TreeWAS – Variant ID: rs13396519

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.984	0.016
C71.2 Temporal lobe	0.011	0.989	0.000
C71 Malignant neoplasm of brain	0.010	0.990	0.000
C71.1 Frontal lobe	0.010	0.990	0.000
T78.4 Allergy, unspecified	0.000	0.991	0.009
C71.9 Brain, unspecified	0.008	0.992	0.000
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.992	0.008
C71.8 Overlapping lesion of brain	0.008	0.992	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.992	0.008
C71.7 Brain stem	0.007	0.993	0.000
C71.6 Cerebellum	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
C71.4 Occipital lobe	0.007	0.993	0.000
T78.3 Angioneurotic oedema	0.000	0.993	0.007
R73.0 Abnormal glucose tolerance test	0.007	0.993	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.993	0.007
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
T78.9 Adverse effect, unspecified	0.000	0.994	0.006
T78.8 Other adverse effects, not elsewhere classified	0.000	0.994	0.006
I71 Aortic aneurysm and dissection	0.000	0.994	0.006
K62.0 Anal polyp	0.006	0.994	0.000
H25.1 Senile nuclear cataract	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.994	0.006
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.995	0.005
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.995	0.005
S52.10 Fracture of upper end of radius (closed)	0.005	0.995	0.000
K90 Intestinal malabsorption	0.000	0.995	0.005
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.995	0.005
C71.3 Parietal lobe	0.004	0.995	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.005
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.995	0.004
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.995	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.995	0.004
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
J30.3 Other allergic rhinitis	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.996	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.996	0.004
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.996	0.004
K90.1 Tropical sprue	0.000	0.996	0.004
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
K90.8 Other intestinal malabsorption	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
D68 Other coagulation defects	0.004	0.996	0.000
H35.3 Degeneration of macula and posterior pole	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.996	0.004
R21 Rash and other nonspecific skin eruption	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.000	0.996	0.004
I35.0 Aortic (valve) stenosis	0.000	0.996	0.004
D68.0 Von Willebrand's disease	0.003	0.996	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.996	0.003
D68.9 Coagulation defect, unspecified	0.003	0.997	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.997	0.003
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.997	0.003
H25.9 Senile cataract, unspecified	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.997	0.003
O42 Premature rupture of membranes	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.003	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
H34 Retinal vascular occlusions	0.003	0.997	0.000
J30 Vasomotor and allergic rhinitis	0.003	0.997	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.997	0.003
D68.5 Primary Thrombophilia	0.003	0.997	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.997	0.003
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.997	0.003
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
T75 Effects of other external causes	0.000	0.997	0.003
T74 Maltreatment syndromes	0.000	0.997	0.003
T73 Effects of other deprivation	0.000	0.997	0.003
T70 Effects of air pressure and water pressure	0.000	0.997	0.003
T69 Other effects of reduced temperature	0.000	0.997	0.003
T67 Effects of heat and light	0.000	0.997	0.003
T71 Asphyxiation	0.000	0.997	0.003
T66 Unspecified effects of radiation	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
T68 Hypothermia	0.000	0.997	0.003
H25 Senile cataract	0.000	0.997	0.003
I35.8 Other aortic valve disorders	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
D12.8 Rectum	0.000	0.997	0.003
M25.96 Joint disorder, unspecified (Lower leg)	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.997	0.000
C69.6 Orbit	0.002	0.997	0.000
C69.5 Lachrymal gland and duct	0.002	0.997	0.000
C69.4 Ciliary body	0.002	0.997	0.000
C69.2 Retina	0.002	0.997	0.000
C69.1 Cornea	0.002	0.997	0.000
C69.0 Conjunctiva	0.002	0.997	0.000
C70.9 Meninges, unspecified	0.002	0.997	0.000
C70.1 Spinal meninges	0.002	0.997	0.000
C70.0 Cerebral meninges	0.002	0.997	0.000
C72.9 Central nervous system, unspecified	0.002	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.997	0.000
C72.4 Acoustic nerve	0.002	0.997	0.000
C72.3 Optic nerve	0.002	0.997	0.000
C72.2 Olfactory nerve	0.002	0.997	0.000
C72.1 Cauda equina	0.002	0.997	0.000
C72.0 Spinal cord	0.002	0.997	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.997	0.000
T59.8 Other specified gases, fumes and vapours	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.997	0.002
S52.1 Fracture of upper end of radius	0.002	0.997	0.000
H35 Other retinal disorders	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.002	0.997	0.000
J30.0 Vasomotor rhinitis	0.002	0.997	0.000
H35.6 Retinal haemorrhage	0.002	0.997	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
H35.7 Separation of retinal layers	0.002	0.997	0.000
Z87.8 Personal history of other specified conditions	0.000	0.997	0.003
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.002	0.998	0.000
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
H81.0 Meniere's disease	0.000	0.998	0.002
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
H31 Other disorders of choroid	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.002
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.002
T67.8 Other effects of heat and light	0.000	0.998	0.002
T67.7 Heat oedema	0.000	0.998	0.002
T67.6 Heat fatigue, transient	0.000	0.998	0.002
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.002
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.002
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.002
T67.2 Heat cramp	0.000	0.998	0.002
T67.1 Heat syncope	0.000	0.998	0.002
T67.0 Heatstroke and sunstroke	0.000	0.998	0.002
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.002
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.002
T69.1 Chilblains	0.000	0.998	0.002
T69.0 Immersion hand and foot	0.000	0.998	0.002
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.002
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.002
T70.4 Effects of high-pressure fluids	0.000	0.998	0.002
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.002
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.002
T70.1 Sinus barotrauma	0.000	0.998	0.002
T70.0 Otitic barotrauma	0.000	0.998	0.002
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.002
T73.8 Other effects of deprivation	0.000	0.998	0.002
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.002
T73.2 Exhaustion due to exposure	0.000	0.998	0.002
T73.1 Effects of thirst	0.000	0.998	0.002
T73.0 Effects of hunger	0.000	0.998	0.002
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.002
T74.8 Other maltreatment syndromes	0.000	0.998	0.002
T74.3 Psychological abuse	0.000	0.998	0.002
T74.2 Sexual abuse	0.000	0.998	0.002
T74.1 Physical abuse	0.000	0.998	0.002
T74.0 Neglect or abandonment	0.000	0.998	0.002
T75.8 Other specified effects of external causes	0.000	0.998	0.002
T75.4 Effects of electric current	0.000	0.998	0.002
T75.3 Motion sickness	0.000	0.998	0.002
T75.2 Effects of vibration	0.000	0.998	0.002
T75.1 Drowning and nonfatal submersion	0.000	0.998	0.002
T75.0 Effects of lightning	0.000	0.998	0.002
H25.2 Senile cataract, morgagnian type	0.000	0.998	0.002
C69.3 Choroid	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
H31.3 Choroidal haemorrhage and rupture	0.002	0.998	0.000
H25.8 Other senile cataract	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
D23.7 Skin of lower limb, including hip	0.002	0.998	0.000
R73 Elevated blood glucose level	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.002	0.998	0.000
C50.1 Central portion of breast	0.000	0.998	0.002
H31.9 Disorder of choroid, unspecified	0.002	0.998	0.000
H31.4 Choroidal detachment	0.002	0.998	0.000
H31.2 Hereditary choroidal dystrophy	0.002	0.998	0.000
H31.1 Choroidal degeneration	0.002	0.998	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z87 Personal history of other diseases and conditions	0.000	0.998	0.002
D03 Melanoma in situ	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
T59 Toxic effect of other gases, fumes and vapours	0.002	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
Z87.0 Personal history of diseases of the respiratory system	0.000	0.998	0.002
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.001	0.998	0.000
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
H32 Chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H30 Chorioretinal inflammation	0.002	0.998	0.000
K90-K93 Other diseases of the digestive system	0.000	0.998	0.002
C44.1 Skin of eyelid, including canthus	0.000	0.998	0.002
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
D03.9 Melanoma in situ, unspecified	0.001	0.998	0.000
D03.8 Melanoma in situ of other sites	0.001	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.001	0.998	0.000
D03.0 Melanoma in situ of lip	0.001	0.998	0.000
H35.5 Hereditary retinal dystrophy	0.001	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.998	0.002
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
I42 Cardiomyopathy	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
S52.50 Fracture of lower end of radius (closed)	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.001
Z87.1 Personal history of diseases of the digestive system	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
R52.0 Acute pain	0.000	0.998	0.002
M25.99 Joint disorder, unspecified (Site unspecified)	0.001	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.001	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.001	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.001	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.001	0.998	0.000
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.001	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.000	0.998	0.001
T59.9 Gases, fumes and vapours, unspecified	0.001	0.998	0.000
T59.7 Carbon dioxide	0.001	0.998	0.000
T59.6 Hydrogen sulphide	0.001	0.998	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.001	0.998	0.000
T59.4 Chlorine gas	0.001	0.998	0.000
T59.3 Lachrymogenic gas	0.001	0.998	0.000
T59.2 Formaldehyde	0.001	0.998	0.000
T59.1 Sulphur dioxide	0.001	0.998	0.000
T59.0 Nitrogen oxides	0.001	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.001	0.998	0.000
D09.0 Bladder	0.001	0.998	0.000
M89.9 Disorder of bone, unspecified	0.001	0.998	0.000
T56.8 Other metals	0.001	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.001
R52.1 Chronic intractable pain	0.000	0.998	0.002
H30.9 Chorioretinal inflammation, unspecified	0.001	0.999	0.000
H30.8 Other chorioretinal inflammations	0.001	0.999	0.000
H30.2 Posterior cyclitis	0.001	0.999	0.000
H30.1 Disseminated chorioretinal inflammation	0.001	0.999	0.000
H30.0 Focal chorioretinal inflammation	0.001	0.999	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.001	0.999	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.999	0.001
M25.97 Joint disorder, unspecified (Ankle and foot)	0.001	0.999	0.000
H35.4 Peripheral retinal degeneration	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.000	0.999	0.001
N13.3 Other and unspecified hydronephrosis	0.000	0.999	0.001
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.999	0.001
I42.5 Other restrictive cardiomyopathy	0.000	0.999	0.001
I42.4 Endocardial fibroelastosis	0.000	0.999	0.001
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.999	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.999	0.001
T93.0 Sequelae of open wound of lower limb	0.001	0.999	0.000
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.999	0.001
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.999	0.001
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
H50.1 Divergent concomitant strabismus	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
R09.0 Asphyxia	0.000	0.999	0.001
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
D04.5 Skin of trunk	0.001	0.999	0.000
D09.1 Other and unspecified urinary organs	0.001	0.999	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.999	0.001
K93.1 Megacolon in Chagas' disease	0.000	0.999	0.001
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.999	0.001
D09 Carcinoma in situ of other and unspecified sites	0.001	0.999	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.999	0.001
I83.1 Varicose veins of lower extremities with inflammation	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.999	0.001
D01.2 Rectum	0.001	0.999	0.000
I44.1 Atrioventricular block, second degree	0.000	0.999	0.001
L89.0 Stage I decubitus ulcer and pressure area	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
W10.8 Other specified place	0.001	0.999	0.000
I42.8 Other cardiomyopathies	0.000	0.999	0.001
D04 Carcinoma in situ of skin	0.001	0.999	0.000
C77.8 Lymph nodes of multiple regions	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
D09.9 Carcinoma in situ, unspecified	0.001	0.999	0.000
D09.7 Carcinoma in situ of other specified sites	0.001	0.999	0.000
D09.3 Thyroid and other endocrine glands	0.001	0.999	0.000
D09.2 Eye	0.001	0.999	0.000
T56 Toxic effect of metals	0.001	0.999	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
D01.3 Anus and anal canal	0.001	0.999	0.000
H52.0 Hypermetropia	0.000	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
D04.6 Skin of upper limb, including shoulder	0.001	0.999	0.000
D04.3 Skin of other and unspecified parts of face	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
H52.2 Astigmatism	0.000	0.999	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.999	0.000
R63.0 Anorexia	0.000	0.999	0.001
Y83.8 Other surgical procedures	0.000	0.999	0.001
D01 Carcinoma in situ of other and unspecified digestive organs	0.001	0.999	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
D04.9 Skin, unspecified	0.001	0.999	0.000
D04.8 Skin of other sites	0.001	0.999	0.000
D04.2 Skin of ear and external auricular canal	0.001	0.999	0.000
D04.1 Skin of eyelid, including canthus	0.001	0.999	0.000
D04.0 Skin of lip	0.001	0.999	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.000	0.999	0.001
Z04.3 Examination and observation following other accident	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
T56.9 Metal, unspecified	0.001	0.999	0.000
T56.7 Beryllium and its compounds	0.001	0.999	0.000
T56.6 Tin and its compounds	0.001	0.999	0.000
T56.5 Zinc and its compounds	0.001	0.999	0.000
T56.4 Copper and its compounds	0.001	0.999	0.000
T56.3 Cadmium and its compounds	0.001	0.999	0.000
T56.2 Chromium and its compounds	0.001	0.999	0.000
T56.1 Mercury and its compounds	0.001	0.999	0.000
T56.0 Lead and its compounds	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
D01.9 Digestive organ, unspecified	0.001	0.999	0.000
D01.7 Other specified digestive organs	0.001	0.999	0.000
D01.5 Liver, gallbladder and bile ducts	0.001	0.999	0.000
D01.4 Other and unspecified parts of intestine	0.001	0.999	0.000
D01.1 Rectosigmoid junction	0.001	0.999	0.000
D01.0 Colon	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
R52 Pain, not elsewhere classified	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.000	0.999	0.001
I89.1 Lymphangitis	0.001	0.999	0.000
R06.2 Wheezing	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.999	0.001
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.999	0.001
O41.0 Oligohydramnios	0.000	0.999	0.001
H36 Retinal disorders in diseases classified elsewhere	0.001	0.999	0.000
N13 Obstructive and reflux uropathy	0.000	0.999	0.001
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.001	0.999	0.000
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.999	0.001
J39.8 Other specified diseases of upper respiratory tract	0.000	0.999	0.001
M89.0 Algoneurodystrophy	0.001	0.999	0.000
R52.2 Other chronic pain	0.000	0.999	0.001
S82.1 Fracture of upper end of tibia	0.000	0.999	0.001
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
F45.8 Other somatoform disorders	0.000	0.999	0.001
G90.2 Horner's syndrome	0.000	0.999	0.001
H36.8 Other retinal disorders in diseases classified elsewhere	0.001	0.999	0.000
K75.0 Abscess of liver	0.001	0.999	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.999	0.001
Z47.8 Other specified orthopaedic follow-up care	0.001	0.999	0.000
H50 Other strabismus	0.000	0.999	0.001
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
M71.38 Other bursal cyst (Other)	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.999	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.999	0.000
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.999	0.001
K42.0 Umbilical hernia with obstruction, without gangrene	0.001	0.999	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.999	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations