 Restlessness and agitation	0.000	0.997	0.003
K70-K77 Diseases of liver	0.003	0.997	0.000
E14.2 Withrenal complications	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
E14.7 With multiple complications	0.000	0.997	0.003
E14.0 With coma	0.000	0.997	0.003
E14.1 With ketoacidosis	0.000	0.997	0.003
D04.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
K75.2 Nonspecific reactive hepatitis	0.003	0.997	0.000
K75.1 Phlebitis of portal vein	0.003	0.997	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.997	0.003
N42.2 Atrophy of prostate	0.000	0.997	0.003
K76.5 Hepatic veno-occlusive disease	0.003	0.997	0.000
K76.4 Peliosis hepatis	0.003	0.997	0.000
K76.3 Infarction of liver	0.003	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
M94.8 Other specified disorders of cartilage	0.003	0.997	0.000
E14.8 With unspecified complications	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K76.1 Chronic passive congestion of liver	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.003	0.997	0.000
N42.3 Dysplasia of prostate	0.000	0.997	0.003
D04 Carcinoma in situ of skin	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.003	0.997	0.000
K55.1 Chronic vascular disorders of intestine	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.997	0.003
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.997	0.003
Q23.4 Hypoplastic left heart syndrome	0.000	0.997	0.003
Q23.3 Congenital mitral insufficiency	0.000	0.997	0.003
Q23.2 Congenital mitral stenosis	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
K75.4 Autoimmune hepatitis	0.003	0.997	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K71 Toxic liver disease	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.997	0.003
M22.8 Other disorders of patella	0.000	0.997	0.003
K77 Liver disorders in diseases classified elsewhere	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
D04.7 Skin of lower limb, including hip	0.003	0.997	0.000
D04.9 Skin, unspecified	0.002	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.997	0.000
Y43.4 Immunosuppressive agents	0.002	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
K73.9 Chronic hepatitis, unspecified	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
K76.6 Portal hypertension	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
N42.0 Calculus of prostate	0.000	0.998	0.002
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
D04.8 Skin of other sites	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.002	0.998	0.000
K71.8 Toxic liver disease with other disorders of liver	0.002	0.998	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.002	0.998	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.002	0.998	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.002	0.998	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.002	0.998	0.000
K71.2 Toxic liver disease with acute hepatitis	0.002	0.998	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.002	0.998	0.000
K71.0 Toxic liver disease with cholestasis	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.998	0.002
O36.2 Maternal care for hydrops foetalis	0.000	0.998	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.000	0.998	0.002
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
D04.5 Skin of trunk	0.002	0.998	0.000
R45.4 Irritability and anger	0.000	0.998	0.002
D04.4 Skin of scalp and neck	0.002	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
K38 Other diseases of appendix	0.002	0.998	0.000
G51.9 Disorder of facial nerve, unspecified	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.998	0.002
N64.9 Disorder of breast, unspecified	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
K01.0 Embedded teeth	0.000	0.998	0.002
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
K38.1 Appendicular concretions	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.002	0.998	0.000
R45.5 Hostility	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
R45.0 Nervousness	0.000	0.998	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
K38.9 Disease of appendix, unspecified	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.002	0.998	0.000
K38.0 Hyperplasia of appendix	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
R45.3 Demoralisation and apathy	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.998	0.002
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
N64 Other disorders of breast	0.002	0.998	0.000
R45.6 Physical violence	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
K38.3 Fistula of appendix	0.002	0.998	0.000
K38.2 Diverticulum of appendix	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.998	0.002
M96.5 Postradiation scoliosis	0.000	0.998	0.002
M96.4 Postsurgical lordosis	0.000	0.998	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.998	0.002
M96.2 Postradiation kyphosis	0.000	0.998	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.002	0.998	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.998	0.002
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.000	0.998	0.002
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
F45 Somatoform disorders	0.002	0.998	0.000
M48.0 Spinal stenosis	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
M48.8 Other specified spondylopathies	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.998	0.002
D37.7 Other digestive organs	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.002
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
O36.9 Maternal care for foetal problem, unspecified	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.001
Y57.5 X-ray contrast media	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.001	0.998	0.000
D37.1 Stomach	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.001	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.998	0.002
N64.3 Galactorrhoea not associated with childbirth	0.001	0.998	0.000
N64.2 Atrophy of breast	0.001	0.998	0.000
N64.0 Fissure and fistula of nipple	0.001	0.998	0.000
M48 Other spondylopathies	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.998	0.000
K74.0 Hepatic fibrosis	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.998	0.001
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.998	0.001
D36.7 Other specified sites	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.001
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.001
Q89.8 Other specified congenital malformations	0.000	0.998	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.001
Q89.4 Conjoined twins	0.000	0.998	0.001
Q89.3 Situs inversus	0.000	0.998	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.001
Q89.0 Congenital malformations of spleen	0.000	0.998	0.001
S13.1 Dislocation of cervical vertebra	0.000	0.998	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.998	0.001
Y58 Bacterial vaccines	0.001	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.001	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.001
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.001	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.001	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.001	0.998	0.000
K74.1 Hepatic sclerosis	0.001	0.998	0.000
M94.3 Chondrolysis	0.001	0.998	0.000
M94.1 Relapsing polychondritis	0.001	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.001	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.001
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
Q26 Congenital malformations of great veins	0.000	0.998	0.001
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.001
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.998	0.001
F45.9 Somatoform disorder, unspecified	0.001	0.999	0.000
F45.2 Hypochondriacal disorder	0.001	0.999	0.000
F45.1 Undifferentiated somatoform disorder	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.999	0.001
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.999	0.001
Q28 Other congenital malformations of circulatory system	0.000	0.999	0.001
M48.05 Spinal stenosis (Thoracolumbar region)	0.001	0.999	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.001	0.999	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
J95.0 Tracheostomy malfunction	0.001	0.999	0.000
M94.9 Disorder of cartilage, unspecified	0.001	0.999	0.000
N64.1 Fat necrosis of breast	0.001	0.999	0.000
Q24.0 Dextrocardia	0.000	0.999	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.999	0.001
Q85 Phakomatoses, not elsewhere classified	0.000	0.999	0.001
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.001	0.999	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.001	0.999	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.001	0.999	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.001	0.999	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.999	0.001
O62.1 Secondary uterine inertia	0.001	0.999	0.000
Q24.6 Congenital heart block	0.000	0.999	0.001
Q24.4 Congenital subaortic stenosis	0.000	0.999	0.001
Q24.3 Pulmonary infundibular stenosis	0.000	0.999	0.001
Q24.2 Cor triatriatum	0.000	0.999	0.001
Q24.1 Levocardia	0.000	0.999	0.001
Q62.8 Other congenital malformations of ureter	0.000	0.999	0.001
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.999	0.001
Q62.6 Malposition of ureter	0.000	0.999	0.001
Q62.4 Agenesis of ureter	0.000	0.999	0.001
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.999	0.001
Q62.2 Congenital megaloureter	0.000	0.999	0.001
Q62.1 Atresia and stenosis of ureter	0.000	0.999	0.001
Q62.0 Congenital hydronephrosis	0.000	0.999	0.001
M25.75 Osteophyte (Pelvic region and thigh)	0.001	0.999	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
F45.4 Persistent somatoform pain disorder	0.001	0.999	0.000
J15.8 Other bacterial pneumonia	0.000	0.999	0.001
R45.2 Unhappiness	0.000	0.999	0.001
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.999	0.001
E28 Ovarian dysfunction	0.000	0.999	0.001
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
J15.5 Pneumonia due to Escherichia coli	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations