TreeWAS – Variant ID: rs1376359

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.000	0.259	0.741
H40 Glaucoma	0.000	0.330	0.670
H40.2 Primary angle-closure glaucoma	0.000	0.338	0.662
H35.0 Background retinopathy and retinal vascular changes	0.623	0.377	0.000
H35 Other retinal disorders	0.614	0.386	0.000
H35.3 Degeneration of macula and posterior pole	0.598	0.402	0.000
H40.1 Primary open-angle glaucoma	0.000	0.424	0.576
H35.7 Separation of retinal layers	0.576	0.424	0.000
H35.4 Peripheral retinal degeneration	0.549	0.451	0.000
H40.8 Other glaucoma	0.000	0.489	0.511
H35.9 Retinal disorder, unspecified	0.484	0.516	0.000
H35.6 Retinal haemorrhage	0.471	0.529	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.542	0.458
H35.1 Retinopathy of prematurity	0.440	0.560	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.566	0.434
H40.4 Glaucoma secondary to eye inflammation	0.000	0.605	0.395
H35.2 Other proliferative retinopathy	0.394	0.606	0.000
H30-H36 Disorders of choroid and retina	0.362	0.638	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.655	0.345
H36 Retinal disorders in diseases classified elsewhere	0.341	0.659	0.000
H36.0 Diabetic retinopathy	0.327	0.673	0.000
H40.0 Glaucoma suspect	0.000	0.680	0.320
H34 Retinal vascular occlusions	0.283	0.717	0.000
H35.5 Hereditary retinal dystrophy	0.281	0.718	0.000
H40-H42 Glaucoma	0.000	0.720	0.280
H31 Other disorders of choroid	0.278	0.722	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.260	0.740	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.245	0.755	0.000
H34.2 Other retinal artery occlusions	0.238	0.762	0.000
H31.1 Choroidal degeneration	0.233	0.767	0.000
H30 Chorioretinal inflammation	0.227	0.773	0.000
H34.1 Central retinal artery occlusion	0.215	0.784	0.000
H34.8 Other retinal vascular occlusions	0.205	0.795	0.000
H34.0 Transient retinal artery occlusion	0.203	0.797	0.000
H42 Glaucoma in diseases classified elsewhere	0.000	0.799	0.201
H31.4 Choroidal detachment	0.199	0.800	0.000
H31.2 Hereditary choroidal dystrophy	0.199	0.800	0.000
H31.9 Disorder of choroid, unspecified	0.199	0.801	0.000
H31.3 Choroidal haemorrhage and rupture	0.198	0.802	0.000
H31.8 Other specified disorders of choroid	0.195	0.804	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.186	0.814	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.186	0.814	0.000
H31.0 Chorioretinal scars	0.181	0.819	0.000
H30.8 Other chorioretinal inflammations	0.163	0.837	0.000
H30.1 Disseminated chorioretinal inflammation	0.163	0.837	0.000
H30.0 Focal chorioretinal inflammation	0.163	0.837	0.000
H34.9 Retinal vascular occlusion, unspecified	0.162	0.838	0.000
H35.8 Other specified retinal disorders	0.156	0.844	0.000
H30.2 Posterior cyclitis	0.156	0.844	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.856	0.144
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.856	0.144
H30.9 Chorioretinal inflammation, unspecified	0.140	0.859	0.000
H33 Retinal detachments and breaks	0.065	0.935	0.000
H33.5 Other retinal detachments	0.052	0.948	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.956	0.044
Z04.9 Examination and observation for unspecified reason	0.000	0.957	0.043
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.958	0.042
C79.2 Secondary malignant neoplasm of skin	0.000	0.958	0.042
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.959	0.041
H33.1 Retinoschisis and retinal cysts	0.040	0.960	0.000
N87.1 Moderate cervical dysplasia	0.039	0.961	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.962	0.038
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.963	0.037
H33.4 Traction detachment of retina	0.037	0.963	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.963	0.037
H33.2 Serous retinal detachment	0.036	0.964	0.000
H33.3 Retinal breaks without detachment	0.035	0.965	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.967	0.033
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.967	0.033
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.970	0.030
N87 Dysplasia of cervix uteri	0.027	0.973	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.026	0.974	0.000
Q61.3 Polycystic kidney, unspecified	0.022	0.978	0.000
Q61.2 Polycystic kidney, adult type	0.022	0.978	0.000
Q61 Cystic kidney disease	0.021	0.979	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.979	0.020
N87.2 Severe cervical dysplasia, not elsewhere classified	0.019	0.981	0.000
N87.0 Mild cervical dysplasia	0.018	0.982	0.000
Q61.0 Congenital single renal cyst	0.018	0.982	0.000
Q61.5 Medullary cystic kidney	0.017	0.982	0.000
Q61.8 Other cystic kidney diseases	0.015	0.985	0.000
Q61.1 Polycystic kidney, infantile type	0.015	0.985	0.000
Q61.4 Renal dysplasia	0.013	0.987	0.000
H33.0 Retinal detachment with retinal break	0.013	0.987	0.000
Q61.9 Cystic kidney disease, unspecified	0.011	0.989	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.009	0.991	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.009	0.991	0.000
G81.9 Hemiplegia, unspecified	0.000	0.993	0.007
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.994	0.006
G83.9 Paralytic syndrome, unspecified	0.000	0.994	0.006
G83 Other paralytic syndromes	0.000	0.994	0.006
G81 Hemiplegia	0.000	0.994	0.006
W13.9 Unspecified place	0.000	0.994	0.006
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.995	0.005
Z93.5 Cystostomy status	0.000	0.995	0.005
G82 Paraplegia and tetraplegia	0.000	0.995	0.005
L60.0 Ingrowing nail	0.000	0.995	0.005
G82.4 Spastic tetraplegia	0.000	0.995	0.005
G83.1 Monoplegia of lower limb	0.000	0.995	0.005
G83.4 Cauda equina syndrome	0.000	0.995	0.005
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.995	0.005
G83.2 Monoplegia of upper limb	0.000	0.995	0.005
R94.3 Abnormal results of cardiovascular function studies	0.000	0.995	0.005
G83.3 Monoplegia, unspecified	0.000	0.996	0.004
F80.1 Expressive language disorder	0.004	0.996	0.000
G83.5 Locked-in syndrome	0.000	0.996	0.004
G83.0 Diplegia of upper limbs	0.000	0.996	0.004
G82.2 Paraplegia, unspecified	0.000	0.996	0.004
G81.0 Flaccid hemiplegia	0.000	0.996	0.004
L40.9 Psoriasis, unspecified	0.000	0.996	0.004
T78.3 Angioneurotic oedema	0.004	0.996	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.996	0.004
G82.5 Tetraplegia, unspecified	0.000	0.996	0.004
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.996	0.004
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.996	0.004
G83.8 Other specified paralytic syndromes	0.000	0.996	0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.996	0.004
G82.3 Flaccid tetraplegia	0.000	0.996	0.004
G82.0 Flaccid paraplegia	0.000	0.996	0.004
M84.0 Malunion of fracture	0.000	0.996	0.004
Z93.8 Other artificial opening status	0.000	0.996	0.004
G80 Infantile cerebral palsy	0.000	0.996	0.004
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.996	0.004
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.996	0.000
G81.1 Spastic hemiplegia	0.000	0.996	0.004
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.996	0.004
H73.8 Other specified disorders of tympanic membrane	0.000	0.996	0.004
Z93.2 Ileostomy status	0.000	0.996	0.004
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.996	0.004
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.996	0.004
Z93 Artificial opening status	0.000	0.996	0.004
M84.01 Malunion of fracture (Shoulder region)	0.000	0.996	0.004
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.003
M84 Disorders of continuity of bone	0.000	0.997	0.003
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.997	0.003
G80.8 Other infantile cerebral palsy	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
G80.1 Spastic diplegia	0.000	0.997	0.003
F80 Specific developmental disorders of speech and language	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.997	0.003
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.000	0.997	0.003
G80.0 Spastic cerebral palsy	0.000	0.997	0.003
Z93.6 Other artificial openings of urinary tract status	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.000	0.997	0.003
M84.00 Malunion of fracture (Multiple sites)	0.000	0.997	0.003
G80.4 Ataxic cerebral palsy	0.000	0.997	0.003
G80.3 Dyskinetic cerebral palsy	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
M84.08 Malunion of fracture (Other)	0.000	0.997	0.003
F80.2 Receptive language disorder	0.003	0.997	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.000	0.997	0.003
G80.2 Infantile hemiplegia	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.003
K00.6 Disturbances in tooth eruption	0.003	0.997	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.997	0.003
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.997	0.002
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.997	0.003
E55.9 Vitamin D deficiency, unspecified	0.000	0.997	0.003
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.002
D03 Melanoma in situ	0.003	0.997	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.997	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.997	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.997	0.000
F80.0 Specific speech articulation disorder	0.002	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.997	0.000
Z93.1 Gastrostomy status	0.000	0.997	0.003
V18.1 Passenger injured in nontraffic accident	0.002	0.997	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.003	0.997	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.997	0.002
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Z93.9 Artificial opening status, unspecified	0.000	0.998	0.002
L60 Nail disorders	0.000	0.998	0.002
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.998	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.998	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.998	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.998	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.998	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.998	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.998	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.998	0.002
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.000	0.998	0.002
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.998	0.002
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.998	0.002
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.998	0.002
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.998	0.002
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.998	0.002
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.998	0.002
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
W13 Fall from, out of or through building or structure	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
V18.3 Person injured while boarding or alighting	0.002	0.998	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.998	0.002
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
Q62.5 Duplication of ureter	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
M54.56 Low back pain (Lumbar region)	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
L60.8 Other nail disorders	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
T81.9 Unspecified complication of procedure	0.000	0.998	0.002
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.002	0.998	0.000
V18.4 Driver injured in traffic accident	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
L60.3 Nail dystrophy	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
V18.5 Passenger injured in traffic accident	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.998	0.002
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.998	0.002
L60.5 Yellow nail syndrome	0.000	0.998	0.002
L60.4 Beau's lines	0.000	0.998	0.002
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
Z11.5 Special screening examination for other viral diseases	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.000	0.998	0.002
L60.9 Nail disorder, unspecified	0.000	0.998	0.002
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.998	0.002
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
L89 Decubitus ulcer	0.000	0.998	0.002
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
Z93.0 Tracheostomy status	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.998	0.002
M84.28 Delayed union of fracture (Other)	0.000	0.998	0.002
M84.24 Delayed union of fracture (Hand)	0.000	0.998	0.002
M84.23 Delayed union of fracture (Forearm)	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.998	0.002
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
L60.1 Onycholysis	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.998	0.002
H73.1 Chronic myringitis	0.000	0.998	0.002
R07.0 Pain in throat	0.002	0.998	0.000
W13.8 Other specified place	0.000	0.998	0.002
W13.0 Home	0.000	0.998	0.002
W13.7 Farm	0.000	0.998	0.002
W13.5 Trade and service area	0.000	0.998	0.002
W13.3 Sports and athletics area	0.000	0.998	0.002
W13.2 School, other institution and public administrative area	0.000	0.998	0.002
W13.1 Residential institution	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.22 Delayed union of fracture (Upper arm)	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.998	0.002
M65.34 Trigger finger-Hand	0.002	0.998	0.000
H92.1 Otorrhoea	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.998	0.000
W13.6 Industrial and construction area	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.002	0.998	0.000
W13.4 Street and highway	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.998	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.002	0.998	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.002	0.998	0.000
L60.2 Onychogryphosis	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.001	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.000	0.998	0.001
C44.9 Malignant neoplasm of skin, unspecified	0.002	0.998	0.000
L89.2 Stage III decubitus ulcer	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.998	0.002
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.002
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.998	0.002
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
O12.0 Gestational oedema	0.000	0.998	0.002
C69.9 Eye, unspecified	0.000	0.998	0.002
C69.3 Choroid	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
W13.08 Fall from, out of or through building or structure; Home; While engaged in other specified activities	0.000	0.998	0.001
W13.89 Fall from, out of or through building or structure; Other specified places; During unspecified activity	0.000	0.998	0.001
C69.2 Retina	0.000	0.998	0.002
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
M54.35 Sciatica (Thoracolumbar region)	0.001	0.998	0.000
M54.34 Sciatica-Thoracic	0.001	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.001	0.998	0.000
M54.32 Sciatica-Cervical	0.001	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.001	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
Z93.3 Colostomy status	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
F80-F89 Disorders of psychological development	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
Z71.3 Dietary counselling and surveillance	0.000	0.998	0.002
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.998	0.001
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.998	0.001
M66.06 Rupture of popliteal cyst-Lower leg	0.001	0.998	0.000
K12.1 Other forms of stomatitis	0.000	0.998	0.002
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.998	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.998	0.000
Z04 Examination and observation for other reasons	0.000	0.998	0.001
S62.5 Fracture of thumb	0.000	0.998	0.001
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.998	0.001
F84 Pervasive developmental disorders	0.001	0.999	0.000
I42.0 Dilated cardiomyopathy	0.000	0.999	0.001
C76.0 Head, face and neck	0.000	0.999	0.001
S05.9 Injury of eye and orbit, part unspecified	0.000	0.999	0.001
C69.4 Ciliary body	0.000	0.999	0.001
C76.2 Abdomen	0.000	0.999	0.001
L40.1 Generalised pustular psoriasis	0.000	0.999	0.001
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
F89 Unspecified disorder of psychological development	0.001	0.999	0.000
F88 Other disorders of psychological development	0.001	0.999	0.000
F83 Mixed specific developmental disorders	0.001	0.999	0.000
F82 Specific developmental disorder of motor function	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.000	0.999	0.001
C69.8 Overlapping lesion of eye and adnexa	0.000	0.999	0.001
C69.5 Lachrymal gland and duct	0.000	0.999	0.001
C69.1 Cornea	0.000	0.999	0.001
C76.1 Thorax	0.000	0.999	0.001
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.001	0.999	0.000
Z99.3 Dependence on wheelchair	0.000	0.999	0.001
L40.3 Pustulosis palmaris et plantaris	0.000	0.999	0.001
Q63.0 Accessory kidney	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.999	0.001
C76.7 Other ill-defined sites	0.000	0.999	0.001
C76.5 Lower limb	0.000	0.999	0.001
C76.4 Upper limb	0.000	0.999	0.001
F84.0 Childhood autism	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.999	0.001
F81 Specific developmental disorders of scholastic skills	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
X59.3 Sports and athletics area	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.999	0.001
K25 Gastric ulcer	0.001	0.999	0.000
M65.3 Trigger finger	0.001	0.999	0.000
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.999	0.001
Z04.0 Blood-alcohol and blood-drug test	0.000	0.999	0.001
L40 Psoriasis	0.000	0.999	0.001
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
F20.5 Residual schizophrenia	0.001	0.999	0.000
F84.9 Pervasive developmental disorder, unspecified	0.001	0.999	0.000
F84.8 Other pervasive developmental disorders	0.001	0.999	0.000
F84.5 Asperger's syndrome	0.001	0.999	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.001	0.999	0.000
F84.3 Other childhood disintegrative disorder	0.001	0.999	0.000
F84.2 Rett's syndrome	0.001	0.999	0.000
F84.1 Atypical autism	0.001	0.999	0.000
K25.2 Acute with both haemorrhage and perforation	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S70.1 Contusion of thigh	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.999	0.001
Z04.2 Examination and observation following work accident	0.000	0.999	0.001
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.999	0.001
E55 Vitamin D deficiency	0.000	0.999	0.001
O67.8 Other intrapartum haemorrhage	0.001	0.999	0.000
S70 Superficial injury of hip and thigh	0.001	0.999	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.999	0.001
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.999	0.001
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.999	0.001
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.000	0.999	0.001
E66.8 Other obesity	0.000	0.999	0.001
K25.1 Acute with perforation	0.001	0.999	0.000
R61.1 Generalised hyperhidrosis	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.000	0.999	0.001
Z04.1 Examination and observation following transport accident	0.000	0.999	0.001
F20 Schizophrenia	0.001	0.999	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.001	0.999	0.000
M54.36 Sciatica (Lumbar region)	0.001	0.999	0.000
C69.0 Conjunctiva	0.000	0.999	0.001
F81.8 Other developmental disorders of scholastic skills	0.001	0.999	0.000
F81.3 Mixed disorder of scholastic skills	0.001	0.999	0.000
F81.2 Specific disorder of arithmetical skills	0.001	0.999	0.000
F81.1 Specific spelling disorder	0.001	0.999	0.000
F81.0 Specific reading disorder	0.001	0.999	0.000
K08.3 Retained dental root	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.000	0.999	0.001
M79.79 Fibromyalgia (Site unspecified)	0.001	0.999	0.000
D23.9 Skin, unspecified	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
T00.9 Multiple superficial injuries, unspecified	0.000	0.999	0.001
U51.1 Previously admitted to a psychiatric hospital of the provider	0.001	0.999	0.000
W25.9 Unspecified place	0.001	0.999	0.000
R61 Hyperhidrosis	0.000	0.999	0.001
V19 Pedal cyclist injured in other and unspecified transport accidents	0.001	0.999	0.000
M65.38 Trigger finger-Other	0.001	0.999	0.000
M65.37 Trigger finger-Ankle/foot	0.001	0.999	0.000
M65.36 Trigger finger-Lower leg	0.001	0.999	0.000
M65.35 Trigger finger-Pelvic/thigh	0.001	0.999	0.000
M65.33 Trigger finger-Forearm	0.001	0.999	0.000
M65.32 Trigger finger-Upper arm	0.001	0.999	0.000
M65.31 Trigger finger-Shldr region	0.001	0.999	0.000
M65.30 Trigger finger-Mult sites	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
C76.3 Pelvis	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.999	0.001
K85.9 Acute pancreatitis, unspecified	0.001	0.999	0.000
L40.2 Acrodermatitis continua	0.000	0.999	0.001
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.999	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.999	0.000
E55.0 Rickets, active	0.000	0.999	0.001
K00.8 Other disorders of tooth development	0.001	0.999	0.000
K25.5 Chronic or unspecified with perforation	0.001	0.999	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations