TreeWAS – Variant ID: rs1330225

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T50.9 Other and unspecified drugs, medicaments and biological substances	0.021	0.979	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.020	0.980	0.000
H10.9 Conjunctivitis, unspecified	0.020	0.980	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.019	0.981	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.981	0.019
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.018	0.982	0.000
T42.1 Iminostilbenes	0.017	0.983	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.017	0.983	0.000
T50.8 Diagnostic agents	0.017	0.983	0.000
S82.3 Fracture of lower end of tibia	0.000	0.983	0.017
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.983	0.017
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.016	0.983	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.016	0.984	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.016	0.984	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.016	0.984	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.984	0.016
T50.6 Antidotes and chelating agents, not elsewhere classified	0.016	0.984	0.000
T36 Poisoning by systemic antibiotics	0.015	0.985	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.015	0.985	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.985	0.015
S82 Fracture of lower leg, including ankle	0.000	0.985	0.015
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T50.7 Analeptics and opioid receptor antagonists	0.015	0.985	0.000
T50.5 Appetite depressants	0.015	0.985	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.015	0.985	0.000
T50.1 Loop [high-ceiling] diuretics	0.015	0.985	0.000
T50.0 Mineralocorticoids and their antagonists	0.015	0.985	0.000
T43.2 Other and unspecified antidepressants	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.985	0.000
T50.4 Drugs affecting uric acid metabolism	0.015	0.985	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.014	0.986	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.014	0.986	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.014	0.986	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.014	0.986	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.986	0.014
S82.2 Fracture of shaft of tibia	0.000	0.986	0.014
T43.3 Phenothiazine antipsychotics and neuroleptics	0.013	0.987	0.000
T38.0 Glucocorticoids and synthetic analogues	0.013	0.987	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.987	0.013
S82.31 Fracture of lower end of tibia (open)	0.000	0.987	0.013
T46 Poisoning by agents primarily affecting the cardiovascular system	0.013	0.987	0.000
T36.0 Penicillins	0.013	0.987	0.000
H10 Conjunctivitis	0.013	0.987	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.013	0.987	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.987	0.013
T48.6 Antiasthmatics, not elsewhere classified	0.012	0.987	0.000
T38.1 Thyroid hormones and substitutes	0.012	0.987	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.012	0.988	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.988	0.000
S82.5 Fracture of medial malleolus	0.000	0.988	0.012
T47.0 Histamine H(2)-receptor antagonists	0.012	0.988	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.012	0.988	0.000
T38.9 Other and unspecified hormone antagonists	0.012	0.988	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.012	0.988	0.000
T38.7 Androgens and anabolic congeners	0.012	0.988	0.000
T38.5 Other oestrogens and progestogens	0.012	0.988	0.000
T38.4 Oral contraceptives	0.012	0.988	0.000
T38.2 Antithyroid drugs	0.012	0.988	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
S82.86 Maisonneuve's fracture	0.000	0.988	0.012
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.011	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.989	0.000
T36.6 Rifamycins	0.011	0.989	0.000
T36.5 Aminoglycosides	0.011	0.989	0.000
T36.4 Tetracyclines	0.011	0.989	0.000
T36.3 Macrolides	0.011	0.989	0.000
T36.2 Chloramphenicol group	0.011	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.011	0.989	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.011	0.989	0.000
H10.3 Acute conjunctivitis, unspecified	0.011	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.989	0.000
T48.5 Anti-common-cold drugs	0.011	0.989	0.000
T48.4 Expectorants	0.011	0.989	0.000
T48.3 Antitussives	0.011	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
T48.0 Oxytocic drugs	0.011	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
S82.9 Fracture of lower leg, part unspecified	0.000	0.989	0.011
H18.8 Other specified disorders of cornea	0.000	0.989	0.011
S82.6 Fracture of lateral malleolus	0.000	0.989	0.011
T42.4 Benzodiazepines	0.011	0.989	0.000
T47.4 Other laxatives	0.011	0.989	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.989	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.989	0.000
T47.7 Emetics	0.010	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.010	0.989	0.000
T47.5 Digestants	0.010	0.989	0.000
T47.3 Saline and osmotic laxatives	0.010	0.989	0.000
T47.2 Stimulant laxatives	0.010	0.989	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.989	0.000
S81 Open wound of lower leg	0.000	0.989	0.011
T41.5 Therapeutic gases	0.010	0.990	0.000
T41.4 Anaesthetic, unspecified	0.010	0.990	0.000
T41.3 Local anaesthetics	0.010	0.990	0.000
T41.2 Other and unspecified general anaesthetics	0.010	0.990	0.000
T41.1 Intravenous anaesthetics	0.010	0.990	0.000
T41.0 Inhaled anaesthetics	0.010	0.990	0.000
T49.9 Topical agent, unspecified	0.010	0.990	0.000
T49.8 Other topical agents	0.010	0.990	0.000
T49.7 Dental drugs, topically applied	0.010	0.990	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.010	0.990	0.000
T49.5 Ophthalmological drugs and preparations	0.010	0.990	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.010	0.990	0.000
T49.3 Emollients, demulcents and protectants	0.010	0.990	0.000
T49.2 Local astringents and local detergents	0.010	0.990	0.000
T49.1 Antipruritics	0.010	0.990	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.990	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.990	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.990	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.990	0.010
T40.5 Cocaine	0.010	0.990	0.000
H10.0 Mucopurulent conjunctivitis	0.010	0.990	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.990	0.010
S82.51 Fracture of medial malleolus (open)	0.000	0.990	0.010
T46.1 Calcium-channel blockers	0.010	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.009	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.009	0.990	0.000
T46.7 Peripheral vasodilators	0.009	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.009	0.990	0.000
T40.1 Heroin	0.009	0.990	0.000
H10.8 Other conjunctivitis	0.009	0.990	0.000
H10.5 Blepharoconjunctivitis	0.009	0.990	0.000
H10.2 Other acute conjunctivitis	0.009	0.990	0.000
H10.1 Acute atopic conjunctivitis	0.009	0.990	0.000
S81.0 Open wound of knee	0.000	0.990	0.009
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
H10.4 Chronic conjunctivitis	0.009	0.991	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.991	0.009
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.009	0.991	0.000
S82.7 Multiple fractures of lower leg	0.000	0.991	0.009
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.009	0.991	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.009	0.991	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.009	0.991	0.000
T44.0 Anticholinesterase agents	0.009	0.991	0.000
T45.0 Antiallergic and antiemetic drugs	0.009	0.991	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.991	0.009
S82.21 Fracture of shaft of tibia (open)	0.000	0.991	0.009
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.009	0.991	0.000
T40.8 Lysergide [LSD]	0.009	0.991	0.000
T40.7 Cannabis (derivatives)	0.009	0.991	0.000
T40.3 Methadone	0.009	0.991	0.000
T40.0 Opium	0.009	0.991	0.000
S82.0 Fracture of patella	0.000	0.991	0.009
T46.3 Coronary vasodilators, not elsewhere classified	0.009	0.991	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.991	0.009
T45.9 Primarily systemic and haematological agent, unspecified	0.008	0.991	0.000
T45.8 Other primarily systemic and haematological agents	0.008	0.991	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.008	0.991	0.000
T45.6 Fibrinolysis-affecting drugs	0.008	0.991	0.000
T45.4 Iron and its compounds	0.008	0.991	0.000
T45.3 Enzymes, not elsewhere classified	0.008	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.992	0.008
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.992	0.008
S82.60 Fracture of lateral malleolus (closed)	0.000	0.992	0.008
S82.4 Fracture of fibula alone	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.992	0.008
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.992	0.008
T45.5 Anticoagulants	0.008	0.992	0.000
S82.1 Fracture of upper end of tibia	0.000	0.992	0.008
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.992	0.008
T45.2 Vitamins, not elsewhere classified	0.007	0.992	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.992	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.992	0.007
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.992	0.007
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.993	0.007
S88 Traumatic amputation of lower leg	0.000	0.993	0.007
S85 Injury of blood vessels at lower leg level	0.000	0.993	0.007
S84 Injury of nerves at lower leg level	0.000	0.993	0.007
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.993	0.007
T45.1 Antineoplastic and immunosuppressive drugs	0.007	0.993	0.000
S82.01 Fracture of patella (open)	0.000	0.993	0.007
S89 Other and unspecified injuries of lower leg	0.000	0.993	0.007
S81.7 Multiple open wounds of lower leg	0.000	0.993	0.007
S82.71 Multiple fractures of lower leg (open)	0.000	0.993	0.007
S86 Injury of muscle and tendon at lower leg level	0.000	0.993	0.007
T43.0 Tricyclic and tetracyclic antidepressants	0.007	0.993	0.000
S87 Crushing injury of lower leg	0.000	0.993	0.006
H90.2 Conductive hearing loss, unspecified	0.000	0.994	0.006
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.994	0.006
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.994	0.006
S83.3 Tear of articular cartilage of knee, current	0.000	0.994	0.006
S83.7 Injury to multiple structures of knee	0.000	0.994	0.006
S82.11 Fracture of upper end of tibia (open)	0.000	0.994	0.006
I22.1 Subsequent myocardial infarction of inferior wall	0.006	0.994	0.000
H18 Other disorders of cornea	0.000	0.994	0.006
M31.6 Other giant cell arteritis	0.000	0.994	0.006
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.994	0.006
S82.41 Fracture of fibula alone (open)	0.000	0.994	0.006
F25.1 Schizoaffective disorder, depressive type	0.006	0.994	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.006	0.994	0.000
S83.1 Dislocation of knee	0.000	0.994	0.006
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.994	0.006
F25 Schizoaffective disorders	0.006	0.994	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.994	0.006
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.994	0.006
L27 Dermatitis due to substances taken internally	0.000	0.994	0.006
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.994	0.005
S84.8 Injury of other nerves at lower leg level	0.000	0.994	0.005
S84.7 Injury of multiple nerves at lower leg level	0.000	0.994	0.005
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.994	0.005
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.994	0.005
S84.0 Injury of tibial nerve at lower leg level	0.000	0.994	0.005
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.994	0.005
S85.8 Injury of other blood vessels at lower leg level	0.000	0.994	0.005
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.994	0.005
S85.5 Injury of popliteal vein	0.000	0.994	0.005
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.994	0.005
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.994	0.005
S85.2 Injury of peroneal artery	0.000	0.994	0.005
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.994	0.005
S85.0 Injury of popliteal artery	0.000	0.994	0.005
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.994	0.005
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.994	0.005
S88.0 Traumatic amputation at knee level	0.000	0.994	0.005
H18.5 Hereditary corneal dystrophies	0.000	0.994	0.005
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.995	0.005
H90 Conductive and sensorineural hearing loss	0.000	0.995	0.005
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.995	0.005
D10.1 Tongue	0.000	0.995	0.005
S89.9 Unspecified injury of lower leg	0.000	0.995	0.005
H18.9 Disorder of cornea, unspecified	0.000	0.995	0.005
F25.9 Schizoaffective disorder, unspecified	0.005	0.995	0.000
S89.7 Multiple injuries of lower leg	0.000	0.995	0.005
S89.1 Other specified injuries of lower leg	0.000	0.995	0.005
S89.0 Multiple injuries of lower leg	0.000	0.995	0.005
S80.9 Superficial injury of lower leg, unspecified	0.000	0.995	0.005
S83.0 Dislocation of patella	0.000	0.995	0.005
N75.0 Cyst of Bartholin's gland	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
S86.0 Injury of Achilles tendon	0.000	0.995	0.005
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.995	0.005
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.995	0.005
H18.6 Keratoconus	0.000	0.995	0.005
S82.70 Multiple fractures of lower leg (closed)	0.001	0.995	0.005
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.995	0.005
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.995	0.005
S80 Superficial injury of lower leg	0.000	0.995	0.005
S87.0 Crushing injury of knee	0.000	0.995	0.005
H18.3 Changes in corneal membranes	0.000	0.995	0.005
F25.2 Schizoaffective disorder, mixed type	0.005	0.995	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.995	0.005
G44.2 Tension-type headache	0.000	0.995	0.005
F20.9 Schizophrenia, unspecified	0.005	0.995	0.000
H18.7 Other corneal deformities	0.000	0.995	0.005
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.995	0.004
S89.8 Other specified injuries of lower leg	0.000	0.995	0.004
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.995	0.005
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
F25.0 Schizoaffective disorder, manic type	0.004	0.995	0.000
F20 Schizophrenia	0.004	0.995	0.000
H18.1 Bullous keratopathy	0.000	0.996	0.004
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
F25.8 Other schizoaffective disorders	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.996	0.004
H18.0 Corneal pigmentations and deposits	0.000	0.996	0.004
H18.2 Other corneal oedema	0.000	0.996	0.004
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.996	0.004
L27.8 Dermatitis due to other substances taken internally	0.000	0.996	0.004
L27.2 Dermatitis due to ingested food	0.000	0.996	0.004
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.996	0.004
E85.4 Organ-limited amyloidosis	0.004	0.996	0.000
G51.0 Bell's palsy	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.004	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.996	0.004
F20.5 Residual schizophrenia	0.004	0.996	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.996	0.004
I22 Subsequent myocardial infarction	0.004	0.996	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.996	0.004
F20.8 Other schizophrenia	0.004	0.996	0.000
G50.0 Trigeminal neuralgia	0.004	0.996	0.000
N21.1 Calculus in urethra	0.004	0.996	0.000
H16.0 Corneal ulcer	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
F20.6 Simple schizophrenia	0.003	0.996	0.000
F20.4 Postschizophrenic depression	0.003	0.996	0.000
F20.3 Undifferentiated schizophrenia	0.003	0.996	0.000
F20.2 Catatonic schizophrenia	0.003	0.996	0.000
F20.1 Hebephrenic schizophrenia	0.003	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.996	0.003
N21.8 Other lower urinary tract calculus	0.003	0.996	0.000
I22.8 Subsequent myocardial infarction of other sites	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
N21 Calculus of lower urinary tract	0.003	0.997	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.997	0.003
N21.0 Calculus in bladder	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
K90.0 Coeliac disease	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
G51.3 Clonic hemifacial spasm	0.000	0.997	0.003
G80.9 Infantile cerebral palsy, unspecified	0.000	0.997	0.003
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.003	0.997	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.003	0.997	0.000
S63.5 Sprain and strain of wrist	0.003	0.997	0.000
H18.4 Corneal degeneration	0.000	0.997	0.003
F28 Other nonorganic psychotic disorders	0.003	0.997	0.000
F24 Induced delusional disorder	0.003	0.997	0.000
F21 Schizotypal disorder	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
F31 Bipolar affective disorder	0.003	0.997	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.003	0.997	0.000
S63.0 Dislocation of wrist	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
I08 Multiple valve diseases	0.000	0.997	0.003
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.997	0.003
G51 Facial nerve disorders	0.000	0.997	0.003
N75.1 Abscess of Bartholin's gland	0.003	0.997	0.000
K63.1 Perforation of intestine (nontraumatic)	0.003	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.997	0.003
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D41.4 Bladder	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
F22 Persistent delusional disorders	0.002	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.997	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.997	0.000
S63.2 Multiple dislocations of fingers	0.002	0.997	0.000
K90 Intestinal malabsorption	0.003	0.997	0.000
D36.7 Other specified sites	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.002	0.997	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.997	0.003
T88.4 Failed or difficult intubation	0.003	0.997	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.002	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
E85.8 Other amyloidosis	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.998	0.000
N75.8 Other diseases of Bartholin's gland	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
I08.8 Other multiple valve diseases	0.000	0.998	0.002
H16 Keratitis	0.000	0.998	0.002
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.998	0.002
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.998	0.002
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
G51.4 Facial myokymia	0.000	0.998	0.002
G51.2 Melkersson's syndrome	0.000	0.998	0.002
G51.1 Geniculate ganglionitis	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
G51.9 Disorder of facial nerve, unspecified	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
K90.3 Pancreatic steatorrhoea	0.002	0.998	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.002	0.998	0.000
K90.1 Tropical sprue	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.998	0.002
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.998	0.002
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
F61 Mixed and other personality disorders	0.002	0.998	0.000
F99-F99 Unspecified mental disorder	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.998	0.002
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.998	0.002
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
H13.3 Ocular pemphigoid	0.002	0.998	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
K90.8 Other intestinal malabsorption	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.998	0.002
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
G51.8 Other disorders of facial nerve	0.000	0.998	0.002
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
Z11.5 Special screening examination for other viral diseases	0.000	0.998	0.002
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.000	0.998	0.002
H17 Corneal scars and opacities	0.000	0.998	0.002
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.998	0.002
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.998	0.002
C32.9 Larynx, unspecified	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.998	0.002
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.000	0.998	0.002
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.001	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.001	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.001	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.001	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
Chapter V Mental and behavioural disorders	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
F33 Recurrent depressive disorder	0.002	0.998	0.000
F62.9 Enduring personality change, unspecified	0.002	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
F01 Vascular dementia	0.002	0.998	0.000
H16.8 Other keratitis	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.001	0.998	0.000
F62.8 Other enduring personality changes	0.002	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.002	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.002	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations