TreeWAS – Variant ID: rs13190655

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I78.1 Naevus, nonneoplastic	0.000	0.986	0.014
I78 Diseases of capillaries	0.000	0.990	0.010
I78.9 Disease of capillaries, unspecified	0.000	0.993	0.007
I78.8 Other diseases of capillaries	0.000	0.993	0.007
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.993	0.007
M24 Other specific joint derangements	0.007	0.993	0.000
M24.1 Other articular cartilage disorders	0.007	0.993	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.007	0.993	0.000
M24.2 Disorder of ligament	0.007	0.993	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.993	0.007
I74 Arterial embolism and thrombosis	0.000	0.993	0.007
M81.99 Osteoporosis, unspecified (Site unspecified)	0.007	0.993	0.000
M81.9 Osteoporosis, unspecified	0.007	0.993	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.994	0.006
M24.4 Recurrent dislocation and subluxation of joint	0.006	0.994	0.000
M24.23 Disorder of ligament (Forearm)	0.006	0.994	0.000
M81.98 Osteoporosis, unspecified (Other)	0.006	0.994	0.000
M24.0 Loose body in joint	0.006	0.994	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.006	0.994	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.994	0.006
M31.6 Other giant cell arteritis	0.006	0.994	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.006	0.994	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.006	0.994	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.006	0.994	0.000
M24.24 Disorder of ligament (Hand)	0.005	0.994	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.006	0.994	0.000
M24.5 Contracture of joint	0.005	0.995	0.000
M24.07 Loose body in joint (Ankle and foot)	0.005	0.995	0.000
I77 Other disorders of arteries and arterioles	0.000	0.995	0.005
M24.9 Joint derangement, unspecified	0.005	0.995	0.000
M24.7 Protrusio acetabuli	0.005	0.995	0.000
M24.6 Ankylosis of joint	0.005	0.995	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.005	0.995	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.995	0.005
M24.19 Other articular cartilage disorders (Site unspecified)	0.005	0.995	0.000
M24.18 Other articular cartilage disorders (Other)	0.005	0.995	0.000
M24.14 Other articular cartilage disorders (Hand)	0.005	0.995	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.005	0.995	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.005	0.995	0.000
I71 Aortic aneurysm and dissection	0.000	0.995	0.005
M24.29 Disorder of ligament (Site unspecified)	0.005	0.995	0.000
M24.28 Disorder of ligament (Other)	0.005	0.995	0.000
M24.26 Disorder of ligament (Lower leg)	0.005	0.995	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.005	0.995	0.000
M24.22 Disorder of ligament (Upper arm)	0.005	0.995	0.000
M24.21 Disorder of ligament (Shoulder region)	0.005	0.995	0.000
M24.20 Disorder of ligament (Multiple sites)	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.995	0.005
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.995	0.005
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.995	0.005
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.995	0.005
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.005	0.995	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.005	0.995	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.995	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.005	0.995	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.995	0.005
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.005	0.995	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.005	0.995	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.005	0.995	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.005	0.995	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.005	0.995	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.005	0.995	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.005	0.995	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.005	0.995	0.000
I70 Atherosclerosis	0.000	0.995	0.005
I77.1 Stricture of artery	0.000	0.995	0.005
M31 Other necrotising vasculopathies	0.005	0.995	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.005	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M24.09 Loose body in joint (Site unspecified)	0.004	0.995	0.000
M24.08 Loose body in joint (Other)	0.004	0.995	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.995	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.995	0.000
M24.04 Loose body in joint (Hand)	0.004	0.995	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.995	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.004	0.995	0.000
M24.00 Loose body in joint (Multiple sites)	0.004	0.995	0.000
I72 Other aneurysm	0.000	0.995	0.005
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.004	0.995	0.000
I77.6 Arteritis, unspecified	0.000	0.995	0.004
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.996	0.004
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
M31.3 Wegener's granulomatosis	0.004	0.996	0.000
M24.54 Contracture of joint (Hand)	0.004	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.004	0.996	0.000
M24.58 Contracture of joint (Other)	0.004	0.996	0.000
M24.57 Contracture of joint (Ankle and foot)	0.004	0.996	0.000
M24.56 Contracture of joint (Lower leg)	0.004	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.53 Contracture of joint (Forearm)	0.004	0.996	0.000
M24.52 Contracture of joint (Upper arm)	0.004	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.004	0.996	0.000
M24.50 Contracture of joint (Multiple sites)	0.004	0.996	0.000
I77.5 Necrosis of artery	0.000	0.996	0.004
I77.4 Coeliac artery compression syndrome	0.000	0.996	0.004
I77.3 Arterial fibromuscular dysplasia	0.000	0.996	0.004
I77.2 Rupture of artery	0.000	0.996	0.004
I77.0 Arteriovenous fistula, acquired	0.000	0.996	0.004
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.004	0.996	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.004	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.004	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.004	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.004	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.004	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.004	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.004	0.996	0.000
M24.79 Protrusio acetabuli-Site unspec	0.004	0.996	0.000
M24.78 Protrusio acetabuli-Other	0.004	0.996	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.004	0.996	0.000
M24.76 Protrusio acetabuli-Lower leg	0.004	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.004	0.996	0.000
M24.74 Protrusio acetabuli-Hand	0.004	0.996	0.000
M24.73 Protrusio acetabuli-Forearm	0.004	0.996	0.000
M24.72 Protrusio acetabuli-Upper arm	0.004	0.996	0.000
M24.71 Protrusio acetabuli-Shldr region	0.004	0.996	0.000
M24.70 Protrusio acetabuli-Mult sites	0.004	0.996	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.004	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.004	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.004	0.996	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.004	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M24.94 Joint derangement, unspecified (Hand)	0.004	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.004	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.004	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.004	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.004	0.996	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
I72.4 Aneurysm of artery of lower extremity	0.000	0.996	0.004
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.996	0.004
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.996	0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.996	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.996	0.004
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.996	0.004
M81.49 Drug-induced osteoporosis (Site unspecified)	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.004	0.996	0.000
I71.0 Dissection of aorta [any part]	0.000	0.996	0.004
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
M84 Disorders of continuity of bone	0.004	0.996	0.000
I70.0 Atherosclerosis of aorta	0.000	0.996	0.004
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.996	0.004
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.996	0.004
I79.1 Aortitis in diseases classified elsewhere	0.000	0.996	0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.996	0.004
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.996	0.004
I70.9 Generalised and unspecified atherosclerosis	0.000	0.996	0.004
I70.8 Atherosclerosis of other arteries	0.000	0.996	0.004
I70.1 Atherosclerosis of renal artery	0.000	0.996	0.004
M31.9 Necrotising vasculopathy, unspecified	0.004	0.996	0.000
M31.8 Other specified necrotising vasculopathies	0.004	0.996	0.000
M31.7 Microscopic polyangiitis	0.004	0.996	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.004	0.996	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.004	0.996	0.000
M31.2 Lethal midline granuloma	0.004	0.996	0.000
M31.1 Thrombotic microangiopathy	0.004	0.996	0.000
M31.0 Hypersensitivity angiitis	0.004	0.996	0.000
M34 Systemic sclerosis	0.004	0.996	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.996	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.004	0.996	0.000
I72.9 Aneurysm of unspecified site	0.000	0.996	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.996	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.996	0.003
I72.2 Aneurysm of renal artery	0.000	0.996	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.996	0.003
S42.40 Fracture of lower end of humerus (closed)	0.004	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
M20-M25 Other joint disorders	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.997	0.003
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
I72.0 Aneurysm of carotid artery	0.000	0.997	0.003
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
M84.3 Stress fracture, not elsewhere classified	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.997	0.003
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.997	0.003
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.997	0.003
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.997	0.003
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.997	0.003
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.003	0.997	0.000
M34.0 Progressive systemic sclerosis	0.003	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.997	0.000
C34 Malignant neoplasm of bronchus and lung	0.003	0.997	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.003	0.997	0.000
M33 Dermatopolymyositis	0.003	0.997	0.000
M32 Systemic lupus erythematosus	0.003	0.997	0.000
M30 Polyarteritis nodosa and related conditions	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
C34.8 Overlapping lesion of bronchus and lung	0.003	0.997	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
Z50.8 Care involving use of rehabilitation procedures	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.997	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.997	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.997	0.000
T40.4 Other synthetic narcotics	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
M21 Other acquired deformities of limbs	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.002	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.997	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.997	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.997	0.000
N40 Hyperplasia of prostate	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.002	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.002	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.002	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.002	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.002	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M22.2 Patellofemoral disorders	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
Z50.1 Other physical therapy	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.002	0.998	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.002	0.998	0.000
M30.2 Juvenile polyarteritis	0.002	0.998	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.002	0.998	0.000
M30.0 Polyarteritis nodosa	0.002	0.998	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.002	0.998	0.000
M32.8 Other forms of systemic lupus erythematosus	0.002	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.002	0.998	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.002	0.998	0.000
M33.9 Dermatopolymyositis, unspecified	0.002	0.998	0.000
M33.2 Polymyositis	0.002	0.998	0.000
M33.1 Other dermatomyositis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations