TreeWAS – Variant ID: rs133980

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27 Other disorders of adrenal gland	0.113	0.887	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.111	0.889	0.000
E20-E35 Disorders of other endocrine glands	0.110	0.890	0.000
E27.1 Primary adrenocortical insufficiency	0.107	0.893	0.000
E28 Ovarian dysfunction	0.104	0.896	0.000
E26 Hyperaldosteronism	0.103	0.897	0.000
E28.2 Polycystic ovarian syndrome	0.100	0.900	0.000
E26.0 Primary hyperaldosteronism	0.095	0.905	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.091	0.908	0.000
E27.2 Addisonian crisis	0.090	0.910	0.000
E32 Diseases of thymus	0.089	0.911	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.089	0.911	0.000
E22 Hyperfunction of pituitary gland	0.088	0.912	0.000
E20 Hypoparathyroidism	0.086	0.913	0.000
E26.9 Hyperaldosteronism, unspecified	0.084	0.916	0.000
E24 Cushing's syndrome	0.083	0.917	0.000
E27.5 Adrenomedullary hyperfunction	0.081	0.919	0.000
E27.0 Other adrenocortical overactivity	0.081	0.919	0.000
E25 Adrenogenital disorders	0.080	0.920	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.079	0.921	0.000
E30 Disorders of puberty, not elsewhere classified	0.079	0.921	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.078	0.922	0.000
E27.8 Other specified disorders of adrenal gland	0.076	0.923	0.000
E31 Polyglandular dysfunction	0.076	0.924	0.000
E28.9 Ovarian dysfunction, unspecified	0.074	0.925	0.000
E28.8 Other ovarian dysfunction	0.074	0.925	0.000
E28.1 Androgen excess	0.074	0.925	0.000
E28.0 Oestrogen excess	0.074	0.925	0.000
E21.0 Primary hyperparathyroidism	0.074	0.926	0.000
E26.8 Other hyperaldosteronism	0.074	0.926	0.000
E26.1 Secondary hyperaldosteronism	0.074	0.926	0.000
E20.1 Pseudohypoparathyroidism	0.073	0.927	0.000
E28.3 Primary ovarian failure	0.072	0.928	0.000
E32.9 Disease of thymus, unspecified	0.071	0.929	0.000
E34 Other endocrine disorders	0.070	0.930	0.000
E32.8 Other diseases of thymus	0.069	0.931	0.000
E29 Testicular dysfunction	0.068	0.932	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.067	0.932	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.065	0.935	0.000
E22.1 Hyperprolactinaemia	0.065	0.935	0.000
E23 Hypofunction and other disorders of pituitary gland	0.065	0.935	0.000
E21.3 Hyperparathyroidism, unspecified	0.065	0.935	0.000
E24.9 Cushing's syndrome, unspecified	0.065	0.935	0.000
E32.1 Abscess of thymus	0.064	0.936	0.000
E32.0 Persistent hyperplasia of thymus	0.064	0.936	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.064	0.936	0.000
E24.8 Other Cushing's syndrome	0.064	0.936	0.000
E34.8 Other specified endocrine disorders	0.063	0.936	0.000
E22.8 Other hyperfunction of pituitary gland	0.063	0.937	0.000
E21.2 Other hyperparathyroidism	0.063	0.937	0.000
E20.8 Other hypoparathyroidism	0.062	0.938	0.000
E20.0 Idiopathic hypoparathyroidism	0.062	0.938	0.000
E24.0 Pituitary-dependent Cushing's disease	0.061	0.939	0.000
R42 Dizziness and giddiness	0.061	0.939	0.000
E21.4 Other specified disorders of parathyroid gland	0.060	0.939	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.059	0.940	0.000
E24.3 Ectopic ACTH syndrome	0.059	0.940	0.000
E24.1 Nelson's syndrome	0.059	0.940	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.059	0.941	0.000
E25.9 Adrenogenital disorder, unspecified	0.058	0.942	0.000
E25.8 Other adrenogenital disorders	0.058	0.942	0.000
E20.9 Hypoparathyroidism, unspecified	0.057	0.943	0.000
E30.9 Disorder of puberty, unspecified	0.057	0.943	0.000
E30.8 Other disorders of puberty	0.057	0.943	0.000
E30.1 Precocious puberty	0.057	0.943	0.000
E30.0 Delayed puberty	0.057	0.943	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.057	0.943	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.057	0.943	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.057	0.943	0.000
E31.9 Polyglandular dysfunction, unspecified	0.055	0.945	0.000
E31.8 Other polyglandular dysfunction	0.055	0.945	0.000
E31.1 Polyglandular hyperfunction	0.055	0.945	0.000
E34.3 Short stature, not elsewhere classified	0.052	0.948	0.000
E31.0 Autoimmune polyglandular failure	0.052	0.948	0.000
E24.2 Drug-induced Cushing's syndrome	0.051	0.949	0.000
E34.5 Androgen resistance syndrome	0.050	0.949	0.000
E34.4 Constitutional tall stature	0.050	0.949	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.050	0.949	0.000
E34.1 Other hypersecretion of intestinal hormones	0.050	0.949	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.050	0.950	0.000
E23.6 Other disorders of pituitary gland	0.049	0.951	0.000
E29.8 Other testicular dysfunction	0.049	0.951	0.000
E29.0 Testicular hyperfunction	0.049	0.951	0.000
E29.9 Testicular dysfunction, unspecified	0.048	0.951	0.000
E23.2 Diabetes insipidus	0.047	0.953	0.000
E23.1 Drug-induced hypopituitarism	0.047	0.953	0.000
E23.7 Disorder of pituitary gland, unspecified	0.045	0.955	0.000
E27.9 Disorder of adrenal gland, unspecified	0.042	0.958	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.960	0.040
E29.1 Testicular hypofunction	0.038	0.962	0.000
E22.0 Acromegaly and pituitary gigantism	0.034	0.965	0.000
E34.0 Carcinoid syndrome	0.034	0.966	0.001
E23.0 Hypopituitarism	0.023	0.976	0.000
E34.9 Endocrine disorder, unspecified	0.021	0.978	0.001
I24 Other acute ischaemic heart diseases	0.000	0.987	0.013
B35.3 Tinea pedis	0.011	0.989	0.000
B18.2 Chronic viral hepatitis C	0.000	0.990	0.010
Z48.8 Other specified surgical follow-up care	0.009	0.991	0.000
I24.1 Dressler's syndrome	0.000	0.991	0.009
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.991	0.009
C16.0 Cardia	0.000	0.991	0.009
I24.8 Other forms of acute ischaemic heart disease	0.000	0.991	0.009
B35 Dermatophytosis	0.007	0.992	0.000
N80.8 Other endometriosis	0.007	0.993	0.000
G59.0 Diabetic mononeuropathy	0.000	0.993	0.007
C15.9 Oesophagus, unspecified	0.000	0.993	0.007
B18 Chronic viral hepatitis	0.000	0.993	0.007
N80.2 Endometriosis of Fallopian tube	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
N80.1 Endometriosis of ovary	0.006	0.994	0.000
G93.2 Benign intracranial hypertension	0.006	0.994	0.000
N80 Endometriosis	0.006	0.994	0.000
B35.1 Tinea unguium	0.006	0.994	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.994	0.006
B35.8 Other dermatophytoses	0.006	0.994	0.000
B35.5 Tinea imbricata	0.006	0.994	0.000
B35.2 Tinea manuum	0.006	0.994	0.000
B35.0 Tinea barbae and tinea capitis	0.006	0.994	0.000
B35.4 Tinea corporis	0.005	0.994	0.000
B35.9 Dermatophytosis, unspecified	0.005	0.994	0.000
C16 Malignant neoplasm of stomach	0.000	0.994	0.006
C15 Malignant neoplasm of oesophagus	0.000	0.995	0.005
B35.6 Tinea cruris	0.005	0.995	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.005	0.995	0.000
N80.5 Endometriosis of intestine	0.005	0.995	0.000
F33.9 Recurrent depressive disorder, unspecified	0.005	0.995	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.995	0.005
N80.6 Endometriosis in cutaneous scar	0.005	0.995	0.000
B49 Unspecified mycosis	0.005	0.995	0.000
B18.8 Other chronic viral hepatitis	0.000	0.995	0.005
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.995	0.005
C16.4 Pylorus	0.000	0.995	0.005
C23 Malignant neoplasm of gallbladder	0.000	0.995	0.005
D86 Sarcoidosis	0.005	0.995	0.000
E46 Unspecified protein-energy malnutrition	0.005	0.995	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.995	0.005
R40.0 Somnolence	0.000	0.995	0.005
B35-B49 Mycoses	0.005	0.995	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.995	0.005
B36.9 Superficial mycosis, unspecified	0.005	0.995	0.000
C17.2 Ileum	0.000	0.995	0.005
B36 Other superficial mycoses	0.005	0.995	0.000
C15.5 Lower third of oesophagus	0.000	0.995	0.005
C15-C26 Malignant neoplasms of digestive organs	0.000	0.995	0.005
D86.8 Sarcoidosis of other and combined sites	0.005	0.995	0.000
C15.0 Cervical part of oesophagus	0.000	0.995	0.004
C24.1 Ampulla of Vater	0.000	0.996	0.004
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.996	0.004
C16.6 Greater curvature of stomach, unspecified	0.000	0.996	0.004
C24.0 Extrahepatic bile duct	0.000	0.996	0.004
C17 Malignant neoplasm of small intestine	0.000	0.996	0.004
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
C15.3 Upper third of oesophagus	0.000	0.996	0.004
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.996	0.004
C16.1 Fundus of stomach	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
C16.3 Pyloric antrum	0.000	0.996	0.004
Q89.2 Congenital malformations of other endocrine glands	0.000	0.996	0.004
C15.8 Overlapping lesion of oesophagus	0.000	0.996	0.004
C15.2 Abdominal part of oesophagus	0.000	0.996	0.004
Y54.4 Loop [high-ceiling] diuretics	0.000	0.996	0.004
C24.9 Biliary tract, unspecified	0.000	0.996	0.004
O36.0 Maternal care for rhesus isoimmunisation	0.004	0.996	0.000
C16.2 Body of stomach	0.000	0.996	0.004
O36.6 Maternal care for excessive foetal growth	0.004	0.996	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.996	0.004
C16.5 Lesser curvature of stomach, unspecified	0.000	0.996	0.004
N80.0 Endometriosis of uterus	0.004	0.996	0.000
C24.8 Overlapping lesion of biliary tract	0.000	0.996	0.004
B48 Other mycoses, not elsewhere classified	0.004	0.996	0.000
B47 Mycetoma	0.004	0.996	0.000
B46 Zygomycosis	0.004	0.996	0.000
B45 Cryptococcosis	0.004	0.996	0.000
B43 Chromomycosis and phaeomycotic abscess	0.004	0.996	0.000
B42 Sporotrichosis	0.004	0.996	0.000
B41 Paracoccidioidomycosis	0.004	0.996	0.000
B40 Blastomycosis	0.004	0.996	0.000
B39 Histoplasmosis	0.004	0.996	0.000
B38 Coccidioidomycosis	0.004	0.996	0.000
O03.4 Incomplete, without complication	0.004	0.996	0.000
E40-E46 Malnutrition	0.004	0.996	0.000
B36.8 Other specified superficial mycoses	0.003	0.996	0.000
B36.3 Black piedra	0.003	0.996	0.000
B36.2 White piedra	0.003	0.996	0.000
B36.1 Tinea nigra	0.003	0.996	0.000
B36.0 Pityriasis versicolor	0.003	0.996	0.000
C17.9 Small intestine, unspecified	0.000	0.996	0.004
B44 Aspergillosis	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.000	0.996	0.003
C26.9 Ill-defined sites within the digestive system	0.000	0.996	0.004
C16.8 Overlapping lesion of stomach	0.000	0.996	0.003
C15.4 Middle third of oesophagus	0.000	0.997	0.003
G58.9 Mononeuropathy, unspecified	0.003	0.997	0.000
C16.9 Stomach, unspecified	0.000	0.997	0.003
C17.8 Overlapping lesion of small intestine	0.000	0.997	0.003
C17.3 Meckel's diverticulum	0.000	0.997	0.003
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.997	0.003
C26.8 Overlapping lesion of digestive system	0.000	0.997	0.003
C26.1 Spleen	0.000	0.997	0.003
F33 Recurrent depressive disorder	0.003	0.997	0.000
C17.0 Duodenum	0.000	0.997	0.003
K85.9 Acute pancreatitis, unspecified	0.003	0.997	0.000
B44.1 Other pulmonary aspergillosis	0.003	0.997	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.997	0.003
R04.0 Epistaxis	0.000	0.997	0.003
B38.9 Coccidioidomycosis, unspecified	0.003	0.997	0.000
B38.8 Other forms of coccidioidomycosis	0.003	0.997	0.000
B38.7 Disseminated coccidioidomycosis	0.003	0.997	0.000
B38.4 Coccidioidomycosis meningitis	0.003	0.997	0.000
B38.3 Cutaneous coccidioidomycosis	0.003	0.997	0.000
B38.2 Pulmonary coccidioidomycosis, unspecified	0.003	0.997	0.000
B38.1 Chronic pulmonary coccidioidomycosis	0.003	0.997	0.000
B38.0 Acute pulmonary coccidioidomycosis	0.003	0.997	0.000
B39.9 Histoplasmosis, unspecified	0.003	0.997	0.000
B39.5 Histoplasmosis duboisii	0.003	0.997	0.000
B39.4 Histoplasmosis capsulati, unspecified	0.003	0.997	0.000
B39.3 Disseminated histoplasmosis capsulati	0.003	0.997	0.000
B39.2 Pulmonary histoplasmosis capsulati, unspecified	0.003	0.997	0.000
B39.1 Chronic pulmonary histoplasmosis capsulati	0.003	0.997	0.000
B39.0 Acute pulmonary histoplasmosis capsulati	0.003	0.997	0.000
B40.9 Blastomycosis, unspecified	0.003	0.997	0.000
B40.8 Other forms of blastomycosis	0.003	0.997	0.000
B40.7 Disseminated blastomycosis	0.003	0.997	0.000
B40.3 Cutaneous blastomycosis	0.003	0.997	0.000
B40.2 Pulmonary blastomycosis, unspecified	0.003	0.997	0.000
B40.1 Chronic pulmonary blastomycosis	0.003	0.997	0.000
B40.0 Acute pulmonary blastomycosis	0.003	0.997	0.000
B41.9 Paracoccidioidomycosis, unspecified	0.003	0.997	0.000
B41.8 Other forms of paracoccidioidomycosis	0.003	0.997	0.000
B41.7 Disseminated paracoccidioidomycosis	0.003	0.997	0.000
B41.0 Pulmonary paracoccidioidomycosis	0.003	0.997	0.000
B42.9 Sporotrichosis, unspecified	0.003	0.997	0.000
B42.8 Other forms of sporotrichosis	0.003	0.997	0.000
B42.7 Disseminated sporotrichosis	0.003	0.997	0.000
B42.1 Lymphocutaneous sporotrichosis	0.003	0.997	0.000
B42.0 Pulmonary sporotrichosis	0.003	0.997	0.000
B43.9 Chromomycosis, unspecified	0.003	0.997	0.000
B43.8 Other forms of chromomycosis	0.003	0.997	0.000
B43.2 Subcutaneous phaeomycotic abscess and cyst	0.003	0.997	0.000
B43.1 Phaeomycotic brain abscess	0.003	0.997	0.000
B43.0 Cutaneous chromomycosis	0.003	0.997	0.000
B45.9 Cryptococcosis, unspecified	0.003	0.997	0.000
B45.8 Other forms of cryptococcosis	0.003	0.997	0.000
B45.7 Disseminated cryptococcosis	0.003	0.997	0.000
B45.3 Osseous cryptococcosis	0.003	0.997	0.000
B45.2 Cutaneous cryptococcosis	0.003	0.997	0.000
B45.1 Cerebral cryptococcosis	0.003	0.997	0.000
B45.0 Pulmonary cryptococcosis	0.003	0.997	0.000
B46.9 Zygomycosis, unspecified	0.003	0.997	0.000
B46.8 Other zygomycoses	0.003	0.997	0.000
B46.5 Mucormycosis, unspecified	0.003	0.997	0.000
B46.4 Disseminated mucormycosis	0.003	0.997	0.000
B46.3 Cutaneous mucormycosis	0.003	0.997	0.000
B46.2 Gastro-intestinal mucormycosis	0.003	0.997	0.000
B46.1 Rhinocerebral mucormycosis	0.003	0.997	0.000
B46.0 Pulmonary mucormycosis	0.003	0.997	0.000
B47.9 Mycetoma, unspecified	0.003	0.997	0.000
B47.1 Actinomycetoma	0.003	0.997	0.000
B47.0 Eumycetoma	0.003	0.997	0.000
B48.8 Other specified mycoses	0.003	0.997	0.000
B48.7 Opportunistic mycoses	0.003	0.997	0.000
B48.4 Penicillosis	0.003	0.997	0.000
B48.3 Geotrichosis	0.003	0.997	0.000
B48.2 Allescheriasis	0.003	0.997	0.000
B48.1 Rhinosporidiosis	0.003	0.997	0.000
B48.0 Lobomycosis	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.003	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.003	0.997	0.000
E42 Marasmic kwashiorkor	0.003	0.997	0.000
E41 Nutritional marasmus	0.003	0.997	0.000
E40 Kwashiorkor	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
R80 Isolated proteinuria	0.003	0.997	0.000
B44.8 Other forms of aspergillosis	0.003	0.997	0.000
B44.7 Disseminated aspergillosis	0.003	0.997	0.000
B44.2 Tonsillar aspergillosis	0.003	0.997	0.000
B44.0 Invasive pulmonary aspergillosis	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.997	0.003
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
O36.4 Maternal care for intra-uterine death	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
M84.0 Malunion of fracture	0.000	0.997	0.003
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
C17.1 Jejunum	0.000	0.997	0.002
O36.9 Maternal care for foetal problem, unspecified	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
H91.8 Other specified hearing loss	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
D84 Other immunodeficiencies	0.002	0.997	0.000
K37 Unspecified appendicitis	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.998	0.002
G59.8 Other mononeuropathies in diseases classified elsewhere	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.002
I05.0 Mitral stenosis	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
S82.30 Fracture of lower end of tibia (closed)	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
B15-B19 Viral hepatitis	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.998	0.002
H18.4 Corneal degeneration	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
C62.9 Testis, unspecified	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
K62.7 Radiation proctitis	0.000	0.998	0.002
W29.9 Unspecified place	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.002
Q89.8 Other specified congenital malformations	0.000	0.998	0.002
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.002
Q89.4 Conjoined twins	0.000	0.998	0.002
Q89.3 Situs inversus	0.000	0.998	0.002
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.002
Q89.0 Congenital malformations of spleen	0.000	0.998	0.002
B19 Unspecified viral hepatitis	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
B16 Acute hepatitis B	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.000	0.998	0.002
C22.7 Other specified carcinomas of liver	0.000	0.998	0.002
C22.4 Other sarcomas of liver	0.000	0.998	0.002
C22.3 Angiosarcoma of liver	0.000	0.998	0.002
C22.2 Hepatoblastoma	0.000	0.998	0.002
H18.1 Bullous keratopathy	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.000	0.998	0.002
B19.9 Unspecified viral hepatitis without coma	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
R06.1 Stridor	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.002
D14.0 Middle ear, nasal cavity and accessory sinuses	0.002	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
W57.0 Home	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
K85 Acute pancreatitis	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.000	0.998	0.002
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
Y54.5 Other diuretics	0.000	0.998	0.002
E65 Localised adiposity	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.001	0.998	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.998	0.001
C21.2 Cloacogenic zone	0.000	0.998	0.001
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
R40.1 Stupor	0.000	0.998	0.001
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.001
K43.9 Ventral hernia without obstruction or gangrene	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.998	0.000
S00.0 Superficial injury of scalp	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.001	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.000	0.998	0.001
K08.9 Disorder of teeth and supporting structures, unspecified	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.001	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.998	0.001
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.001
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.001
D02.0 Larynx	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.001
C49.4 Connective and soft tissue of abdomen	0.000	0.999	0.001
H61.3 Acquired stenosis of external ear canal	0.000	0.999	0.001
B15 Acute hepatitis A	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.999	0.001
O34 Maternal care for known or suspected abnormality of pelvic organs	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.999	0.001
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.999	0.001
Z98.8 Other specified postsurgical states	0.001	0.999	0.000
E67 Other hyperalimentation	0.001	0.999	0.000
E68 Sequelae of hyperalimentation	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
E16.1 Other hypoglycaemia	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations