TreeWAS – Variant ID: rs13273088

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E23.0 Hypopituitarism	0.080	0.920	0.000
E23 Hypofunction and other disorders of pituitary gland	0.080	0.920	0.000
E23.2 Diabetes insipidus	0.075	0.924	0.000
E20-E35 Disorders of other endocrine glands	0.066	0.934	0.000
E34 Other endocrine disorders	0.065	0.935	0.000
E24 Cushing's syndrome	0.062	0.938	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.062	0.938	0.000
E23.6 Other disorders of pituitary gland	0.062	0.938	0.000
E23.7 Disorder of pituitary gland, unspecified	0.059	0.941	0.000
E34.8 Other specified endocrine disorders	0.058	0.942	0.000
E34.0 Carcinoid syndrome	0.057	0.943	0.000
E23.1 Drug-induced hypopituitarism	0.057	0.943	0.000
E24.9 Cushing's syndrome, unspecified	0.056	0.944	0.000
E26 Hyperaldosteronism	0.053	0.947	0.000
E34.9 Endocrine disorder, unspecified	0.052	0.948	0.000
E24.2 Drug-induced Cushing's syndrome	0.051	0.948	0.000
E31 Polyglandular dysfunction	0.051	0.949	0.000
E34.3 Short stature, not elsewhere classified	0.051	0.949	0.000
E24.8 Other Cushing's syndrome	0.049	0.951	0.000
E25 Adrenogenital disorders	0.048	0.952	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.047	0.952	0.000
E30 Disorders of puberty, not elsewhere classified	0.047	0.952	0.000
E34.5 Androgen resistance syndrome	0.047	0.953	0.000
E34.4 Constitutional tall stature	0.047	0.953	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.047	0.953	0.000
E34.1 Other hypersecretion of intestinal hormones	0.047	0.953	0.000
E32 Diseases of thymus	0.045	0.955	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.045	0.955	0.000
E24.3 Ectopic ACTH syndrome	0.045	0.955	0.000
E24.1 Nelson's syndrome	0.045	0.955	0.000
E26.0 Primary hyperaldosteronism	0.044	0.956	0.000
E24.0 Pituitary-dependent Cushing's disease	0.044	0.956	0.000
E28 Ovarian dysfunction	0.042	0.958	0.000
E27 Other disorders of adrenal gland	0.042	0.958	0.000
E22 Hyperfunction of pituitary gland	0.041	0.959	0.000
E20 Hypoparathyroidism	0.041	0.959	0.000
E31.0 Autoimmune polyglandular failure	0.040	0.960	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.961	0.039
J38.7 Other diseases of larynx	0.000	0.961	0.039
E26.9 Hyperaldosteronism, unspecified	0.039	0.961	0.000
E26.8 Other hyperaldosteronism	0.038	0.962	0.000
E26.1 Secondary hyperaldosteronism	0.038	0.962	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.963	0.037
E31.9 Polyglandular dysfunction, unspecified	0.037	0.963	0.000
E31.8 Other polyglandular dysfunction	0.037	0.963	0.000
E31.1 Polyglandular hyperfunction	0.037	0.963	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.037	0.963	0.000
E29 Testicular dysfunction	0.036	0.964	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.035	0.965	0.000
E22.0 Acromegaly and pituitary gigantism	0.035	0.965	0.000
E25.9 Adrenogenital disorder, unspecified	0.034	0.965	0.000
E25.8 Other adrenogenital disorders	0.034	0.965	0.000
E30.9 Disorder of puberty, unspecified	0.034	0.966	0.000
E30.8 Other disorders of puberty	0.034	0.966	0.000
E30.1 Precocious puberty	0.034	0.966	0.000
E30.0 Delayed puberty	0.034	0.966	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.034	0.966	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.034	0.966	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.034	0.966	0.000
J38.4 Oedema of larynx	0.000	0.967	0.033
E32.8 Other diseases of thymus	0.032	0.967	0.000
E32.1 Abscess of thymus	0.032	0.967	0.000
E32.0 Persistent hyperplasia of thymus	0.032	0.967	0.000
E27.1 Primary adrenocortical insufficiency	0.031	0.969	0.000
E27.9 Disorder of adrenal gland, unspecified	0.031	0.969	0.000
J38.6 Stenosis of larynx	0.000	0.969	0.031
E28.9 Ovarian dysfunction, unspecified	0.030	0.969	0.000
E28.8 Other ovarian dysfunction	0.030	0.969	0.000
E28.1 Androgen excess	0.030	0.969	0.000
E28.0 Oestrogen excess	0.030	0.969	0.000
E27.8 Other specified disorders of adrenal gland	0.030	0.970	0.000
E28.3 Primary ovarian failure	0.030	0.970	0.000
E27.5 Adrenomedullary hyperfunction	0.030	0.970	0.000
E27.0 Other adrenocortical overactivity	0.030	0.970	0.000
E32.9 Disease of thymus, unspecified	0.030	0.970	0.000
E20.1 Pseudohypoparathyroidism	0.030	0.970	0.000
E22.8 Other hyperfunction of pituitary gland	0.030	0.970	0.000
E20.0 Idiopathic hypoparathyroidism	0.030	0.970	0.000
E22.1 Hyperprolactinaemia	0.030	0.970	0.000
E21.0 Primary hyperparathyroidism	0.030	0.970	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.029	0.971	0.000
J38.5 Laryngeal spasm	0.000	0.971	0.029
E20.8 Other hypoparathyroidism	0.029	0.971	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.028	0.971	0.000
E27.2 Addisonian crisis	0.027	0.972	0.000
E21.4 Other specified disorders of parathyroid gland	0.027	0.973	0.000
E29.9 Testicular dysfunction, unspecified	0.027	0.973	0.000
E21.2 Other hyperparathyroidism	0.027	0.973	0.000
E29.8 Other testicular dysfunction	0.026	0.974	0.000
E29.0 Testicular hyperfunction	0.026	0.974	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.026	0.974	0.000
J38.3 Other diseases of vocal cords	0.000	0.974	0.026
E28.2 Polycystic ovarian syndrome	0.025	0.975	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.025	0.975	0.000
E20.9 Hypoparathyroidism, unspecified	0.025	0.975	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.025	0.975	0.000
J38.2 Nodules of vocal cords	0.000	0.976	0.023
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.978	0.022
J38.0 Paralysis of vocal cords and larynx	0.000	0.983	0.017
K26.3 Acute without haemorrhage or perforation	0.016	0.984	0.000
E29.1 Testicular hypofunction	0.012	0.987	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.012	0.987	0.001
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.011	0.989	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.989	0.000
Y83.6 Removal of other organ (partial) (total)	0.009	0.991	0.000
K25.7 Chronic without haemorrhage or perforation	0.007	0.993	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.006	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.994	0.006
K86.1 Other chronic pancreatitis	0.006	0.994	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.005	0.995	0.000
K86.8 Other specified diseases of pancreas	0.005	0.995	0.000
C71.2 Temporal lobe	0.000	0.995	0.005
K86.3 Pseudocyst of pancreas	0.005	0.995	0.000
K86 Other diseases of pancreas	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.000	0.995	0.005
Z88.6 Personal history of allergy to analgesic agent	0.005	0.995	0.000
C71.8 Overlapping lesion of brain	0.000	0.995	0.005
C71.1 Frontal lobe	0.000	0.996	0.004
Z51.3 Blood transfusion without reported diagnosis	0.004	0.996	0.000
C71.9 Brain, unspecified	0.000	0.996	0.004
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.000	0.996	0.004
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.004
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
D35.0 Adrenal gland	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
C71.7 Brain stem	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
C71.6 Cerebellum	0.000	0.997	0.003
C71.4 Occipital lobe	0.000	0.997	0.003
R29.1 Meningismus	0.000	0.997	0.003
O32.0 Maternal care for unstable lie	0.000	0.997	0.003
K86.2 Cyst of pancreas	0.003	0.997	0.000
R29.4 Clicking hip	0.000	0.997	0.003
R29.3 Abnormal posture	0.000	0.997	0.003
R29.0 Tetany	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
K86.9 Disease of pancreas, unspecified	0.003	0.997	0.000
R29.2 Abnormal reflex	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.997	0.003
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
D35.2 Pituitary gland	0.003	0.997	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
K81.1 Chronic cholecystitis	0.002	0.998	0.000
K25.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
D35.9 Endocrine gland, unspecified	0.002	0.998	0.000
D35.8 Pluriglandular involvement	0.002	0.998	0.000
D35.7 Other specified endocrine glands	0.002	0.998	0.000
D35.6 Aortic body and other paraganglia	0.002	0.998	0.000
D35.5 Carotid body	0.002	0.998	0.000
D35.4 Pineal gland	0.002	0.998	0.000
D35.3 Craniopharyngeal duct	0.002	0.998	0.000
D35.1 Parathyroid gland	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
K25 Gastric ulcer	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
K25.0 Acute with haemorrhage	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.998	0.002
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.998	0.002
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.001
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
K25.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
Y83.4 Other reconstructive surgery	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.001	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
K25.1 Acute with perforation	0.001	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.001	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.001	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.998	0.000
S62.50 Fracture of thumb (closed)	0.001	0.998	0.000
C67.5 Bladder neck	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
F20 Schizophrenia	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.001	0.998	0.000
A87.9 Viral meningitis, unspecified	0.001	0.998	0.000
M41.4 Neuromuscular scoliosis	0.001	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.998	0.000
D69.1 Qualitative platelet defects	0.001	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.001
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.999	0.000
C67.4 Posterior wall of bladder	0.000	0.999	0.001
D69.4 Other primary thrombocytopenia	0.001	0.999	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
V18.3 Person injured while boarding or alighting	0.000	0.999	0.001
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.999	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.999	0.001
Q43.0 Meckel's diverticulum	0.000	0.999	0.001
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.999	0.001
I60.8 Other subarachnoid haemorrhage	0.000	0.999	0.001
M41.3 Thoracogenic scoliosis	0.001	0.999	0.000
M41.2 Other idiopathic scoliosis	0.001	0.999	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.999	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.999	0.000
S90.0 Contusion of ankle	0.001	0.999	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.999	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.999	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.999	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.999	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.999	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
F20.5 Residual schizophrenia	0.001	0.999	0.000
F23 Acute and transient psychotic disorders	0.001	0.999	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.001	0.999	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.999	0.000
N41.1 Chronic prostatitis	0.000	0.999	0.001
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.999	0.001
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.999	0.001
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.999	0.000
C67.3 Anterior wall of bladder	0.000	0.999	0.001
K51.8 Other ulcerative colitis	0.001	0.999	0.000
M50.9 Cervical disk disorder, unspecified	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
R23.1 Pallor	0.001	0.999	0.000
V18.5 Passenger injured in traffic accident	0.000	0.999	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.999	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.999	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.999	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M71.38 Other bursal cyst (Other)	0.000	0.999	0.001
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.999	0.000
K91.3 Postoperative intestinal obstruction	0.001	0.999	0.000
O42 Premature rupture of membranes	0.000	0.999	0.001
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.999	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
I20.8 Other forms of angina pectoris	0.000	0.999	0.001
I67.1 Cerebral aneurysm, nonruptured	0.000	0.999	0.001
E16 Other disorders of pancreatic internal secretion	0.001	0.999	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.999	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.999	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.999	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.999	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.999	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.999	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.999	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.999	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.999	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.999	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
C44.3 Skin of other and unspecified parts of face	0.000	0.999	0.001
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
F29 Unspecified nonorganic psychosis	0.001	0.999	0.000
M50 Cervical disk disorders	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
D69.0 Allergic purpura	0.001	0.999	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.999	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
M65.4 Radial styloid tenosynovitis [de Quervain]	0.001	0.999	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
V18.1 Passenger injured in nontraffic accident	0.000	0.999	0.001
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
E16.2 Hypoglycaemia, unspecified	0.001	0.999	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.999	0.000
M86.6 Other chronic osteomyelitis	0.001	0.999	0.000
N89.6 Tight hymenal ring	0.000	0.999	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.999	0.001
V18.4 Driver injured in traffic accident	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
F20.8 Other schizophrenia	0.001	0.999	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.999	0.000
I49.8 Other specified cardiac arrhythmias	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.999	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
C67 Malignant neoplasm of bladder	0.000	0.999	0.001
D59 Acquired haemolytic anaemia	0.001	0.999	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.999	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.999	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.999	0.000
E16.3 Increased secretion of glucagon	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.999	0.001
A46 Erysipelas	0.001	0.999	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.999	0.001
G93.3 Postviral fatigue syndrome	0.000	0.999	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.999	0.001
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.999	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.999	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.999	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.999	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.999	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.999	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.999	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.999	0.000
M86.68 Other chronic osteomyelitis (Other)	0.001	0.999	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.999	0.001
M34.8 Other forms of systemic sclerosis	0.001	0.999	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Y83.5 Amputation of limb(s)	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.000	0.999	0.001
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.999	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.999	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.999	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.999	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.999	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.999	0.001
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.999	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
R86.8 Other abnormal findings	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.000	0.999	0.001
C67.7 Urachus	0.000	0.999	0.001
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
H61.2 Impacted cerumen	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.000	0.999	0.001
S62 Fracture at wrist and hand level	0.000	0.999	0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.999	0.000
C67.6 Ureteric orifice	0.000	0.999	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.999	0.001
M50.8 Other cervical disk disorders	0.001	0.999	0.000
N64.9 Disorder of breast, unspecified	0.000	0.999	0.001
Q43.1 Hirschsprung's disease	0.000	0.999	0.001
Z49 Care involving dialysis	0.000	0.999	0.001
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.001	0.999	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.001	0.999	0.000
B17.1 Acute hepatitis C	0.000	0.999	0.001
D41.0 Kidney	0.000	0.999	0.001
E85.9 Amyloidosis, unspecified	0.000	0.999	0.001
H31.8 Other specified disorders of choroid	0.001	0.999	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.999	0.001
M34.1 CR(E)ST syndrome	0.001	0.999	0.000
W60.0 Home	0.000	0.999	0.001
C70 Malignant neoplasm of meninges	0.000	0.999	0.001
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.999	0.000
F42.2 Mixed obsessional thoughts and acts	0.001	0.999	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.001	0.999	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.999	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.999	0.001
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.999	0.001
L43.8 Other lichen planus	0.001	0.999	0.000
M50.0 Cervical disk disorder with myelopathy	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
M86.9 Osteomyelitis, unspecified	0.001	0.999	0.000
S62.5 Fracture of thumb	0.001	0.999	0.001
Z22.3 Carrier of other specified bacterial diseases	0.001	0.999	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.001	0.999	0.000
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
C70.9 Meninges, unspecified	0.000	0.999	0.001
C70.1 Spinal meninges	0.000	0.999	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.999	0.001
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.000	0.999	0.001
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
Q43.3 Congenital malformations of intestinal fixation	0.000	0.999	0.001
S62.4 Multiple fractures of metacarpal bones	0.000	0.999	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations