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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13046373
log Bayes Factor = <0.0001
Chromosome 21   position 32,060,490  (GRCh37) Explore rs13046373 on Ensembl!
Variant rs13046373 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
X41.9 Unspecified place
0.000 0.977 0.023
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.000 0.983 0.017
H33.3 Retinal breaks without detachment
0.000 0.985 0.015
X40-X49 Accidental poisoning by and exposure to noxious substances
0.000 0.986 0.014
X49.9 Unspecified place
0.000 0.986 0.013
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.000 0.987 0.013
X41.0 Home
0.000 0.987 0.013
X41.8 Other specified place
0.000 0.987 0.013
X41.7 Farm
0.000 0.987 0.013
X41.6 Industrial and construction area
0.000 0.987 0.013
X41.5 Trade and service area
0.000 0.987 0.013
X41.4 Street and highway
0.000 0.987 0.013
X41.3 Sports and athletics area
0.000 0.987 0.013
X41.1 Residential institution
0.000 0.987 0.013
X41.2 School, other institution and public administrative area
0.000 0.988 0.012
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.000 0.988 0.012
X45 Accidental poisoning by and exposure to alcohol
0.000 0.988 0.011
X43.0 Home
0.000 0.989 0.011
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.000 0.989 0.010
X48 Accidental poisoning by and exposure to pesticides
0.000 0.990 0.010
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.000 0.990 0.010
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.000 0.990 0.010
M19.97 Arthrosis, unspecified (Ankle and foot)
0.000 0.990 0.010
S02.30 Fracture of orbital floor (closed)
0.010 0.990 0.000
X45.0 Home
0.000 0.990 0.010
X49.4 Street and highway
0.000 0.990 0.010
X49.0 Home
0.000 0.990 0.010
X49.8 Other specified place
0.000 0.990 0.010
X49.7 Farm
0.000 0.990 0.010
X49.3 Sports and athletics area
0.000 0.990 0.010
X49.2 School, other institution and public administrative area
0.000 0.990 0.010
X49.1 Residential institution
0.000 0.990 0.010
X47 Accidental poisoning by and exposure to other gases and vapours
0.000 0.991 0.009
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.000 0.991 0.009
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities
0.000 0.991 0.009
X49.5 Trade and service area
0.000 0.991 0.009
O26.9 Pregnancy-related condition, unspecified
0.000 0.991 0.009
X43.9 Unspecified place
0.000 0.991 0.009
X43.8 Other specified place
0.000 0.991 0.009
X43.7 Farm
0.000 0.991 0.009
X43.6 Industrial and construction area
0.000 0.991 0.009
X43.5 Trade and service area
0.000 0.991 0.009
X43.4 Street and highway
0.000 0.991 0.009
X43.3 Sports and athletics area
0.000 0.991 0.009
X43.2 School, other institution and public administrative area
0.000 0.991 0.009
X43.1 Residential institution
0.000 0.991 0.009
X49.6 Industrial and construction area
0.000 0.991 0.009
X45.9 Unspecified place
0.000 0.991 0.008
X45.8 Other specified place
0.000 0.991 0.008
X45.7 Farm
0.000 0.991 0.008
X45.6 Industrial and construction area
0.000 0.991 0.008
X45.5 Trade and service area
0.000 0.991 0.008
X45.4 Street and highway
0.000 0.991 0.008
X45.3 Sports and athletics area
0.000 0.991 0.008
X45.2 School, other institution and public administrative area
0.000 0.991 0.008
X45.1 Residential institution
0.000 0.991 0.008
X42.2 School, other institution and public administrative area
0.000 0.992 0.008
X42.9 Unspecified place
0.000 0.992 0.008
X42.0 Home
0.000 0.992 0.008
X42.8 Other specified place
0.000 0.992 0.008
X42.7 Farm
0.000 0.992 0.008
X42.6 Industrial and construction area
0.000 0.992 0.008
X42.5 Trade and service area
0.000 0.992 0.008
X42.4 Street and highway
0.000 0.992 0.008
X42.3 Sports and athletics area
0.000 0.992 0.008
X42.1 Residential institution
0.000 0.992 0.008
X47.9 Unspecified place
0.000 0.992 0.008
X40.9 Unspecified place
0.000 0.992 0.007
X40.0 Home
0.000 0.992 0.007
X40.8 Other specified place
0.000 0.992 0.007
X40.7 Farm
0.000 0.992 0.007
X40.6 Industrial and construction area
0.000 0.992 0.007
X40.5 Trade and service area
0.000 0.992 0.007
X40.4 Street and highway
0.000 0.992 0.007
X40.3 Sports and athletics area
0.000 0.992 0.007
X40.2 School, other institution and public administrative area
0.000 0.992 0.007
X40.1 Residential institution
0.000 0.992 0.007
X46.6 Industrial and construction area
0.000 0.992 0.007
X46.9 Unspecified place
0.000 0.992 0.007
X46.8 Other specified place
0.000 0.992 0.007
X46.7 Farm
0.000 0.992 0.007
X46.5 Trade and service area
0.000 0.992 0.007
X46.4 Street and highway
0.000 0.992 0.007
X46.3 Sports and athletics area
0.000 0.992 0.007
X46.2 School, other institution and public administrative area
0.000 0.992 0.007
X46.1 Residential institution
0.000 0.992 0.007
X46.0 Home
0.000 0.992 0.007
X48.9 Unspecified place
0.000 0.992 0.007
X48.8 Other specified place
0.000 0.992 0.007
X48.7 Farm
0.000 0.992 0.007
X48.6 Industrial and construction area
0.000 0.992 0.007
X48.5 Trade and service area
0.000 0.992 0.007
X48.4 Street and highway
0.000 0.992 0.007
X48.3 Sports and athletics area
0.000 0.992 0.007
X48.2 School, other institution and public administrative area
0.000 0.992 0.007
X48.1 Residential institution
0.000 0.992 0.007
X48.0 Home
0.000 0.992 0.007
O73.0 Retained placenta, without haemorrhage
0.000 0.992 0.008
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity
0.000 0.993 0.007
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities
0.000 0.993 0.007
X47.8 Other specified place
0.000 0.993 0.007
X47.7 Farm
0.000 0.993 0.007
X47.5 Trade and service area
0.000 0.993 0.007
X47.4 Street and highway
0.000 0.993 0.007
X47.3 Sports and athletics area
0.000 0.993 0.007
X47.2 School, other institution and public administrative area
0.000 0.993 0.007
X47.1 Residential institution
0.000 0.993 0.007
R10.0 Acute abdomen
0.000 0.993 0.007
X44.9 Unspecified place
0.000 0.993 0.007
X44.0 Home
0.000 0.993 0.007
X44.8 Other specified place
0.000 0.993 0.007
X44.7 Farm
0.000 0.993 0.007
X44.6 Industrial and construction area
0.000 0.993 0.007
X44.5 Trade and service area
0.000 0.993 0.007
X44.4 Street and highway
0.000 0.993 0.007
X44.3 Sports and athletics area
0.000 0.993 0.007
X44.1 Residential institution
0.000 0.993 0.007
X47.6 Industrial and construction area
0.000 0.993 0.006
X43.99 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system; Unspecified place ;During unspecified activity
0.000 0.993 0.006
X45.99 Accidental poisoning by and exposure to alcohol; Unspecified place ;During unspecified activity
0.000 0.994 0.006
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.006 0.994 0.000
X44.2 School, other institution and public administrative area
0.000 0.994 0.006
X42.08 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified,Home , While engaged in other specified activities
0.000 0.994 0.006
X42.99 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified; Unspecified place ;During unspecified activity
0.000 0.994 0.006
X42.91 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified; Unspecified place ;While engaged in leisure activity
0.000 0.994 0.006
F43.0 Acute stress reaction
0.006 0.994 0.000
X40.09 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics; Home; During unspecified activity
0.000 0.994 0.005
X40.99 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics: Unspecified place: During unspecified activity
0.000 0.994 0.005
X46.69 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours; Industrial and construction area ;During unspecified activity
0.000 0.994 0.005
T79.3 Post-traumatic wound infection, not elsewhere classified
0.000 0.994 0.006
X47.0 Home
0.000 0.994 0.005
I73.9 Peripheral vascular disease, unspecified
0.000 0.994 0.006
S02.3 Fracture of orbital floor
0.005 0.995 0.000
X44.09 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances; Home; During unspecified activity
0.000 0.995 0.005
X44.08 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances; Home; While engaged in other specified activities
0.000 0.995 0.005
X44.99 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances; Unspecified place ;During unspecified activity
0.000 0.995 0.005
T79.6 Traumatic ischaemia of muscle
0.000 0.995 0.005
C45.0 Mesothelioma of pleura
0.005 0.995 0.000
C45.9 Mesothelioma, unspecified
0.005 0.995 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.000 0.995 0.005
C45 Mesothelioma
0.005 0.995 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.004 0.996 0.000
C45.7 Mesothelioma of other sites
0.004 0.996 0.000
S02.31 Fracture of orbital floor (open)
0.004 0.996 0.000
I73 Other peripheral vascular diseases
0.000 0.996 0.004
T79.4 Traumatic shock
0.000 0.996 0.004
Z43.6 Attention to other artificial openings of urinary tract
0.004 0.996 0.000
I73.0 Raynaud's syndrome
0.000 0.996 0.004
T79.9 Unspecified early complication of trauma
0.000 0.996 0.003
T79.2 Traumatic secondary and recurrent haemorrhage
0.000 0.996 0.003
T79.1 Fat embolism (traumatic)
0.000 0.996 0.003
T79.0 Air embolism (traumatic)
0.000 0.996 0.003
C45.2 Mesothelioma of pericardium
0.003 0.996 0.000
C45.1 Mesothelioma of peritoneum
0.003 0.996 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.003 0.997 0.000
T79.8 Other early complications of trauma
0.000 0.997 0.003
T79.7 Traumatic subcutaneous emphysema
0.000 0.997 0.003
I73.8 Other specified peripheral vascular diseases
0.000 0.997 0.003
S02.20 Fracture of nasal bones (closed)
0.003 0.997 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.003 0.997 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.003 0.997 0.000
S06 Intracranial injury
0.003 0.997 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.003 0.997 0.000
S06.4 Epidural haemorrhage
0.003 0.997 0.000
T79.5 Traumatic anuria
0.000 0.997 0.003
M07.3 Other psoriatic arthropathies
0.003 0.997 0.000
S06.5 Traumatic subdural haemorrhage
0.003 0.997 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.003 0.997 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.997 0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.003 0.997 0.000
S06.2 Diffuse brain injury
0.003 0.997 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.000 0.997 0.003
Q61.0 Congenital single renal cyst
0.000 0.997 0.003
M07.34 Other psoriatic arthropathies (Hand)
0.003 0.997 0.000
F43 Reaction to severe stress, and adjustment disorders
0.003 0.997 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.003 0.997 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.003 0.997 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.000 0.997 0.003
I35.9 Aortic valve disorder, unspecified
0.003 0.997 0.000
M07.38 Other psoriatic arthropathies (Other)
0.002 0.997 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.000 0.997 0.003
F43.2 Adjustment disorders
0.002 0.997 0.000
N83.2 Other and unspecified ovarian cysts
0.003 0.997 0.000
N85.4 Malposition of uterus
0.000 0.998 0.002
S06.7 Intracranial injury with prolonged coma
0.002 0.998 0.000
S06.3 Focal brain injury
0.002 0.998 0.000
S06.41 Epidural haemorrhage (with open intracranial wound)
0.002 0.998 0.000
G83.9 Paralytic syndrome, unspecified
0.000 0.998 0.002
X59.3 Sports and athletics area
0.000 0.998 0.002
M79.79 Fibromyalgia (Site unspecified)
0.002 0.998 0.000
H47.3 Other disorders of optic disk
0.000 0.998 0.002
M07.33 Other psoriatic arthropathies (Forearm)
0.002 0.998 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.002 0.998 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.002 0.998 0.000
F43.9 Reaction to severe stress, unspecified
0.002 0.998 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.000 0.998 0.002
M25.47 Effusion of joint (Ankle and foot)
0.000 0.998 0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.002 0.998 0.000
N36.9 Urethral disorder, unspecified
0.000 0.998 0.002
M40.26 Other and unspecified kyphosis (Lumbar region)
0.000 0.998 0.002
S06.21 Diffuse brain injury (with open intracranial wound)
0.002 0.998 0.000
S06.9 Intracranial injury, unspecified
0.002 0.998 0.000
S06.1 Traumatic cerebral oedema
0.002 0.998 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.002 0.998 0.000
S02.2 Fracture of nasal bones
0.002 0.998 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.002 0.998 0.000
F43.8 Other reactions to severe stress
0.002 0.998 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.002 0.998 0.000
G83.2 Monoplegia of upper limb
0.000 0.998 0.002
O26.2 Pregnancy care of habitual aborter
0.000 0.998 0.002
O26.0 Excessive weight gain in pregnancy
0.000 0.998 0.002
D03.5 Melanoma in situ of trunk
0.000 0.998 0.002
O73 Retained placenta and membranes, without haemorrhage
0.000 0.998 0.002
K55.0 Acute vascular disorders of intestine
0.002 0.998 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.002 0.998 0.000
S06.8 Other intracranial injuries
0.002 0.998 0.000
M40.24 Other and unspecified kyphosis (Thoracic region)
0.000 0.998 0.002
M40.2 Other and unspecified kyphosis
0.000 0.998 0.002
O26.4 Herpes gestationis
0.000 0.998 0.002
O26.1 Low weight gain in pregnancy
0.000 0.998 0.002
M85.6 Other cyst of bone
0.002 0.998 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.002 0.998 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.002 0.998 0.000
C84.5 Other and unspecified T-cell lymphomas
0.002 0.998 0.000
S06.31 Focal brain injury (with open intracranial wound)
0.002 0.998 0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.002 0.998 0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.002 0.998 0.000
G83.1 Monoplegia of lower limb
0.000 0.998 0.002
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.000 0.998 0.002
M85.67 Other cyst of bone (Ankle and foot)
0.002 0.998 0.000
O26.5 Maternal hypotension syndrome
0.000 0.998 0.002
S06.30 Focal brain injury (without open intracranial wound)
0.002 0.998 0.000
K62.7 Radiation proctitis
0.000 0.998 0.002
R73.9 Hyperglycaemia, unspecified
0.002 0.998 0.000
G83 Other paralytic syndromes
0.000 0.998 0.002
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.002 0.998 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.000 0.998 0.002
M40.29 Other and unspecified kyphosis (Site unspecified)
0.000 0.998 0.002
T79-T79 Certain early complications of trauma
0.000 0.998 0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.002 0.998 0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.002 0.998 0.000
Z50.1 Other physical therapy
0.002 0.998 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.002 0.998 0.000
K59.8 Other specified functional intestinal disorders
0.000 0.998 0.002
N36.0 Urethral fistula
0.000 0.998 0.002
S06.0 Concussion
0.002 0.998 0.000
S02 Fracture of skull and facial bones
0.002 0.998 0.000
N36.2 Urethral caruncle
0.000 0.998 0.002
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.000 0.998 0.002
M40.25 Other and unspecified kyphosis (Thoracolumbar region)
0.000 0.998 0.002
M48.02 Spinal stenosis (Cervical region)
0.000 0.998 0.002
M85.68 Other cyst of bone (Other)
0.002 0.998 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.002 0.998 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.998 0.002
N36 Other disorders of urethra
0.000 0.998 0.002
S06.81 Other intracranial injuries (with open intracranial wound)
0.002 0.998 0.000
D25.0 Submucous leiomyoma of uterus
0.002 0.998 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.002 0.998 0.000
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)
0.000 0.998 0.002
M40.27 Other and unspecified kyphosis (Lumbosacral region)
0.000 0.998 0.002
M40.23 Other and unspecified kyphosis (Cervicothoracic region)
0.000 0.998 0.002
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)
0.000 0.998 0.002
M40.20 Other and unspecified kyphosis (Multiple sites in spine)
0.000 0.998 0.002
M85.69 Other cyst of bone (Site unspecified)
0.002 0.998 0.000
M85.66 Other cyst of bone (Lower leg)
0.002 0.998 0.000
M85.63 Other cyst of bone (Forearm)
0.002 0.998 0.000
M85.62 Other cyst of bone (Upper arm)
0.002 0.998 0.000
M85.61 Other cyst of bone (Shoulder region)
0.002 0.998 0.000
M85.60 Other cyst of bone (Multiple sites)
0.002 0.998 0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.002 0.998 0.000
R06.2 Wheezing
0.000 0.998 0.002
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.002 0.998 0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.002 0.998 0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.002 0.998 0.000
H61.3 Acquired stenosis of external ear canal
0.000 0.998 0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.002 0.998 0.000
S02.7 Multiple fractures involving skull and facial bones
0.002 0.998 0.000
W10.8 Other specified place
0.002 0.998 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.998 0.002
F43.1 Posttraumatic stress disorder
0.002 0.998 0.000
M85.8 Other specified disorders of bone density and structure
0.002 0.998 0.000
M85.64 Other cyst of bone (Hand)
0.002 0.998 0.000
N36.8 Other specified disorders of urethra
0.000 0.998 0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.002 0.998 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.002 0.998 0.000
C46 Kaposi's sarcoma
0.002 0.998 0.000
G83.5 Locked-in syndrome
0.000 0.998 0.002
G83.3 Monoplegia, unspecified
0.000 0.998 0.002
G83.0 Diplegia of upper limbs
0.000 0.998 0.002
M85.4 Solitary bone cyst
0.002 0.998 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.002 0.998 0.000
M40.22 Other and unspecified kyphosis (Cervical region)
0.000 0.998 0.001
S02.21 Fracture of nasal bones (open)
0.001 0.998 0.000
S02.70 Multiple fractures involving skull and facial bones (closed)
0.002 0.998 0.000
C48.2 Peritoneum, unspecified
0.002 0.998 0.000
C48.0 Retroperitoneum
0.002 0.998 0.000
M85 Other disorders of bone density and structure
0.002 0.998 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.000 0.998 0.002
T93.8 Sequelae of other specified injuries of lower limb
0.000 0.998 0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.002 0.998 0.000
B35.1 Tinea unguium
0.000 0.998 0.002
C84.4 Peripheral T-cell lymphoma
0.002 0.998 0.000
N43.3 Hydrocele, unspecified
0.000 0.998 0.002
Q24.4 Congenital subaortic stenosis
0.002 0.998 0.000
S06.01 Concussion (with open intracranial wound)
0.001 0.998 0.000
I89.0 Lymphoedema, not elsewhere classified
0.002 0.998 0.000
E14.3 With ophthalmic complications
0.002 0.998 0.000
N36.1 Urethral diverticulum
0.000 0.998 0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.000 0.998 0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.002 0.998 0.000
G71.1 Myotonic disorders
0.002 0.998 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.000 0.998 0.002
Q61 Cystic kidney disease
0.000 0.998 0.002
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.001 0.998 0.000
C84.0 Mycosis fungoides
0.001 0.998 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.002 0.998 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.000 0.998 0.002
M25.44 Effusion of joint (Hand)
0.000 0.998 0.001
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.001 0.998 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.001 0.998 0.000
M85.0 Fibrous dysplasia (monostotic)
0.001 0.998 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.002 0.998 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.001 0.998 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.001 0.998 0.000
I77.1 Stricture of artery
0.000 0.998 0.002
M40.5 Lordosis, unspecified
0.000 0.998 0.001
Q24 Other congenital malformations of heart
0.002 0.998 0.000
M40.56 Lordosis, unspecified (Lumbar region)
0.000 0.998 0.001
M40.52 Lordosis, unspecified (Cervical region)
0.000 0.998 0.001
M66.06 Rupture of popliteal cyst-Lower leg
0.000 0.998 0.001
S06.80 Other intracranial injuries (without open intracranial wound)
0.001 0.998 0.000
Q61.3 Polycystic kidney, unspecified
0.000 0.998 0.002
Q28 Other congenital malformations of circulatory system
0.001 0.998 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.998 0.000
M85.49 Solitary bone cyst (Site unspecified)
0.001 0.998 0.000
M85.48 Solitary bone cyst (Other)
0.001 0.998 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.001 0.998 0.000
M85.44 Solitary bone cyst (Hand)
0.001 0.998 0.000
M85.43 Solitary bone cyst (Forearm)
0.001 0.998 0.000
M85.42 Solitary bone cyst (Upper arm)
0.001 0.998 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.001 0.998 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.001 0.998 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.001 0.998 0.000
C46.9 Kaposi's sarcoma, unspecified
0.001 0.998 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.001 0.998 0.000
C46.7 Kaposi's sarcoma of other sites
0.001 0.998 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.001 0.998 0.000
C46.2 Kaposi's sarcoma of palate
0.001 0.998 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.001 0.998 0.000
C46.0 Kaposi's sarcoma of skin
0.001 0.998 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.001 0.998 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.001 0.998 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.001 0.998 0.000
C47.5 Peripheral nerves of pelvis
0.001 0.998 0.000
C47.4 Peripheral nerves of abdomen
0.001 0.998 0.000
C47.3 Peripheral nerves of thorax
0.001 0.998 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.001 0.998 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.001 0.998 0.000
C47.0 Peripheral nerves of head, face and neck
0.001 0.998 0.000
G83.8 Other specified paralytic syndromes
0.000 0.998 0.001
M85.2 Hyperostosis of skull
0.001 0.998 0.000
O14.9 Preeclampsia, unspecified
0.000 0.998 0.001
Q28.0 Arteriovenous malformation of precerebral vessels
0.001 0.998 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.000 0.998 0.001
M85.5 Aneurysmal bone cyst
0.001 0.999 0.000
M85.3 Osteitis condensans
0.001 0.999 0.000
M85.1 Skeletal fluorosis
0.001 0.999 0.000
Q24.5 Malformation of coronary vessels
0.001 0.999 0.000
Q28.3 Other malformations of cerebral vessels
0.001 0.999 0.000
M85.46 Solitary bone cyst (Lower leg)
0.001 0.999 0.000
Q24.0 Dextrocardia
0.001 0.999 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.001 0.999 0.000
F12.1 Harmful use
0.000 0.999 0.001
G83.4 Cauda equina syndrome
0.000 0.999 0.001
M25.4 Effusion of joint
0.000 0.999 0.001
O62.3 Precipitate labour
0.001 0.999 0.000
Q61.2 Polycystic kidney, adult type
0.000 0.999 0.001
Y65.8 Other specified misadventures during surgical and medical care
0.000 0.999 0.001
C49 Malignant neoplasm of other connective and soft tissue
0.001 0.999 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.001 0.999 0.000
C49.3 Connective and soft tissue of thorax
0.001 0.999 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.999 0.001
N99.1 Postprocedural urethral stricture
0.001 0.999 0.000
M85.22 Hyperostosis of skull-Upper arm
0.001 0.999 0.000
C49.5 Connective and soft tissue of pelvis
0.001 0.999 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.001 0.999 0.000
N81.9 Female genital prolapse, unspecified
0.000 0.999 0.001
O62.1 Secondary uterine inertia
0.001 0.999 0.000
R23.8 Other and unspecified skin changes
0.000 0.999 0.001
S02.8 Fractures of other skull and facial bones
0.001 0.999 0.000
M40 Kyphosis and lordosis
0.000 0.999 0.001
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.001 0.999 0.000
K73.9 Chronic hepatitis, unspecified
0.001 0.999 0.000
Q61.9 Cystic kidney disease, unspecified
0.000 0.999 0.001
Q61.8 Other cystic kidney diseases
0.000 0.999 0.001
Q61.4 Renal dysplasia
0.000 0.999 0.001
Q61.1 Polycystic kidney, infantile type
0.000 0.999 0.001
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.001 0.999 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.001 0.999 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.001 0.999 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.001 0.999 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.001 0.999 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.001 0.999 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.001 0.999 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.001 0.999 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.001 0.999 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.001 0.999 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.001 0.999 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.001 0.999 0.000
C84.3 Lymphoepithelioid lymphoma
0.001 0.999 0.000
C84.2 T-zone lymphoma
0.001 0.999 0.000
C84.1 Sezary's diease
0.001 0.999 0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage
0.000 0.999 0.001
S02.5 Fracture of tooth
0.001 0.999 0.000
X59 Exposure to unspecified factor
0.000 0.999 0.001
M40.59 Lordosis, unspecified (Site unspecified)
0.000 0.999 0.001
M40.58 Lordosis, unspecified (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M40.57 Lordosis, unspecified (Lumbosacral region)
0.000 0.999 0.001
M40.55 Lordosis, unspecified (Thoracolumbar region)
0.000 0.999 0.001
M40.54 Lordosis, unspecified (Thoracic region)
0.000 0.999 0.001
M40.53 Lordosis, unspecified (Cervicothoracic region)
0.000 0.999 0.001
M40.51 Lordosis, unspecified (Occipito-atlanto-axial region)
0.000 0.999 0.001
M40.50 Lordosis, unspecified (Multiple sites in spine)
0.000 0.999 0.001
M85.9 Disorder of bone density and structure, unspecified
0.001 0.999 0.000
Q24.3 Pulmonary infundibular stenosis
0.001 0.999 0.000
Q24.2 Cor triatriatum
0.001 0.999 0.000
Q24.1 Levocardia
0.001 0.999 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.999 0.001
M85.29 Hyperostosis of skull-Site unspec
0.001 0.999 0.000
M85.28 Hyperostosis of skull-Other
0.001 0.999 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.001 0.999 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.001 0.999 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.001 0.999 0.000
M85.24 Hyperostosis of skull-Hand
0.001 0.999 0.000
M85.23 Hyperostosis of skull-Forearm
0.001 0.999 0.000
M85.21 Hyperostosis of skull-Shldr region
0.001 0.999 0.000
S36.00 Injury of spleen (without open wound into cavity)
0.001 0.999 0.000
B35.6 Tinea cruris
0.000 0.999 0.001
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.000 0.999 0.001
Q28.9 Congenital malformation of circulatory system, unspecified
0.001 0.999 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.001 0.999 0.000
Q28.1 Other malformations of precerebral vessels
0.001 0.999 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.999 0.001
M25.43 Effusion of joint (Forearm)
0.000 0.999 0.001
M25.41 Effusion of joint (Shoulder region)
0.000 0.999 0.001
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.999 0.001
M85.19 Skeletal fluorosis (Site unspecified)
0.001 0.999 0.000
M85.18 Skeletal fluorosis (Other)
0.001 0.999 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.001 0.999 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.001 0.999 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.001 0.999 0.000
M85.14 Skeletal fluorosis (Hand)
0.001 0.999 0.000
M85.13 Skeletal fluorosis (Forearm)
0.001 0.999 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.001 0.999 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.001 0.999 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.001 0.999 0.000
M85.39 Osteitis condensans (Site unspecified)
0.001 0.999 0.000
M85.38 Osteitis condensans (Other)
0.001 0.999 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.001 0.999 0.000
M85.36 Osteitis condensans (Lower leg)
0.001 0.999 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.001 0.999 0.000
M85.34 Osteitis condensans (Hand)
0.001 0.999 0.000
M85.33 Osteitis condensans (Forearm)
0.001 0.999 0.000
M85.32 Osteitis condensans (Upper arm)
0.001 0.999 0.000
M85.31 Osteitis condensans (Shoulder region)
0.001 0.999 0.000
M85.30 Osteitis condensans (Multiple sites)
0.001 0.999 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.001 0.999 0.000
M85.58 Aneurysmal bone cyst (Other)
0.001 0.999 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.001 0.999 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.001 0.999 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.001 0.999 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.001 0.999 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.001 0.999 0.000
M85.52 Aneurysmal bone cyst (Upper arm)
0.001 0.999 0.000
M85.51 Aneurysmal bone cyst (Shoulder region)
0.001 0.999 0.000
M85.50 Aneurysmal bone cyst (Multiple sites)
0.001 0.999 0.000
D61.9 Aplastic anaemia, unspecified
0.001 0.999 0.000
I86.8 Varicose veins of other specified sites
0.001 0.999 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.999 0.001
S02.0 Fracture of vault of skull
0.001 0.999 0.000
V27.4 Driver injured in traffic accident
0.001 0.999 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.000 0.999 0.001
M07 Psoriatic and enteropathic arthropathies
0.001 0.999 0.000
M25.49 Effusion of joint (Site unspecified)
0.000 0.999 0.001
M25.48 Effusion of joint (Other)
0.000 0.999 0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.001 0.999 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.001 0.999 0.000
F64.0 Transsexualism
0.000 0.999 0.001
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.999 0.001
H60.5 Acute otitis externa, non-infective
0.000 0.999 0.001
K74.6 Other and unspecified cirrhosis of liver
0.001 0.999 0.000
Z89.6 Acquired absence of leg above knee
0.001 0.999 0.000
C48.1 Specified parts of peritoneum
0.001 0.999 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.001 0.999 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.001 0.999 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.999 0.001
H60.4 Cholesteatoma of external ear
0.000 0.999 0.001
N36.3 Prolapsed urethral mucosa
0.000 0.999 0.001
M85.20 Hyperostosis of skull-Mult sites
0.001 0.999 0.000
S02.81 Fractures of other skull and facial bones (open)
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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